United States of America (USA)

1 December 2019 - 30 November 2020

Subject/journal group: All

The table to the right includes counts of all research outputs for United States of America (USA) published between 1 December 2019 - 30 November 2020 which are tracked by the Nature Index.

Hover over the donut graph to view the FC output for each subject. Below, the same research outputs are grouped by subject. Click on the subject to drill-down into a list of articles organized by journal, and then by title.

Note: Articles may be assigned to more than one subject area.

Count Share
28986 20575.61

Outputs by subject (FC)

Subject Count Share
Life Sciences 12951 9608.83
113 68.86
92 74.32
263 209.84
286 222.26
98 73.98
93 64.78
102 81.37
1 1
290 206.53
119 97.31
70 44.50
1 0.44
72 61.25
98 69.18
88 68.97
789 660.54
139 109.68
370 282.30
123 83.23
416 350.22
180 140.73
162 112.95
477 328.90
99 78.77
72 51.49
109 84.90
2186 1421.72
A clinically applicable deep-learning model for detecting intracranial aneurysm in computed tomography angiography images
2020-11-30
0.13
An investigation of irreproducibility in maximum likelihood phylogenetic inference
2020-11-30
0.60
Bedaquiline reprograms central metabolism to reveal glycolytic vulnerability in Mycobacterium tuberculosis
2020-11-30
0.37
Chronic neuronal activation increases dynamic microtubules to enhance functional axon regeneration after dorsal root crush injury
2020-11-30
1
Development of a multi-antigenic SARS-CoV-2 vaccine candidate using a synthetic poxvirus platform
2020-11-30
1
Direct binding of TFEα opens DNA binding cleft of RNA polymerase
2020-11-30
0.33
Epigenome-wide meta-analysis of DNA methylation differences in prefrontal cortex implicates the immune processes in Alzheimer’s disease
2020-11-30
1
Essential omega-3 fatty acids tune microglial phagocytosis of synaptic elements in the mouse developing brain
2020-11-30
0.08
Identification of regulators of poly-ADP-ribose polymerase inhibitor response through complementary CRISPR knockout and activation screens
2020-11-30
1
Identity-by-descent detection across 487,409 British samples reveals fine scale population structure and ultra-rare variant associations
2020-11-30
0.29
Lethality of SARS-CoV-2 infection in K18 human angiotensin-converting enzyme 2 transgenic mice
2020-11-30
1
Light-driven formation of manganese oxide by today’s photosystem II supports evolutionarily ancient manganese-oxidizing photosynthesis
2020-11-30
0.09
Location-specific inhibition of Akt reveals regulation of mTORC1 activity in the nucleus
2020-11-30
1
MINPP1 prevents intracellular accumulation of the chelator inositol hexakisphosphate and is mutated in Pontocerebellar Hypoplasia
2020-11-30
0.10
Organo–organic and organo–mineral interfaces in soil at the nanometer scale
2020-11-30
0.95
Perceptually unidentifiable stimuli influence cortical processing and behavioral performance
2020-11-30
1
Single cell RNA sequencing of human microglia uncovers a subset associated with Alzheimer’s disease
2020-11-30
0.87
A grass-specific cellulose–xylan interaction dominates in sorghum secondary cell walls
2020-11-27
0.93
A multivariable Mendelian randomization analysis investigating smoking and alcohol consumption in oral and oropharyngeal cancer
2020-11-27
0.12
A systematic comprehensive longitudinal evaluation of dietary factors associated with acute myocardial infarction and fatal coronary heart disease
2020-11-27
0.94
CRISPR based editing of SIV proviral DNA in ART treated non-human primates
2020-11-27
1
Catalysis of proline isomerization and molecular chaperone activity in a tug-of-war
2020-11-27
0.25
Cellular events of acute, resolving or progressive COVID-19 in SARS-CoV-2 infected non-human primates
2020-11-27
1
Comprehensive prediction of secondary metabolite structure and biological activity from microbial genome sequences
2020-11-27
0.02
Feedback regulation of crystal growth by buffering monomer concentration
2020-11-27
1
Feedforward prediction error signals during episodic memory retrieval
2020-11-27
1
In vitro-transcribed antigen receptor mRNA nanocarriers for transient expression in circulating T cells in vivo
2020-11-27
1
Mechanism and inhibition of Streptococcus pneumoniae IgA1 protease
2020-11-27
0.78
MiCas9 increases large size gene knock-in rates and reduces undesirable on-target and off-target indel edits
2020-11-27
1
Nutrients cause grassland biomass to outpace herbivory
2020-11-27
0.30
Pan-cancer analysis demonstrates that integrating polygenic risk scores with modifiable risk factors improves risk prediction
2020-11-27
0.75
Plasma N-terminal tau fragment levels predict future cognitive decline and neurodegeneration in healthy elderly individuals
2020-11-27
1
Robustness and lethality in multilayer biological molecular networks
2020-11-27
0.75
Survival of the weakest in non-transitive asymmetric interactions among strains of E. coli
2020-11-27
1
The structural basis of promiscuity in small multidrug resistance transporters
2020-11-27
1
Trans- and cis-acting effects of Firre on epigenetic features of the inactive X chromosome
2020-11-27
1
Transcription-dependent cohesin repositioning rewires chromatin loops in cellular senescence
2020-11-27
0.04
Tumor evolutionary trajectories during the acquisition of invasiveness in early stage lung adenocarcinoma
2020-11-27
0.16
Tumor microenvironment-targeted nanoparticles loaded with bortezomib and ROCK inhibitor improve efficacy in multiple myeloma
2020-11-27
0.98
Ubiquitous selection for mecA in community-associated MRSA across diverse chemical environments
2020-11-27
0.11
Yeast Nup84-Nup133 complex structure details flexibility and reveals conservation of the membrane anchoring ALPS motif
2020-11-27
1
β-Pix-dependent cellular protrusions propel collective mesoderm migration in the mouse embryo
2020-11-27
1
A deep learning diagnostic platform for diffuse large B-cell lymphoma with high accuracy across multiple hospitals
2020-11-26
0.38
A stem cell reporter based platform to identify and target drug resistant stem cells in myeloid leukemia
2020-11-26
1
Direct RNA sequencing reveals m6A modifications on adenovirus RNA are necessary for efficient splicing
2020-11-26
1
Distinct prefrontal top-down circuits differentially modulate sensorimotor behavior
2020-11-26
1
High-speed volumetric two-photon fluorescence imaging of neurovascular dynamics
2020-11-26
1
Infants recruit logic to learn about the social world
2020-11-26
0.33
Rapid de novo evolution of lysis genes in single-stranded RNA phages
2020-11-26
1
SARS-CoV-2 spike-protein D614G mutation increases virion spike density and infectivity
2020-11-26
0.93
Training confounder-free deep learning models for medical applications
2020-11-26
1
Vitamin D metabolites and the gut microbiome in older men
2020-11-26
0.67
Biased localization of actin binding proteins by actin filament conformation
2020-11-25
0.83
Designed CXCR4 mimic acts as a soluble chemokine receptor that blocks atherogenic inflammation by agonist-specific targeting
2020-11-25
0.07
Genetic predisposition to hypertension is associated with preeclampsia in European and Central Asian women
2020-11-25
0.03
Intelligent non-colorimetric indicators for the perishable supply chain by non-wovens with photo-programmed thermal response
2020-11-25
0.04
Stretchable, dynamic covalent polymers for soft, long-lived bioresorbable electronic stimulators designed to facilitate neuromuscular regeneration
2020-11-25
0.84
The genetic architecture of sporadic and multiple consecutive miscarriage
2020-11-25
0.12
Wisp1 is a circulating factor that stimulates proliferation of adult mouse and human beta cells
2020-11-25
0.14
Biomineral armor in leaf-cutter ants
2020-11-24
0.98
Common diseases alter the physiological age-related blood microRNA profile
2020-11-24
0.23
Epigenome-wide meta-analysis of PTSD across 10 military and civilian cohorts identifies methylation changes in AHRR
2020-11-24
0.85
Global hotspots for the occurrence of compound events
2020-11-24
0.05
Horizontally acquired papGII-containing pathogenicity islands underlie the emergence of invasive uropathogenic Escherichia coli lineages
2020-11-24
0.11
Intestinal FGF15/19 physiologically repress hepatic lipogenesis in the late fed-state by activating SHP and DNMT3A
2020-11-24
1
Population-scale study of eRNA transcription reveals bipartite functional enhancer architecture
2020-11-24
1
Shape-preserving erosion controlled by the graded microarchitecture of shark tooth enameloid
2020-11-24
0.13
Sub-wavelength lateral detection of tissue-approximating masses using an ultrasonic metamaterial lens
2020-11-24
0.75
Common and distinct neural representations of aversive somatic and visceral stimulation in healthy individuals
2020-11-23
0.17
Epidemiology and biology of a herpesvirus in rabies endemic vampire bat populations
2020-11-23
0.11
STRAP regulates alternative splicing fidelity during lineage commitment of mouse embryonic stem cells
2020-11-23
1
SUCLA2 mutations cause global protein succinylation contributing to the pathomechanism of a hereditary mitochondrial disease
2020-11-23
0.39
Structural basis for assembly of non-canonical small subunits into type I-C Cascade
2020-11-23
1
Structure of the respiratory MBS complex reveals iron-sulfur cluster catalyzed sulfane sulfur reduction in ancient life
2020-11-23
1
Surveying biomolecular frustration at atomic resolution
2020-11-23
0.86
TDP-43 interacts with amyloid-β, inhibits fibrillization, and worsens pathology in a model of Alzheimer’s disease
2020-11-23
0.10
The regulatory function of the AAA4 ATPase domain of cytoplasmic dynein
2020-11-23
1
An enhanced isothermal amplification assay for viral detection
2020-11-20
1
Astrocytic pyruvate dehydrogenase kinase-2 is involved in hypothalamic inflammation in mouse models of diabetes
2020-11-20
0.11
Decoding individual identity from brain activity elicited in imagining common experiences
2020-11-20
1
Dinucleosome specificity and allosteric switch of the ISW1a ATP-dependent chromatin remodeler in transcription regulation
2020-11-20
1
FAM3D is essential for colon homeostasis and host defense against inflammation associated carcinogenesis
2020-11-20
0.35
Inferring the molecular and phenotypic impact of amino acid variants with MutPred2
2020-11-20
0.83
Streamlined inactivation, amplification, and Cas13-based detection of SARS-CoV-2
2020-11-20
0.84
Structural asymmetry governs the assembly and GTPase activity of McrBC restriction complexes
2020-11-20
1
Enhanced CAR-T activity against established tumors by polarizing human T cells to secrete interleukin-9
2020-11-19
1
Functional compensation precedes recovery of tissue mass following acute liver injury
2020-11-19
0.92
PCM1 is necessary for focal ciliary integrity and is a candidate for severe schizophrenia
2020-11-19
0.82
A cross-sectional study of cardiovascular disease risk clustering at different socio-geographic levels in India
2020-11-18
0.14
Endogenous antisense RNA curbs CD39 expression in Crohn’s disease
2020-11-18
0.97
Evidences for a role of two Y-specific genes in sex determination in Populus deltoides
2020-11-18
0.08
Fibronectin-based nanomechanical biosensors to map 3D surface strains in live cells and tissue
2020-11-18
1
Genome-enabled discovery of anthraquinone biosynthesis in Senna tora
2020-11-18
0.17
Myeloid Krüppel-like factor 2 is a critical regulator of metabolic inflammation
2020-11-18
0.91
A ribosome-associated chaperone enables substrate triage in a cotranslational protein targeting complex
2020-11-17
1
Automatic classification and segmentation of single-molecule fluorescence time traces with deep learning
2020-11-17
1
Chromatin accessibility landscapes of skin cells in systemic sclerosis nominate dendritic cells in disease pathogenesis
2020-11-17
0.53
Computationally predicting clinical drug combination efficacy with cancer cell line screens and independent drug action
2020-11-17
1
Distinct oligodendrocyte populations have spatial preference and different responses to spinal cord injury
2020-11-17
0.13
Ensemble dimensionality reduction and feature gene extraction for single-cell RNA-seq data
2020-11-17
1
FIS1 encodes a GA2-oxidase that regulates fruit firmness in tomato
2020-11-17
0.08
Long non-coding RNA Gm15441 attenuates hepatic inflammasome activation in response to PPARA agonism and fasting
2020-11-17
1
Microcephalin 1/BRIT1-TRF2 interaction promotes telomere replication and repair, linking telomere dysfunction to primary microcephaly
2020-11-17
0.62
Multi-year incubation experiments boost confidence in model projections of long-term soil carbon dynamics
2020-11-17
0.79
Neuronal processes and glial precursors form a scaffold for wiring the developing mouse cochlea
2020-11-17
1
Pathologic and molecular responses to neoadjuvant trastuzumab and/or lapatinib from a phase II randomized trial in HER2-positive breast cancer (TRIO-US B07)
2020-11-17
1
Perfect absorption in complex scattering systems with or without hidden symmetries
2020-11-17
1
Pogz deficiency leads to transcription dysregulation and impaired cerebellar activity underlying autism-like behavior in mice
2020-11-17
0.21
Polycarbonate-based ultra-pH sensitive nanoparticles improve therapeutic window
2020-11-17
1
ST3GAL1 is a target of the SOX2-GLI1 transcriptional complex and promotes melanoma metastasis through AXL
2020-11-17
0.53
STAT2 signaling restricts viral dissemination but drives severe pneumonia in SARS-CoV-2 infected hamsters
2020-11-17
0.25
Two nuclear effectors of the rice blast fungus modulate host immunity via transcriptional reprogramming
2020-11-17
0.14
Upper airway gene expression reveals suppressed immune responses to SARS-CoV-2 compared with other respiratory viruses
2020-11-17
1
Vaccine elicitation of HIV broadly neutralizing antibodies from engineered B cells
2020-11-17
0.83
Alaskan carbon-climate feedbacks will be weaker than inferred from short-term experiments
2020-11-16
0.80
Deep learning-enabled breast cancer hormonal receptor status determination from base-level HE stains
2020-11-16
1
Discontinuous transition to loop formation in optimal supply networks
2020-11-16
0.33
Enhancer hijacking determines extrachromosomal circular MYCN amplicon architecture in neuroblastoma
2020-11-16
0.02
Genome of Solanum pimpinellifolium provides insights into structural variants during tomato breeding
2020-11-16
0.96
Germline AGO2 mutations impair RNA interference and human neurological development
2020-11-16
0.15
Plant hairy roots enable high throughput identification of antimicrobials against Candidatus Liberibacter spp.
2020-11-16
1
Transient commensal clonal interactions can drive tumor metastasis
2020-11-16
1
A translational program that suppresses metabolism to shield the genome
2020-11-13
0.89
Associations between blood type and COVID-19 infection, intubation, and death
2020-11-13
1
Atypical chemoreceptor arrays accommodate high membrane curvature
2020-11-13
0.56
Co-regulation of the transcription controlling ATF2 phosphoswitch by JNK and p38
2020-11-13
0.14
Complex multicomponent patterns rendered on a 3D DNA-barrel pegboard
2020-11-13
0.55
Few keystone plant genera support the majority of Lepidoptera species
2020-11-13
1
Inverse ZrO/Cu as a highly efficient methanol synthesis catalyst from CO hydrogenation
2020-11-13
0.31
Molecular estimation of neurodegeneration pseudotime in older brains
2020-11-13
1
Primary cilia mediate early life programming of adiposity through lysosomal regulation in the developing mouse hypothalamus
2020-11-13
0.06
S-nitrosylation-mediated activation of a histidine kinase represses the type 3 secretion system and promotes virulence of an enteric pathogen
2020-11-13
0.50
Vascular surveillance by haptotactic blood platelets in inflammation and infection
2020-11-13
0.07
Akt1 and dCIZ1 promote cell survival from apoptotic caspase activation during regeneration and oncogenic overgrowth
2020-11-12
0.90
Individual differences among deep neural network models
2020-11-12
0.25
Molecular structure and interactions within amyloid-like fibrils formed by a low-complexity protein sequence from FUS
2020-11-12
0.90
Pharmacological targeting of MCL-1 promotes mitophagy and improves disease pathologies in an Alzheimer’s disease mouse model
2020-11-12
0.09
Polyelectrolyte interactions enable rapid association and dissociation in high-affinity disordered protein complexes
2020-11-12
0.09
Quantitative and multiplexed chemical-genetic phenotyping in mammalian cells with QMAP-Seq
2020-11-12
1
A steric gate controls P/E hybrid-state formation of tRNA on the ribosome
2020-11-11
1
Immune responses to SARS-CoV-2 in three children of parents with symptomatic COVID-19
2020-11-11
0.13
MEKK2 mediates aberrant ERK activation in neurofibromatosis type I
2020-11-11
0.73
Viral rhodopsins 1 are an unique family of light-gated cation channels
2020-11-11
0.06
A tunable LIC1-adaptor interaction modulates dynein activity in a cargo-specific manner
2020-11-10
1
An endoribonuclease-based feedforward controller for decoupling resource-limited genetic modules in mammalian cells
2020-11-10
1
Biomaterial-based scaffold for in situ chemo-immunotherapy to treat poorly immunogenic tumors
2020-11-10
0.96
Concordant peripheral lipidome signatures in two large clinical studies of Alzheimer’s disease
2020-11-10
0.22
DNA-assembled superconducting 3D nanoscale architectures
2020-11-10
0.38
Space station biomining experiment demonstrates rare earth element extraction in microgravity and Mars gravity
2020-11-10
0.06
Strategies for simultaneous strengthening and toughening via nanoscopic intracrystalline defects in a biogenic ceramic
2020-11-10
1
Structural basis of ion transport and inhibition in ferroportin
2020-11-10
1
Systemic brain tumor delivery of synthetic protein nanoparticles for glioblastoma therapy
2020-11-10
1
Co-administered antibody improves penetration of antibody–dye conjugate into human cancers with implications for antibody–drug conjugates
2020-11-09
0.94
Cross-site transportability of an explainable artificial intelligence model for acute kidney injury prediction
2020-11-09
0.88
Human endogenous retroviruses form a reservoir of T cell targets in hematological cancers
2020-11-09
0.02
Inhibition of aquaporin-3 in macrophages by a monoclonal antibody as potential therapy for liver injury
2020-11-09
0.25
Reconstitution of prospermatogonial specification in vitro from human induced pluripotent stem cells
2020-11-09
0.61
Tree mode of death and mortality risk factors across Amazon forests
2020-11-09
0.10
A single-cell atlas and lineage analysis of the adult Drosophila ovary
2020-11-06
1
Application of an analytical framework for multivariate mediation analysis of environmental data
2020-11-06
1
Dermal IRF4+ dendritic cells and monocytes license CD4+ T helper cells to distinct cytokine profiles
2020-11-06
0.11
Designing accurate emulators for scientific processes using calibration-driven deep models
2020-11-06
1
Discovery of multiple anti-CRISPRs highlights anti-defense gene clustering in mobile genetic elements
2020-11-06
0.29
Enhanced fish production during a period of extreme global warmth
2020-11-06
1
Epidemiological hypothesis testing using a phylogeographic and phylodynamic framework
2020-11-06
0.47
From deterministic to fuzzy decision-making in artificial cells
2020-11-06
0.25
High precision epidermal radio frequency antenna via nanofiber network for wireless stretchable multifunction electronics
2020-11-06
0.02
LSH mediates gene repression through macroH2A deposition
2020-11-06
1
Scalable continuous evolution for the generation of diverse enzyme variants encompassing promiscuous activities
2020-11-06
1
Sub-nanoliter metabolomics via mass spectrometry to characterize volume-limited samples
2020-11-06
0.95
The nuclear pore primes recombination-dependent DNA synthesis at arrested forks by promoting SUMO removal
2020-11-06
0.13
mTORC1 activation in lung mesenchyme drives sex- and age-dependent pulmonary structure and function decline
2020-11-06
0.95
A circular RNA generated from an intron of the insulin gene controls insulin secretion
2020-11-05
0.02
A universal dual mechanism immunotherapy for the treatment of influenza virus infections
2020-11-05
1
ATF4 leads to glaucoma by promoting protein synthesis and ER client protein load
2020-11-05
1
Alpha-ketoglutarate ameliorates age-related osteoporosis via regulating histone methylations
2020-11-05
0.13
Molecular basis of CTCF binding polarity in genome folding
2020-11-05
0.64
Phase separation by the polyhomeotic sterile alpha motif compartmentalizes Polycomb Group proteins and enhances their activity
2020-11-05
0.22
Protrudin functions from the endoplasmic reticulum to support axon regeneration in the adult CNS
2020-11-05
0.20
Regionalized tissue fluidization is required for epithelial gap closure during insect gastrulation
2020-11-05
0.04
Spatially and cell-type resolved quantitative proteomic atlas of healthy human skin
2020-11-05
0.08
α-proteobacteria synthesize biotin precursor pimeloyl-ACP using BioZ 3-ketoacyl-ACP synthase and lysine catabolism
2020-11-05
1
Common schizophrenia risk variants are enriched in open chromatin regions of human glutamatergic neurons
2020-11-04
0.76
Discovery of driver non-coding splice-site-creating mutations in cancer
2020-11-04
1
Hormonal contraception alters vaginal microbiota and cytokines in South African adolescents in a randomized trial
2020-11-04
0.23
Integrated digital pathology and transcriptome analysis identifies molecular mediators of T-cell exclusion in ovarian cancer
2020-11-04
0.95
Metabolite signatures of diverse Camellia sinensis tea populations
2020-11-04
0.07
Sigma-1 receptor chaperones rescue nucleocytoplasmic transport deficit seen in cellular and ALS/FTD models
2020-11-04
0.50
Small molecules as potent biphasic modulators of protein liquid-liquid phase separation
2020-11-04
1
Systematic elucidation of neuron-astrocyte interaction in models of amyotrophic lateral sclerosis using multi-modal integrated bioinformatics workflow
2020-11-04
0.86
The persistence potential of transferable plasmids
2020-11-04
1
ArfB can displace mRNA to rescue stalled ribosomes
2020-11-03
1
BrainPhys neuronal medium optimized for imaging and optogenetics in vitro
2020-11-03
0.07
Broad genic repression domains signify enhanced silencing of oncogenes
2020-11-03
1
Efficient population modification gene-drive rescue system in the malaria mosquito
2020-11-03
0.96
Expanding the genetic architecture of nicotine dependence and its shared genetics with multiple traits
2020-11-03
0.77
Functional characterization of variants identified by targeted exome-sequencing of 131,668 cancer patients
2020-11-03
1
Nearest-neighbor NMR spectroscopy: categorizing spectral peaks by their adjacent nuclei
2020-11-03
0.90
Rapid and robust assembly and decoding of molecular tags with DNA-based nanopore signatures
2020-11-03
1
Revealing fine-scale spatiotemporal differences in SARS-CoV-2 introduction and spread
2020-11-03
1
Role of specialized composition of SWI/SNF complexes in prostate cancer lineage plasticity
2020-11-03
0.50
The HUSH complex is a gatekeeper of type I interferon through epigenetic regulation of LINE-1s
2020-11-03
0.08
cAMP-dependent regulation of HCN4 controls the tonic entrainment process in sinoatrial node pacemaker cells
2020-11-03
0.10
A catalogue of biochemically diverse CRISPR-Cas9 orthologs
2020-11-02
0.64
APOE4 exacerbates synapse loss and neurodegeneration in Alzheimer’s disease patient iPSC-derived cerebral organoids
2020-11-02
1
An HDAC6-dependent surveillance mechanism suppresses tau-mediated neurodegeneration and cognitive decline
