United States of America (USA)

1 December 2019 - 30 November 2020

Subject/journal group: All

The table to the right includes counts of all research outputs for United States of America (USA) published between 1 December 2019 - 30 November 2020 which are tracked by the Nature Index.

Hover over the donut graph to view the FC output for each subject. Below, the same research outputs are grouped by subject. Click on the subject to drill-down into a list of articles organized by journal, and then by title.

Note: Articles may be assigned to more than one subject area.

Count Share
28986 20575.61

Outputs by subject (FC)

Subject Count Share
Life Sciences 12951 9608.83
113 68.86
92 74.32
263 209.84
286 222.26
98 73.98
93 64.78
102 81.37
1 1
290 206.53
119 97.31
70 44.50
1 0.44
72 61.25
98 69.18
88 68.97
789 660.54
139 109.68
370 282.30
123 83.23
416 350.22
180 140.73
162 112.95
477 328.90
99 78.77
72 51.49
109 84.90
2186 1421.72
92 55.28
1 0.83
78 51.61
153 105.50
Dysregulated ribonucleoprotein granules promote cardiomyopathy in RBM20 gene-edited pigs
2020-11-13
0.93
Rapid pathogen detection by metagenomic next-generation sequencing of infected body fluids
2020-11-09
0.95
Using common genetic variation to examine phenotypic expression and risk prediction in 22q11.2 deletion syndrome
2020-11-09
0.31
Maturation of the gut microbiome during the first year of life contributes to the protective farm effect on childhood asthma
2020-11-02
0.10
Wearable sensor data and self-reported symptoms for COVID-19 detection
2020-10-29
1
Increased circulation time of Plasmodium falciparum underlies persistent asymptomatic infection in the dry season
2020-10-26
0.30
Precision medicine treatment in acute myeloid leukemia using prospective genomic profiling: feasibility and preliminary efficacy of the Beat AML Master Trial
2020-10-26
1
Modeling COVID-19 scenarios for the United States
2020-10-23
0.94
A global survey of potential acceptance of a COVID-19 vaccine
2020-10-20
0.63
Exome sequencing implicates genetic disruption of prenatal neuro-gliogenesis in sporadic congenital hydrocephalus
2020-10-19
0.87
Midkine rewires the melanoma microenvironment toward a tolerogenic and immune-resistant state
2020-10-19
0.08
Magnitude, demographics and dynamics of the effect of the first wave of the COVID-19 pandemic on all-cause mortality in 21 industrialized countries
2020-10-14
0.11
Anti-GD2 CAR-NKT cells in patients with relapsed or refractory neuroblastoma: an interim analysis
2020-10-12
1
Neoadjuvant PD-L1 plus CTLA-4 blockade in patients with cisplatin-ineligible operable high-risk urothelial carcinoma
2020-10-12
1
Bispecific anti-CD20, anti-CD19 CAR T cells for relapsed B cell malignancies: a phase 1 dose escalation and expansion trial
2020-10-05
1
Characteristics of anti-CD19 CAR T cell infusion products associated with efficacy and toxicity in patients with large B cell lymphomas
2020-10-05
1
Clinical utility of circulating tumor DNA sequencing in advanced gastrointestinal cancer: SCRUM-Japan GI-SCREEN and GOZILA studies
2020-10-05
0.03
Combined PD-1, BRAF and MEK inhibition in advanced BRAF-mutant melanoma: safety run-in and biomarker cohorts of COMBI-i
2020-10-05
0.33
Continuous versus intermittent BRAF and MEK inhibition in patients with BRAF-mutated melanoma: a randomized phase 2 trial
2020-10-05
1
Crowding and the shape of COVID-19 epidemics
2020-10-05
0.60
Global maps of travel time to healthcare facilities
2020-09-28
0.31
Neuronal defects in a human cellular model of 22q11.2 deletion syndrome
2020-09-28
0.98
Convalescent plasma treatment of severe COVID-19: a propensity score–matched control study
2020-09-15
1
Production, safety and efficacy of iPSC-derived mesenchymal stromal cells in acute steroid-resistant graft versus host disease: a phase I, multicenter, open-label, dose-escalation study
2020-09-14
0.38
Single-cell transcriptomic atlas of the human endometrium during the menstrual cycle
2020-09-14
0.70
Insulin dose optimization using an automated artificial intelligence-based decision support system in youths with type 1 diabetes
2020-09-09
0.54
Avelumab plus axitinib versus sunitinib in advanced renal cell carcinoma: biomarker analysis of the phase 3 JAVELIN Renal 101 trial
2020-09-07
0.57
Polygenic architecture informs potential vulnerability to drug-induced liver injury
2020-09-07
0.24
Ad26 vaccine protects against SARS-CoV-2 severe clinical disease in hamsters
2020-09-03
0.91
Dual CD4-based CAR T cells with distinct costimulatory domains mitigate HIV pathogenesis in vivo
2020-08-31
1
An inflammatory cytokine signature predicts COVID-19 severity and survival
2020-08-24
