University of Tsukuba
筑波大学

Japan

The University of Tsukuba is the anchor institution of Tsukuba Science City — Japan’s premier science-and-technology hub, which is a convenient 45-minute train ride northeast of central Tokyo. The University encompasses 29 national research institutions and more than 200 private sector research institutions. The University operates on the principle that it is open to all.

The University of Tsukuba aims to cross the borders that separate a variety of organizations, such as those between nations, research institutions, and fields of study. The University’s network is expanding globally. In particular, the University has entered into seven campus-in-campus arrangements with universities in six countries and regions, thereby promoting close cooperative relationships between education and research. At present, the University hosts more than 3,000 study abroad students from more than 100 countries and regions of origin.

Collaboration is essential in order to achieve high-quality outcomes with limited resources. As an example, the University is actively engaged in an exchange of talent and joint research that goes beyond the conventional university framework at nationwide joint-use institutes that encompass the four fields of computational science, marine science, plant science, and plasma research.

The joint research being conducted with the research facilities within Tsukuba Science City is expanding into drug development, robotics engineering, space medicine, plant breeding, astrophysics, and sleep science, as well as a wide variety of interdisciplinary areas, leading to a greater number of superior research outcomes than can be achieved on a university scale alone.

The University is also proactively engaging in the support of venture corporations. Thus far, a total of 118 companies have originated from the University of Tsukuba, including Cyberdyne, Inc. All of these companies give back to society through their research outcomes.

A frontrunner in university reform in Japan, the University is creating a flexible education and research structure as well as a university system to meet the needs of the next generation. It aspires to be a comprehensive university, continuously meeting new challenges and developing new areas. The foremost mission of a university is to provide an environment that allows future leaders to realize their full potential. The University of Tsukuba gives students the opportunity develop their individuality and skills through an education that is backed by cutting-edge research.

The University of Tsukuba retains sole responsibility for content. © 2018 The University of Tsukuba.

1 August 2017 - 31 July 2018

Region: Global
Subject/journal group: All

The table to the right includes counts of all research outputs for University of Tsukuba published between 1 August 2017 - 31 July 2018 which are tracked by the Nature Index.

Hover over the donut graph to view the FC output for each subject. Below, the same research outputs are grouped by subject. Click on the subject to drill-down into a list of articles organized by journal, and then by title.

Note: Articles may be assigned to more than one subject area.

AC FC
202 34.59

Outputs by subject (FC)

Subject AC FC
Physical Sciences 120 10.75
Chemistry 36 13.52
Life Sciences 48 9.52
Earth & Environmental Sciences 9 3.50

Highlight of the month

Bowel disease drug shows unexpected mechanism

© Science Photo Library/Getty

© Science Photo Library/Getty

Research from the University of Tsukuba explains how an experimental drug for inflammatory bowel disease works, but it was not in the way that researchers expected. 

E6007 is an experimental therapy being evaluated in Japan for patients with ulcerative colitis. In mouse models of the condition, immune cells stick to the wall of the gut, leading to inflammation. E6007 was thought to block cell adhesion receptors known as integrins — but that outcome turns out to be an indirect effect.

The study authors showed that a molecule very similar to E6007 binds to a particular ‘chaperone’ protein called calreticulin, which interferes the binding of an integrin subunit. Without this interaction, immune cells cannot stick as well to cells along the gut.

The findings offer additional scientific rationale for clinically developing E6007, which is thought to share the same mechanism of action.

Supported content

  1. Nature Communications 9, 1982 (2018). doi: 10.1038/s41467-018-04420-4

View the article on the Nature Index

See more research highlights from University of Tsukuba

More research highlights from University of Tsukuba

1 August 2017 - 31 July 2018

International vs. domestic collaboration by FC

  • 30.32% Domestic
  • 69.68% International

Note: Hover over the graph to view the percentage of collaboration.

Note: Collaboration is determined by the fractional count (FC), which is listed in parentheses.

Affiliated joint institutions and consortia

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