2020-11-02
1
Armadillo-repeat kinesin1 interacts with Arabidopsis atlastin RHD3 to move ER with plus-end of microtubules
2020-11-02
0.10
CFAP45 deficiency causes situs abnormalities and asthenospermia by disrupting an axonemal adenine nucleotide homeostasis module
2020-11-02
0.10
Epigenetic conflict on a degenerating Y chromosome increases mutational burden in Drosophila males
2020-11-02
1
Evolutionary and functional genomics of DNA methylation in maize domestication and improvement
2020-11-02
0.72
Full genome viral sequences inform patterns of SARS-CoV-2 spread into and within Israel
2020-11-02
0.11
Gamma estimator of Jarzynski equality for recovering binding energies from noisy dynamic data sets
2020-11-02
0.67
Open syntaxin overcomes exocytosis defects of diverse mutants in
2020-11-02
0.17
Rapid and accurate determination of atomistic RNA dynamic ensemble models using NMR and structure prediction
2020-11-02
1
Optimized design of single-cell RNA sequencing experiments for cell-type-specific eQTL analysis
2020-10-30
1
Proline rich 11 (PRR11) overexpression amplifies PI3K signaling and promotes antiestrogen resistance in breast cancer
2020-10-30
1
SARS-CoV-2 viral load is associated with increased disease severity and mortality
2020-10-30
1
SDE2 integrates into the TIMELESS-TIPIN complex to protect stalled replication forks
2020-10-30
0.55
Towards a reference genome that captures global genetic diversity
2020-10-30
0.41
Combating acquired resistance to MAPK inhibitors in melanoma by targeting Abl1/2-mediated reactivation of MEK/ERK/MYC signaling
2020-10-29
1
Intellectual disability-associated factor Zbtb11 cooperates with NRF-2/GABP to control mitochondrial function
2020-10-29
0.14
Molecular mechanism of the MORC4 ATPase activation
2020-10-29
1
Multiple imputation for analysis of incomplete data in distributed health data networks
2020-10-29
1
Mutualistic networks emerging from adaptive niche-based interactions
2020-10-29
1
A self-powered analog sensor-data-logging device based on Fowler-Nordheim dynamical systems
2020-10-28
1
ACE2 localizes to the respiratory cilia and is not increased by ACE inhibitors or ARBs
2020-10-28
0.65
Genome biology of the paleotetraploid perennial biomass crop
2020-10-28
0.61
Genotype by environment interaction for gene expression in Drosophila melanogaster
2020-10-28
1
Integrative transcriptome and chromatin landscape analysis reveals distinct epigenetic regulations in human memory B cells
2020-10-28
1
Murine interfollicular epidermal differentiation is gradualistic with GRHL3 controlling progression from stem to transition cell states
2020-10-28
1
Natural variations of SLG1 confer high-temperature tolerance in indica rice
2020-10-28
0.14
Capturing human categorization of natural images by combining deep networks and cognitive models
2020-10-27
1
Disease burden and clinical severity of the first pandemic wave of COVID-19 in Wuhan, China
2020-10-27
0.17
Local community assembly mechanisms shape soil bacterial β diversity patterns along a latitudinal gradient
2020-10-27
0.25
Modeling early stage atherosclerosis in a primary human vascular microphysiological system
2020-10-27
0.94
Neutrophil-induced ferroptosis promotes tumor necrosis in glioblastoma progression
2020-10-27
1
Origin of rebound virus in chronically SIV-infected Rhesus monkeys following treatment discontinuation
2020-10-27
1
Overcoming primary and acquired resistance to anti-PD-L1 therapy by induction and activation of tumor-residing cDC1s
2020-10-27
1
Structural basis for potent neutralization of SARS-CoV-2 and role of antibody affinity maturation
2020-10-27
1
Structure of human steroid 5α-reductase 2 with the anti-androgen drug finasteride
2020-10-27
0.30
A multiresolution framework to characterize single-cell state landscapes
2020-10-26
1
Automated and optimally FRET-assisted structural modeling
2020-10-26
0.06
Differential reinforcement encoding along the hippocampal long axis helps resolve the explore–exploit dilemma
2020-10-26
1
Mendelian randomization study of maternal influences on birthweight and future cardiometabolic risk in the HUNT cohort
2020-10-26
0.23
Slug regulates the Dll4-Notch-VEGFR2 axis to control endothelial cell activation and angiogenesis
2020-10-26
1
T cell-intrinsic role for Nod2 in protection against Th17-mediated uveitis
2020-10-26
0.90
The evolution of tit-for-tat in bacteria via the type VI secretion system
2020-10-26
0.14
Vortex phase matching as a strategy for schooling in robots and in fish
2020-10-26
0.17
A particle-field approach bridges phase separation and collective motion in active matter
2020-10-23
0.33
Brainstem development requires galactosylceramidase and is critical for pathogenesis in a model of Krabbe disease
2020-10-23
1
Exponentially-enhanced quantum sensing with non-Hermitian lattice dynamics
2020-10-23
1
Gene expression and functional deficits underlie TREM2-knockout microglia responses in human models of Alzheimer’s disease
2020-10-23
0.97
General destabilizing effects of eutrophication on grassland productivity at multiple spatial scales
2020-10-23
0.36
Genome-scale metabolic rewiring improves titers rates and yields of the non-native product indigoidine at scale
2020-10-23
0.98
Increased power from conditional bacterial genome-wide association identifies macrolide resistance mutations in Neisseria gonorrhoeae
2020-10-23
0.71
Learning the non-equilibrium dynamics of Brownian movies
2020-10-23
0.25
MEPE loss-of-function variant associates with decreased bone mineral density and increased fracture risk
2020-10-23
0.78
Polymerization and editing modes of a high-fidelity DNA polymerase are linked by a well-defined path
2020-10-23
0.50
Seasonal modulation of phytoplankton biomass in the Southern Ocean
2020-10-23
1
Sensing of autoinducer-2 by functionally distinct receptors in prokaryotes
2020-10-23
0.06
Shortwave-infrared meso-patterned imaging enables label-free mapping of tissue water and lipid content
2020-10-23
0.93
The nucleotide pGpp acts as a third alarmone in Bacillus, with functions distinct from those of (p) ppGpp
2020-10-23
1
USP52 regulates DNA end resection and chemosensitivity through removing inhibitory ubiquitination from CtIP
2020-10-23
0.96
Carotenoids modulate kernel texture in maize by influencing amyloplast envelope integrity
2020-10-22
0.08
Low cost DNA data storage using photolithographic synthesis and advanced information reconstruction and error correction
2020-10-22
0.21
MSH1-induced heritable enhanced growth vigor through grafting is associated with the RdDM pathway in plants
2020-10-22
1
Marine plankton show threshold extinction response to Neogene climate change
2020-10-22
0.50
Clonal evolution of acute myeloid leukemia revealed by high-throughput single-cell genomics
2020-10-21
0.88
Dual mRNA therapy restores metabolic function in long-term studies in mice with propionic acidemia
2020-10-21
1
Sensitivity enhancement of homonuclear multidimensional NMR correlations for labile sites in proteins, polysaccharides, and nucleic acids
2020-10-21
0.29
Synaptic vesicle traffic is supported by transient actin filaments and regulated by PKA and NO
2020-10-21
0.89
Vestigial-like 1 is a shared targetable cancer-placenta antigen expressed by pancreatic and basal-like breast cancers
2020-10-21
1
AKAP5 complex facilitates purinergic modulation of vascular L-type Ca2+ channel CaV1.2
2020-10-20
1
Altered G1 signaling order and commitment point in cells proliferating without CDK4/6 activity
2020-10-20
0.74
CHIP phosphorylation by protein kinase G enhances protein quality control and attenuates cardiac ischemic injury
2020-10-20
1
Contribution of GATA6 to homeostasis of the human upper pilosebaceous unit and acne pathogenesis
2020-10-20
0.03
Genome-wide association study of smoking trajectory and meta-analysis of smoking status in 842,000 individuals
2020-10-20
1
Mechanisms of telomerase inhibition by oxidized and therapeutic dNTPs
2020-10-20
1
Prevalent and sex-biased breathing patterns modify functional connectivity MRI in young adults
2020-10-20
1
Siah2 integrates mitogenic and extracellular matrix signals linking neuronal progenitor ciliogenesis with germinal zone occupancy
2020-10-20
1
The tomato receptor CuRe1 senses a cell wall protein to identify Cuscuta as a pathogen
2020-10-20
0.08
Antibodies targeting epitopes on the cell-surface form of NS1 protect against Zika virus infection during pregnancy
2020-10-19
0.79
Automated microfluidic platform for dynamic and combinatorial drug screening of tumor organoids
2020-10-19
1
Detection of early stage pancreatic cancer using 5-hydroxymethylcytosine signatures in circulating cell free DNA
2020-10-19
1
Integration of time-series meta-omics data reveals how microbial ecosystems respond to disturbance
2020-10-19
0.33
Mutations associated with neuropsychiatric conditions delineate functional brain connectivity dimensions contributing to autism and schizophrenia
2020-10-19
0.14
The structure of a red-shifted photosystem I reveals a red site in the core antenna
2020-10-19
1
Cryopreservation impairs 3-D migration and cytotoxicity of natural killer cells
2020-10-16
0.07
DIALib-QC an assessment tool for spectral libraries in data-independent acquisition proteomics
2020-10-16
1
Detection of haplotype-dependent allele-specific DNA methylation in WGBS data
2020-10-16
1
Genome-wide screens identify Toxoplasma gondii determinants of parasite fitness in IFNγ-activated murine macrophages
2020-10-16
0.83
Increased RNA editing in maternal immune activation model of neurodevelopmental disease
2020-10-16
0.33
Language prediction mechanisms in human auditory cortex
2020-10-16
1
Metformin enhances anti-mycobacterial responses by educating CD8+ T-cell immunometabolic circuits
2020-10-16
0.33
Multivalent interactions drive nucleosome binding and efficient chromatin deacetylation by SIRT6
2020-10-16
1
Non-invasive decision support for NSCLC treatment using PET/CT radiomics
2020-10-16
0.46
Photon-directed multiplexed enzymatic DNA synthesis for molecular digital data storage
2020-10-16
0.86
Standardization and harmonization of distributed multi-center proteotype analysis supporting precision medicine studies
2020-10-16
0.17
Understanding and managing new risks on the Nile with the Grand Ethiopian Renaissance Dam
2020-10-16
0.50
Whole-genome sequencing of acral melanoma reveals genomic complexity and diversity
2020-10-16
0.17
A nanoluciferase SARS-CoV-2 for rapid neutralization testing and screening of anti-infective drugs for COVID-19
2020-10-15
1
Aberrant methylation underlies insulin gene expression in human insulinoma
2020-10-15
0.90
Health and disease markers correlate with gut microbiome composition across thousands of people
2020-10-15
1
Lyn kinase regulates egress of flaviviruses in autophagosome-derived organelles
2020-10-15
0.25
Stress-induced RNA–chromatin interactions promote endothelial dysfunction
2020-10-15
0.96
Topaz-Denoise: general deep denoising models for cryoEM and cryoET
2020-10-15
1
A strategy to incorporate prior knowledge into correlation network cutoff selection
2020-10-14
0.10
CRISPR screening of porcine sgRNA library identifies host factors associated with Japanese encephalitis virus replication
2020-10-14
0.06
Evolution of DNA replication origin specification and gene silencing mechanisms
2020-10-14
0.89
Fungal oxylipins direct programmed developmental switches in filamentous fungi
2020-10-14
0.79
Genome-wide translational profiling of amygdala Crh-expressing neurons reveals role for CREB in fear extinction learning
2020-10-14
1
Pan-cancer analysis reveals TAp63-regulated oncogenic lncRNAs that promote cancer progression through AKT activation
2020-10-14
0.88
Pan-neuroblastoma analysis reveals age- and signature-associated driver alterations
2020-10-14
1
Plant species determine tidal wetland methane response to sea level rise
2020-10-14
0.92
Smell and taste changes are early indicators of the COVID-19 pandemic and political decision effectiveness
2020-10-14
0.25
Synapse type-specific proteomic dissection identifies IgSF8 as a hippocampal CA3 microcircuit organizer
2020-10-14
0.19
Th17-inducing autologous dendritic cell vaccination promotes antigen-specific cellular and humoral immunity in ovarian cancer patients
2020-10-14
1
The structural variation landscape in 492 Atlantic salmon genomes
2020-10-14
0.04
Whole genome sequence analysis of pulmonary function and COPD in 19,996 multi-ethnic participants
2020-10-14
0.94
Leptin alters energy intake and fat mass but not energy expenditure in lean subjects
2020-10-13
0.86
Single-cell RNA cap and tail sequencing (scRCAT-seq) reveals subtype-specific isoforms differing in transcript demarcation
2020-10-13
0.33
AKT-induced lncRNA VAL promotes EMT-independent metastasis through diminishing Trim16-dependent Vimentin degradation
2020-10-12
0.06
Andean drought and glacial retreat tied to Greenland warming during the last glacial period
2020-10-12
0.83
COMPOSITUM 1 contributes to the architectural simplification of barley inflorescence via meristem identity signals
2020-10-12
0.06
Deep transfer learning for reducing health care disparities arising from biomedical data inequality
2020-10-12
1
High-throughput mutagenesis reveals unique structural features of human ADAR1
2020-10-12
0.90
Jagged1-Notch1-deployed tumor perivascular niche promotes breast cancer stem cell phenotype through Zeb1
2020-10-12
0.07
Large-scale genome sequencing of mycorrhizal fungi provides insights into the early evolution of symbiotic traits
2020-10-12
0.41
Multi-functional flexible 2D carbon nanostructured networks
2020-10-12
0.25
NOTCH1 gene amplification promotes expansion of Cancer Associated Fibroblast populations in human skin
2020-10-12
0.45
TERMINAL FLOWER 1-FD complex target genes and competition with FLOWERING LOCUS T
2020-10-12
0.86
Type 2 and interferon inflammation regulate SARS-CoV-2 entry factor expression in the airway epithelium
2020-10-12
1
Accommodating individual travel history and unsampled diversity in Bayesian phylogeographic inference of SARS-CoV-2
2020-10-09
0.31
Adaptive thermogenesis enhances the life-threatening response to heat in mice with an Ryr1 mutation
2020-10-09
0.87
Identification of 31 loci for mammographic density phenotypes and their associations with breast cancer risk
2020-10-09
0.90
Polysynaptic inhibition between striatal cholinergic interneurons shapes their network activity patterns in a dopamine-dependent manner
2020-10-09
0.31
Rational design of a microbial consortium of mucosal sugar utilizers reduces Clostridiodes difficile colonization
2020-10-09
0.07
Reconstructing the maize leaf regulatory network using ChIP-seq data of 104 transcription factors
2020-10-09
0.27
Structural insights into assembly of the ribosomal nascent polypeptide exit tunnel
2020-10-09
0.67
Synthesis runs counter to directional folding of a nascent protein domain
2020-10-09
1
The ALPK1/TIFA/NF-κB axis links a bacterial carcinogen to R-loop-induced replication stress
2020-10-09
0.20
The reductive glycine pathway allows autotrophic growth of Desulfovibrio desulfuricans
2020-10-09
0.11
A gene expression signature of TREM2hi macrophages and γδ T cells predicts immunotherapy response
2020-10-08
1
A spinal neural circuitry for converting touch to itch sensation
2020-10-08
0.63
AP-1 and TGFß cooperativity drives non-canonical Hedgehog signaling in resistant basal cell carcinoma
2020-10-08
1
CryoEM structure of the type IVa pilus secretin required for natural competence in Vibrio cholerae
2020-10-08
1
Endoplasmic reticulum visits highly active spines and prevents runaway potentiation of synapses
2020-10-08
0.17
GABAergic motor neurons bias locomotor decision-making in C. elegans
2020-10-08
0.83
Genome-wide chromatin accessibility is restricted by ANP32E
2020-10-08
1
Global distribution and conservation status of ecologically rare mammal and bird species
2020-10-08
0.23
Intermolecular channels direct crystal orientation in mineralized collagen
2020-10-08
0.08
Prostate cancer evolution from multilineage primary to single lineage metastases with implications for liquid biopsy
2020-10-08
0.28
Single-cell RNA sequencing highlights the role of inflammatory cancer-associated fibroblasts in bladder urothelial carcinoma
2020-10-08
0.13
The hierarchical assembly of septins revealed by high-speed AFM
2020-10-08
1
Two distinct immunopathological profiles in autopsy lungs of COVID-19
2020-10-08
0.03
A deep learning approach to programmable RNA switches
2020-10-07
1
CRISPRoff enables spatio-temporal control of CRISPR editing
2020-10-07
1
Framework for quality assessment of whole genome cancer sequences
2020-10-07
0.29
Identification of epilepsy-associated neuronal subtypes and gene expression underlying epileptogenesis
2020-10-07
0.09
In primary airway epithelial cells, the unjamming transition is distinct from the epithelial-to-mesenchymal transition
2020-10-07
0.83
PilY1 and minor pilins form a complex priming the type IVa pilus in Myxococcus xanthus
2020-10-07
0.38
Reconstructing lost BOLD signal in individual participants using deep machine learning
2020-10-07
0.34
Sequence-to-function deep learning frameworks for engineered riboregulators
2020-10-07
1
Suppressing material loss in the visible and near-infrared range for functional nanophotonics using bandgap engineering
2020-10-07
0.83
Accelerated knowledge discovery from omics data by optimal experimental design
2020-10-06
1
Adaptation and selection shape clonal evolution of tumors during residual disease and recurrence
2020-10-06
1
An avian cortical circuit for chunking tutor song syllables into simple vocal-motor units
2020-10-06
1
Authentic self-expression on social media is associated with greater subjective well-being
2020-10-06
1
Deep phenotyping of 34,128 adult patients hospitalised with COVID-19 in an international network study
2020-10-06
0.53
Gut microbiome-related effects of berberine and probiotics on type 2 diabetes (the PREMOTE study)
2020-10-06
0.03
In situ reprogramming of gut bacteria by oral delivery
2020-10-06
1
Mechanism and evolution of the Zn-fingernail required for interaction of VARP with VPS29
2020-10-06
0.03
Metastable hybridization-based DNA information storage to allow rapid and permanent erasure
2020-10-06
1
Millisecond dynamics of an unlabeled amino acid transporter
2020-10-06
1
Prophage exotoxins enhance colonization fitness in epidemic scarlet fever-causing Streptococcus pyogenes
2020-10-06
0.05
Protease circuits for processing biological information
2020-10-06
1
Structural basis for the transition from translation initiation to elongation by an 80S-eIF5B complex
2020-10-06
1
Tailoring poplar lignin without yield penalty by combining a null and haploinsufficient CINNAMOYL-CoA REDUCTASE2 allele
2020-10-06
0.20
The Rho-GEF PIX-1 directs assembly or stability of lateral attachment structures between muscle cells
2020-10-06
1
p50 mono-ubiquitination and interaction with BARD1 regulates cell cycle progression and maintains genome stability
2020-10-06
1
Chronic glucose-dependent insulinotropic polypeptide receptor (GIPR) agonism desensitizes adipocyte GIPR activity mimicking functional GIPR antagonism
2020-10-05
1
Crop switching reduces agricultural losses from climate change in the United States by half under RCP 8.5
2020-10-05
0.50
Distinct signatures of gut microbiome and metabolites associated with significant fibrosis in non-obese NAFLD
2020-10-05
0.08
Genetic circuit characterization by inferring RNA polymerase movement and ribosome usage
2020-10-05
1
Glioma-derived IL-33 orchestrates an inflammatory brain tumor microenvironment that accelerates glioma progression
2020-10-05
0.14
Monitoring and modeling of lymphocytic leukemia cell bioenergetics reveals decreased ATP synthesis during cell division
2020-10-05
0.97
Movie viewing elicits rich and reliable brain state dynamics
2020-10-05
0.20
Cryo-EM structure of a Ca2+-bound photosynthetic LH1-RC complex containing multiple αβ-polypeptides
2020-10-02
0.08
D-serine mitigates cell loss associated with temporal lobe epilepsy
2020-10-02
1
Disease trajectory browser for exploring temporal, population-wide disease progression patterns in 7.2 million Danish patients
2020-10-02
0.05
Evolution of communication signals and information during species radiation
2020-10-02
0.13
Functional role of Tet-mediated RNA hydroxymethylcytosine in mouse ES cells and during differentiation
2020-10-02
0.13
Identification of a pocket factor that is critical to Zika virus assembly
2020-10-02
1
Multi-omics prediction of immune-related adverse events during checkpoint immunotherapy
2020-10-02
0.62
PQM-1 controls hypoxic survival via regulation of lipid metabolism
2020-10-02
0.42
Phylogenomic analysis sheds light on the evolutionary pathways towards acoustic communication in Orthoptera
2020-10-02
0.19
Real-world data from a molecular tumor board demonstrates improved outcomes with a precision N-of-One strategy
2020-10-02
0.95
SARS-CoV2-mediated suppression of NRF2-signaling reveals potent antiviral and anti-inflammatory activity of 4-octyl-itaconate and dimethyl fumarate
2020-10-02
0.05
Selective inhibition of human translation termination by a drug-like compound
2020-10-02
1
Targeted scavenging of extracellular ROS relieves suppressive immunogenic cell death
2020-10-02
0.69
Chromatin accessibility landscape and regulatory network of high-altitude hypoxia adaptation
2020-10-01
0.17
Deep longitudinal multiomics profiling reveals two biological seasonal patterns in California
2020-10-01
1
Genomics of the Argentinian cholera epidemic elucidate the contrasting dynamics of epidemic and endemic Vibrio cholerae
2020-10-01
0.03
Large-scale targeted sequencing identifies risk genes for neurodevelopmental disorders
2020-10-01
0.78
Local-scale Arctic tundra heterogeneity affects regional-scale carbon dynamics
2020-10-01
0.78
Non-invasive molecularly-specific millimeter-resolution manipulation of brain circuits by ultrasound-mediated aggregation and uncaging of drug carriers
2020-10-01
0.05
PINCH-1 regulates mitochondrial dynamics to promote proline synthesis and tumor growth
2020-10-01
0.10
Structural basis for substrate recognition and chemical inhibition of oncogenic MAGE ubiquitin ligases
2020-10-01
1
Enhancement of trans-cleavage activity of Cas12a with engineered crRNA enables amplified nucleic acid detection
2020-09-30
1
Genetic variant effects on gene expression in human pancreatic islets and their implications for T2D
2020-09-30
0.37
Hybrid cellular membrane nanovesicles amplify macrophage immune responses against cancer recurrence and metastasis
2020-09-30
0.52
Gene-informed decomposition model predicts lower soil carbon loss due to persistent microbial adaptation to warming
2020-09-29
0.79
Homopolymer self-assembly of poly(propylene sulfone) hydrogels via dynamic noncovalent sulfone–sulfone bonding
2020-09-29
1
Satellite glial cells promote regenerative growth in sensory neurons
2020-09-29
1
Stress fiber anisotropy contributes to force-mode dependent chromatin stretching and gene upregulation in living cells
2020-09-29
0.17
CLR01 protects dopaminergic neurons in vitro and in mouse models of Parkinson’s disease
2020-09-28
0.14
Mapping the bacterial metabolic niche space
2020-09-28
0.63
Modeling lung perfusion abnormalities to explain early COVID-19 hypoxemia
2020-09-28
1
STAT5 promotes accessibility and is required for BATF-mediated plasticity at the Il9 locus
2020-09-28
1
Viral gene drive in herpesviruses
2020-09-28
1
A data-driven simulation platform to predict cultivars’ performances under uncertain weather conditions
2020-09-25
0.20
A machine learning Automated Recommendation Tool for synthetic biology