0.97
A digital biomarker of diabetes from smartphone-based vascular signals
2020-08-17
1
Articular cartilage regeneration by activated skeletal stem cells
2020-08-17
0.94
A multidimensional precision medicine approach identifies an autism subtype characterized by dyslipidemia
2020-08-10
0.93
A peripheral immune signature of responsiveness to PD-1 blockade in patients with classical Hodgkin lymphoma
2020-08-10
1
The role of exome sequencing in newborn screening for inborn errors of metabolism
2020-08-10
0.90
A combined risk score enhances prediction of type 1 diabetes among susceptible children
2020-08-07
0.57
The potential public health consequences of COVID-19 on malaria in Africa
2020-08-07
0.02
Using a real-world network to model localized COVID-19 control strategies
2020-08-07
0.02
Emergence and clonal expansion of in vitro artemisinin-resistant R561H mutant parasites in Rwanda
2020-08-03
0.14
Immune complement and coagulation dysfunction in adverse outcomes of SARS-CoV-2 infection
2020-08-03
1
Implications of TP53 allelic state for genome stability, clinical presentation and outcomes in myelodysplastic syndromes
2020-08-03
0.32
Single-cell atlas of colonic CD8+ T cells in ulcerative colitis
2020-08-03
0.05
Assessment of cognitive and neural recovery in survivors of pediatric brain tumors in a pilot clinical trial using metformin
2020-07-27
0.13
Population genetic screening efficiently identifies carriers of autosomal dominant diseases
2020-07-27
1
Therapeutic efficacy of antisense oligonucleotides in mouse models of CLN3 Batten disease
2020-07-27
1
A stochastic agent-based model of the SARS-CoV-2 epidemic in France
2020-07-14
0.25
Antibody-mediated inhibition of GDF15–GFRAL activity reverses cancer cachexia in mice
2020-07-13
1
Myocardial infarction accelerates breast cancer via innate immune reprogramming
2020-07-13
0.96
Xenogeneic cross-circulation for extracorporeal recovery of injured human lungs
2020-07-13
1
Rapid isolation and profiling of a diverse panel of human monoclonal antibodies targeting the SARS-CoV-2 spike protein
2020-07-10
0.97
Population-based surveys of antibodies against SARS-CoV-2 in Southern Brazil
2020-07-08
0.05
A validated predictive algorithm of post-traumatic stress course following emergency department admission after a traumatic stressor
2020-07-06
1
Bacterial and host determinants of cough aerosol culture positivity in patients with drug-resistant versus drug-susceptible tuberculosis
2020-06-29
0.13
Pre-existing immunity to influenza virus hemagglutinin stalk might drive selection for antibody-escape mutant viruses in a human challenge model
2020-06-29
1
Determinants of COVID-19 disease severity in patients with cancer
2020-06-24
1
A single-cell landscape of high-grade serous ovarian cancer
2020-06-22
0.91
Detection and discrimination of intracranial tumors using plasma cell-free DNA methylomes
2020-06-22
0.13
Detection of renal cell carcinoma using plasma and urine cell-free DNA methylomes
2020-06-22
0.80
Human–computer collaboration for skin cancer recognition
2020-06-22
0.13
Tau molecular diversity contributes to clinical heterogeneity in Alzheimer’s disease
2020-06-22
1
Disease and healthcare burden of COVID-19 in the United States
2020-06-16
1
Human postprandial responses to food and potential for precision nutrition
2020-06-11
0.22
A single-cell atlas of the peripheral immune response in patients with severe COVID-19
2020-06-08
1
Cartography of opportunistic pathogens and antibiotic resistance genes in a tertiary hospital environment
2020-06-08
0.32
Reconstruction of the human blood–brain barrier in vitro reveals a pathogenic mechanism of APOE4 in pericytes
2020-06-08
1
Genome-wide cell-free DNA mutational integration enables ultra-sensitive cancer monitoring
2020-06-01
1
IgG-cleaving endopeptidase enables in vivo gene therapy in the presence of anti-AAV neutralizing antibodies
2020-06-01
0.48
Single-arm, open-label phase 2 trial of pembrolizumab in patients with leptomeningeal carcinomatosis
2020-06-01
1
Interplay of somatic alterations and immune infiltration modulates response to PD-1 blockade in advanced clear cell renal cell carcinoma
2020-05-29
1
Geospatial immune variability illuminates differential evolution of lung adenocarcinoma
2020-05-27
0
The effect of LRRK2 loss-of-function variants in humans
2020-05-27
0.69
BL-8040, a CXCR4 antagonist, in combination with pembrolizumab and chemotherapy for pancreatic cancer: the COMBAT trial
2020-05-25
0.35
Common germline variants of the human APOE gene modulate melanoma progression and survival
2020-05-25
1
Systemic dysfunction and plasticity of the immune macroenvironment in cancer models
