Tokyo Medical and Dental University (TMDU)


With a history and track record of close coordination between the medical and dental fields as the cornerstone, TMDU contributes to human health and the well-being of society by fostering outstanding healthcare professionals with a humane and global outlook.

Tokyo Medical and Dental University was established as a national medical and dental educational institution on October 12, 1928, and currently located in the Yushima/Shoheizaka area of Tokyo, which is considered sacred ground for scholarship and learning in Japan. Since then, as Japan’s only comprehensive medical university and graduate school, TMDU has provided advanced medical treatment through a fusion of the medical and dental fields and worked to cultivate “professionals with knowledge and humanity,” thereby contributing to human health and the well-being of society. The “knowledge” referenced here includes learning, technology, and self-identity, while “humanity” means culture, sensitivity, and communication ability that accepts diversity. We believe that the fusion of these elements paves the way to becoming a true “professional.”

TMDU comprises the Faculty of Medicine, consisting of the School of Medicine and School of Health Care Sciences; the Faculty of Dentistry, consisting of the School of Dentistry and School of Oral Health Care Sciences; the College of Liberal Arts and Sciences; the Graduate School of Medical and Dental Sciences; the Graduate School of Health Care Sciences; the Institute of Biomaterials and Bioengineering; and the Medical Research Institute. TMDU aims to make wide-ranging contributions to society by training physicians, dentists, nurses, clinical laboratory technicians, dental hygienists, and dental technicians, who combine a desire to heal and a scientific outlook; working to nurture outstanding researchers and medical practitioners; and building research and academic systems in the medical and life science fields.

Medical technology is advancing rapidly, and TMDU, home to the oldest faculty of dentistry and the first school of health care sciences at a Japanese national university, has always been a pioneer in medical and dental education and research. Building on this experience, TMDU has assembled an outstanding faculty, unmatched facilities, and an excellent curriculum in the medical and dental fields, in order to train graduates who can flourish on the world stage through the combination of a broad education, a rich sensibility, high ethical standards, creativity and boldness to make their own decisions, an international outlook, and leadership ability.

The Tokyo Medical and Dental University retains sole responsibility for content. © 2018 Tokyo Medical and Dental University.

1 November 2017 - 31 October 2018

Region: Global
Subject/journal group: All

The table to the right includes counts of all research outputs for Tokyo Medical and Dental University (TMDU) published between 1 November 2017 - 31 October 2018 which are tracked by the Nature Index.

Hover over the donut graph to view the FC output for each subject. Below, the same research outputs are grouped by subject. Click on the subject to drill-down into a list of articles organized by journal, and then by title.

Note: Articles may be assigned to more than one subject area.

54 16.70

Outputs by subject (FC)

Subject AC FC
Life Sciences 43 10.32
Chemistry 10 6.11
Physical Sciences 3 0.53

Highlight of the month

Reverse signalling gives bone growth a boost

© QAI Publishing/Getty

© QAI Publishing/Getty

A well-known bone-removal pathway can operate in reverse to stimulate bone production, a Japan-led team has discovered. This finding could lead to new therapies for osteoporosis and other skeletal disorders.

A group that included scientists from Tokyo Medical and Dental University showed that bone-resorbing cells secrete a kind of membrane-bound packet, called a vesicle, with the RANK receptor on its surface. RANK’s binding partner, RANKL, is normally discharged from bone-forming cells, but the researchers showed that it can also stay on the cell surface, where it binds RANK-bearing vesicles to promote bone formation.

The researchers developed an antibody drug that, because of its dual mechanism of action, could prove more efficacious than other anti-RANKL agents on the market. The novel RANKL-targeted antibody not only inhibited bone resorption, as other drugs do, it also promoted bone growth by activating bone-forming cells with RANKL displayed on their surface.

Supported content

  1. Nature 561, 195–200 (2018). doi: 10.1038/s41586-018-0482-7

View the article on the Nature Index

See more research highlights from Tokyo Medical and Dental University (TMDU)

More research highlights from Tokyo Medical and Dental University (TMDU)

1 November 2017 - 31 October 2018

International vs. domestic collaboration by FC

  • 73.11% Domestic
  • 26.89% International

Note: Hover over the graph to view the percentage of collaboration.

Top 10 domestic collaborators by FC (79 total)

  • Tokyo Medical and Dental University (TMDU), Japan
  • Domestic institution
  1. The University of Tokyo (UTokyo), Japan (10.78)
  2. RIKEN, Japan (5.58)
  3. Kyushu University, Japan (3.29)
  4. Kyoto University, Japan (2.88)
  5. Nagoya University, Japan (1.78)
  6. National Cancer Center (NCC), Japan (1.68)
  7. Keio University, Japan (1.64)
  8. National Institute of Advanced Industrial Science and Technology (AIST), Japan (1.50)
  9. Osaka University, Japan (1.46)
  10. Hiroshima University (HU), Japan (1.40)

Note: Collaboration is determined by the fractional count (FC), which is listed in parentheses.

Affiliated joint institutions and consortia

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