2020-09-25
0.94
A trimeric CrRLK1L-LLG1 complex genetically modulates SUMM2-mediated autoimmunity
2020-09-25
0.60
Combining mechanistic and machine learning models for predictive engineering and optimization of tryptophan metabolism
2020-09-25
0.39
DeSiphering receptor core-induced and ligand-dependent conformational changes in arrestin via genetic encoded trimethylsilyl H-NMR probe
2020-09-25
0.06
Engineering and application of a biosensor with focused ligand specificity
2020-09-25
0.10
Face selective patches in marmoset frontal cortex
2020-09-25
0.17
Integrative genomics identifies a convergent molecular subtype that links epigenomic with transcriptomic differences in autism
2020-09-25
0.60
Mycobacterium tuberculosis progresses through two phases of latent infection in humans
2020-09-25
0.71
Poly(ADP-ribose) glycohydrolase coordinates meiotic DNA double-strand break induction and repair independent of its catalytic activity
2020-09-25
0.33
Polyunsaturated fatty acids and p38-MAPK link metabolic reprogramming to cytoprotective gene expression during dietary restriction
2020-09-25
0.28
Radiogenomic signatures reveal multiscale intratumour heterogeneity associated with biological functions and survival in breast cancer
2020-09-25
0.40
Yeast homologs of human MCUR1 regulate mitochondrial proline metabolism
2020-09-25
0.86
Bone morphogenetic protein 7 promotes resistance to immunotherapy
2020-09-24
1
Functional genetic encoding of sulfotyrosine in mammalian cells
2020-09-24
0.91
Laser-induced graphitization of polydopamine leads to enhanced mechanical performance while preserving multifunctionality
2020-09-24
0.89
MFSD7C switches mitochondrial ATP synthesis to thermogenesis in response to heme
2020-09-24
1
PD-L1 on dendritic cells attenuates T cell activation and regulates response to immune checkpoint blockade
2020-09-24
0.36
Phase I clinical trial repurposing all-trans retinoic acid as a stromal targeting agent for pancreatic cancer
2020-09-24
0.02
Raman-guided subcellular pharmaco-metabolomics for metastatic melanoma cells
2020-09-24
1
Very-Low-Frequency transmitters bifurcate energetic electron belt in near-earth space
2020-09-24
0.63
Dental cell type atlas reveals stem and differentiated cell types in mouse and human teeth
2020-09-23
0.27
Efficacy of anti-CD147 chimeric antigen receptors targeting hepatocellular carcinoma
2020-09-23
1
Ensemble-based enzyme design can recapitulate the effects of laboratory directed evolution in silico
2020-09-23
0.33
Genetic screens reveal a central role for heme metabolism in artemisinin susceptibility
2020-09-23
0.85
Macrophage secretion of miR-106b-5p causes renin-dependent hypertension
2020-09-23
0.95
Multiplatform genomic profiling and magnetic resonance imaging identify mechanisms underlying intratumor heterogeneity in meningioma
2020-09-23
1
REM sleep promotes experience-dependent dendritic spine elimination in the mouse cortex
2020-09-23
0.48
Repurposing anti-inflammasome NRTIs for improving insulin sensitivity and reducing type 2 diabetes development
2020-09-23
0.95
Risk prediction of late-onset Alzheimer’s disease implies an oligogenic architecture
2020-09-23
0.04
T-Plastin reinforces membrane protrusions to bridge matrix gaps during cell migration
2020-09-23
1
Transcriptomic profiling of human cardiac cells predicts protein kinase inhibitor-associated cardiotoxicity
2020-09-23
0.97
A cell-type deconvolution meta-analysis of whole blood EWAS reveals lineage-specific smoking-associated DNA methylation changes
2020-09-22
0.03
A diploid assembly-based benchmark for variants in the major histocompatibility complex
2020-09-22
0.88
Chiral gold nanoparticles enantioselectively rescue memory deficits in a mouse model of Alzheimer’s disease
2020-09-22
0.07
Enteroendocrine cells couple nutrient sensing to nutrient absorption by regulating ion transport
2020-09-22
1
Genetic correlations and genome-wide associations of cortical structure in general population samples of 22,824 adults
2020-09-22
0.29
IL-33-ST2 axis regulates myeloid cell differentiation and activation enabling effective club cell regeneration
2020-09-22
0.58
IRES-targeting small molecule inhibits enterovirus 71 replication via allosteric stabilization of a ternary complex
2020-09-22
1
Structural snapshots of human DNA polymerase μ engaged on a DNA double-strand break
2020-09-22
1
Summer warming explains widespread but not uniform greening in the Arctic tundra biome
2020-09-22
0.57
Ultra-sensitive and rapid detection of nucleic acids and microorganisms in body fluids using single-molecule tethering
2020-09-22
1
A predictable conserved DNA base composition signature defines human core DNA replication origins
2020-09-21
0.03
Estimating retention benchmarks for salvage logging to protect biodiversity
2020-09-21
0.13
Macroecological laws describe variation and diversity in microbial communities
2020-09-21
0.50
Optical imaging of single-protein size, charge, mobility, and binding
2020-09-21
1
Regulation of cellular sterol homeostasis by the oxygen responsive noncoding RNA lincNORS
2020-09-21
0.71
Telomere dysfunction activates YAP1 to drive tissue inflammation
2020-09-21
0.96
Visual mate preference evolution during butterfly speciation is linked to neural processing genes
2020-09-21
0.15
A quantitative framework reveals ecological drivers of grassland microbial community assembly in response to warming
2020-09-18
0.73
Association of APOE e2 genotype with Alzheimer’s and non-Alzheimer’s neurodegenerative pathologies
2020-09-18
1
DR3 stimulation of adipose resident ILC2s ameliorates type 2 diabetes mellitus
2020-09-18
1
DsbA-L mediated renal tubulointerstitial fibrosis in UUO mice
2020-09-18
0.03
Preferred crystallographic orientation of cellulose in plant primary cell walls
2020-09-18
1
Rapid and direct control of target protein levels with VHL-recruiting dTAG molecules
2020-09-18
1
Retrieving functional pathways of biomolecules from single-particle snapshots
2020-09-18
1
The influence of soil age on ecosystem structure and function across biomes
2020-09-18
0.33
Ultrasensitive and visual detection of SARS-CoV-2 using all-in-one dual CRISPR-Cas12a assay
2020-09-18
1
A systematic review of antibody mediated immunity to coronaviruses: kinetics, correlates of protection, and association with severity
2020-09-17
0.94
Chromatin remodeling in bovine embryos indicates species-specific regulation of genome activation
2020-09-17
0.90
Eukaryotic cell biology is temporally coordinated to support the energetic demands of protein homeostasis
2020-09-17
0.20
Evaluating the informativeness of deep learning annotations for human complex diseases
2020-09-17
1
Multiple capsid protein binding sites mediate selective packaging of the alphavirus genomic RNA
2020-09-17
1
Pressure-stabilized divalent ozonide CaO3 and its impact on Earth’s oxygen cycles
2020-09-17
0.17
Rapid incorporation of Favipiravir by the fast and permissive viral RNA polymerase complex results in SARS-CoV-2 lethal mutagenesis
2020-09-17
0.08
SARS-CoV-2 seroprevalence and neutralizing activity in donor and patient blood
2020-09-17
1
Deregulated immune cell recruitment orchestrated by FOXM1 impairs human diabetic wound healing
2020-09-16
1
Glioma-initiating cells at tumor edge gain signals from tumor core cells to promote their malignancy
2020-09-16
0.64
Improved haplotype inference by exploiting long-range linking and allelic imbalance in RNA-seq datasets
2020-09-16
0.96
Intercalated disc protein Xinβ is required for Hippo-YAP signaling in the heart
2020-09-16
0.81
Phase of firing coding of learning variables across the fronto-striatal network during feature-based learning
2020-09-16
1
Potential impacts of mercury released from thawing permafrost
2020-09-16
1
Reductions in commuting mobility correlate with geographic differences in SARS-CoV-2 prevalence in New York City
2020-09-16
1
Time-restricted feeding alters lipid and amino acid metabolite rhythmicity without perturbing clock gene expression
2020-09-16
0.20
Translational induction of ATF4 during integrated stress response requires noncanonical initiation factors eIF2D and DENR
2020-09-16
1
A predictive index for health status using species-level gut microbiome profiling
2020-09-15
1
A shared genetic contribution to breast cancer and schizophrenia
2020-09-15
0.25
Age and life expectancy clocks based on machine learning analysis of mouse frailty
2020-09-15
0.80
Environmental variability supports chimpanzee behavioural diversity
2020-09-15
0.13
Light microscopy based approach for mapping connectivity with molecular specificity
2020-09-15
1
NEMF mutations that impair ribosome-associated quality control are associated with neuromuscular disease
2020-09-15
0.45
Pharmacophore hybridisation and nanoscale assembly to discover self-delivering lysosomotropic new-chemical entities for cancer therapy
2020-09-15
0.84
Phenotypic profiling with a living biobank of primary rhabdomyosarcoma unravels disease heterogeneity and AKT sensitivity
2020-09-15
0.11
Photoswitchable paclitaxel-based microtubule stabilisers allow optical control over the microtubule cytoskeleton
2020-09-15
0.21
TET2 directs mammary luminal cell differentiation and endocrine response
2020-09-15
0.73
Temperate infection in a virus–host system previously known for virulent dynamics
2020-09-15
0.83
An investigation of causal relationships between prediabetes and vascular complications
2020-09-14
0.02
Caspase-8 mediates inflammation and disease in rodent malaria
2020-09-14
0.42
Chromatin accessibility mapping of the striatum identifies tyrosine kinase FYN as a therapeutic target for heroin use disorder
2020-09-14
0.94
Dual blockade of CD47 and HER2 eliminates radioresistant breast cancer cells
2020-09-14
0.91
Effectiveness of protected areas in conserving tropical forest birds
2020-09-14
0.06
Ignoring correlated activity causes a failure of retinal population codes
2020-09-14
0.67
Prior knowledge promotes hippocampal separation but cortical assimilation in the left inferior frontal gyrus
2020-09-14
0.33
Senescence and entrenchment in evolution of amino acid sites
2020-09-14
0.07
A meta-analysis on decomposition quantifies afterlife effects of plant diversity as a global change driver
2020-09-11
0.20
Accelerating eye movement research via accurate and affordable smartphone eye tracking
2020-09-11
1
Allosteric coupling between α-rings of the 20S proteasome
2020-09-11
1
Automated markerless pose estimation in freely moving macaques with OpenMonkeyStudio
2020-09-11
1
Concerted localization-resets precede YAP-dependent transcription
2020-09-11
1
Demography and the emergence of universal patterns in urban systems
2020-09-11
1
Diversity analysis of 80,000 wheat accessions reveals consequences and opportunities of selection footprints
2020-09-11
0.02
Ecosystem-based fisheries management forestalls climate-driven collapse
2020-09-11
0.97
Elucidating the role of metal ions in carbonic anhydrase catalysis
2020-09-11
0.25
Hyperacetylated chromatin domains mark cell type-specific genes and suggest distinct modes of enhancer function
2020-09-11
1
Just ten percent of the global terrestrial protected area network is structurally connected via intact land
2020-09-11
0.04
Middle-aged individuals may be in a perpetual state of H3N2 influenza virus susceptibility
2020-09-11
1
Nucleoporin TPR is an integral component of the TREX-2 mRNA export pathway
2020-09-11
1
Ontogeny of arterial macrophages defines their functions in homeostasis and inflammation
2020-09-11
0.13
Predicting the frequencies of drug side effects
2020-09-11
0.50
Spatial validation reveals poor predictive performance of large-scale ecological mapping models
2020-09-11
0.08
Using insurance data to quantify the multidimensional impacts of warming temperatures on yield risk
2020-09-11
1
DNA methylation study of Huntington’s disease and motor progression in patients and in animal models
2020-09-10
0.58
Intratumoral generation of photothermal gold nanoparticles through a vectorized biomineralization of ionic gold
2020-09-10
1
Meningeal lymphatic dysfunction exacerbates traumatic brain injury pathogenesis
2020-09-10
1
Natural emotion vocabularies as windows on distress and well-being
2020-09-10
0.67
Real-time monitoring of single ZTP riboswitches reveals a complex and kinetically controlled decision landscape
2020-09-10
1
A distinct lineage of Caudovirales that encodes a deeply branching multi-subunit RNA polymerase
2020-09-09
1
Antibiotic susceptibility signatures identify potential antimicrobial targets in the Acinetobacter baumannii cell envelope
2020-09-09
1
Collagen promotes anti-PD-1/PD-L1 resistance in cancer through LAIR1-dependent CD8+ T cell exhaustion
2020-09-09
1
Cropland expansion in the United States produces marginal yields at high costs to wildlife
2020-09-09
1
Implicit pattern learning predicts individual differences in belief in God in the United States and Afghanistan
2020-09-09
0.92
Rapid and dynamic processing of face pareidolia in the human brain
2020-09-09
0.88
Re-imagining fMRI for awake behaving infants
2020-09-09
1
Segmented flow generator for serial crystallography at the European X-ray free electron laser
2020-09-09
0.33
Substantial underestimation of SARS-CoV-2 infection in the United States
2020-09-09
1
The neuromuscular junction is a focal point of mTORC1 signaling in sarcopenia
2020-09-09
0.11
Amalgamated cross-species transcriptomes reveal organ-specific propensity in gene expression evolution
2020-09-08
1
Circuit-specific hippocampal ΔFosB underlies resilience to stress-induced social avoidance
2020-09-08
0.94
Collectively stabilizing and orienting posterior migratory forces disperses cell clusters in vivo
2020-09-08
1
Engineering multiple species-like genetic incompatibilities in insects
2020-09-08
1
Enhancing mucosal immunity by transient microbiota depletion
2020-09-08
1
Environmental-social-economic footprints of consumption and trade in the Asia-Pacific region
2020-09-08
0.13
FastClone is a probabilistic tool for deconvoluting tumor heterogeneity in bulk-sequencing samples
2020-09-08
1
Fonio millet genome unlocks African orphan crop diversity for agriculture in a changing climate
2020-09-08
0.02
Forest carbon sink neutralized by pervasive growth-lifespan trade-offs
2020-09-08
0.07
Helicase LSH/Hells regulates kinetochore function, histone H3/Thr3 phosphorylation and centromere transcription during oocyte meiosis
2020-09-08
0.83
Intestinal microbiota-derived short-chain fatty acids regulation of immune cell IL-22 production and gut immunity
2020-09-08
0.84
Single-cell transcriptome maps of myeloid blood cell lineages in Drosophila
2020-09-08
0.19
Assembly intermediates of orthoreovirus captured in the cell
2020-09-07
0.25
Cocaine-mediated circadian reprogramming in the striatum through dopamine D2R and PPARγ activation
2020-09-07
1
Engineered systems of inducible anti-repressors for the next generation of biological programming
2020-09-07
1
Integrin-alpha-6+ Candidate stem cells are responsible for whole body regeneration in the invertebrate chordate Botrylloides diegensis
2020-09-07
1
Purification of HCC-specific extracellular vesicles on nanosubstrates for early HCC detection by digital scoring
2020-09-07
0.92
The trajectory of intrahelical lesion recognition and extrusion by the human 8-oxoguanine DNA glycosylase
2020-09-07
0.86
Transcriptomic analysis links diverse hypothalamic cell types to fibroblast growth factor 1-induced sustained diabetes remission
2020-09-07
0.53
Chromosome 1q21.2 and additional loci influence risk of spontaneous coronary artery dissection and myocardial infarction
2020-09-04
0.82
Identifying domains of applicability of machine learning models for materials science
2020-09-04
0.08
Mitochondrial CaMKII causes adverse metabolic reprogramming and dilated cardiomyopathy
2020-09-04
0.78
Pan-cancer study detects genetic risk variants and shared genetic basis in two large cohorts
2020-09-04
1
Repertoire-scale determination of class II MHC peptide binding via yeast display improves antigen prediction
2020-09-04
1
Accurate quantification of copy-number aberrations and whole-genome duplications in multi-sample tumor sequencing data
2020-09-02
1
Analysis of chromatin organization and gene expression in T cells identifies functional genes for rheumatoid arthritis
2020-09-02
0.09
Circadian control of brain glymphatic and lymphatic fluid flow
2020-09-02
0.83
Feeding-dependent tentacle development in the sea anemone Nematostella vectensis
2020-09-02
0.50
Flexible genes establish widespread bacteriophage pan-genomes in cryoconite hole ecosystems
2020-09-02
0.10
Suprachiasmatic VIP neurons are required for normal circadian rhythmicity and comprised of molecularly distinct subpopulations
2020-09-02
1
Yield reduction under climate warming varies among wheat cultivars in South Africa
2020-09-02
0.75
American mastodon mitochondrial genomes suggest multiple dispersal events in response to Pleistocene climate oscillations
2020-09-01
0.44
AmpliconReconstructor integrates NGS and optical mapping to resolve the complex structures of focal amplifications
2020-09-01
1
An orphan protein of Fusarium graminearum modulates host immunity by mediating proteasomal degradation of TaSnRK1α
2020-09-01
0.11
Dual roles of neutrophils in metastatic colonization are governed by the host NK cell status
2020-09-01
0.85
Inhibitors of BRAF dimers using an allosteric site
2020-09-01
1
Renewable energy production will exacerbate mining threats to biodiversity
2020-09-01
0.17
Representation of features as images with neighborhood dependencies for compatibility with convolutional neural networks
2020-09-01
1
Serological identification of SARS-CoV-2 infections among children visiting a hospital during the initial Seattle outbreak
2020-09-01
1
The genomic landscape of Mongolian hepatocellular carcinoma
2020-09-01
0.64
Widespread transfer of mobile antibiotic resistance genes within individual gut microbiomes revealed through bacterial Hi-C
2020-09-01
1
ABHD4-dependent developmental anoikis safeguards the embryonic brain
2020-08-31
0.35
Cardiac dopamine D1 receptor triggers ventricular arrhythmia in chronic heart failure
2020-08-31
0.15
Entropy of a bacterial stress response is a generalizable predictor for fitness and antibiotic sensitivity
2020-08-31
1
Experience-dependent resonance in amygdalo-cortical circuits supports fear memory retrieval following extinction
2020-08-31
1
Molecular layer interneurons in the cerebellum encode for valence in associative learning
2020-08-31
0.79
Plasticity of muscle synergies through fractionation and merging during development and training of human runners
2020-08-31
0.07
The cellular and molecular landscape of hypothalamic patterning and differentiation from embryonic to late postnatal development
2020-08-31
1
Unconscious reinforcement learning of hidden brain states supported by confidence
2020-08-31
0.17
Complete chemical structures of human mitochondrial tRNAs
2020-08-28
0.06
Connexin-46/50 in a dynamic lipid environment resolved by CryoEM at 1.9 Å
2020-08-28
1
Defining the ATPome reveals cross-optimization of metabolic pathways
2020-08-28
0.92
Disruption of Cav1.2-mediated signaling is a pathway for ketamine-induced pathology
2020-08-28
1
Distinct Cdk9-phosphatase switches act at the beginning and end of elongation by RNA polymerase II
2020-08-28
1
Dynamic remodelling of the human host cell proteome and phosphoproteome upon enterovirus infection
2020-08-28
0.15
Effective plans for hospital system response to earthquake emergencies
2020-08-28
0.80
Fast and multiplexed superresolution imaging with DNA-PAINT-ERS
2020-08-28
0.95
High force catch bond mechanism of bacterial adhesion in the human gut
2020-08-28
0.17
Intracellular sodium elevation reprograms cardiac metabolism
2020-08-28
0.17
Sex differences in oncogenic mutational processes
2020-08-28
0.30
Bidirectional Wnt signaling between endoderm and mesoderm confers tracheal identity in mouse and human cells
2020-08-27
0.24
Caveolin-1-mediated sphingolipid oncometabolism underlies a metabolic vulnerability of prostate cancer
2020-08-27
1
Clinically applicable histopathological diagnosis system for gastric cancer detection using deep learning
2020-08-27
0.04
Identification of osteogenic progenitor cell-targeted peptides that augment bone formation
2020-08-27
0.93
Isobutanol production freed from biological limits using synthetic biochemistry
2020-08-27
1
Lung-derived HMGB1 is detrimental for vascular remodeling of metabolically imbalanced arterial macrophages
2020-08-27
0.95
Multiplexed single-cell transcriptional response profiling to define cancer vulnerabilities and therapeutic mechanism of action
2020-08-27
0.98
RNA-binding proteins Musashi and tau soluble aggregates initiate nuclear dysfunction
2020-08-27
1
Ribosome-mediated polymerization of long chain carbon and cyclic amino acids into peptides in vitro
2020-08-27
1
Senolytics prevent mt-DNA-induced inflammation and promote the survival of aged organs following transplantation
2020-08-27
0.56
Single cell transcriptomics identifies a signaling network coordinating endoderm and mesoderm diversification during foregut organogenesis
2020-08-27
0.90
TET1 is a beige adipocyte-selective epigenetic suppressor of thermogenesis
2020-08-27
1
The dynamic landscape of transcription initiation in yeast mitochondria
2020-08-27
0.50
CFTR trafficking mutations disrupt cotranslational protein folding by targeting biosynthetic intermediates
2020-08-26
1
Enhancing intracellular accumulation and target engagement of PROTACs with reversible covalent chemistry
2020-08-26
1
Fibroblast-enriched endoplasmic reticulum protein TXNDC5 promotes pulmonary fibrosis by augmenting TGFβ signaling through TGFBR1 stabilization
2020-08-26
0.19
Structural mechanism for replication origin binding and remodeling by a metazoan origin recognition complex and its co-loader Cdc6
2020-08-26
0.50
Two-color nanoscopy of organelles for extended times with HIDE probes
2020-08-26
1
Blood substitution therapy rescues the brain of mice from ischemic damage
2020-08-25
1
Calcium-sensing receptor-mediated NLRP3 inflammasome response to calciprotein particles drives inflammation in rheumatoid arthritis
2020-08-25
0.04
Different scaling of linear models and deep learning in UKBiobank brain images versus machine-learning datasets
2020-08-25
0.25
Origin and cross-species transmission of bat coronaviruses in China
2020-08-25
0.57
Reduced serial dependence suggests deficits in synaptic potentiation in anti-NMDAR encephalitis and schizophrenia
2020-08-25
0.02
Single cell transcriptomics of human epidermis identifies basal stem cell transition states
2020-08-25
1
Use of ratiometrically designed nanocarrier targeting CDK4/6 and autophagy pathways for effective pancreatic cancer treatment
2020-08-25
0.91
A discrete serotonergic circuit regulates vulnerability to social stress
2020-08-24
0.07
Genome-wide functional analysis of phosphatases in the pathogenic fungus Cryptococcus neoformans
2020-08-24
0.06
Integrated genomic analysis reveals mutated ELF3 as a potential gallbladder cancer vaccine candidate
2020-08-24
0.38
T cell exhaustion and a failure in antigen presentation drive resistance to the graft-versus-leukemia effect
2020-08-24
1
A cross-reactive human IgA monoclonal antibody blocks SARS-CoV-2 spike-ACE2 interaction
2020-08-21
0.76
Associations between aversive learning processes and transdiagnostic psychiatric symptoms in a general population sample
2020-08-21
0.17
CORE GREML for estimating covariance between random effects in linear mixed models for complex trait analyses
2020-08-21