2020-05-25
0.90
Artificial intelligence–enabled rapid diagnosis of patients with COVID-19
2020-05-19
0.64
A deep learning system for differential diagnosis of skin diseases
2020-05-18
0.95
A serological assay to detect SARS-CoV-2 seroconversion in humans
2020-05-12
0.82
A single-cell and single-nucleus RNA-Seq toolbox for fresh and frozen human tumors
2020-05-11
1
Development and validation of serological markers for detecting recent Plasmodium vivax infection
2020-05-11
0.04
Elevated serum interleukin-8 is associated with enhanced intratumor neutrophils and reduced clinical benefit of immune-checkpoint inhibitors
2020-05-11
0.87
High systemic and tumor-associated IL-8 correlates with reduced clinical benefit of PD-L1 blockade
2020-05-11
0.88
Prediction of mortality from 12-lead electrocardiogram voltage data using a deep neural network
2020-05-11
1
Real-time tracking of self-reported symptoms to predict potential COVID-19
2020-05-11
0.15
T cell-inducing vaccine durably prevents mucosal SHIV infection even with lower neutralizing antibody titers
2020-05-11
0.97
Modeling shield immunity to reduce COVID-19 epidemic spread
2020-05-07
0.92
Age and generational patterns of overdose death risk from opioids and other drugs
2020-05-04
0.90
Locoregional delivery of CAR T cells to the cerebrospinal fluid for treatment of metastatic medulloblastoma and ependymoma
2020-04-27
0.21
Locoregionally administered B7-H3-targeted CAR T cells for treatment of atypical teratoid/rhabdoid tumors
2020-04-27
0.53
Safety and feasibility of CRISPR-edited T cells in patients with refractory non-small-cell lung cancer
2020-04-27
0.03
Clinical and virologic characteristics of the first 12 patients with coronavirus disease 2019 (COVID-19) in the United States
2020-04-23
1
SARS-CoV-2 entry factors are highly expressed in nasal epithelial cells together with innate immune genes
2020-04-23
0.43
Mapping local patterns of childhood overweight and wasting in low- and middle-income countries between 2000 and 2017
2020-04-20
0.09
Adaptive evolution of virulence and persistence in carbapenem-resistant
2020-04-13
1
Large-scale proteomic analysis of Alzheimer’s disease brain and cerebrospinal fluid reveals early changes in energy metabolism associated with microglia and astrocyte activation
2020-04-13
1
Multimodel preclinical platform predicts clinical response of melanoma to immunotherapy
2020-04-13
1
Polygenic and clinical risk scores and their impact on age at onset and prediction of cardiometabolic diseases and common cancers
2020-04-07
0.39
Respiratory virus shedding in exhaled breath and efficacy of face masks
2020-04-03
0.14
A randomized proof-of-mechanism trial applying the ‘fast-fail’ approach to evaluating κ-opioid antagonism as a treatment for anhedonia
2020-03-30
0.98
Effects of underfeeding and oral vancomycin on gut microbiome and nutrient absorption in humans
2020-03-23
0.85
Integrated single-cell analysis of multicellular immune dynamics during hyperacute HIV-1 infection
2020-03-23
0.69
Safety and immunogenicity of Ad26 and MVA vaccines in acutely treated HIV and effect on viral rebound after antiretroviral therapy interruption
2020-03-23
0.52
Trans-biobank analysis with 676,000 individuals elucidates the association of polygenic risk scores of complex traits with human lifespan
2020-03-23
0.20
Estimating clinical severity of COVID-19 from the transmission dynamics in Wuhan, China
2020-03-19
0.56
CTLA-4 and PD-1 dual blockade induces SIV reactivation without control of rebound after antiretroviral therapy interruption
2020-03-16
0.97
Therapeutic base editing of human hematopoietic stem cells
2020-03-16
0.97
Characteristics of pediatric SARS-CoV-2 infection and potential evidence for persistent fecal viral shedding
2020-03-13
0.04
A soluble phosphorylated tau signature links tau, amyloid and the evolution of stages of dominantly inherited Alzheimer’s disease
2020-03-11
0.63
Multiplexed single-cell morphometry for hematopathology diagnostics
2020-03-11
1
Skin-interfaced biosensors for advanced wireless physiological monitoring in neonatal and pediatric intensive-care units
2020-03-11
0.95
Deep learning models for electrocardiograms are susceptible to adversarial attack
2020-03-09
1
Early prediction of circulatory failure in the intensive care unit using machine learning
2020-03-09
0.06
STAR particles for enhanced topical drug and vaccine delivery
2020-03-09
1
Diagnostic value of plasma phosphorylated tau181 in Alzheimer’s disease and frontotemporal lobar degeneration
2020-03-02
0.88
