Tokyo Medical and Dental University (TMDU)


With a history and track record of close coordination between the medical and dental fields as the cornerstone, TMDU contributes to human health and the well-being of society by fostering outstanding healthcare professionals with a humane and global outlook.

Tokyo Medical and Dental University was established as a national medical and dental educational institution on October 12, 1928, and currently located in the Yushima/Shoheizaka area of Tokyo, which is considered sacred ground for scholarship and learning in Japan. Since then, as Japan’s only comprehensive medical university and graduate school, TMDU has provided advanced medical treatment through a fusion of the medical and dental fields and worked to cultivate “professionals with knowledge and humanity,” thereby contributing to human health and the well-being of society. The “knowledge” referenced here includes learning, technology, and self-identity, while “humanity” means culture, sensitivity, and communication ability that accepts diversity. We believe that the fusion of these elements paves the way to becoming a true “professional.”

TMDU comprises the Faculty of Medicine, consisting of the School of Medicine and School of Health Care Sciences; the Faculty of Dentistry, consisting of the School of Dentistry and School of Oral Health Care Sciences; the College of Liberal Arts and Sciences; the Graduate School of Medical and Dental Sciences; the Graduate School of Health Care Sciences; the Institute of Biomaterials and Bioengineering; and the Medical Research Institute. TMDU aims to make wide-ranging contributions to society by training physicians, dentists, nurses, clinical laboratory technicians, dental hygienists, and dental technicians, who combine a desire to heal and a scientific outlook; working to nurture outstanding researchers and medical practitioners; and building research and academic systems in the medical and life science fields.

Medical technology is advancing rapidly, and TMDU, home to the oldest faculty of dentistry and the first school of health care sciences at a Japanese national university, has always been a pioneer in medical and dental education and research. Building on this experience, TMDU has assembled an outstanding faculty, unmatched facilities, and an excellent curriculum in the medical and dental fields, in order to train graduates who can flourish on the world stage through the combination of a broad education, a rich sensibility, high ethical standards, creativity and boldness to make their own decisions, an international outlook, and leadership ability.

The Tokyo Medical and Dental University retains sole responsibility for content. © 2018 Tokyo Medical and Dental University.

1 December 2017 - 30 November 2018

Region: Global
Subject/journal group: All

The table to the right includes counts of all research outputs for Tokyo Medical and Dental University (TMDU) published between 1 December 2017 - 30 November 2018 which are tracked by the Nature Index.

Hover over the donut graph to view the FC output for each subject. Below, the same research outputs are grouped by subject. Click on the subject to drill-down into a list of articles organized by journal, and then by title.

Note: Articles may be assigned to more than one subject area.

53 14.76

Outputs by subject (FC)

Subject AC FC
Life Sciences 42 9.15
Chemistry 10 5.33
Physical Sciences 3 0.53

Highlight of the month

Molecular routes to rescuing memory



A protein associated with intellectual disabilities could also be behind the onset of Alzheimer’s disease.

Drugs that destroy the build-up of beta amyloid, or ‘senile plaque’, in Alzheimer’s patients have yet to improve memory and brain function.

A team led by researchers from Tokyo Medical and Dental University has found that, just before the growth of senile plaque in mice developing Alzheimer’s, the protein SRRM2 underwent chemical changes that reduced levels of PQBP1, a protein linked to intellectual disabilities.

The team bred mice with a mutated PQBP1 gene, which modified synapse structures in the mice’s brains and disrupted communication between neurons. Supplementing Alzheimer’s mice with PQBP1 proteins recovered the synapse structure and improved their brain function.

Uncovering the molecules and mutations that precede the onset of Alzheimer’s could lead to targeted gene therapies.

Supported content

  1. Molecular Psychiatry 23, 2090–2110 (2018). doi: 10.1038/s41380-018-0253-8

View the article on the Nature Index

See more research highlights from Tokyo Medical and Dental University (TMDU)

More research highlights from Tokyo Medical and Dental University (TMDU)

1 December 2017 - 30 November 2018

International vs. domestic collaboration by FC

  • 72.11% Domestic
  • 27.89% International

Note: Hover over the graph to view the percentage of collaboration.

Top 10 domestic collaborators by FC (80 total)

  • Tokyo Medical and Dental University (TMDU), Japan
  • Domestic institution
  1. The University of Tokyo (UTokyo), Japan (10)
  2. RIKEN, Japan (5.71)
  3. Kyoto University, Japan (3.32)
  4. Kyushu University, Japan (1.76)
  5. Hiroshima University (HU), Japan (1.69)
  6. National Cancer Center (NCC), Japan (1.68)
  7. Keio University, Japan (1.64)
  8. Juntendo University, Japan (1.33)
  9. National Center for Neurology and Psychiatry (NCNP), Japan (1.32)
  10. Nagoya University, Japan (1.25)

Note: Collaboration is determined by the fractional count (FC), which is listed in parentheses.

Affiliated joint institutions and consortia

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