0.33
Continuous bioactivity-dependent evolution of an antibiotic biosynthetic pathway
2020-08-21
1
Ecological uncertainty favours the diversification of host use in avian brood parasites
2020-08-21
1
OTUD5 cooperates with TRIM25 in transcriptional regulation and tumor progression via deubiquitination activity
2020-08-21
0.13
Printable microscale interfaces for long-term peripheral nerve mapping and precision control
2020-08-21
0.83
Single cell RNA sequencing identifies early diversity of sensory neurons forming via bi-potential intermediates
2020-08-21
0.12
A pan-cancer analysis of PBAF complex mutations and their association with immunotherapy response
2020-08-20
1
An atlas of O-linked glycosylation on peptide hormones reveals diverse biological roles
2020-08-20
0.13
Evidence that the TRPV1 S1-S4 membrane domain contributes to thermosensing
2020-08-20
1
Genes with spiralian-specific protein motifs are expressed in spiralian ciliary bands
2020-08-20
1
Inhibition of inflammatory CCR2 signaling promotes aged muscle regeneration and strength recovery after injury
2020-08-20
1
Polygenic background modifies penetrance of monogenic variants for tier 1 genomic conditions
2020-08-20
1
Dead cells release a ‘necrosignal’ that activates antibiotic survival pathways in bacterial swarms
2020-08-19
1
Histone methyltransferase DOT1L coordinates AR and MYC stability in prostate cancer
2020-08-19
1
Recent declines in salmon body size impact ecosystems and fisheries
2020-08-19
0.88
The Rad53CHK1/CHK2-Spt21NPAT and Tel1ATM axes couple glucose tolerance to histone dosage and subtelomeric silencing
2020-08-19
0.17
A glycoprotein B-neutralizing antibody structure at 2.8 Å uncovers a critical domain for herpesvirus fusion initiation
2020-08-18
0.91
Gene editing and elimination of latent herpes simplex virus in vivo
2020-08-18
0.88
Influenza A virus is transmissible via aerosolized fomites
2020-08-18
1
Interaction of the pioneer transcription factor GATA3 with nucleosomes
2020-08-18
0.38
Structure and dynamics of the active Gs-coupled human secretin receptor
2020-08-18
0.20
Adaptation to the cervical environment is associated with increased antibiotic susceptibility in Neisseria gonorrhoeae
2020-08-17
0.46
CTCF-mediated chromatin looping in EGR2 regulation and SUZ12 recruitment critical for peripheral myelination and repair
2020-08-17
0.70
Cryo-EM structure of an activated VIP1 receptor-G protein complex revealed by a NanoBiT tethering strategy
2020-08-17
0.13
Demonstration of chip-based coupled degenerate optical parametric oscillators for realizing a nanophotonic spin-glass
2020-08-17
1
Deployable CRISPR-Cas13a diagnostic tools to detect and report Ebola and Lassa virus cases in real-time
2020-08-17
0.77
Enhancing chemotherapy response through augmented synthetic lethality by co-targeting nucleotide excision repair and cell-cycle checkpoints
2020-08-17
0.97
HIF-1α and HIF-2α differently regulate tumour development and inflammation of clear cell renal cell carcinoma in mice
2020-08-17
0.12
SLIT2/ROBO1-signaling inhibits macropinocytosis by opposing cortical cytoskeletal remodeling
2020-08-17
0.09
Selective inhibition of STAT3 signaling using monobodies targeting the coiled-coil and N-terminal domains
2020-08-17
0.17
Strength of immune selection in tumors varies with sex and age
2020-08-17
0.98
T-cells produce acidic niches in lymph nodes to suppress their own effector functions
2020-08-17
0.87
Widespread protein lysine acetylation in gut microbiome and its alterations in patients with Crohn’s disease
2020-08-17
0.17
Artificial intelligence for the detection of COVID-19 pneumonia on chest CT using multinational datasets
2020-08-14
0.67
BRD4 prevents the accumulation of R-loops and protects against transcription–replication collision events and DNA damage
2020-08-14
0.79
CryoEM structure of the low-complexity domain of hnRNPA2 and its conversion to pathogenic amyloid
2020-08-14
1
Disease-associated KIF3A variants alter gene methylation and expression impacting skin barrier and atopic dermatitis risk
2020-08-14
1
Ethylene-independent signaling by the ethylene precursor ACC in Arabidopsis ovular pollen tube attraction
2020-08-14
1
Genomic characterization of malignant progression in neoplastic pancreatic cysts
2020-08-14
0.49
Quantitative tRNA-sequencing uncovers metazoan tissue-specific tRNA regulation
2020-08-14
1
Scavenging of reactive dicarbonyls with 2-hydroxybenzylamine reduces atherosclerosis in hypercholesterolemic Ldlr−/− mice
2020-08-14
1
Single-cell TCR sequencing reveals phenotypically diverse clonally expanded cells harboring inducible HIV proviruses during ART
2020-08-14
0.14
Untangling the seasonal dynamics of plant-pollinator communities
2020-08-14
0.38
A high-throughput neutralizing antibody assay for COVID-19 diagnosis and vaccine evaluation
2020-08-13
0.95
Brain-inspired replay for continual learning with artificial neural networks
2020-08-13
0.83
Clearance of HIV infection by selective elimination of host cells capable of producing HIV
2020-08-13
1
Deep neural networks enable quantitative movement analysis using single-camera videos
2020-08-13
1
Development of light-responsive protein binding in the monobody non-immunoglobulin scaffold
2020-08-13
1
Elucidating the fundamental fibrotic processes driving abdominal adhesion formation
2020-08-13
1
Engineering designer beta cells with a CRISPR-Cas9 conjugation platform
2020-08-13
1
Engineering regulatory networks for complex phenotypes in E. coli
2020-08-13
0.92
FGF2 alters macrophage polarization, tumour immunity and growth and can be targeted during radiotherapy
2020-08-13
0.10
Face mask use in the general population and optimal resource allocation during the COVID-19 pandemic
2020-08-13
0.50
Identification of modified peptides using localization-aware open search
2020-08-13
1
Optogenetic control of protein binding using light-switchable nanobodies
2020-08-13
1
Pancreatic cancers suppress negative feedback of glucose transport to reprogram chromatin for metastasis
2020-08-13
1
Single-trial cross-area neural population dynamics during long-term skill learning
2020-08-13
1
Turn-on chemiluminescence probes and dual-amplification of signal for detection of amyloid beta species in vivo
2020-08-13
1
Ybx1 fine-tunes PRC2 activities to control embryonic brain development
2020-08-13
1
A fluorogenic cyclic peptide for imaging and quantification of drug-induced apoptosis
2020-08-12
0.13
Bacterial polyphosphates interfere with the innate host defense to infection
2020-08-12
0.26
Inhibition of autophagy curtails visual loss in a model of autosomal dominant optic atrophy
2020-08-12
0.15
Labile carbon limits late winter microbial activity near Arctic treeline
2020-08-12
1
Loss of NARS1 impairs progenitor proliferation in cortical brain organoids and leads to microcephaly
2020-08-12
0.53
Neural mechanisms underlying the effects of physical fatigue on effort-based choice
2020-08-12
1
Pyropia yezoensis genome reveals diverse mechanisms of carbon acquisition in the intertidal environment
2020-08-12
0.07
Blockade of the AHR restricts a Treg-macrophage suppressive axis induced by L-Kynurenine
2020-08-11
1
Efficient variance components analysis across millions of genomes
2020-08-11
1
Endogenous activity modulates stimulus and circuit-specific neural tuning and predicts perceptual behavior
2020-08-11
1
Gut microbial co-abundance networks show specificity in inflammatory bowel disease and obesity
2020-08-11
0.05
Prominent members of the human gut microbiota express endo-acting O-glycanases to initiate mucin breakdown
2020-08-11
0.19
Pupil-linked arousal signals track the temporal organization of events in memory
2020-08-11
1
Synchronization of complex human networks
2020-08-11
0.25
The genetic architecture of human brainstem structures and their involvement in common brain disorders
2020-08-11
0.02
Antibody-secreting cell destiny emerges during the initial stages of B-cell activation
2020-08-10
1
Cosmc controls B cell homing
2020-08-10
1
Developmental potential of aneuploid human embryos cultured beyond implantation
2020-08-10
0.71
Dual clumped isotope thermometry resolves kinetic biases in carbonate formation temperatures
2020-08-10
0.14
Land use and pollinator dependency drives global patterns of pollen limitation in the Anthropocene
2020-08-10
0.29
Orbitofrontal-striatal potentiation underlies cocaine-induced hyperactivity
2020-08-10
1
PD-1 pathway regulates ILC2 metabolism and PD-1 agonist treatment ameliorates airway hyperreactivity
2020-08-10
1
A neural circuit model for human sensorimotor timing
2020-08-07
1
A nonenzymatic method for cleaving polysaccharides to yield oligosaccharides for structural analysis
2020-08-07
1
ABL1-dependent OTULIN phosphorylation promotes genotoxic Wnt/β-catenin activation to enhance drug resistance in breast cancers
2020-08-07
0.73
Adolescent frontal top-down neurons receive heightened local drive to establish adult attentional behavior in mice
2020-08-07
1
Aging alters neural activity at event boundaries in the hippocampus and Posterior Medial network
2020-08-07
1
DONSON and FANCM associate with different replisomes distinguished by replication timing and chromatin domain
2020-08-07
0.60
Discovery of the cryptic function of terpene cyclases as aromatic prenyltransferases
2020-08-07
0.23
Distinct thalamocortical network dynamics are associated with the pathophysiology of chronic low back pain
2020-08-07
0.97
Enhancing myocardial repair with CardioClusters
2020-08-07
1
Epsin-mediated degradation of IP3R1 fuels atherosclerosis
2020-08-07
0.95
GWAS of thyroid stimulating hormone highlights pleiotropic effects and inverse association with thyroid cancer
2020-08-07
0.53
HNF4α regulates sulfur amino acid metabolism and confers sensitivity to methionine restriction in liver cancer
2020-08-07
0.86
Machine learning-based prediction of acute coronary syndrome using only the pre-hospital 12-lead electrocardiogram
2020-08-07
1
Multiscale causal networks identify VGF as a key regulator of Alzheimer’s disease
2020-08-07
0.98
Quantitative evaluation of protective antibody response induced by hepatitis E vaccine in humans
2020-08-07
0.16
Reversal of pre-existing NGFR-driven tumor and immune therapy resistance
2020-08-07
0.16
Single-cell analysis uncovers fibroblast heterogeneity and criteria for fibroblast and mural cell identification and discrimination
2020-08-07
0.05
Topoisomerase 1 prevents replication stress at R-loop-enriched transcription termination sites
2020-08-07
0.20
Visualizing the enzyme mechanism of mevalonate diphosphate decarboxylase
2020-08-07
1
A lung tropic AAV vector improves survival in a mouse model of surfactant B deficiency
2020-08-06
0.11
Adaptation to feedback representation of illusory orientation produced from flash grab effect
2020-08-06
0.13
An integrative multi-omics analysis to identify candidate DNA methylation biomarkers related to prostate cancer risk
2020-08-06
0.50
Auxin-induced signaling protein nanoclustering contributes to cell polarity formation
2020-08-06
0.86
Cryo-EM structures of intact V-ATPase from bovine brain
2020-08-06
1
Immune phenotyping of diverse syngeneic murine brain tumors identifies immunologically distinct types
2020-08-06
1
Nanoproteomics enables proteoform-resolved analysis of low-abundance proteins in human serum
2020-08-06
1
The REGγ inhibitor NIP30 increases sensitivity to chemotherapy in p53-deficient tumor cells
2020-08-06
0.21
The impact of the Syrian conflict on population well-being
2020-08-06
0.63
The natural function of the malaria parasite’s chloroquine resistance transporter
2020-08-06
0.10
Chemical proteomics tracks virus entry and uncovers NCAM1 as Zika virus receptor
2020-08-04
0.48
Cyclic peptide FXII inhibitor provides safe anticoagulation in a thrombosis model and in artificial lungs
2020-08-04
0.31
Evolving cooperation in multichannel games
2020-08-04
0.50
Lipo-chitooligosaccharides as regulatory signals of fungal growth and development
2020-08-04
0.63
MGMT genomic rearrangements contribute to chemotherapy resistance in gliomas
2020-08-04
0.21
Mammalian histones facilitate antimicrobial synergy by disrupting the bacterial proton gradient and chromosome organization
2020-08-04
0.78
Multiplexed Optical Sensors in Arrayed Islands of Cells for multimodal recordings of cellular physiology
2020-08-04
0.70
The inferior temporal cortex is a potential cortical precursor of orthographic processing in untrained monkeys
2020-08-04
0.80
A deep learning model to predict RNA-Seq expression of tumours from whole slide images
2020-08-03
0.86
Ancient genomes in South Patagonia reveal population movements associated with technological shifts and geography
2020-08-03
0.48
Blind spots in global soil biodiversity and ecosystem function research
2020-08-03
0.04
Engineered immunological niches to monitor disease activity and treatment efficacy in relapsing multiple sclerosis
2020-08-03
1
A neurovascular high-frequency optical coherence tomography system enables in situ cerebrovascular volumetric microscopy
2020-07-31
0.96
Anthropogenic climate change has driven over 5 million km2 of drylands towards desertification
2020-07-31
0.17
Distinct genetic architectures and environmental factors associate with host response to the γ2-herpesvirus infections
2020-07-31
0.25
European polygenic risk score for prediction of breast cancer shows similar performance in Asian women
2020-07-31
0.10
Extreme environmental conditions reduce coral reef fish biodiversity and productivity
2020-07-31
0.22
Light microscopy of proteins in their ultrastructural context
2020-07-31
1
Mapping allosteric communications within individual proteins
2020-07-31
1
Structures of the human mitochondrial ribosome bound to EF-G1 reveal distinct features of mitochondrial translation elongation
2020-07-31
1
Surface cooling caused by rare but intense near-inertial wave induced mixing in the tropical Atlantic
2020-07-31
0.14
Symmetric neural progenitor divisions require chromatin-mediated homologous recombination DNA repair by Ino80
2020-07-31
1
Testing and controlling for horizontal pleiotropy with probabilistic Mendelian randomization in transcriptome-wide association studies
2020-07-31
0.54
The suboptimality of perceptual decision making with multiple alternatives
2020-07-31
1
A molecular map of murine lymph node blood vascular endothelium at single cell resolution
2020-07-30
0.54
Collective cell mechanics of epithelial shells with organoid-like morphologies
2020-07-30
0.17
Contacting domains segregate a lipid transporter from a solute transporter in the malarial host–parasite interface
2020-07-30
1
Emerging heterogeneous compartments by viruses in single bacterial cells
2020-07-30
1
Escape from nonsense-mediated decay associates with anti-tumor immunogenicity
2020-07-30
0.15
Histone deacetylase 3 controls lung alveolar macrophage development and homeostasis
2020-07-30
1
Identification of relevant genetic alterations in cancer using topological data analysis
2020-07-30
0.73
Immunoprophylactic and immunotherapeutic control of hormone receptor-positive breast cancer
2020-07-30
0.23
Modelling the incremental benefit of introducing malaria screening strategies to antenatal care in Africa
2020-07-30
0.25
Paraventricular hypothalamus mediates diurnal rhythm of metabolism
2020-07-30
1
Purine metabolism regulates DNA repair and therapy resistance in glioblastoma
2020-07-30
0.91
STAT3 serine phosphorylation is required for TLR4 metabolic reprogramming and IL-1β expression
2020-07-30
0.13
Strategies to enable large-scale proteomics for reproducible research
2020-07-30
0.04
Structural signatures in EPR3 define a unique class of plant carbohydrate receptors
2020-07-30
0.18
Synthetic microbial communities of heterotrophs and phototrophs facilitate sustainable growth
2020-07-30
0.94
The SecA motor generates mechanical force during protein translocation
2020-07-30
1
Ultra-conformal drawn-on-skin electronics for multifunctional motion artifact-free sensing and point-of-care treatment
2020-07-30
0.97
An integrative ENCODE resource for cancer genomics
2020-07-29
0.96
Detecting sample swaps in diverse NGS data types using linkage disequilibrium
2020-07-29
1
Gradual polyploid genome evolution revealed by pan-genomic analysis of Brachypodium hybridum and its diploid progenitors
2020-07-29
0.58
Machine-learning approach expands the repertoire of anti-CRISPR protein families
2020-07-29
1
Microbiota assembly, structure, and dynamics among Tsimane horticulturalists of the Bolivian Amazon
2020-07-29
1
Molecular mechanisms underlying menthol binding and activation of TRPM8 ion channel
2020-07-29
0.14
Placebos without deception reduce self-report and neural measures of emotional distress
2020-07-29
1
The sponge effect and carbon emission mitigation potentials of the global cement cycle
2020-07-29
0.20
Transcriptional activity and strain-specific history of mouse pseudogenes
2020-07-29
0.39
Aerobic microbial life persists in oxic marine sediment as old as 101.5 million years
2020-07-28
0.13
Assembly of a patchy protein into variable 2D lattices via tunable multiscale interactions
2020-07-28
1
Mechanisms of microtubule dynamics and force generation examined with computational modeling and electron cryotomography
2020-07-28
0.67
On the natural spatio-temporal heterogeneity of South Pacific nitrous oxide
2020-07-28
1
Plasma levels of DPP4 activity and sDPP4 are dissociated from inflammation in mice and humans
2020-07-28
0.25
Comprehensive molecular comparison of hypermethylated and mutated triple negative breast cancers
2020-07-27
0.01
Coupling of 5S RNP rotation with maturation of functional centers during large ribosomal subunit assembly
2020-07-27
0.57
Directional translocation resistance of Zika xrRNA
2020-07-27
0.08
Knockout of reactive astrocyte activating factors slows disease progression in an ALS mouse model
2020-07-27
1
Mechanisms of activation and desensitization of full-length glycine receptor in lipid nanodiscs
2020-07-27
0.71
Molecular determinants for dsDNA translocation by the transcription-repair coupling and evolvability factor Mfd
2020-07-27
1
Molecular engineering of safe and efficacious oral basal insulin
2020-07-27
0.07
Preferential inhibition of adaptive immune system dynamics by glucocorticoids in patients after acute surgical trauma
2020-07-27
0.86
Prior vaccination with rVSV-ZEBOV does not interfere with but improves efficacy of postexposure antibody treatment
2020-07-27
0.92
Tracing animal genomic evolution with the chromosomal-level assembly of the freshwater sponge Ephydatia muelleri
2020-07-27
0.18
VoPo leverages cellular heterogeneity for predictive modeling of single-cell data
2020-07-27
0.99
Accounting for diverse evolutionary forces reveals mosaic patterns of selection on human preterm birth loci
2020-07-24
1
Combining PARP with ATR inhibition overcomes PARP inhibitor and platinum resistance in ovarian cancer models
2020-07-24
1
Copper bioavailability is a KRAS-specific vulnerability in colorectal cancer
2020-07-24
0.11
DNA sequence-dependent activity and base flipping mechanisms of DNMT1 regulate genome-wide DNA methylation
2020-07-24
0.33
Differential expression of tissue-restricted antigens among mTEC is associated with distinct autoreactive T cell fates
2020-07-24
0.17
Mitochondrial dynamics quantitatively revealed by STED nanoscopy with an enhanced squaraine variant probe
2020-07-24
0.07
Spinal cord injury causes chronic bone marrow failure
2020-07-24
1
Structural basis of RNA cap modification by SARS-CoV-2
2020-07-24
1
The unified myofibrillar matrix for force generation in muscle
2020-07-24
1
Astrocytes modulate sensory-evoked neuronal network activity
2020-07-23
0.60
Gasdermin-D-dependent IL-1α release from microglia promotes protective immunity during chronic Toxoplasma gondii infection
2020-07-23
1
Microbial diversity drives carbon use efficiency in a model soil
2020-07-23
1
Mutations in FAM50A suggest that Armfield XLID syndrome is a spliceosomopathy
2020-07-23
0.57
Structural mechanism for gating of a eukaryotic mechanosensitive channel of small conductance
2020-07-23
1
Mimicry of emergent traits amplifies coastal restoration success
2020-07-22
0.14
Multi-faceted epigenetic dysregulation of gene expression promotes esophageal squamous cell carcinoma
2020-07-22
0.40
Murine models of IDH-wild-type glioblastoma exhibit spatial segregation of tumor initiation and manifestation during evolution
2020-07-22
1
Rapid, deep and precise profiling of the plasma proteome with multi-nanoparticle protein corona
2020-07-22
1
A global lipid map defines a network essential for Zika virus replication
2020-07-21
0.87
Majority sensing in synthetic microbial consortia
2020-07-21
0.86
Mitochondrial respiration controls neoangiogenesis during wound healing and tumour growth
2020-07-21
0.05
Non-invasive early detection of cancer four years before conventional diagnosis using a blood test
2020-07-21
0.27
South-to-North Water Diversion stabilizing Beijing’s groundwater levels
2020-07-21
0.17
Basement membrane damage by ROS- and JNK-mediated Mmp2 activation drives macrophage recruitment to overgrown tissue
2020-07-20
1
Landscape of somatic single nucleotide variants and indels in colorectal cancer and impact on survival
2020-07-20
0.56
Magnetic field boosted ferroptosis-like cell death and responsive MRI using hybrid vesicles for cancer immunotherapy
2020-07-20
1
Mutations in COMP cause familial carpal tunnel syndrome
2020-07-20
0.26
PDZD8 interacts with Protrudin and Rab7 at ER-late endosome membrane contact sites associated with mitochondria
2020-07-20
0.33
Proteome activity landscapes of tumor cell lines determine drug responses
2020-07-20
0.03
3D genome organization contributes to genome instability at fragile sites
2020-07-17
0.56
A rare variant of African ancestry activates 8q24 lncRNA hub by modulating cancer associated enhancer
2020-07-17
0.21
Accelerated single cell seeding in relapsed multiple myeloma
2020-07-17
1
An FGF15/19-TFEB regulatory loop controls hepatic cholesterol and bile acid homeostasis
2020-07-17
1
Calcium isotopic ecology of Turkana Basin hominins
2020-07-17
0.20
Engineered CRISPR/Cas9 enzymes improve discrimination by slowing DNA cleavage to allow release of off-target DNA
2020-07-17
1
Exhausted T cell signature predicts immunotherapy response in ER-positive breast cancer
2020-07-17
1
Global translation during early development depends on the essential transcription factor PRDM10
2020-07-17
0.05
MG53 suppresses interferon-β and inflammation via regulation of ryanodine receptor-mediated intracellular calcium signaling
2020-07-17
1
Real-time 3D single molecule tracking
2020-07-17
1
Using sigLASSO to optimize cancer mutation signatures jointly with sampling likelihood
2020-07-17
1
Alveolar regeneration through a Krt8+ transitional stem cell state that persists in human lung fibrosis
2020-07-16
0.21
Disruption of the tumour-associated EMP3 enhances erythroid proliferation and causes the MAM-negative phenotype
2020-07-16
0.08
Dissemination of RasV12-transformed cells requires the mechanosensitive channel Piezo
2020-07-16
1
Distributed and retinotopically asymmetric processing of coherent motion in mouse visual cortex
2020-07-16
1
Machine learning of serum metabolic patterns encodes early-stage lung adenocarcinoma
2020-07-16
0.07
The Bartonella autotransporter BafA activates the host VEGF pathway to drive angiogenesis
2020-07-16
0.04
Unexpected complexity of everyday manual behaviors
2020-07-16
1
A STING-based biosensor affords broad cyclic dinucleotide detection within single living eukaryotic cells
2020-07-15
1