Plasma P-tau181 in Alzheimer’s disease: relationship to other biomarkers, differential diagnosis, neuropathology and longitudinal progression to Alzheimer’s dementia
2020-03-02
0.40
Broad immune activation underlies shared set point signatures for vaccine responsiveness in healthy individuals and disease activity in patients with lupus
2020-02-24
0.96
Initial results from a first-in-human gene therapy trial on X-linked retinitis pigmentosa caused by mutations in RPGR
2020-02-24
0.22
TMEM30A loss-of-function mutations drive lymphomagenesis and confer therapeutically exploitable vulnerability in B-cell lymphoma
2020-02-24
0.04
Viable bacterial colonization is highly limited in the human intestine in utero
2020-02-24
1
An immune-cell signature of bacterial sepsis
2020-02-17
1
Dynamic imaging in patients with tuberculosis reveals heterogeneous drug exposures in pulmonary lesions
2020-02-17
1
Effect of salt substitution on community-wide blood pressure and hypertension incidence
2020-02-17
0.20
Engineered immunogen binding to alum adjuvant enhances humoral immunity
2020-02-17
1
Interleukin-22-mediated host glycosylation prevents Clostridioides difficile infection by modulating the metabolic activity of the gut microbiota
2020-02-17
0.65
Cancer prognosis with shallow tumor RNA sequencing
2020-02-10
1
Regenerative lineages and immune-mediated pruning in lung cancer metastasis
2020-02-10
1
The Angiosarcoma Project: enabling genomic and clinical discoveries in a rare cancer through patient-partnered research
2020-02-10
1
Using human genetics to understand the disease impacts of testosterone in men and women
2020-02-10
0.01
Combination anti-HIV-1 antibody therapy is associated with increased virus-specific T cell immunity
2020-02-03
0.64
Potent Zika and dengue cross-neutralizing antibodies induced by Zika vaccination in a dengue-experienced donor
2020-02-03
1
Lentiviral gene therapy for X-linked chronic granulomatous disease
2020-01-27
0.42
iPSC modeling of young-onset Parkinson’s disease reveals a molecular signature of disease and novel therapeutic candidates
2020-01-27
1
A human ciliopathy reveals essential functions for NEK10 in airway mucociliary clearance
2020-01-20
0.76
Fecal dysbiosis in infants with cystic fibrosis is associated with early linear growth failure
2020-01-20
0.97
Safety and feasibility of anti-CD19 CAR T cells with fully human binding domains in patients with B-cell lymphoma
2020-01-20
1
Targeted therapy guided by single-cell transcriptomic analysis in drug-induced hypersensitivity syndrome: a case report
2020-01-20
1
Anomalously warm temperatures are associated with increased injury deaths
2020-01-13
0.21
Antitumor activity of crizotinib in lung cancers harboring a exon 14 alteration
2020-01-13
0.76
Association of lead-exposure risk and family income with childhood brain outcomes
2020-01-13
0.83
Human and mouse single-nucleus transcriptomics reveal TREM2-dependent and TREM2-independent cellular responses in Alzheimer’s disease
2020-01-13
0.76
Personal aging markers and ageotypes revealed by deep longitudinal profiling
2020-01-13
1
Phenome-based approach identifies -linked Mendelian syndrome through zebrafish models, biobank associations and clinical studies
2020-01-13
0.67
High-resolution mycobiota analysis reveals dynamic intestinal translocation preceding invasive candidiasis
2020-01-06
0.86
Near real-time intraoperative brain tumor diagnosis using stimulated Raman histology and deep neural networks
2020-01-06
1
Autism risk in offspring can be assessed through quantification of male sperm mosaicism
2019-12-23
0.83
Immune profiling of human tumors identifies CD73 as a combinatorial target in glioblastoma
2019-12-23
0.95
Spinal subpial delivery of AAV9 enables widespread gene silencing and blocks motoneuron degeneration in ALS
2019-12-23
0.72
Human SNORA31 variations impair cortical neuron-intrinsic immunity to HSV-1 and underlie herpes simplex encephalitis
2019-12-05
0.52
Undulating changes in human plasma proteome profiles across the lifespan
2019-12-05
0.85
A selective BCL-X PROTAC degrader achieves safe and potent antitumor activity
2019-12-02
1
Integrative molecular and clinical modeling of clinical outcomes to PD1 blockade in patients with metastatic melanoma
2019-12-02
0.44
Plasma protein patterns as comprehensive indicators of health
2019-12-02
0.71
Prospective virome analyses in young children at increased genetic risk for type 1 diabetes
2019-12-02
0.79
74 60.03
108 85.85
81 64.61
213 182.14
156 106.03
284 216.28
1922 1480.98
265 182.56
328 233.82
699 499.53
217 169.33
99 47.48
118 85.79
71 40.81
1084 890.33
Earth & Environmental Sciences 4341 2853.57
Chemistry 7235 5250.77
Physical Sciences 8259 5364.59

