Spanish National Research Council (CSIC)
Consejo Superior de Investigaciones Científicas (CSIC)


The CSIC (Spanish National Research Council) is the largest and leading public research institution in Spain and the third in Europe due to the quality and quantity of its scientific production. It plays an essential role within the Spanish System for Science, Technology and Innovation and contributes to reinforce Spain’s position at the international level.

CSIC’s main aim is to develop and promote scientific studies to contribute to foster scientific and technological progress. CSIC's mission includes:

  1. Multidisciplinary scientific and technical research
  2. Scientific and technical advice
  3. Transferring results to the private sector
  4. Contributing to the creation of technology-driven companies
  5. Training specialised personnel
  6. Management of infrastructure and large facilities
  7. Promoting scientific culture

The CSIC is multidisciplinary, carrying out research in almost all fields of knowledge. Its activities encompass basic research all the way through to technological development.

The CSIC is present in all the autonomous regions through their centres across Spain. It comprises 120 centres spread across Spain, and is also present in Brussels and Rome. It is formed by employees with a wide range of academic qualifications and professional categories. The CSIC employs 11,000 people, of which 3.000 are researchers. In total, they represent the 6% of Spain’s R&D workforce and generate approximately the 20% of the country’s production. Likewise, the CSIC collaborates with other juridical entities such as consortia and trading companies.

For more information on job opportunities at CSIC, please check our Nature Careers Employer Profile.

CSIC retains sole responsibility for content © 2021 Spanish National Research Council.

1 June 2020 - 31 May 2021

Region: Global
Subject/journal group: All

The table to the right includes counts of all research outputs for Spanish National Research Council (CSIC) published between 1 June 2020 - 31 May 2021 which are tracked by the Nature Index.

Hover over the donut graph to view the FC output for each subject. Below, the same research outputs are grouped by subject. Click on the subject to drill-down into a list of articles organized by journal, and then by title.

Note: Articles may be assigned to more than one subject area.

Count Share
1267 226.83

Outputs by subject (Share)

Subject Count Share
Physical Sciences 617 99.77
Chemistry 286 60.54
Life Sciences 376 61.38
4 0.13
5 0.44
2 0.04
1 0.01
1 0.64
15 3.17
4 0.81
7 1.18
4 0.37
7 1.29
5 1.61
3 0.16
2 0.10
4 0.92
1 0.29
7 0.24
Kidins220 deficiency causes ventriculomegaly via SNX27-retromer-dependent AQP4 degradation
Enkephalin release from VIP interneurons in the hippocampal CA2/3a region mediates heterosynaptic plasticity and social memory
Association between body mass index and subcortical brain volumes in bipolar disorders–ENIGMA study in 2735 individuals
Whole-exome sequencing identifies genes associated with Tourette’s disorder in multiplex families
The kynurenine pathway in major depressive disorder, bipolar disorder, and schizophrenia: a meta-analysis of 101 studies
Genetic copy number variants, cognition and psychosis: a meta-analysis and a family study
Dissociation of functional and structural plasticity of dendritic spines during NMDAR and mGluR-dependent long-term synaptic depression in wild-type and fragile X model mice
11 0.44
1 0
2 0.09
90 11.13
5 0.37
4 0.03
3 0.91
1 0.03
9 1.89
13 3.55
46 6.12
14 3.88
16 1.07
31 7.93
4 0.21
12 2.91
10 2.74
5 2.12
27 4.58
Earth & Environmental Sciences 141 27.29

Highlight of the month

Astrocyte signalling linked to goal-directed behaviours



Support cells in the brain can affect goal-directed behaviours by interacting with inhibitory nerve cells, a finding that could lead to new treatments for neurological and psychiatric disorders.

Decision making during goal-directed behaviours involves weighing up the costs and benefits of each option. While various regions of the brain are involved in this assessment, the prefrontal provides critical support. The interplay between inhibitory and excitatory neurons in this region is well documented. But how astrocytes, a type of star-shaped supporting cell in the brain, interact with some of these same neurons was poorly understood.

Now, a mouse study led by scientists at the Spanish National Research Council has shown that receptors on astrocytes can sense neurotransmitters released by inhibitory neurons. The astrocytes, in turn, change the electrical firing properties of nearby excitatory neurons in the medial prefrontal cortex, altering brain waves that affect decision making and associated behaviours.

Supported content

  1. Nature Neuroscience 24, 82–92 (2021). doi: 10.1038/s41593-020-00752-x

View the article on the Nature Index

See more research highlights from Spanish National Research Council (CSIC)

More research highlights from Spanish National Research Council (CSIC)

1 June 2020 - 31 May 2021

International vs. domestic collaboration by Share

  • 41.96% Domestic
  • 58.04% International

Note: Hover over the graph to view the percentage of collaboration.

Top 10 domestic collaborators by Share (336 total)

  • Spanish National Research Council (CSIC), Spain
  • Domestic institution
  1. Autonomous University of Madrid (UAM), Spain (69.57)
  2. Institute for Corpuscular Physics (IFIC), Spain (57.86)
  3. University of Valencia (UV), Spain (54.53)
  4. Institute for Theoretical Physics (IFT), Spain (48.52)
  5. University of the Basque Country (UPV/EHU), Spain (39.27)
  6. University of Barcelona (UB), Spain (37.20)
  7. Complutense University of Madrid (UCM), Spain (32.81)
  8. Institute of Health Carlos III (ISCIII), Spain (27.09)
  9. University of Zaragoza (Unizar), Spain (24.89)
  10. Barcelona Institute of Science and Technology (BIST), Spain (24.23)

Note: Collaboration is determined by the fractional count (Share), which is listed in parentheses.

Affiliated joint institutions and consortia

Return to institution outputs