Blood genome expression profiles in infants with congenital cytomegalovirus infection
2020-07-15
0.92
Co-option of Plasmodium falciparum PP1 for egress from host erythrocytes
2020-07-15
0.60
ITLN1 modulates invasive potential and metabolic reprogramming of ovarian cancer cells in omental microenvironment
2020-07-15
1
Ornithine-A urea cycle metabolite enhances autophagy and controls Mycobacterium tuberculosis infection
2020-07-15
1
Rieske iron-sulfur protein induces FKBP12.6/RyR2 complex remodeling and subsequent pulmonary hypertension through NF-κB/cyclin D1 pathway
2020-07-15
0.91
Tumor response and endogenous immune reactivity after administration of HER2 CAR T cells in a child with metastatic rhabdomyosarcoma
2020-07-15
0.96
A perceptual scaling approach to eyewitness identification
2020-07-14
1
Analysis of compositions of microbiomes with bias correction
2020-07-14
1
Avoiding dynastic, assortative mating, and population stratification biases in Mendelian randomization through within-family analyses
2020-07-14
0.26
HIV-1 replication complexes accumulate in nuclear speckles and integrate into speckle-associated genomic domains
2020-07-14
1
In vivo microscopy reveals macrophage polarization locally promotes coherent microtubule dynamics in migrating cancer cells
2020-07-14
1
Oculomotor inhibition precedes temporally expected auditory targets
2020-07-14
0.20
PRDM15 is a key regulator of metabolism critical to sustain B-cell lymphomagenesis
2020-07-14
0.18
Spatial domain analysis predicts risk of colorectal cancer recurrence and infers associated tumor microenvironment networks
2020-07-14
1
Substrate regulation leads to differential responses of microbial ammonia-oxidizing communities to ocean warming
2020-07-14
0.13
Understanding the genetic determinants of the brain with MOSTest
2020-07-14
0.31
Zika virus vertical transmission in children with confirmed antenatal exposure
2020-07-14
0.46
Contextual fear memory retrieval by correlated ensembles of ventral CA1 neurons
2020-07-13
1
Epigenetic homogeneity in histone methylation underlies sperm programming for embryonic transcription
2020-07-13
0.11
High-performance CRISPR-Cas12a genome editing for combinatorial genetic screening
2020-07-13
1
The choline transporter Slc44a2 controls platelet activation and thrombosis by regulating mitochondrial function
2020-07-13
0.95
A cytoskeleton regulator AVIL drives tumorigenesis in glioblastoma
2020-07-10
0.86
A general approach to engineer positive-going eFRET voltage indicators
2020-07-10
1
A second generation leishmanization vaccine with a markerless attenuated Leishmania major strain using CRISPR gene editing
2020-07-10
0.79
Cryo-EM structure of catalytic ribonucleoprotein complex RNase MRP
2020-07-10
1
Gainers and losers of surface and terrestrial water resources in China during 1989–2016
2020-07-10
0.39
Mnemonic prediction errors bias hippocampal states
2020-07-10
0.67
NMDAR-mediated modulation of gap junction circuit regulates olfactory learning in C. elegans
2020-07-10
1
Nuclear moonlighting of cytosolic glyceraldehyde-3-phosphate dehydrogenase regulates Arabidopsis response to heat stress
2020-07-10
1
Phasic dopamine reinforces distinct striatal stimulus encoding in the olfactory tubercle driving dopaminergic reward prediction
2020-07-10
0.10
Raman image-activated cell sorting
2020-07-10
0.04
Value and choice as separable and stable representations in orbitofrontal cortex
2020-07-10
1
Water rights shape crop yield and revenue volatility tradeoffs for adaptation in snow dependent systems
2020-07-10
1
Within-host microevolution of Streptococcus pneumoniae is rapid and adaptive during natural colonisation
2020-07-10
0.16
A supervised learning framework for chromatin loop detection in genome-wide contact maps
2020-07-09
1
Antisense oligonucleotide modulation of non-productive alternative splicing upregulates gene expression
2020-07-09
1
Biased belief updating and suboptimal choice in foraging decisions
2020-07-09
0.83
The chromatin remodeling enzyme Chd4 regulates genome architecture in the mouse brain
2020-07-09
0.96
The structures of two archaeal type IV pili illuminate evolutionary relationships
2020-07-09
0.57
Cholesterol metabolism drives regulatory B cell IL-10 through provision of geranylgeranyl pyrophosphate
2020-07-08
0.22
κB-Ras and Ral GTPases regulate acinar to ductal metaplasia during pancreatic adenocarcinoma development and pancreatitis
2020-07-08
0.09
A nanotrap improves survival in severe sepsis by attenuating hyperinflammation
2020-07-07
1
A user guide for the online exploration and visualization of PCAWG data
2020-07-07
0.31
Cryo-EM structure of arabinosyltransferase EmbB from Mycobacterium smegmatis
2020-07-07
0.65
Discovery and population genomics of structural variation in a songbird genus
2020-07-07
0.17
Enhancer and super-enhancer dynamics in repair after ischemic acute kidney injury
2020-07-07
0.77
IgCaller for reconstructing immunoglobulin gene rearrangements and oncogenic translocations from whole-genome sequencing in lymphoid neoplasms
2020-07-07
0.02
Interferon-independent STING signaling promotes resistance to HSV-1 in vivo
2020-07-07
1
Jawsamycin exhibits in vivo antifungal properties by inhibiting Spt14/Gpi3-mediated biosynthesis of glycosylphosphatidylinositol
2020-07-07
0.20
Pathogenic ARH3 mutations result in ADP-ribose chromatin scars during DNA strand break repair
2020-07-07
0.14
R-loop induced G-quadruplex in non-template promotes transcription by successive R-loop formation
2020-07-07
1
Roads as a contributor to landscape-scale variation in bird communities
2020-07-07
0.10
A genome-wide cross-phenotype meta-analysis of the association of blood pressure with migraine
2020-07-06
0.36
Requirements for the differentiation of innate T-bethigh memory-phenotype CD4+ T lymphocytes under steady state
2020-07-06
0.58
Uncovering mutation-specific morphogenic phenotypes and paracrine-mediated vessel dysfunction in a biomimetic vascularized mammary duct platform
2020-07-06
1
A sequential methodology for the rapid identification and characterization of breast cancer-associated functional SNPs
2020-07-03
0.83
A yeast platform for high-level synthesis of tetrahydroisoquinoline alkaloids
2020-07-03
0.38
An ecological framework to understand the efficacy of fecal microbiota transplantation
2020-07-03
0.53
Antagonistic odor interactions in olfactory sensory neurons are widespread in freely breathing mice
2020-07-03
0.75
Assessment of polygenic architecture and risk prediction based on common variants across fourteen cancers
2020-07-03
0.57
C9orf72 arginine-rich dipeptide repeats inhibit UPF1-mediated RNA decay via translational repression
2020-07-03
1
Characterization of an alternative BAK-binding site for BH3 peptides
2020-07-03
0.27
Comprehensive structure-function characterization of DNMT3B and DNMT3A reveals distinctive de novo DNA methylation mechanisms
2020-07-03
0.70
Diamond Blackfan anemia is mediated by hyperactive Nemo-like kinase
2020-07-03
0.60
Dietary glutamine supplementation suppresses epigenetically-activated oncogenic pathways to inhibit melanoma tumour growth
2020-07-03
1
Diverse interactions and ecosystem engineering can stabilize community assembly
2020-07-03
0.32
Dual RNA-seq of Orientia tsutsugamushi informs on host-pathogen interactions for this neglected intracellular human pathogen
2020-07-03
0.18
Engineering monocyte/macrophage−specific glucocerebrosidase expression in human hematopoietic stem cells using genome editing
2020-07-03
0.88
Fast three-color single-molecule FRET using statistical inference
2020-07-03
1
Intellectual disability-associated UNC80 mutations reveal inter-subunit interaction and dendritic function of the NALCN channel complex
2020-07-03
1
Long-term droughts may drive drier tropical forests towards increased functional, taxonomic and phylogenetic homogeneity
2020-07-03
0.07
Low thermal conductivity of iron-silicon alloys at Earth’s core conditions with implications for the geodynamo
2020-07-03
0.48
Mapping effector genes at lupus GWAS loci using promoter Capture-C in follicular helper T cells
2020-07-03
1
Mechanistic insights into chromatin targeting by leukemic NUP98-PHF23 fusion
2020-07-03
1
Megaevolutionary dynamics and the timing of evolutionary innovation in reptiles
2020-07-03
0.50
NCLX prevents cell death during adrenergic activation of the brown adipose tissue
2020-07-03
0.60
Oculomotor freezing reflects tactile temporal expectation and aids tactile perception
2020-07-03
0.75
Pancreatic circulating tumor cell profiling identifies LIN28B as a metastasis driver and drug target
2020-07-03
1
Persistent telomere cohesion protects aged cells from premature senescence
2020-07-03
1
Predicting and affecting response to cancer therapy based on pathway-level biomarkers
2020-07-03
0.23
Progressive nitrogen limitation across the Tibetan alpine permafrost region
2020-07-03
0.07
Rationally inattentive intertemporal choice
2020-07-03
1
Recent accelerated diversification in rosids occurred outside the tropics
2020-07-03
0.76
Silencing hepatic MCJ attenuates non-alcoholic fatty liver disease (NAFLD) by increasing mitochondrial fatty acid oxidation
2020-07-03
0.38
Structural insight into mitochondrial β-barrel outer membrane protein biogenesis
2020-07-03
0.72
TMEM16K is an interorganelle regulator of endosomal sorting
2020-07-03
1
The RNA quality control pathway nonsense-mediated mRNA decay targets cellular and viral RNAs to restrict KSHV
2020-07-03
1
The ataxin-1 interactome reveals direct connection with multiple disrupted nuclear transport pathways
2020-07-03
0.40
The induction and function of the anti-inflammatory fate of TH17 cells
2020-07-03
0.42
Transcriptomic and cellular decoding of regional brain vulnerability to neurogenetic disorders
2020-07-03
0.52
A FAK/HDAC5 signaling axis controls osteocyte mechanotransduction
2020-07-01
1
Structural characterization of a novel human adeno-associated virus capsid with neurotropic properties
2020-06-30
0.87
Long-term culture of human pancreatic slices as a model to study real-time islet regeneration
2020-06-29
0.93
MetaRibo-Seq measures translation in microbiomes
2020-06-29
1
Proximity labeling proteomics reveals critical regulators for inner nuclear membrane protein degradation in plants
2020-06-29
0.38
Quantifying molecular bias in DNA data storage
2020-06-29
1
Elastomeric polyamide biomaterials with stereochemically tuneable mechanical properties and shape memory
2020-06-26
0.22
Exploiting metabolic acidosis in solid cancers using a tumor-agnostic pH-activatable nanoprobe for fluorescence-guided surgery
2020-06-26
0.27
Prolonged tau clearance and stress vulnerability rescue by pharmacological activation of autophagy in tauopathy neurons
2020-06-26
0.80
Protein arginine deiminase 4 antagonizes methylglyoxal-induced histone glycation
2020-06-26
1
Reduced neural selectivity for mental states in deaf children with delayed exposure to sign language
2020-06-26
1
Spermine synthase and MYC cooperate to maintain colorectal cancer cell survival by repressing Bim expression
2020-06-26
0.90
Systemic nanoparticle delivery of CRISPR-Cas9 ribonucleoproteins for effective tissue specific genome editing
2020-06-26
1
Turning induced plasticity into refined adaptations during range expansion
2020-06-26
1
Uncovering the effects of interface-induced ordering of liquid on crystal growth using machine learning
2020-06-26
1
miR-181a initiates and perpetuates oncogenic transformation through the regulation of innate immune signaling
2020-06-26
1
Extreme rainfall events alter the trophic structure in bromeliad tanks across the Neotropics
2020-06-25
0.11
The cryo-EM structure of the bacterial flagellum cap complex suggests a molecular mechanism for filament elongation
2020-06-25
0.29
The lncRNA lincNMR regulates nucleotide metabolism via a YBX1 - RRM2 axis in cancer
2020-06-25
0.50
Durable protection against repeated penile exposures to simian-human immunodeficiency virus by broadly neutralizing antibodies
2020-06-24
1
Genome-wide association meta-analysis identifies GP2 gene risk variants for pancreatic cancer
2020-06-24
0.09
Identification of distinct loci for de novo DNA methylation by DNMT3A and DNMT3B during mammalian development
2020-06-24
0.06
Oncolytic virus-derived type I interferon restricts CAR T cell therapy
2020-06-24
0.90
Phosphodiesterase-5 inhibitors use and risk for mortality and metastases among male patients with colorectal cancer
2020-06-24
0.13
Protease-activation using anti-idiotypic masks enables tumor specificity of a folate receptor 1-T cell bispecific antibody
2020-06-24
0.10
Structural plasticity of SARS-CoV-2 3CL Mpro active site cavity revealed by room temperature X-ray crystallography
2020-06-24
1
Synergism between IL7R and CXCR4 drives BCR-ABL induced transformation in Philadelphia chromosome-positive acute lymphoblastic leukemia
2020-06-24
0.10
The role of mPFC and MTL neurons in human choice under goal-conflict
2020-06-24
0.03
mTOR and S6K1 drive polycystic kidney by the control of Afadin-dependent oriented cell division
2020-06-24
0.11
Contribution of land use to the interannual variability of the land carbon cycle
2020-06-23
0.50
Diaphanous-related formin mDia2 regulates beta2 integrins to control hematopoietic stem and progenitor cell engraftment
2020-06-23
1
Endothelial activation of caspase-9 promotes neurovascular injury in retinal vein occlusion
2020-06-23
1
Fasting mimicking diet as an adjunct to neoadjuvant chemotherapy for breast cancer in the multicentre randomized phase 2 DIRECT trial
2020-06-23
0.02
The mutREAD method detects mutational signatures from low quantities of cancer DNA
2020-06-23
0.07
Ultra-large chemical libraries for the discovery of high-affinity peptide binders
2020-06-23
0.56
Using arterial–venous analysis to characterize cancer metabolic consumption in patients
2020-06-23
0.45
Widespread transcript shortening through alternative polyadenylation in secretory cell differentiation
2020-06-23
1
DNA double-strand breaks induce H2Ax phosphorylation domains in a contact-dependent manner
2020-06-22
1
Meningeal lymphatics clear erythrocytes that arise from subarachnoid hemorrhage
2020-06-22
0.08
Structural mechanism underlying primary and secondary coupling between GPCRs and the Gi/o family
2020-06-22
0.14
Structure of the polymerase ε holoenzyme and atomic model of the leading strand replisome
2020-06-22
1
A dietary fatty acid counteracts neuronal mechanical sensitization
2020-06-19
1
A missense mutation in the MLKL brace region promotes lethal neonatal inflammation and hematopoietic dysfunction
2020-06-19
0.08
Distinct pseudokinase domain conformations underlie divergent activation mechanisms among vertebrate MLKL orthologues
2020-06-19
0.12
Heterogeneously integrated flexible microwave amplifiers on a cellulose nanofibril substrate
2020-06-19
0.97
High flavivirus structural plasticity demonstrated by a non-spherical morphological variant
2020-06-19
0.06
Holistic engineering of cell-free systems through proteome-reprogramming synthetic circuits
2020-06-19
0.71
Jellyfish genomes reveal distinct homeobox gene clusters and conservation of small RNA processing
2020-06-19
0.05
MeCP2 regulates gene expression through recognition of H3K27me3
2020-06-19
0.20
Mutually stabilizing interactions between proto-peptides and RNA
2020-06-19
1
Nolz1 expression is required in dopaminergic axon guidance and striatal innervation
2020-06-19
0.31
Non-cooperative 4E-BP2 folding with exchange between eIF4E-binding and binding-incompatible states tunes cap-dependent translation inhibition
2020-06-19
0.05
Profiling immunoglobulin repertoires across multiple human tissues using RNA sequencing
2020-06-19
0.86
Repurposing type I–F CRISPR–Cas system as a transcriptional activation tool in human cells
2020-06-19
0.12
Structural basis of host protein hijacking in human T-cell leukemia virus integration
2020-06-19
1
The Archaeal Proteome Project advances knowledge about archaeal cell biology through comprehensive proteomics
2020-06-19
0.26
Topoisomerase 3β knockout mice show transcriptional and behavioural impairments associated with neurogenesis and synaptic plasticity
2020-06-19
1
Bone marrow adipose tissue is a unique adipose subtype with distinct roles in glucose homeostasis
2020-06-18
0.07
Genetic breakdown of a Tet-off conditional lethality system for insect population control
2020-06-18
0.50
Globalization and the rise and fall of cognitive control
2020-06-18
1
Harmonization of quality metrics and power calculation in multi-omic studies
2020-06-18
0.22
Proline-rich protein PRR19 functions with cyclin-like CNTD1 to promote meiotic crossing over in mouse
2020-06-18
0.22
Specificity of end resection pathways for double-strand break regions containing ribonucleotides and base lesions
2020-06-18
1
The genomic and epigenomic evolutionary history of papillary renal cell carcinomas
2020-06-18
0.65
Meta-analysis of the impacts of global change factors on soil microbial diversity and functionality
2020-06-17
0.33
The integrated genomic and epigenomic landscape of brainstem glioma
2020-06-17
0.31
p53 destabilizing protein skews asymmetric division and enhances NOTCH activation to direct self-renewal of TICs
2020-06-17
1
Hepatic HuR modulates lipid homeostasis in response to high-fat diet
2020-06-16
0.17
Motion corrected MRI differentiates male and female human brain growth trajectories from mid-gestation
2020-06-16
1
Recurrent horizontal transfer identifies mitochondrial positive selection in a transmissible cancer
2020-06-16
0.08
Spatial planning with long visual range benefits escape from visual predators in complex naturalistic environments
2020-06-16
1
A constricted opening in Kir channels does not impede potassium conduction
2020-06-15
0.07
A self-sustaining endocytic-based loop promotes breast cancer plasticity leading to aggressiveness and pro-metastatic behavior
2020-06-15
0.05
Atomic-resolution mapping of transcription factor-DNA interactions by femtosecond laser crosslinking and mass spectrometry
2020-06-15
0.06
Aβ(1-42) tetramer and octamer structures reveal edge conductivity pores as a mechanism for membrane damage
2020-06-15
0.27
BAP1 is a haploinsufficient tumor suppressor linking chronic pancreatitis to pancreatic cancer in mice
2020-06-15
1
Characterization of a pluripotent stem cell-derived matrix with powerful osteoregenerative capabilities
2020-06-15
0.94
DG–CA3 circuitry mediates hippocampal representations of latent information
2020-06-15
0.25
Dual Role of WISP1 in maintaining glioma stem cells and tumor-supportive macrophages in glioblastoma
2020-06-15
1
Early stratification of radiotherapy response by activatable inflammation magnetic resonance imaging
2020-06-15
0.79
Multimodal network dynamics underpinning working memory
2020-06-15
1
Rab11b-mediated integrin recycling promotes brain metastatic adaptation and outgrowth
2020-06-15
1
Structural basis for chemokine receptor CCR6 activation by the endogenous protein ligand CCL20
2020-06-15
1
A kinase-deficient NTRK2 splice variant predominates in glioma and amplifies several oncogenic signaling pathways
2020-06-12
0.81
ARS2/MAGL signaling in glioblastoma stem cells promotes self-renewal and M2-like polarization of tumor-associated macrophages
2020-06-12
0.09
Adipocyte G signaling is essential for maintaining whole-body glucose homeostasis and insulin sensitivity
2020-06-12
1
Angiopoietin-2–integrin α5β1 signaling enhances vascular fatty acid transport and prevents ectopic lipid-induced insulin resistance
2020-06-12
0.10
Autophagy controls the induction and developmental decline of NMDAR-LTD through endocytic recycling
2020-06-12
0.85
CRISPR artificial splicing factors
2020-06-12
1
Clonal hematopoiesis is associated with adverse outcomes in multiple myeloma patients undergoing transplant
2020-06-12
0.98
Dynamic and scalable DNA-based information storage
2020-06-12
1
Functional annotation of rare structural variation in the human brain
2020-06-12
0.94
Quantification of ongoing APOBEC3A activity in tumor cells by monitoring RNA editing at hotspots
2020-06-12
1
Robust leaf trait relationships across species under global environmental changes
2020-06-12
0.25
Sociality and interaction envelope organize visual action representations
2020-06-12
1
Structural basis for divergent C–H hydroxylation selectivity in two Rieske oxygenases
2020-06-12
1
Sub-nanowatt resolution direct calorimetry for probing real-time metabolic activity of individual C. elegans worms
2020-06-12
1
Targeted inhibition of activated protein C by a non-active-site inhibitory antibody to treat hemophilia
2020-06-12
0.57
Autophagy-mediated apoptosis eliminates aneuploid cells in a mouse model of chromosome mosaicism
2020-06-11
0.13
Diagnostic evaluation of a deep learning model for optical diagnosis of colorectal cancer
2020-06-11
0.04
Identification of interferon-stimulated genes that attenuate Ebola virus infection
2020-06-11
0.81
MCM8IP activates the MCM8-9 helicase to promote DNA synthesis and homologous recombination upon DNA damage
2020-06-11
0.80
Modular self-assembly of gamma-modified peptide nucleic acids in organic solvent mixtures
2020-06-11
1
Norovirus infection causes acute self-resolving diarrhea in wild-type neonatal mice
2020-06-11
1
Transfer functions linking neural calcium to single voxel functional ultrasound signal
2020-06-11
0.20
A cancer drug atlas enables synergistic targeting of independent drug vulnerabilities
2020-06-10
0.15
An iron (II) dependent oxygenase performs the last missing step of plant lysine catabolism
2020-06-10
0.98
Discovery and quality analysis of a comprehensive set of structural variants and short tandem repeats
2020-06-10
0.71
Impaired peroxisomal import in Drosophila oenocytes causes cardiac dysfunction by inducing upd3 as a peroxikine
2020-06-10
0.78
Overcoming evanescent field decay using 3D-tapered nanocavities for on-chip targeted molecular analysis
2020-06-10
0.96
Properties of structural variants and short tandem repeats associated with gene expression and complex traits
2020-06-10
0.73
mTADA is a framework for identifying risk genes from de novo mutations in multiple traits
2020-06-10
1
ADP binding by the Culex quinquefasciatus mosquito D7 salivary protein enhances blood feeding on mammals
2020-06-09
1
Dicer-like 5 deficiency confers temperature-sensitive male sterility in maize
2020-06-09
1
Multiplexed imaging of nucleome architectures in single cells of mammalian tissue
2020-06-09
1
Nucleoid remodeling during environmental adaptation is regulated by HU-dependent DNA bundling
2020-06-09
1
Quantifying the drivers and predictability of seasonal changes in African fire
2020-06-09
1
Ribosome engineering reveals the importance of 5S rRNA autonomy for ribosome assembly
2020-06-09
0.83
Structural basis for oligoclonal T cell recognition of a shared p53 cancer neoantigen
2020-06-09
0.93
The genetic basis of sex determination in grapes
2020-06-09
0.92
Adaptive reduction of male gamete number in the selfing plant Arabidopsis thaliana
2020-06-08
0.04
Animal biosynthesis of complex polyketides in a photosynthetic partnership
2020-06-08
1
Marriage of black phosphorus and Cu2+ as effective photothermal agents for PET-guided combination cancer therapy
2020-06-08
0.34
Mechanism of effector capture and delivery by the type IV secretion system from Legionella pneumophila
2020-06-08
0.31
NAP1-RELATED PROTEIN1 and 2 negatively regulate H2A.Z abundance in chromatin in Arabidopsis
2020-06-08
0.45
Transcriptional and imaging-genetic association of cortical interneurons, brain function, and schizophrenia risk
2020-06-08
1