1 December 2019 - 30 November 2020

View the connected world of international research collaboration. Visualize collaborations by subject or region.

Collaborations between countries

Percentage of collaboration by Share

Hover over the graph to view the percentage of collaboration.

Top 10 collaborators by Share

  • United States of America (USA)
  1. China (4420.77)
    2106.75
    2314.03
  2. 1144.34
    831.17
  3. Germany (1914.97)
    1082.34
    832.63
  4. Canada (1205.80)
    753.10
    452.71
  5. France (1078.91)
    656.65
    422.26
  6. Japan (974.94)
    598.68
    376.26
  7. Australia (712.66)
    427.56
    285.10
  8. Switzerland (698.47)
    414.10
    284.37
  9. South Korea (697.43)
    420.77
    276.66
  10. Italy (582.81)
    354.79
    228.01

Collaboration is determined by the combined fractional count (Share) of United States of America (USA) and the collaborating country.

Top 10 institutions from United States of America (USA)

Institution Count Share
1. Harvard University 2535 914
2. Stanford University 1694 647.18
3. Massachusetts Institute of Technology (MIT) 1828 528.46
4. National Institutes of Health (NIH) 1085 404.29
5. University of California, Berkeley (UC Berkeley) 1297 395.84
6. University of Michigan (U-M) 1010 391.33
7. Yale University 987 350.79
8. University of California, San Diego (UC San Diego) 1003 342.66
9. Columbia University in the City of New York (CU) 1027 327.89
10. University of California, Los Angeles (UCLA) 1114 327.29

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