University of Tsukuba
筑波大学

Japan

The University of Tsukuba is located in the suburbs of Tokyo and is at the heart of Tsukuba Science City —Japan’s largest “science city,” which has 29 national research institutes and about 150 private research organizations. The University operates on the principle that it is open to all.

The University of Tsukuba aims to cross the borders that separate a variety of organizations, such as those between nations, research institutions, and fields of study. The University’s network is expanding globally. In particular, the University has entered into ten campus-in-campus arrangements with universities in eight countries and regions, thereby promoting close cooperative relationships between education and research. At present, the University hosts approximately 2,400 study abroad students from more than 110 countries and regions.

Collaboration is essential in order to achieve high-quality outcomes with limited resources. As an example, the University is actively engaged in an exchange of talent and joint research that goes beyond the conventional university framework at nationwide joint-use institutes that encompass the four fields of computational science, marine science, plant science, and plasma research.

The Research and Development Centers are the part of the University’s quest to pursue research and innovation that result in benefits for society. Externally funded, seven centers are newly established as industry-university-government partnerships for joint research in areas of high demand from the community.

The University is also proactively engaging in the support of venture corporations. Thus far, a total of 144 companies have originated from the University of Tsukuba, including Cyberdyne, Inc.

A frontrunner in university reform in Japan, the University is creating a flexible education and research structure as well as a university system to meet the needs of the next generation. It aspires to be a comprehensive university, continuously meeting new challenges and developing new areas. The foremost mission of a university is to provide an environment that allows future leaders to realize their full potential. The University gives students the opportunity to develop their individuality and skills through an education that is backed by cutting-edge research.

The University of Tsukuba retains sole responsibility for content. © 2020 The University of Tsukuba.

1 August 2019 - 31 July 2020

Region: Global
Subject/journal group: All

The table to the right includes counts of all research outputs for University of Tsukuba published between 1 August 2019 - 31 July 2020 which are tracked by the Nature Index.

Hover over the donut graph to view the FC output for each subject. Below, the same research outputs are grouped by subject. Click on the subject to drill-down into a list of articles organized by journal, and then by title.

Note: Articles may be assigned to more than one subject area.

Count Share
240 46.87

Outputs by subject (Share)

Subject Count Share
Chemistry 52 15.07
Physical Sciences 135 17.97
Life Sciences 67 14.89
Earth & Environmental Sciences 14 2.60

Highlight of the month

Cancer-secreted protein shuts down anti-tumour immunity

© JUAN GAERTNER/SCIENCE PHOTO LIBRARY/Getty

© JUAN GAERTNER/SCIENCE PHOTO LIBRARY/Getty

Drugs that target the soluble form of a protein called CD155 could help enhance the anti-tumour activity of the immune system’s natural killer cells.

Researchers from the University of Tsukuba in Japan engineered mouse melanoma cells to produce soluble CD155, a protein expressed by many tumour types.

In its membrane-bound form, CD155 normally interacts with a receptor called DNAM-1 to enhance the anti-cancer activity of various immune cells, including natural killer cells. But in its soluble form, the team showed, CD155 interferes with the usual DNAM-1–mediated ability of natural killer cells to transfer cytotoxic materials into tumour cells.

As a result, the soluble CD155–producing melanoma cells grew more readily in the lungs of mice compared to cancer cells that could not make this protein.

“These are striking results that show how a single protein can drastically change the fate of a tumour,” said senior study author Kazuko Shibuya in a press release.

Supported content

  1. Journal of Experimental Medicine 217, e20191290 (2020). doi: 10.1084/jem.20191290

View the article on the Nature Index

See more research highlights from University of Tsukuba

More research highlights from University of Tsukuba

1 August 2019 - 31 July 2020

International vs. domestic collaboration by Share

  • 42.09% Domestic
  • 57.91% International

Note: Hover over the graph to view the percentage of collaboration.

Top 10 domestic collaborators by Share (158 total)

  • University of Tsukuba, Japan
  • Domestic institution
  1. The University of Tokyo (UTokyo), Japan (17.08)
    6.45
    10.63
  2. National Institute of Advanced Industrial Science and Technology (AIST), Japan (16.30)
    8.03
    8.27
  3. RIKEN, Japan (11.72)
    4.14
    7.58
  4. National Institute for Materials Science (NIMS), Japan (11.63)
    3.13
    8.50
  5. Kyoto University, Japan (7.58)
    3
    4.59
  6. Tohoku University, Japan (6.63)
    3.38
    3.26
  7. Osaka University, Japan (5.05)
    2.15
    2.89
  8. Hokkaido University, Japan (4.05)
    1.99
    2.05
  9. Kyushu University, Japan (3.95)
    2.25
    1.70
  10. Okayama University, Japan (3.86)
    1.18
    2.68

Note: Collaboration is determined by the fractional count (Share), which is listed in parentheses.

Affiliated joint institutions and consortia

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