Global correlates of range contractions and expansions in terrestrial mammals
2020-06-05
0.06
MYC functions as a switch for natural killer cell-mediated immune surveillance of lymphoid malignancies
2020-06-05
1
Multi-trait analysis of rare-variant association summary statistics using MTAR
2020-06-05
1
Mutational bias and the protein code shape the evolution of splicing enhancers
2020-06-05
1
Robust dynamic community detection with applications to human brain functional networks
2020-06-05
1
Systemic lupus erythematosus favors the generation of IL-17 producing double negative T cells
2020-06-05
1
Transcriptomics and proteomics reveal a cooperation between interferon and T-helper 17 cells in neuromyelitis optica
2020-06-05
0.74
Visualizing group II intron dynamics between the first and second steps of splicing
2020-06-05
0.25
m5C modification of mRNA serves a DNA damage code to promote homologous recombination
2020-06-05
1
An essential role for Argonaute 2 in EGFR-KRAS signaling in pancreatic cancer development
2020-06-04
1
Effects of nonequilibrium fluctuations on ultrafast short-range electron transfer dynamics
2020-06-04
0.83
Human aminolevulinate synthase structure reveals a eukaryotic-specific autoinhibitory loop regulating substrate binding and product release
2020-06-04
0.33
Invasion of vaginal epithelial cells by uropathogenic Escherichia coli
2020-06-04
1
Liquid-liquid phase separation induces pathogenic tau conformations in vitro
2020-06-04
1
Natural variations at the Stay-Green gene promoter control lifespan and yield in rice cultivars
2020-06-04
0.09
SIRT1 accelerates the progression of activity-based anorexia
2020-06-04
0.70
Activation of JUN in fibroblasts promotes pro-fibrotic programme and modulates protective immunity
2020-06-03
0.90
Fires prime terrestrial organic carbon for riverine export to the global oceans
2020-06-03
0.14
In situ conversion of defective Treg into SuperTreg cells to treat advanced IPEX-like disorders in mice
2020-06-03
0.13
Independent regulation of age associated fat accumulation and longevity
2020-06-03
1
Labeled oxytocin administered via the intranasal route reaches the brain in rhesus macaques
2020-06-03
1
Perceptual fusion of musical notes by native Amazonians suggests universal representations of musical intervals
2020-06-03
0.56
Polyamine regulation of ion channel assembly and implications for nicotinic acetylcholine receptor pharmacology
2020-06-03
1
RSPO3 impacts body fat distribution and regulates adipose cell biology in vitro
2020-06-03
0.10
Single-cell transcriptomic analysis identifies the conversion of zebrafish Etv2-deficient vascular progenitors into skeletal muscle
2020-06-03
1
The characterization of Mediator 12 and 13 as conditional positive gene regulators in Arabidopsis
2020-06-03
0.85
The transcriptional repressor Blimp1/PRDM1 regulates the maternal decidual response in mice
2020-06-03
0.25
Traceless native chemical ligation of lipid-modified peptide surfactants by mixed micelle formation
2020-06-03
1
Ultrasmall copper-based nanoparticles for reactive oxygen species scavenging and alleviation of inflammation related diseases
2020-06-03
0.09
A hypomorphic gene contributes to cavefish eye loss by disrupting optic vasculature
2020-06-02
1
AGO-bound mature miRNAs are oligouridylated by TUTs and subsequently degraded by DIS3L2
2020-06-02
0.83
Cellular census of human fibrosis defines functionally distinct stromal cell types and states
2020-06-02
0.15
Cephalopod-inspired optical engineering of human cells
2020-06-02
0.92
Durable and controlled depletion of neutrophils in mice
2020-06-02
0.19
Human beige adipocytes for drug discovery and cell therapy in metabolic diseases
2020-06-02
1
Human norovirus targets enteroendocrine epithelial cells in the small intestine
2020-06-02
1
Loss of the transcription factor MAFB limits β-cell derivation from human PSCs
2020-06-02
1
Modeling mitigation of influenza epidemics by baloxavir
2020-06-02
1
Multiplexed relative and absolute quantitative immunopeptidomics reveals MHC I repertoire alterations induced by CDK4/6 inhibition
2020-06-02
1
Plasma-derived extracellular vesicles from Plasmodium vivax patients signal spleen fibroblasts via NF-kB facilitating parasite cytoadherence
2020-06-02
0.06
Quantifying CDK inhibitor selectivity in live cells
2020-06-02
0.88
Rapid range shifts and megafaunal extinctions associated with late Pleistocene climate change
2020-06-02
0.69
Role of serotonergic dorsal raphe neurons in hypercapnia-induced arousals
2020-06-02
1
The ABCG2 Q141K hyperuricemia and gout associated variant illuminates the physiology of human urate excretion
2020-06-02
0.42
The impact of climate and antigenic evolution on seasonal influenza virus epidemics in Australia
2020-06-02
0.20
The impact of learning on perceptual decisions and its implication for speed-accuracy tradeoffs
2020-06-02
0.17
Type I interferon sensing unlocks dormant adipocyte inflammatory potential
2020-06-02
1
Visualizable detection of nanoscale objects using anti-symmetric excitation and non-resonance amplification
2020-06-02
1
A genome-wide gain-of-function screen identifies CDKN2C as a HBV host factor
2020-06-01
0.22
AcrIF9 tethers non-sequence specific dsDNA to the CRISPR RNA-guided surveillance complex
2020-06-01
0.75
An evolutionary path to altered cofactor specificity in a metalloenzyme
2020-06-01
0.17
Chronic expression of p16INK4a in the epidermis induces Wnt-mediated hyperplasia and promotes tumor initiation
2020-06-01
0.07
Co-evolution of primitive methane-cycling ecosystems and early Earth’s atmosphere and climate
2020-06-01
0.27
Controls on surface water carbonate chemistry along North American ocean margins
2020-06-01
0.75
Defective NADPH production in mitochondrial disease complex I causes inflammation and cell death
2020-06-01
1
Dynamics of the 4D genome during in vivo lineage specification and differentiation
2020-06-01
0.13
Functional reconstruction of injured corpus cavernosa using 3D-printed hydrogel scaffolds seeded with HIF-1α-expressing stem cells
2020-06-01
0.15
Immunotherapy with engineered bacteria by targeting the STING pathway for anti-tumor immunity
2020-06-01
1
Improving the safety of human pluripotent stem cell therapies using genome-edited orthogonal safeguards
2020-06-01
1
Inactivation of Arid1a in the endometrium is associated with endometrioid tumorigenesis through transcriptional reprogramming
2020-06-01
1
Integrated omics in Drosophila uncover a circadian kinome
2020-06-01
0.08
Integrating whole-genome sequencing within the National Antimicrobial Resistance Surveillance Program in the Philippines
2020-06-01
0.04
Machine learning uncovers cell identity regulator by histone code
2020-06-01
1
Massively parallel reporter assays of melanoma risk variants identify MX2 as a gene promoting melanoma
2020-06-01
0.63
Suppression of unwanted CRISPR-Cas9 editing by co-administration of catalytically inactivating truncated guide RNAs
2020-06-01
0.96
The MAO inhibitors phenelzine and clorgyline revert enzalutamide resistance in castration resistant prostate cancer
2020-06-01
0.62
The central amygdala recruits mesocorticolimbic circuitry for pursuit of reward or pain
2020-06-01
1
Triggering typical nemaline myopathy with compound heterozygous nebulin mutations reveals myofilament structural changes as pathomechanism
2020-06-01
1
A network of RNA-binding proteins controls translation efficiency to activate anaerobic metabolism
2020-05-29
0.86
Anisotropic ESCRT-III architecture governs helical membrane tube formation
2020-05-29
0.43
Detection of air and surface contamination by SARS-CoV-2 in hospital rooms of infected patients
2020-05-29
0.03
Evolution and structure of clinically relevant gene fusions in multiple myeloma
2020-05-29
1
TRPV4 disrupts mitochondrial transport and causes axonal degeneration via a CaMKII-dependent elevation of intracellular Ca2+
2020-05-29
1
The impact of agency on time and risk preferences
2020-05-29
1
Weaker neural suppression in autism
2020-05-29
1
Characterising the loss-of-function impact of 5’ untranslated region variants in 15,708 individuals
2020-05-27
0.55
Hippocampal seed connectome-based modeling predicts the feeling of stress
2020-05-27
1
Landscape of multi-nucleotide variants in 125,748 human exomes and 15,708 genomes
2020-05-27
0.59
Permissive microbiome characterizes human subjects with a neurovascular disease cavernous angioma
2020-05-27
1
Pregnancy reprograms the epigenome of mammary epithelial cells and blocks the development of premalignant lesions
2020-05-27
1
Vulnerabilities in coronavirus glycan shields despite extensive glycosylation
2020-05-27
0.36
CX-5461 activates the DNA damage response and demonstrates therapeutic efficacy in high-grade serous ovarian cancer
2020-05-26
0.04
Enabling safe aqueous lithium ion open batteries by suppressing oxygen reduction reaction
2020-05-26
1
Global priorities for conservation of reptilian phylogenetic diversity in the face of human impacts
2020-05-26
0.10
Partial cross mapping eliminates indirect causal influences
2020-05-26
0.14
Participatory practices at work change attitudes and behavior toward societal authority and justice
2020-05-26
1
Single cell transcriptomics reveals opioid usage evokes widespread suppression of antiviral gene program
2020-05-26
0.88
Sources of path integration error in young and aging humans
2020-05-26
0.53
Spread of pathological tau proteins through communicating neurons in human Alzheimer's disease
2020-05-26
0.75
Structural basis for effector protein recognition by the Dot/Icm Type IVB coupling protein complex
2020-05-26
0.13
The Perlman syndrome DIS3L2 exoribonuclease safeguards endoplasmic reticulum-targeted mRNA translation and calcium ion homeostasis
2020-05-26
1
The bromodomain containing protein BRD-9 orchestrates RAD51–RAD54 complex formation and regulates homologous recombination-mediated repair
2020-05-26
0.69
Nucleoporin 153 links nuclear pore complex to chromatin architecture by mediating CTCF and cohesin binding
2020-05-25
1
TGF-β signaling in Th17 cells promotes IL-22 production and colitis-associated colon cancer
2020-05-25
0.21
Ultrasensitive digital quantification of cytokines and bacteria predicts septic shock outcomes
2020-05-25
1
A biochemically-interpretable machine learning classifier for microbial GWAS
2020-05-22
0.80
A quantitative sequencing framework for absolute abundance measurements of mucosal and lumenal microbial communities
2020-05-22
1
A unified neurocognitive model of semantics language social behaviour and face recognition in semantic dementia
2020-05-22
0.05
An integrated multi-omics approach identifies the landscape of interferon-α-mediated responses of human pancreatic beta cells
2020-05-22
0.15
Dietary serine-microbiota interaction enhances chemotherapeutic toxicity without altering drug conversion
2020-05-22
1
Gestational alcohol exposure disrupts cognitive function and striatal circuits in adult offspring
2020-05-22
1
Sexual signaling pattern correlates with habitat pattern in visually ornamented fishes
2020-05-22
0.67
Single-cell analysis of murine fibroblasts identifies neonatal to adult switching that regulates cardiomyocyte maturation
2020-05-22
0.09
TNFAIP8 controls murine intestinal stem cell homeostasis and regeneration by regulating microbiome-induced Akt signaling
2020-05-22
0.89
Truncation of mutant huntingtin in knock-in mice demonstrates exon1 huntingtin is a key pathogenic form
2020-05-22
0.29
Using publicly available satellite imagery and deep learning to understand economic well-being in Africa
2020-05-22
1
Vesicular transport mediates the uptake of cytoplasmic proteins into mitochondria in Drosophila melanogastera
2020-05-22
0.09
A randomized trial evaluating virus-specific effects of a combination probiotic in children with acute gastroenteritis
2020-05-21
0.07
Epithelial plasticity can generate multi-lineage phenotypes in human and murine bladder cancers
2020-05-21
1
FoxO1–Dio2 signaling axis governs cardiomyocyte thyroid hormone metabolism and hypertrophic growth
2020-05-21
0.96
Glycopeptide epitope facilitates HIV-1 envelope specific humoral immune responses by eliciting T cell help
2020-05-21
1
Inferring multimodal latent topics from electronic health records
2020-05-21
0.42
Long-term alterations in brain and behavior after postnatal Zika virus infection in infant macaques
2020-05-21
1
Microbiome disturbance and resilience dynamics of the upper respiratory tract during influenza A virus infection
2020-05-21
0.75
Mitochondrial phosphatase PGAM5 modulates cellular senescence by regulating mitochondrial dynamics
2020-05-21
1
Multi-ancestry GWAS of the electrocardiographic PR interval identifies 202 loci underlying cardiac conduction
2020-05-21
0.34
Peripheral nerve resident macrophages share tissue-specific programming and features of activated microglia
2020-05-21
1
Construction of a web-based nanomaterial database by big data curation and modeling friendly nanostructure annotations
2020-05-20
0.67
Immunogenicity of a DNA vaccine candidate for COVID-19
2020-05-20
0.83
Loss of heterozygosity of essential genes represents a widespread class of potential cancer vulnerabilities
2020-05-20
1
DALRD3 encodes a protein mutated in epileptic encephalopathy that targets arginine tRNAs for 3-methylcytosine modification
2020-05-19
0.40
Dissecting the cellular specificity of smoking effects and reconstructing lineages in the human airway epithelium
2020-05-19
1
Fossils from Mille-Logya, Afar, Ethiopia, elucidate the link between Pliocene environmental changes and Homo origins
2020-05-19
0.58
Non-Markovian recovery makes complex networks more resilient against large-scale failures
2020-05-19
0.14
Precise phylogenetic analysis of microbial isolates and genomes from metagenomes using PhyloPhlAn 3.0
2020-05-19
0.39
Representation of visual uncertainty through neural gain variability
2020-05-19
0.80
Social-media and newspaper reports reveal large-scale meteorological drivers of floods on Sumatra
2020-05-19
0.30
Somatic SF3B1 hotspot mutation in prolactinomas
2020-05-19
0.13
Translational control of breast cancer plasticity
2020-05-19
0.08
A Cas9 with PAM recognition for adenine dinucleotides
2020-05-18
1
Adaptation of the master antioxidant response connects metabolism, lifespan and feather development pathways in birds
2020-05-18
1
Cas9-AAV6-engineered human mesenchymal stromal cells improved cutaneous wound healing in diabetic mice
2020-05-18
1
Determinants of transcription factor regulatory range
2020-05-18
0.64
Ecological drivers of global gradients in avian dispersal inferred from wing morphology
2020-05-18
0.06
Freeze-frame imaging of synaptic activity using SynTagMA
2020-05-18
0.40
Functionally distinct high and low theta oscillations in the human hippocampus
2020-05-18
1
Genetic and epigenetic intratumor heterogeneity impacts prognosis of lung adenocarcinoma
2020-05-18
0.80
HDAC1 modulates OGG1-initiated oxidative DNA damage repair in the aging brain and Alzheimer’s disease
2020-05-18
1
Histone H2A variants alpha1-extension helix directs RNF168-mediated ubiquitination
2020-05-18
0.75
Large-scale electron microscopy database for human type 1 diabetes
2020-05-18
0.38
Sphingolipids produced by gut bacteria enter host metabolic pathways impacting ceramide levels
2020-05-18
0.56
Structural insights into the inhibition mechanism of human sterol O-acyltransferase 1 by a competitive inhibitor
2020-05-18
0.30
TFEB regulates murine liver cell fate during development and regeneration
2020-05-18
0.66
A redox-based electrogenetic CRISPR system to connect with and control biological information networks
2020-05-15
1
A role for actin flexibility in thin filament-mediated contractile regulation and myopathy
2020-05-15
0.80
Antigenic assessment of the H3N2 component of the 2019-2020 Northern Hemisphere influenza vaccine
2020-05-15
1
Ballistic supercavitating nanoparticles driven by single Gaussian beam optical pushing and pulling forces
2020-05-15
1
Conserved protein Pir2ARS2 mediates gene repression through cryptic introns in lncRNAs
2020-05-15
1
DNA polymerase ε relies on a unique domain for efficient replisome assembly and strand synthesis
2020-05-15
1
Dynamic reconfiguration of functional brain networks during working memory training
2020-05-15
0.43
Germline variant burden in cancer genes correlates with age at diagnosis and somatic mutation burden
2020-05-15
0.95
HIV-associated gut dysbiosis is independent of sexual practice and correlates with noncommunicable diseases
2020-05-15
0.56
Immune-profiling of ZIKV-infected patients identifies a distinct function of plasmacytoid dendritic cells for immune cross-regulation
2020-05-15
1
Investigating the dynamics of microbial consortia in spatially structured environments
2020-05-15
1
Mutations in the KIF21B kinesin gene cause neurodevelopmental disorders through imbalanced canonical motor activity
2020-05-15
0.32
Oncogenic hijacking of a developmental transcription factor evokes vulnerability toward oxidative stress in Ewing sarcoma
2020-05-15
0.08
Representation of probabilistic outcomes during risky decision-making
2020-05-15
0.02
Ribonucleotide incorporation in yeast genomic DNA shows preference for cytosine and guanosine preceded by deoxyadenosine
2020-05-15
1
Synergistic lipid compositions for albumin receptor mediated delivery of mRNA to the liver
2020-05-15
0.90
Synergy between the anthocyanin and RDR6/SGS3/DCL4 siRNA pathways expose hidden features of Arabidopsis carbon metabolism
2020-05-15
1
Targeting lysyl oxidase (LOX) overcomes chemotherapy resistance in triple negative breast cancer
2020-05-15
0.24
The native ORAI channel trio underlies the diversity of Ca2+ signaling events
2020-05-15
0.92
Trajectory-modulated hippocampal neurons persist throughout memory-guided navigation
2020-05-15
1
Unique properties of a subset of human pluripotent stem cells with high capacity for self-renewal
2020-05-15
0.15
mRNA display with library of even-distribution reveals cellular interactors of influenza virus NS1
2020-05-15
0.82
Ecology and allometry predict the evolution of avian developmental durations
2020-05-14
0.05
Genotoxic stress triggers the activation of IRE1α-dependent RNA decay to modulate the DNA damage response
2020-05-14
0.09
Mitochondrial uncoupler BAM15 reverses diet-induced obesity and insulin resistance in mice
2020-05-14
0.22
Plasma membrane H+-ATPases sustain pollen tube growth and fertilization
2020-05-14
0.27
Resistance to targeted therapies as a multifactorial, gradual adaptation to inhibitor specific selective pressures
2020-05-14
0.92
Scale and information-processing thresholds in Holocene social evolution
2020-05-14
0.96
BAF60a deficiency uncouples chromatin accessibility and cold sensitivity from white fat browning
2020-05-13
0.91
Characterization of the development of the mouse cochlear epithelium at the single cell level
2020-05-13
0.93
Chemotaxing neutrophils enter alternate branches at capillary bifurcations
2020-05-13
0.40
Deep brain stimulation-guided optogenetic rescue of parkinsonian symptoms
2020-05-13
0.19
Target-responsive vasoactive probes for ultrasensitive molecular imaging
2020-05-13
1
YAP1/TAZ drives ependymoma-like tumour formation in mice
2020-05-13
0.07
Dissociable neural correlates of uncertainty underlie different exploration strategies
2020-05-12
1
Hepatocyte mitochondria-derived danger signals directly activate hepatic stellate cells and drive progression of liver fibrosis
2020-05-12
0.81
Integration of multiple biological contexts reveals principles of synthetic lethality that affect reproducibility
2020-05-12
1
Legionella effector MavC targets the Ube2N~Ub conjugate for noncanonical ubiquitination
2020-05-12
1
MBNL1 regulates essential alternative RNA splicing patterns in MLL-rearranged leukemia
2020-05-12
1
Massive peatland carbon banks vulnerable to rising temperatures
2020-05-12
1
Microplastics affect sedimentary microbial communities and nitrogen cycling
2020-05-12
1
N-AS-triggered SPMs are direct regulators of microglia in a model of Alzheimer’s disease
2020-05-12
0.08
Naked mole-rat very-high-molecular-mass hyaluronan exhibits superior cytoprotective properties
2020-05-12
0.86
PTSD is associated with neuroimmune suppression: evidence from PET imaging and postmortem transcriptomic studies
2020-05-12
1
A deubiquitylase with an unusually high-affinity ubiquitin-binding domain from the scrub typhus pathogen Orientia tsutsugamushi
2020-05-11
1
Acquired resistance to combined BET and CDK4/6 inhibition in triple-negative breast cancer
2020-05-11
1
Computational stabilization of T cell receptors allows pairing with antibodies to form bispecifics
2020-05-11
1
Deep learning enables accurate clustering with batch effect removal in single-cell RNA-seq analysis
2020-05-11
0.73
Multi-omic single-cell snapshots reveal multiple independent trajectories to drug tolerance in a melanoma cell line
2020-05-11
0.94
Multiplex precise base editing in cynomolgus monkeys
2020-05-11
0.32
ORF Capture-Seq as a versatile method for targeted identification of full-length isoforms
2020-05-11
0.76
Protein-altering germline mutations implicate novel genes related to lung cancer development
2020-05-11
0.40
Synergistic effect of fasting-mimicking diet and vitamin C against KRAS mutated cancers
2020-05-11
0.33
A RUNX2 stabilization pathway mediates physiologic and pathologic bone formation
2020-05-08
0.58
A phenome-wide association and Mendelian Randomisation study of polygenic risk for depression in UK Biobank
2020-05-08
0.18
ABCG2 transports anticancer drugs via a closed-to-open switch
2020-05-08
1
Abstract representations of events arise from mental errors in learning and memory
2020-05-08
1
Bioorthogonal non-canonical amino acid tagging reveals translationally active subpopulations of the cystic fibrosis lung microbiota
2020-05-08
1
Distinct fate, dynamics and niches of renal macrophages of bone marrow or embryonic origins
2020-05-08
1
Effect of sequence depth and length in long-read assembly of the maize inbred NC358
2020-05-08
1
Epigenome environment interactions accelerate epigenomic aging and unlock metabolically restricted epigenetic reprogramming in adulthood
2020-05-08
1
Evolution of cooperation on temporal networks
2020-05-08
0.56
Imaging radiation dose in breast radiotherapy by X-ray CT calibration of Cherenkov light
2020-05-08
1
Light-triggered release of conventional local anesthetics from a macromolecular prodrug for on-demand local anesthesia
2020-05-08
1
Mechanoradicals in tensed tendon collagen as a source of oxidative stress
2020-05-08
0.07
Negative elongation factor complex enables macrophage inflammatory responses by controlling anti-inflammatory gene expression
2020-05-08
0.36
Plasma membrane damage causes NLRP3 activation and pyroptosis during Mycobacterium tuberculosis infection
2020-05-08
0.08
Predicting the global mammalian viral sharing network using phylogeography
2020-05-08
0.92
Structural basis for impairment of DNA methylation by the DNMT3A R882H mutation
2020-05-08
1
Structural basis of transmembrane coupling of the HIV-1 envelope glycoprotein
2020-05-08
1
Systematically optimized BCMA/CS1 bispecific CAR-T cells robustly control heterogeneous multiple myeloma
2020-05-08
1
The scaffold protein p62 regulates adaptive thermogenesis through ATF2 nuclear target activation
2020-05-08
0.19
Variation among 532 genomes unveils the origin and evolutionary history of a global insect herbivore
2020-05-08
0.01
p85β regulates autophagic degradation of AXL to activate oncogenic signaling
2020-05-08
0.23
A method for the generation of human stem cell-derived alpha cells
2020-05-07
0.67
