University College Cork (UCC)

Ireland

University College Cork (UCC) is a collegiate, progressive and dynamic university in the heart of Cork city in the south of Ireland.

Founded in 1845, UCC boasts a vibrant, modern, environmentally sustainable campus and a top-ranked student experience. We have a proud tradition of independent thinking, significant achievements and strong academic and professional leadership.

UCC is also Ireland’s first five-star University with internationally-recognised research in science, food, engineering, medicine, business, law, social sciences and the humanities.

Ranked in the top 2% of universities worldwide based on the quality of our research outputs and peer esteem indicators, UCC is an internationally competitive, globally-focused, research-led university that is focussed on creating and supporting world-leading clusters of researchers, building on the research strengths of the institution — but don’t take our word for it:

UCC is the top ranked institution in Ireland, 16th in Europe and 52nd worldwide, based on top 1% of research publications, CWTS Leiden Ranking 2015
UCC is the top performing university internationally, based on obtaining the highest number of ‘A’ scores — 21 out of 28, EU U-Multirank Exercise 2015
UCC is the world’s leading ‘green’ university — the first in the world to be awarded the esteemed ‘Green Flag’ by the Federation for Environmental Education, Copenhagen and the 2nd in the world in the Greenmetric World University Ranking Exercise 2015
UCC is the Irish University of the Year for 2016, Sunday Times Good University Guide

To discover more about UCC and our research ambitions, please visit ucc.ie/en/research.

1 August 2017 - 31 July 2018

Region: Global
Subject/journal group: All

The table to the right includes counts of all research outputs for University College Cork (UCC) published between 1 August 2017 - 31 July 2018 which are tracked by the Nature Index.

Hover over the donut graph to view the FC output for each subject. Below, the same research outputs are grouped by subject. Click on the subject to drill-down into a list of articles organized by journal, and then by title.

Note: Articles may be assigned to more than one subject area.

AC	FC
56	10.77

Outputs by subject (FC)

Subject	AC	FC
Physical Sciences	27	3.52
Life Sciences	19	6.01
Cell Host & Microbe	1	1
Current Biology	2	0.17
Journal of Biological Chemistry	2	1.47
Molecular Cell	2	0.51
Molecular Psychiatry	1	0
Nature	1	0.81
Nature Communications	4	0.70
Proceedings of the National Academy of Sciences of the United States of America	1	0.06
Science	2	0.01
Science Advances	1	0.09
The ISME Journal: Multidisciplinary Journal of Microbial Ecology	1	0.18
eLife	1	1
Chemistry	19	1.70
Earth & Environmental Sciences	5	1.08

Highlight of the month

All queued up for metabolite regulation

Metabolites known as polyamines regulate levels of their own biosynthetic enzymes by creating traffic jams of ribosomes — the organelles responsible for producing proteins.

A team, including scientists from University College Cork, showed that this ribosomal bottleneck can occur along the gene transcript that encodes AZIN1, an enzyme that indirectly promotes the production of polyamines. This ‘queue’ of stalled ribosome then prompts the backed-up organelles to make a different protein at an upstream start signal. Consequently, the cell machinery produces less AZIN1, helping to reduce polyamine levels.

The researchers propose that this auto-regulation mechanism involving ribosome queuing could be widespread, affecting many crucial cellular processes. Furthermore, since polyamine metabolism is often dysregulated in cancer, the findings could help expose new therapeutic targets for drug development.

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