The University of South Australia (UniSA)

Australia

In 2016, the University of South Australia (UniSA) celebrates its 25th birthday. We are a young university, continuing to set the pace for world-class research and solutions for a changing world. As Australia’s University of Enterprise, the spirit of enterprise runs through everything we do.

Our research is inspired by challenges and opportunities, partnered with end-users and communities, and underpinned by excellence. We work collaboratively with our partners right from the conception of a research idea, allowing our research directions to be shaped by their opportunities and challenges.

UniSA’s strong commitment to cutting-edge research and engagement with industry has been well recognised, with 97 per cent of our research rated at or above world-class standard (Excellence for Research in Australia 2015). This is an impressive result for a young university, and we are proud of our achievements.

Our research culture is vibrant, outward facing and responsive. We pride ourselves on our capacity to create interdisciplinary teams that can tackle significant real-world challenges, and our researchers strive to make a difference outside the world of academe.

We are globally connected and engaged, helping solve the problems of industry and the professions. Our teaching is industry-informed, our research inventive and adventurous, and focused on creating impact. Through our research, we create knowledge that is central to global economic and social prosperity.

University of South Australia retains sole responsibility for content © 2016 University of South Australia.

1 April 2017 - 31 March 2018

Region: Global
Subject/journal group: All

The table to the right includes counts of all research outputs for The University of South Australia (UniSA) published between 1 April 2017 - 31 March 2018 which are tracked by the Nature Index.

Hover over the donut graph to view the FC output for each subject. Below, the same research outputs are grouped by subject. Click on the subject to drill-down into a list of articles organized by journal, and then by title.

Note: Articles may be assigned to more than one subject area.

AC FC
53 7.37

Outputs by subject (FC)

Subject AC FC
Physical Sciences 16 1.27
Chemistry 13 3.13
Earth & Environmental Sciences 12 2.27
Life Sciences 20 1.55

Highlight of the month

New leukaemia target identified

© theasis/Getty

© theasis/Getty

New research has clarified the operation of the receptor for interleukin-3, an immune signalling molecule implicated in leukaemia and a promising target for cancer therapy.

A team from several Australian institutes, including the University of South Australia, determined the structure of the interleukin-3 receptor with and without interleukin-3 bound to it.

How the receptor binds interleukin-3 has remained elusive. Structural studies of the receptor alone have implicated a region known as the N-terminal domain (NTD), which is also thought to be highly mobile since it has been observed in two shapes, or conformations.

The new structures showed that NTD is crucial for binding and that the bound conformation is intermediate between the two previously observed forms. When the researchers used a mutated form of interleukin-3 that binds more strongly to the receptor, they found that the mobility of NTD was reduced — it was pulled into one conformation, which had enhanced interleukin-3 recognition. Understanding the dynamics on interleukin recognition by its receptor presents the opportunity to develop new therapies targeting this process.

Supported content

  1. Nature Communications 9, 386 (2018). doi: 10.1038/s41467-017-02633-7

View the article on the Nature Index

See more research highlights from The University of South Australia (UniSA)

More research highlights from The University of South Australia (UniSA)

1 April 2017 - 31 March 2018

International vs. domestic collaboration by FC

  • 63.55% Domestic
  • 36.45% International

Note: Hover over the graph to view the percentage of collaboration.

Note: Collaboration is determined by the fractional count (FC), which is listed in parentheses.

Affiliated joint institutions and consortia

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