Analysis of cardiac magnetic resonance imaging in 36,000 individuals yields genetic insights into dilated cardiomyopathy
2020-05-07
1
Evolutionary conserved NSL complex/BRD4 axis controls transcription activation via histone acetylation
2020-05-07
0.09
Mapping global carbon footprint in China
2020-05-07
0.32
Reaction mechanism and kinetics for CO2 reduction on nickel single atom catalysts from quantum mechanics
2020-05-07
0.65
Structural basis for Ca2+-dependent activation of a plant metacaspase
2020-05-07
1
Disruption of ATRX-RNA interactions uncovers roles in ATRX localization and PRC2 function
2020-05-06
1
High residual carriage of vaccine-serotype Streptococcus pneumoniae after introduction of pneumococcal conjugate vaccine in Malawi
2020-05-06
0.03
Comprehensive germline genomic profiles of children, adolescents and young adults with solid tumors
2020-05-05
1
Demographic and genetic factors influence the abundance of infiltrating immune cells in human tissues
2020-05-05
1
Magnetically driven active topography for long-term biofilm control
2020-05-05
1
Mutualist and pathogen traits interact to affect plant community structure in a spatially explicit model
2020-05-05
0.40
N-GSDMD trafficking to neutrophil organelles facilitates IL-1β release independently of plasma membrane pores and pyroptosis
2020-05-05
0.85
Segregation of an MSH1 RNAi transgene produces heritable non-genetic memory in association with methylome reprogramming
2020-05-05
1
Comprehensive aptamer-based screening identifies a spectrum of urinary biomarkers of lupus nephritis across ethnicities
2020-05-04
0.83
Diversity in medullary thymic epithelial cells controls the activity and availability of iNKT cells
2020-05-04
0.10
Encoding quantized fluorescence states with fractal DNA frameworks
2020-05-04
0.12
Exercise enhances motor skill learning by neurotransmitter switching in the adult midbrain
2020-05-04
1
Nucleoplasmic signals promote directed transmembrane protein import simultaneously via multiple channels of nuclear pores
2020-05-04
0.80
TALPID3 and ANKRD26 selectively orchestrate FBF1 localization and cilia gating
2020-05-04
0.50
TRAF3IP3 negatively regulates cytosolic RNA induced anti-viral signaling by promoting TBK1 K48 ubiquitination
2020-05-04
0.94
Turbulent coherent structures and early life below the Kolmogorov scale
2020-05-04
1
A divisive model of evidence accumulation explains uneven weighting of evidence over time
2020-05-01
1
Alternative splicing controls teneurin-latrophilin interaction and synapse specificity by a shape-shifting mechanism
2020-05-01
1
Critical slowing down as a biomarker for seizure susceptibility
2020-05-01
0.04
DIP/Dpr interactions and the evolutionary design of specificity in protein families
2020-05-01
1
Effective combinatorial immunotherapy for penile squamous cell carcinoma
2020-05-01
0.92
Endothelin-1 signaling maintains glial progenitor proliferation in the postnatal subventricular zone
2020-05-01
0.61
Estrogen receptor-α expressing neurons in the ventrolateral VMH regulate glucose balance
2020-05-01
1
Fire deficit increases wildfire risk for many communities in the Canadian boreal forest
2020-05-01
0.13
Global CO emissions from dry inland waters share common drivers across ecosystems
2020-05-01
0.02
Increased mitochondrial calcium levels associated with neuronal death in a mouse model of Alzheimer’s disease
2020-05-01
0.92
Long non-coding RNA RAMS11 promotes metastatic colorectal cancer progression
2020-05-01
1
Midkine activation of CD8+ T cells establishes a neuron–immune–cancer axis responsible for low-grade glioma growth
2020-05-01
1
Mutualism increases diversity, stability, and function of multiplex networks that integrate pollinators into food webs
2020-05-01
1
PBRM1 loss defines a nonimmunogenic tumor phenotype associated with checkpoint inhibitor resistance in renal carcinoma
2020-05-01
0.97
Photoactivatable Cre recombinase 3.0 for in vivo mouse applications
2020-05-01
0.91
Recent hybrids recapitulate ancient hybrid outcomes
2020-05-01
1
Stability and nuclear localization of yeast telomerase depend on protein components of RNase P/MRP
2020-05-01
1
The Set1 N-terminal domain and Swd2 interact with RNA polymerase II CTD to recruit COMPASS
2020-05-01
0.44
Ubiquitinated-PCNA protects replication forks from DNA2-mediated degradation by regulating Okazaki fragment maturation and chromatin assembly
2020-05-01
1
Ultrastructural visualization of 3D chromatin folding using volume electron microscopy and DNA in situ hybridization
2020-05-01
0.16
A drug-inducible sex-separation technique for insects
2020-04-30
1
Dysregulation of bile acids increases the risk for preterm birth in pregnant women
2020-04-30
0.83
Endemism patterns are scale dependent
2020-04-30
0.25
Highly parallel and efficient single cell mRNA sequencing with paired picoliter chambers
2020-04-30
0.14
Model-driven generation of artificial yeast promoters
2020-04-30
1
Positron emission tomography imaging of novel AAV capsids maps rapid brain accumulation
2020-04-30
1
Single-cell transcriptional networks in differentiating preadipocytes suggest drivers associated with tissue heterogeneity
2020-04-30
0.89
The cooperative action of CSB, CSA, and UVSSA target TFIIH to DNA damage-stalled RNA polymerase II
2020-04-30
0.17
The impact of antimalarial resistance on the genetic structure of Plasmodium falciparum in the DRC
2020-04-30
0.59
Timed inhibition of CDC7 increases CRISPR-Cas9 mediated templated repair
2020-04-30
0.91
A live cell reporter of exosome secretion and uptake reveals pathfinding behavior of migrating cells
2020-04-29
1
Astrovirus infects actively secreting goblet cells and alters the gut mucus barrier
2020-04-29
1
Haplotype-resolved genomes provide insights into structural variation and gene content in Angus and Brahman cattle
2020-04-29
0.68
Improved GPCR ligands from nanobody tethering
2020-04-29
1
Inferring spatial and signaling relationships between cells from single cell transcriptomic data
2020-04-29
1
Intron retention is a hallmark and spliceosome represents a therapeutic vulnerability in aggressive prostate cancer
2020-04-29
0.87
LSD1-mediated enhancer silencing attenuates retinoic acid signalling during pancreatic endocrine cell development
2020-04-29
1
Local conditions and policy design determine whether ecological compensation can achieve No Net Loss goals
2020-04-29
0.37
Motivated misremembering of selfish decisions
2020-04-29
0.40
Myosin-VIIa is expressed in multiple isoforms and essential for tensioning the hair cell mechanotransduction complex
2020-04-29
1
Structural basis for DNA damage-induced phosphoregulation of MDM2 RING domain
2020-04-29
0.25
Synthetic hybrids of six yeast species
2020-04-29
0.98
Task-induced attention load guides and gates unconscious semantic interference
2020-04-29
1
A HaloTag-TEV genetic cassette for mechanical phenotyping of proteins from tissues
2020-04-28
0.21
Artifact-free and high-temporal-resolution in vivo opto-electrophysiology with microLED optoelectrodes
2020-04-28
0.92
Cytosine base editors with minimized unguided DNA and RNA off-target events and high on-target activity
2020-04-28
1
Extracellular electron transfer-dependent anaerobic oxidation of ammonium by anammox bacteria
2020-04-28
0.11
LipidCreator workbench to probe the lipidomic landscape
2020-04-28
0.10
Prefrontal reinstatement of contextual task demand is predicted by separable hippocampal patterns
2020-04-28
1
Promoter-anchored chromatin interactions predicted from genetic analysis of epigenomic data
2020-04-28
0.09
Proteogenomics analysis unveils a TFG-RET gene fusion and druggable targets in papillary thyroid carcinomas
2020-04-28
0.21
The BRCA2-MEILB2-BRME1 complex governs meiotic recombination and impairs the mitotic BRCA2-RAD51 function in cancer cells
2020-04-28
0.33
Aging-regulated anti-apoptotic long non-coding RNA Sarrah augments recovery from acute myocardial infarction
2020-04-27
0.06
Endothelial E-selectin inhibition improves acute myeloid leukaemia therapy by disrupting vascular niche-mediated chemoresistance
2020-04-27
0.11
Neutrophil swarming delays the growth of clusters of pathogenic fungi
2020-04-27
1
Repurposing a chemosensory macromolecular machine
2020-04-27
0.64
Targeted delivery of nanomaterials with chemical cargoes in plants enabled by a biorecognition motif
2020-04-27
1
The phylogenetic landscape and nosocomial spread of the multidrug-resistant opportunist Stenotrophomonas maltophilia
2020-04-27
0.03
A masked initiation region in retinoblastoma protein regulates its proteasomal degradation
2020-04-24
1
A mycorrhizae-like gene regulates stem cell and gametophore development in mosses
2020-04-24
0.13
Accurate estimation of cell composition in bulk expression through robust integration of single-cell information
2020-04-24
0.90
Apolipoprotein J is a hepatokine regulating muscle glucose metabolism and insulin sensitivity
2020-04-24
0.68
Chemical modifications of adenine base editor mRNA and guide RNA expand its application scope
2020-04-24
0.94
Conditional deletion of Nedd4-2 in lung epithelial cells causes progressive pulmonary fibrosis in adult mice
2020-04-24
0.09
Confidence reports in decision-making with multiple alternatives violate the Bayesian confidence hypothesis
2020-04-24
1
Endogenous and exogenous control of visuospatial selective attention in freely behaving mice
2020-04-24
1
Escape mutations circumvent a tradeoff between resistance to a beta-lactam and resistance to a beta-lactamase inhibitor
2020-04-24
0.22
Fatal heart disease among cancer patients
2020-04-24
1
Glial type specific regulation of CNS angiogenesis by HIFα-activated different signaling pathways
2020-04-24
1
HyperTRIBE uncovers increased MUSASHI-2 RNA binding activity and differential regulation in leukemic stem cells
2020-04-24
0.94
Integrative multiplatform molecular profiling of benign prostatic hyperplasia identifies distinct subtypes
2020-04-24
0.89
Loss of MBNL1 induces RNA misprocessing in the thymus and peripheral blood
2020-04-24
1
Mapping the spreading routes of lymphatic metastases in human colorectal cancer
2020-04-24
0.08
Methylation of Salmonella Typhimurium flagella promotes bacterial adhesion and host cell invasion
2020-04-24
0.11
Modeling biological and genetic diversity in upper tract urothelial carcinoma with patient derived xenografts
2020-04-24
0.95
Non-coding somatic mutations converge on the PAX8 pathway in ovarian cancer
2020-04-24
0.88
Stress gates an astrocytic energy reservoir to impair synaptic plasticity
2020-04-24
0.38
The UPR sensor IRE1α and the adenovirus E3-19K glycoprotein sustain persistent and lytic infections
2020-04-24
0.13
The vaginal microbiota associates with the regression of untreated cervical intraepithelial neoplasia 2 lesions
2020-04-24
0.11
Topography and human pressure in mountain ranges alter expected species responses to climate change
2020-04-24
1
Transcription-coupled repair and mismatch repair contribute towards preserving genome integrity at mononucleotide repeat tracts
2020-04-24
0.08
Uncoupling of invasive bacterial mucosal immunogenicity from pathogenicity
2020-04-24
0.06
Using proteolysis-targeting chimera technology to reduce navitoclax platelet toxicity and improve its senolytic activity
2020-04-24
1
Aspartate aminotransferase Rv3722c governs aspartate-dependent nitrogen metabolism in Mycobacterium tuberculosis
2020-04-23
1
Cryo-EM structure of the PlexinC1/A39R complex reveals inter-domain interactions critical for ligand-induced activation
2020-04-23
1
Deletion of Topoisomerase 1 in excitatory neurons causes genomic instability and early onset neurodegeneration
2020-04-23
1
Dynamic states of population activity in prefrontal cortical networks of freely-moving macaque
2020-04-23
1
Functional and molecular heterogeneity of D2R neurons along dorsal ventral axis in the striatum
2020-04-23
0.19
Noninvasive electromagnetic source imaging of spatiotemporally distributed epileptogenic brain sources
2020-04-23
1
Novel metabolic role for BDNF in pancreatic β-cell insulin secretion
2020-04-23
1
Propagation of hippocampal ripples to the neocortex by way of a subiculum-retrosplenial pathway
2020-04-23
0.38
Sex chromosome evolution in parasitic nematodes of humans
2020-04-23
0.78
Single-cell bacterial transcription measurements reveal the importance of dimethylsulfoniopropionate (DMSP) hotspots in ocean sulfur cycling
2020-04-23
0.15
Consistent RNA sequencing contamination in GTEx and other data sets
2020-04-22
1
Context information supports serial dependence of multiple visual objects across memory episodes
2020-04-22
0.08
Deep learning enables structured illumination microscopy with low light levels and enhanced speed
2020-04-22
0.74
Development of a thermophilic coculture for corn fiber conversion to ethanol
2020-04-22
1
Lgr5+ telocytes are a signaling source at the intestinal villus tip
2020-04-22
0.24
Proteasome inhibitor-induced modulation reveals the spliceosome as a specific therapeutic vulnerability in multiple myeloma
2020-04-22
1
A Cdc42-mediated supracellular network drives polarized forces and Drosophila egg chamber extension
2020-04-21
0.27
A kinome-wide screen identifies a CDKL5-SOX9 regulatory axis in epithelial cell death and kidney injury
2020-04-21
0.87
Biological weed control to relieve millions from Ambrosia allergies in Europe
2020-04-21
0.04
Circadian regulation of mitochondrial uncoupling and lifespan
2020-04-21
1
Collagen-producing lung cell atlas identifies multiple subsets with distinct localization and relevance to fibrosis
2020-04-21
0.86
Exploiting evolutionary steering to induce collateral drug sensitivity in cancer
2020-04-21
0.05
Structural basis for active single and double ring complexes in human mitochondrial Hsp60-Hsp10 chaperonin
2020-04-21
0.23
Timing the initiation of multiple myeloma
2020-04-21
0.33
A double-hit of stress and low-grade inflammation on functional brain network mediates posttraumatic stress symptoms
2020-04-20
0.05
A fully orthogonal system for protein synthesis in bacterial cells
2020-04-20
1
Connecting concepts in the brain by mapping cortical representations of semantic relations
2020-04-20
1
High throughput pMHC-I tetramer library production using chaperone-mediated peptide exchange
2020-04-20
1
Mouse tracking reveals structure knowledge in the absence of model-based choice
2020-04-20
0.67
Multiplex secretome engineering enhances recombinant protein production and purity
2020-04-20
0.28
Optogenetic manipulation of a value-coding pathway from the primate caudate tail facilitates saccadic gaze shift
2020-04-20
0.30
Quantitative cellular-resolution map of the oxytocin receptor in postnatally developing mouse brains
2020-04-20
0.80
Scavenger receptor-A is a biomarker and effector of rheumatoid arthritis: A large-scale multicenter study
2020-04-20
0.06
Self-sustainable protonic ceramic electrochemical cells using a triple conducting electrode for hydrogen and power production
2020-04-20
1
Stochasticity constrained by deterministic effects of diet and age drive rumen microbiome assembly dynamics
2020-04-20
0.30
Super-resolution imaging reveals the evolution of higher-order chromatin folding in early carcinogenesis
2020-04-20
0.93
Switched-capacitor-convertors based on fractal design for output power management of triboelectric nanogenerator
2020-04-20
0.07
Synthesis and evaluation of designed PKC modulators for enhanced cancer immunotherapy
2020-04-20
1
TAGAP instructs Th17 differentiation by bridging Dectin activation to EPHB2 signaling in innate antifungal response
2020-04-20
0.12
TRIM21 and PHLDA3 negatively regulate the crosstalk between the PI3K/AKT pathway and PPP metabolism
2020-04-20
0.18
The chloroalkaloid (−)-acutumine is biosynthesized via a Fe(II)- and 2-oxoglutarate-dependent halogenase in Menispermaceae plants
2020-04-20
1
The endoplasmic reticulum stress-autophagy pathway controls hypothalamic development and energy balance regulation in leptin-deficient neonates
2020-04-20
0.58
α-Synuclein-specific T cell reactivity is associated with preclinical and early Parkinson’s disease
2020-04-20
0.94
A delay in sampling information from temporally autocorrelated visual stimuli
2020-04-15
0.67
A gravity-based three-dimensional compass in the mouse brain
2020-04-15
0.86
A processive phosphorylation circuit with multiple kinase inputs and mutually diversional routes controls G1/S decision
2020-04-15
0.11
A rationally enhanced red fluorescent protein expands the utility of FRET biosensors
2020-04-15
1
Genome-wide analysis highlights contribution of immune system pathways to the genetic architecture of asthma
2020-04-15
1
Increased burden of ultra-rare structural variants localizing to boundaries of topologically associated domains in schizophrenia
2020-04-15
0.47
Regulation of reactive oxygen species during plant immunity through phosphorylation and ubiquitination of RBOHD
2020-04-15
1
Spatially resolved analyses link genomic and immune diversity and reveal unfavorable neutrophil activation in melanoma
2020-04-15
0.98
XPO5 promotes primary miRNA processing independently of RanGTP
2020-04-15
1
Adrenergic stress constrains the development of anti-tumor immunity and abscopal responses following local radiation
2020-04-14
1
Capturing the primordial Kras mutation initiating urethane carcinogenesis
2020-04-14
1
Cellular origins and genetic landscape of cutaneous gamma delta T cell lymphomas
2020-04-14
1
Chronic activation of hexosamine biosynthesis in the heart triggers pathological cardiac remodeling
2020-04-14
0.95
Computational analysis of pathological images enables a better diagnosis of TFE3 Xp11.2 translocation renal cell carcinoma
2020-04-14
0.70
Dietary lipids fuel GPX4-restricted enteritis resembling Crohn’s disease
2020-04-14
0.03
Elevated protein synthesis in microglia causes autism-like synaptic and behavioral aberrations
2020-04-14
0.63
Glycolytic reprograming in Salmonella counters NOX2-mediated dissipation of ΔpH
2020-04-14
1
Minimum epistasis interpolation for sequence-function relationships
2020-04-14
1
Modulation of virus-induced NF-κB signaling by NEMO coiled coil mimics
2020-04-14
0.95
Natural killer cells modulate motor neuron-immune cell cross talk in models of Amyotrophic Lateral Sclerosis
2020-04-14
0.08
P2X7 receptor inhibition ameliorates dendritic spine pathology and social behavioral deficits in Rett syndrome mice
2020-04-14
1
Pan-active imidazolopiperazine antimalarials target the Plasmodium falciparum intracellular secretory pathway
2020-04-14
0.79
Potent BRD4 inhibitor suppresses cancer cell-macrophage interaction
2020-04-14
0.31
Quantifying the heterogeneity of macromolecular machines by mass photometry
2020-04-14
0.35
RNA-DNA strand exchange by the Drosophila Polycomb complex PRC2
2020-04-14
0.44
SciBet as a portable and fast single cell type identifier
2020-04-14
0.13
Selective inhibition of cancer cell self-renewal through a Quisinostat-histone H1.0 axis
2020-04-14
0.06
Sex-associated molecular differences for cancer immunotherapy
2020-04-14
0.76
Sex-specific innate immune selection of HIV-1 in utero is associated with increased female susceptibility to infection
2020-04-14
0.08
Single-cell transcriptomics identifies an effectorness gradient shaping the response of CD4 T cells to cytokines
2020-04-14
0.07
Structural dynamics in proteins induced by and probed with X-ray free-electron laser pulses
2020-04-14
0.27
Structural insights into the mechanism and inhibition of transglutaminase-induced ubiquitination by the Legionella effector MavC
2020-04-14
0.15
The Sox2 transcription factor binds RNA
2020-04-14
1
Transposable elements contribute to cell and species-specific chromatin looping and gene regulation in mammalian genomes
2020-04-14
1
An intracellular membrane protein GEP1 regulates xanthurenic acid induced gametogenesis of malaria parasites
2020-04-09
0.07
Bionic 3D printed corals
2020-04-09
0.49
Cancer neoantigen prioritization through sensitive and reliable proteogenomics analysis
2020-04-09
1
Identity and function of an essential nitrogen ligand of the nitrogenase cofactor biosynthesis protein NifB
2020-04-09
1
Prostate-specific antigen dynamics predict individual responses to intermittent androgen deprivation
2020-04-09
1
TGFβ suppresses CD8+ T cell expression of CXCR3 and tumor trafficking
2020-04-09
1
Cholinergic midbrain afferents modulate striatal circuits and shape encoding of action strategies
2020-04-08
0.57
DNA punch cards for storing data on native DNA sequences via enzymatic nicking
2020-04-08
1
A simple contagion process describes spreading of traffic jams in urban networks
2020-04-07
0.18
Gating mechanism of elongating β-ketoacyl-ACP synthases
2020-04-07
1
Quantitative proteomic landscape of metaplastic breast carcinoma pathological subtypes and their relationship to triple-negative tumors
2020-04-07
1
TrkB-expressing paraventricular hypothalamic neurons suppress appetite through multiple neurocircuits
2020-04-07
0.83
Wireless optogenetics protects against obesity via stimulation of non-canonical fat thermogenesis
2020-04-07
1
A behavioral approach to instability pathways in financial markets
2020-04-06
0.20
Dynamic genome evolution and complex virocell metabolism of globally-distributed giant viruses
2020-04-06
1
Faster Atlantic currents drive poleward expansion of temperate phytoplankton in the Arctic Ocean
2020-04-06
0.06
Organoid cultures from normal and cancer-prone human breast tissues preserve complex epithelial lineages
2020-04-06
0.86
Structural morphing in a symmetry-mismatched viral vertex
2020-04-06
1
Accelerated dryland expansion regulates future variability in dryland gross primary production
2020-04-03
0.56
Angiotensin II induces coordinated calcium bursts in aldosterone-producing adrenal rosettes
2020-04-03
1
Cerebrospinal fluid p-tau217 performs better than p-tau181 as a biomarker of Alzheimer’s disease
2020-04-03
0.53
Comprehensive sequence-to-function mapping of cofactor-dependent RNA catalysis in the glmS ribozyme
2020-04-03
1
Diagnosis and prognosis of myocardial infarction on a plasmonic chip
2020-04-03
0.09
Functional brain network reconfiguration during learning in a dynamic environment
2020-04-03
1
Increasing ambient temperature progressively disassembles Arabidopsis phytochrome B from individual photobodies with distinct thermostabilities
2020-04-03
1
Oncogenic Kras causes myeloproliferation via NLRP3 inflammasome activation
2020-04-03
0.04
Optogenetic restoration of retinal ganglion cell activity in the living primate
2020-04-03
1
Pyrazinamide triggers degradation of its target aspartate decarboxylase
2020-04-03
0.38
RXRs control serous macrophage neonatal expansion and identity and contribute to ovarian cancer progression
2020-04-03
0.36
Remodeling of active endothelial enhancers is associated with aberrant gene-regulatory networks in pulmonary arterial hypertension
2020-04-03
0.71
Spatial contextual effects in primary visual cortex limit feature representation under crowding
2020-04-03
1
Stem cell-derived polarized hepatocytes
2020-04-03
0.67
The circadian clock and darkness control natural competence in cyanobacteria
2020-04-03
1
Translational derepression of  isoforms at their alternative 5′ UTRs determines neuronal development
2020-04-03
0.75
β-Catenin and FGFR2 regulate postnatal rosette-based adrenocortical morphogenesis
2020-04-03
0.82
Analog content-addressable memories with memristors
2020-04-02
0.93
Dual functions of Aire CARD multimerization in the transcriptional regulation of T cell tolerance
2020-04-02
1
Essential dynamic interdependence of FtsZ and SepF for Z-ring and septum formation in Corynebacterium glutamicum
2020-04-02
0.07
