Spanish National Research Council (CSIC)
Consejo Superior de Investigaciones Científicas (CSIC)

Spain

The CSIC (Spanish National Research Council) is the largest and leading public research institution in Spain and the third in Europe due to the quality and quantity of its scientific production. It plays an essential role within the Spanish System for Science, Technology and Innovation and contributes to reinforce Spain’s position at the international level.

CSIC’s main aim is to develop and promote scientific studies to contribute to foster scientific and technological progress. CSIC's mission includes: 1) multidisciplinary scientific and technical research; 2) scientific and technical advice; 3) transferring results to the private sector; 4) contributing to the creation of technology-driven companies; 5) training specialised personnel; 6) management of infrastructure and large facilities; 7) promoting scientific culture. The CSIC is multidisciplinary, carrying out research in almost all fields of knowledge. Its activities encompass basic research all the way through to technological development.

The CSIC is present in all the autonomous regions through their centres across Spain. It comprises 120 centres spread across Spain, and is also present in Brussels and Rome. It is formed by employees with a wide range of academic qualifications and professional categories. The CSIC employs 11,000 people, of which 3.000 are researchers. In total, they represent the 6% of Spain’s R&D workforce and generate approximately the 20% of the country’s production. Likewise, the CSIC collaborates with other juridical entities such as consortia and trading companies.

1 August 2018 - 31 July 2019

Region: Global
Subject/journal group: All

The table to the right includes counts of all research outputs for Spanish National Research Council (CSIC) published between 1 August 2018 - 31 July 2019 which are tracked by the Nature Index.

Hover over the donut graph to view the FC output for each subject. Below, the same research outputs are grouped by subject. Click on the subject to drill-down into a list of articles organized by journal, and then by title.

Note: Articles may be assigned to more than one subject area.

AC FC
1105 182.25

Outputs by subject (FC)

Subject AC FC
Earth & Environmental Sciences 107 21.66
Physical Sciences 564 74.41
Life Sciences 305 50.81
1 0
2 0.94
3 0.11
1 0.02
4 0.26
15 2.79
2 0.32
5 1.24
2 0.45
1 0
15 4.15
Live-cell assays reveal selectivity and sensitivity of the multidrug response in budding yeast
2019-07-11
0.80
Design of reverse transcriptase–specific nucleosides to visualize early steps of HIV-1 replication by click labeling
2019-06-14
0.04
Differential cleavage of lysyl oxidase by the metalloproteinases BMP1 and ADAMTS2/14 regulates collagen binding through a tyrosine sulfate domain
2019-05-31
0.29
Defining α-synuclein species responsible for Parkinson's disease phenotypes in mice
2019-05-29
0.08
The co-chaperone UNC45A is essential for the expression of mitotic kinase NEK7 and tumorigenesis
2019-02-08
0.05
Stabilization of the V2 loop improves the presentation of V2 loop–associated broadly neutralizing antibody epitopes on HIV-1 envelope trimers
2019-02-06
0
Insights into ligand binding by a viral tumor necrosis factor (TNF) decoy receptor yield a selective soluble human type 2 TNF receptor
2019-02-05
0.50
The FtsK-like motor TraB is a DNA-dependent ATPase that forms higher-order assemblies
2019-02-05
0.25
The G2019S variant of leucine-rich repeat kinase 2 (LRRK2) alters endolysosomal trafficking by impairing the function of the GTPase RAB8A
2019-02-01
0.57
Cytochrome c auto-catalyzed carbonylation in the presence of hydrogen peroxide and cardiolipins
2018-12-12
0.05
Characterization of the catalytic flexible loop in the dihydroorotase domain of the human multi-enzymatic protein CAD
2018-10-12
0.30
Plasticity in oligomerization, operator architecture, and DNA binding in the mode of action of a bacterial B12-based photoreceptor
2018-09-27
0.38
Mechanism of action of the viral chemokine binding protein E163 from ectromelia virus
2018-09-26
0.50
Conjugation inhibitors compete with palmitic acid for binding to the conjugative traffic ATPase TrwD, providing a mechanism to inhibit bacterial conjugation
2018-09-10
0.24
A biochemical and genetic discovery pipeline identifies PLCδ4b as a non-receptor activator of heterotrimeric G proteins
2018-09-07
0.11
3 1.07
4 0.26
2 0.32
5 0.76
5 0.79
1 0.22
12 0.59
1 0.03
1 0.33
1 0.04
71 9.66
6 0.09
2 0.06
5 0.26
3 0.41
7 0.38
4 0.82
13 3.19
34 6.14
10 2.02
11 1.04
13 1.52
4 0.24
7 1.97
4 1.82
8 2.47
17 4
Chemistry 243 54.92

Highlight of the month

Alzheimer’s disrupts birth of new brain cells

© Viaframe/Getty

© Viaframe/Getty

Neuroscientists have found evidence that new brain cells are continually being formed in the brain region known as the hippocampus, but that Alzheimer’s disease disrupts this process. This finding could open up new ways to fight memory loss induced by the disease.

The hippocampus, situated squarely in the middle of your grey matter, is mainly associated with memory. Amazingly, it can grow new brain cells in a process called adult hippocampal neurogenesis (AHN).

Recently, researchers at the Spanish National Research Council used improved methods for visualizing immature neurons to show that the hippocampal neurons of healthy human brains are in varying stages of maturation, but that maturation of these cells declined with advancing Alzheimer’s.

Since the inhibition of AHN by Alzheimer’s may be connected with memory retention loss, further research could uncover ways to combat Alzheimer’s inhibition of AHN and thereby curb its destructive effects on memory retention.

Supported content

  1. Nature Medicine 25, 554–560 (2019). doi: 10.1038/s41591-019-0375-9

View the article on the Nature Index

See more research highlights from Spanish National Research Council (CSIC)

More research highlights from Spanish National Research Council (CSIC)

1 August 2018 - 31 July 2019

International vs. domestic collaboration by FC

  • 28.7% Domestic
  • 71.3% International

Note: Hover over the graph to view the percentage of collaboration.

Note: Collaboration is determined by the fractional count (FC), which is listed in parentheses.

Affiliated joint institutions and consortia

Return to institution outputs