GPR56/ADGRG1 is associated with response to antidepressant treatment
2020-04-02
0.04
Phasor field diffraction based reconstruction for fast non-line-of-sight imaging systems
2020-04-02
1
TNIK signaling imprints CD8 T cell memory formation early after priming
2020-04-02
0.09
Effective CRISPRa-mediated control of gene expression in bacteria must overcome strict target site requirements
2020-04-01
1
Endothelialization of arterial vascular grafts by circulating monocytes
2020-04-01
1
Loss of testosterone impairs anti-tumor neutrophil function
2020-03-31
1
Metagenome-wide association of gut microbiome features for schizophrenia
2020-03-31
0.03
The genetic architecture of membranous nephropathy and its potential to improve non-invasive diagnosis
2020-03-30
0.23
Activation and self-inactivation mechanisms of the cyclic oligoadenylate-dependent CRISPR ribonuclease Csm6
2020-03-27
0.22
Adar RNA editing-dependent and -independent effects are required for brain and innate immune functions in
2020-03-27
0.25
Differential regulation of breast cancer bone metastasis by PARP1 and PARP2
2020-03-27
1
Human iPSC-derived mature microglia retain their identity and functionally integrate in the chimeric mouse brain
2020-03-27
0.93
Integrative differential expression and gene set enrichment analysis using summary statistics for scRNA-seq studies
2020-03-27
0.83
Mapping the breast cancer metastatic cascade onto ctDNA using genetic and epigenetic clonal tracking
2020-03-27
0.17
Modulation of BIN2 kinase activity by HY5 controls hypocotyl elongation in the light
2020-03-27
0.10
Synthetic antibodies against BRIL as universal fiducial marks for single−particle cryoEM structure determination of membrane proteins
2020-03-27
0.98
Unveiling reductant chemistry in fabricating noble metal aerogels for superior oxygen evolution and ethanol oxidation
2020-03-27
0.11
Activity-dependent isomerization of Kv4.2 by Pin1 regulates cognitive flexibility
2020-03-26
1
Dimensionality reduction reveals fine-scale structure in the Japanese population with consequences for polygenic risk prediction
2020-03-26
0.07
Runx-mediated regulation of CCL5 via antagonizing two enhancers influences immune cell function and anti-tumor immunity
2020-03-26
0.14
The secreted protease Adamts18 links hormone action to activation of the mammary stem cell niche
2020-03-26
0.14
A common MET polymorphism harnesses HER2 signaling to drive aggressive squamous cell carcinoma
2020-03-25
0.01
Generating high quality libraries for DIA MS with empirically corrected peptide predictions
2020-03-25
0.43
Human activity recognition using magnetic induction-based motion signals and deep recurrent neural networks
2020-03-25
1
Mapping anthropogenic mineral generation in China and its implications for a circular economy
2020-03-25
0.21
Rigidity enhances a magic-number effect in polymer phase separation
2020-03-25
0.86
c-di-GMP modulates type IV MSHA pilus retraction and surface attachment in Vibrio cholerae
2020-03-25
0.95
A Staphylococcus pro-apoptotic peptide induces acute exacerbation of pulmonary fibrosis
2020-03-24
0.30
Different regions of synaptic vesicle membrane regulate VAMP2 conformation for the SNARE assembly
2020-03-24
0.19
Dimensionality reduction by UMAP to visualize physical and genetic interactions
2020-03-24
1
Genomic analysis of male puberty timing highlights shared genetic basis with hair colour and lifespan
2020-03-24
0.41
Identifying a human signal in the North Atlantic warming hole
2020-03-24
0.83
Maternal carriage of Prevotella during pregnancy associates with protection against food allergy in the offspring
2020-03-24
0.13
Subpopulation targeting of pyruvate dehydrogenase and GLUT1 decouples metabolic heterogeneity during collective cancer cell invasion
2020-03-24
1
Transient non-integrative expression of nuclear reprogramming factors promotes multifaceted amelioration of aging in human cells
2020-03-24
1
Ultrasensitive detection of nucleic acids using deformed graphene channel field effect biosensors
2020-03-24
0.96
8q24 genetic variation and comprehensive haplotypes altering familial risk of prostate cancer
2020-03-23
1
Colonic microbiota is associated with inflammation and host epigenomic alterations in inflammatory bowel disease
2020-03-23
0.15
Leptin receptor-expressing neuron Sh2b1 supports sympathetic nervous system and protects against obesity and metabolic disease
2020-03-23
1
An acid-tolerance response system protecting exponentially growing
2020-03-20
0.08
Dissecting the role of PfAP2-G in malaria gametocytogenesis
2020-03-20
1
Groundwater as a major source of dissolved organic matter to Arctic coastal waters
2020-03-20
1
Lipid analogs reveal features critical for hemolysis and diminish granadaene mediated Group B Streptococcus infection
2020-03-20
0.51
NELL2-Robo3 complex structure reveals mechanisms of receptor activation for axon guidance
2020-03-20
1
Reproductive tract extracellular vesicles are sufficient to transmit intergenerational stress and program neurodevelopment
2020-03-20
1
Shotgun ion mobility mass spectrometry sequencing of heparan sulfate saccharides
2020-03-20
0.21
The cryo-EM structure of the SNX–BAR Mvp1 tetramer
2020-03-20
0.88
The mechanism of a high-affinity allosteric inhibitor of the serotonin transporter
2020-03-20
0.22
Therapeutic modulation of phagocytosis in glioblastoma can activate both innate and adaptive antitumour immunity
2020-03-20
0.94
Comprehensive genomic analysis of dietary habits in UK Biobank identifies hundreds of genetic associations
2020-03-19
1
Excitatory VTA to DH projections provide a valence signal to memory circuits
2020-03-19
0.91
FAM13A affects body fat distribution and adipocyte function
2020-03-19
0.92
Immunogenomic profiling determines responses to combined PARP and PD-1 inhibition in ovarian cancer
2020-03-19
0.92
Olfactory specificity regulates lipid metabolism through neuroendocrine signaling in Caenorhabditis elegans
2020-03-19
1
Rac1 activates non-oxidative pentose phosphate pathway to induce chemoresistance of breast cancer
2020-03-19
0.06
Transcription factor p73 regulates Th1 differentiation
2020-03-19
1
YAP1/TAZ-TEAD transcriptional networks maintain skin homeostasis by regulating cell proliferation and limiting KLF4 activity
2020-03-19
0.67
Abundance of conserved CRISPR-Cas9 target sites within the highly polymorphic genomes of Anopheles and Aedes mosquitoes
2020-03-18
1
Context-dependent dynamics lead to the assembly of functionally distinct microbial communities
2020-03-18
0.80
Environmental remodeling of human gut microbiota and antibiotic resistome in livestock farms
2020-03-18
0.12
Fiber reinforced GelMA hydrogel to induce the regeneration of corneal stroma
2020-03-18
0.03
Full-length transcript characterization of mutation in chronic lymphocytic leukemia reveals downregulation of retained introns
2020-03-18
1
GenomeScope 2.0 and Smudgeplot for reference-free profiling of polyploid genomes
2020-03-18
0.67
Latent periodic process inference from single-cell RNA-seq data
2020-03-18
1
The base of the Assemblage Zone, Karoo Basin, predates the end-Permian marine extinction
2020-03-18
0.67
FGF6 and FGF9 regulate UCP1 expression independent of brown adipogenesis
2020-03-17
0.59
Gating mechanism of hyperpolarization-activated HCN pacemaker channels
2020-03-17
1
Quantifying contributions of chlorofluorocarbon banks to emissions and impacts on the ozone layer and climate
2020-03-17
0.67
Rap1-GTPases control mTORC1 activity by coordinating lysosome organization with amino acid availability
2020-03-17
0.76
Chiral twisting in a bacterial cytoskeletal polymer affects filament size and orientation
2020-03-16
1
Chromatin accessibility promotes hematopoietic and leukemia stem cell activity
2020-03-16
1
Lupus autoantibodies act as positive allosteric modulators at GluN2A-containing NMDA receptors and impair spatial memory
2020-03-16
1
Amino acid levels determine metabolism and CYP450 function of hepatocytes and hepatoma cell lines
2020-03-13
0.14
Amyloid-β42/40 ratio drives tau pathology in 3D human neural cell culture models of Alzheimer’s disease
2020-03-13
1
An amber obligate active site-directed ligand evolution technique for phage display
2020-03-13
1
An engineered oncolytic virus expressing PD-L1 inhibitors activates tumor neoantigen-specific T cell responses
2020-03-13
0.81
Cell-in-the-loop pattern formation with optogenetically emulated cell-to-cell signaling
2020-03-13
0.50
Dynamics of bacterial population growth in biofilms resemble spatial and structural aspects of urbanization
2020-03-13
0.89
Encoding of contextual fear memory in hippocampal–amygdala circuit
2020-03-13
1
Exploration of sensory and spinal neurons expressing gastrin-releasing peptide in itch and pain related behaviors
2020-03-13
0.90
Locally-adapted reproductive photoperiodism determines population vulnerability to climate change in burying beetles
2020-03-13
0.13
Microglia clear neuron-released α-synuclein via selective autophagy and prevent neurodegeneration
2020-03-13
1
Paradoxical activation of the protein kinase-transcription factor ERK5 by ERK5 kinase inhibitors
2020-03-13
0.18
Pretreatment tumor-related leukocytosis misleads positron emission tomography-computed tomography during lymph node staging in gynecological malignancies
2020-03-13
0.08
Small molecule regulated sgRNAs enable control of genome editing in by Cas9
2020-03-13
1
The RNA-binding protein DAZL functions as repressor and activator of mRNA translation during oocyte maturation
2020-03-13
1
Acid ceramidase of macrophages traps herpes simplex virus in multivesicular bodies and protects from severe disease
2020-03-12
0.05
Complex microparticle architectures from stimuli-responsive intrinsically disordered proteins
2020-03-12
1
FAM111A protects replication forks from protein obstacles via its trypsin-like domain
2020-03-12
1
Global plant trait relationships extend to the climatic extremes of the tundra biome
2020-03-12
0.18
Lipidomic and biophysical homeostasis of mammalian membranes counteracts dietary lipid perturbations to maintain cellular fitness
2020-03-12
0.86
Perivascular localization of macrophages in the intestinal mucosa is regulated by Nr4a1 and the microbiome
2020-03-12
0.13
Crystal structure of a lipin/Pah phosphatidic acid phosphatase
2020-03-11
0.71
Exploiting loss of heterozygosity for allele-selective colorectal cancer chemotherapy
2020-03-11
0.18
Pharmacological induction of selective endoplasmic reticulum retention as a strategy for cancer therapy
2020-03-11
0.07
TRIM5α self-assembly and compartmentalization of the HIV-1 viral capsid
2020-03-11
1
Cancer associated fibroblast FAK regulates malignant cell metabolism
2020-03-10
0.20
Diverse nanostructures underlie thin ultra-black scales in butterflies
2020-03-10
1
Integrated proteogenomic deep sequencing and analytics accurately identify non-canonical peptides in tumor immunopeptidomes
2020-03-10
0.04
Social and environmental analysis of food waste abatement via the peer-to-peer sharing economy
2020-03-10
0.90
A critical role of PRDM14 in human primordial germ cell fate revealed by inducible degrons
2020-03-09
0.14
A progesterone biosensor derived from microbial screening
2020-03-09
0.91
Complexation-induced resolution enhancement of 3D-printed hydrogel constructs
2020-03-09
0.68
Cytokinetic bridge triggers de novo lumen formation in vivo
2020-03-09
1
Diffuse X-ray scattering from correlated motions in a protein crystal
2020-03-09
1
Hyperoxia induces glutamine-fuelled anaplerosis in retinal Müller cells
2020-03-09
1
Minimal barriers to invasion during human colorectal tumor growth
2020-03-09
1
Analysis of DNA methylation associates the cystine–glutamate antiporter SLC7A11 with risk of Parkinson’s disease
2020-03-06
0.10
CCN1 is an opsonin for bacterial clearance and a direct activator of Toll-like receptor signaling
2020-03-06
1
Climate adaptation by crop migration
2020-03-06
1
Electron transport chain activity is a predictor and target for venetoclax sensitivity in multiple myeloma
2020-03-06
1
Interplay between DNA damage repair and apoptosis shapes cancer evolution through aneuploidy and microsatellite instability
2020-03-06
1
Major antigenic site B of human influenza H3N2 viruses has an evolving local fitness landscape
2020-03-06
0.75
Maltotriose-based probes for fluorescence and photoacoustic imaging of bacterial infections
2020-03-06
1
Olfactory memory representations are stored in the anterior olfactory nucleus
2020-03-06
0.25
Prioritizing disease and trait causal variants at the locus using functional and genomic features
2020-03-06
1
Resolving dynamics and function of transient states in single enzyme molecules
2020-03-06
0.21
Virtual-freezing fluorescence imaging flow cytometry
2020-03-06
0.02
A signal cascade originated from epidermis defines apical-basal patterning of Arabidopsis shoot apical meristems
2020-03-05
0.86
Anti-angiogenic effects of VEGF stimulation on endothelium deficient in phosphoinositide recycling
2020-03-05
1
Identification of novel breast cancer susceptibility loci in meta-analyses conducted among Asian and European descendants
2020-03-05
0.24
Primary tumors release ITGBL1-rich extracellular vesicles to promote distal metastatic tumor growth through fibroblast-niche formation
2020-03-05
0.05
Structural basis of ligand binding modes at the human formyl peptide receptor 2
2020-03-05
0.08
Trajectory-based differential expression analysis for single-cell sequencing data
2020-03-05
0.42
Vascular progenitors generated from tankyrase inhibitor-regulated naïve diabetic human iPSC potentiate efficient revascularization of ischemic retina
2020-03-05
1
A generalizable 29-mRNA neural-network classifier for acute bacterial and viral infections
2020-03-04
1
Differential DNA methylation of vocal and facial anatomy genes in modern humans
2020-03-04
0.29
Enhanced heat tolerance of viral-infected aphids leads to niche expansion and reduced interspecific competition
2020-03-04
0.55
Inducible cell-to-cell signaling for tunable dynamics in microbial communities
2020-03-04
1
Marker-free carotenoid-enriched rice generated through targeted gene insertion using CRISPR-Cas9
2020-03-04
1
Embracing the dropouts in single-cell RNA-seq analysis
2020-03-03
1
Molecular and cellular determinants of motor asymmetry in zebrafish
2020-03-03
1
Transcriptomic evidence that von Economo neurons are regionally specialized extratelencephalic-projecting excitatory neurons
2020-03-03
1
Nanobody-enabled monitoring of kappa opioid receptor states
2020-03-02
0.86
Serial femtosecond crystallography on in vivo-grown crystals drives elucidation of mosquitocidal Cyt1Aa bioactivation cascade
2020-03-02
0.32
Sex and APOE ε4 genotype modify the Alzheimer’s disease serum metabolome
2020-03-02
0.82
Transient genome-wide interactions of the master transcription factor NLP7 initiate a rapid nitrogen-response cascade
2020-03-02
0.63
Adverse caregiving in infancy blunts neural processing of the mother
2020-02-28
0.86
Annexin A5 as an immune checkpoint inhibitor and tumor-homing molecule for cancer treatment
2020-02-28
0.36
Genome-wide association and multi-omic analyses reveal ACTN2 as a gene linked to heart failure
2020-02-28
1
In vitro ribosome synthesis and evolution through ribosome display
2020-02-28
1
Inhalation of lung spheroid cell secretome and exosomes promotes lung repair in pulmonary fibrosis
2020-02-28
1
Macropinocytosis confers resistance to therapies targeting cancer anabolism
2020-02-28
1
Open access resource for cellular-resolution analyses of corticocortical connectivity in the marmoset monkey
2020-02-28
0.17
Selective EMC subunits act as molecular tethers of intracellular organelles exploited during viral entry
2020-02-28
1
Stem rust resistance in wheat is suppressed by a subunit of the mediator complex
2020-02-28
0.14
Vertical eddy iron fluxes support primary production in the open Southern Ocean
2020-02-28
0.83
A comparative genomics study of 23 Aspergillus species from section Flavi
2020-02-27
0.46
A toxin-antidote CRISPR gene drive system for regional population modification
2020-02-27
1
Cerebellum-enriched protein INPP5A contributes to selective neuropathology in mouse model of spinocerebellar ataxias type 17
2020-02-27
0.23
Gene therapy conversion of striatal astrocytes into GABAergic neurons in mouse models of Huntington’s disease
2020-02-27
0.85
Mass cytometry reveals cellular fingerprint associated with IgE+ peanut tolerance and allergy in early life
2020-02-27
0.42
Mechanically and biologically skin-like elastomers for bio-integrated electronics
2020-02-27
0.08
Multi-resolution localization of causal variants across the genome
2020-02-27
1
Spectral cues are necessary to encode azimuthal auditory space in the mouse superior colliculus
2020-02-27
1
Stimulus dependent transformations between synaptic and spiking receptive fields in auditory cortex
2020-02-27
1
The conserved microRNA miR-34 regulates synaptogenesis via coordination of distinct mechanisms in presynaptic and postsynaptic cells
2020-02-27
1
A comprehensive non-redundant gene catalog reveals extensive within-community intraspecies diversity in the human vagina
2020-02-26
1
Active acetylcholine receptors prevent the atrophy of skeletal muscles and favor reinnervation
2020-02-26
0.07
Candidate silencer elements for the human and mouse genomes
2020-02-26
1
Fatigue-resistant adhesion of hydrogels
2020-02-26
0.71
In vivo imaging of phosphocreatine with artificial neural networks
2020-02-26
0.85
NMT1 and NMT2 are lysine myristoyltransferases regulating the ARF6 GTPase cycle
2020-02-26
1
Response outcomes gate the impact of expectations on perceptual decisions
2020-02-26
0.17
Structure of the G protein chaperone and guanine nucleotide exchange factor Ric-8A bound to Gαi1
2020-02-26
0.79
The anti-viral dynamin family member MxB participates in mitochondrial integrity
2020-02-26
1
The epidermis coordinates thermoresponsive growth through the phyB-PIF4-auxin pathway
2020-02-26
0.10
The role of Mediator and Little Elongation Complex in transcription termination
2020-02-26
0.40
Wounding triggers MIRO-1 dependent mitochondrial fragmentation that accelerates epidermal wound closure through oxidative signaling
2020-02-26
0.10
A silicate dynamo in the early Earth
2020-02-25
0.50
Human occupation of northern India spans the Toba super-eruption ~74,000 years ago
2020-02-25
0.10
Mechanical properties measured by atomic force microscopy define health biomarkers in ageing C. elegans
2020-02-25
0.06
Optogenetic engineering to probe the molecular choreography of STIM1-mediated cell signaling
2020-02-25
0.71
Regulatory sites for splicing in human basal ganglia are enriched for disease-relevant information
2020-02-25
0.12
Silica accelerates the selective hydrogenation of CO2 to methanol on cobalt catalysts
2020-02-25
0.22
The complex genetic landscape of familial MDS and AML reveals pathogenic germline variants
2020-02-25
0.02
Altered chromatin landscape and enhancer engagement underlie transcriptional dysregulation in MED12 mutant uterine leiomyomas
2020-02-24
1
Complexity control by gradient descent in deep networks
2020-02-24
1
Conservation prioritization can resolve the flagship species conundrum
2020-02-24
0.09
Genetic history from the Middle Neolithic to present on the Mediterranean island of Sardinia
2020-02-24
0.36
Multiple network properties overcome random connectivity to enable stereotypic sensory responses
2020-02-24
0.20
Neural cell integration into 3D bioprinted skeletal muscle constructs accelerates restoration of muscle function
2020-02-24
1
Immuno-genomic landscape of osteosarcoma
2020-02-21
1
Klf5 acetylation regulates luminal differentiation of basal progenitors in prostate development and regeneration
2020-02-21
1
Prefrontal parvalbumin interneurons require juvenile social experience to establish adult social behavior
2020-02-21
1
Salmonella Typhimurium biofilm disruption by a human antibody that binds a pan-amyloid epitope on curli
2020-02-21
1
Somatic mosaicism and common genetic variation contribute to the risk of very-early-onset inflammatory bowel disease
2020-02-21
0.12
Structure of the human cation–chloride cotransporter NKCC1 determined by single-particle electron cryo-microscopy
2020-02-21
1
X-ray structure of LeuT in an inward-facing occluded conformation reveals mechanism of substrate release
2020-02-21
0.47
A global assessment of the drivers of threatened terrestrial species richness
2020-02-20
0.33
A serine/threonine protein kinase encoding gene KERNEL NUMBER PER ROW6 regulates maize grain yield
2020-02-20
0.05
Collaborative interactions of heterogenous ribonucleoproteins contribute to transcriptional regulation of sterol metabolism in mice
2020-02-20
1
DNA-based artificial molecular signaling system that mimics basic elements of reception and response
2020-02-20
0.04
Energy consumption and cooperation for optimal sensing
2020-02-20
0.67
Genome of Tripterygium wilfordii and identification of cytochrome P450 involved in triptolide biosynthesis
2020-02-20
0.11
Impact of two of the world's largest protected areas on longline fishery catch rates
2020-02-20
1
Impaired mitophagy links mitochondrial disease to epithelial stress in methylmalonyl-CoA mutase deficiency
2020-02-20
0.10
Microglia control vascular architecture via a TGFβ1 dependent paracrine mechanism linked to tissue mechanics
2020-02-20
1
Migration, hotspots, and dispersal of HIV infection in Rakai, Uganda
2020-02-20
0.39
Naturally-occurring cholesterol analogues in lipid nanoparticles induce polymorphic shape and enhance intracellular delivery of mRNA
2020-02-20
1
Pan-cancer analysis reveals cooperativity of both strands of microRNA that regulate tumorigenesis and patient survival
2020-02-20
0.80
Relaxed sequence constraints favor mutational freedom in idiosyncratic metazoan mitochondrial tRNAs
2020-02-20
1
Tracing tumorigenesis in a solid tumor model at single-cell resolution
2020-02-20
0.10
Ultra-thermostable RNA nanoparticles for solubilizing and high-yield loading of paclitaxel for breast cancer therapy
2020-02-20
1
A molecular gradient along the longitudinal axis of the human hippocampus informs large-scale behavioral systems
2020-02-19
0.15
A molecular switch regulating transcriptional repression and activation of PPARγ
2020-02-19
0.94
Alterations in promoter interaction landscape and transcriptional network underlying metabolic adaptation to diet
2020-02-19
1
Amplification of Duffy binding protein-encoding gene allows Plasmodium vivax to evade host anti-DBP humoral immunity
2020-02-19
0.20
Cellular deconvolution of GTEx tissues powers discovery of disease and cell-type associated regulatory variants
2020-02-19
1
Environmental enrichment ameliorates perinatal brain injury and promotes functional white matter recovery
2020-02-19
1
Immune checkpoint modulation enhances HIV-1 antibody induction
2020-02-19
0.93
Intrinsic neuronal properties represent song and error in zebra finch vocal learning
2020-02-19
1
Topoisomerase 1 cleavage complex enables pattern recognition and inflammation during senescence
2020-02-19
1
A lncRNA-SWI/SNF complex crosstalk controls transcriptional activation at specific promoter regions
2020-02-18
0.11
Autonomic ganglionic injection of α-synuclein fibrils as a model of pure autonomic failure α-synucleinopathy
2020-02-18
0.09
Gut microbiota mediates intermittent-fasting alleviation of diabetes-induced cognitive impairment
2020-02-18
0.08
Simulation-based reconstruction of global bird migration over the past 50,000 years
2020-02-18
0.25
The role of sex work laws and stigmas in increasing HIV risks among sex workers
2020-02-18
0.25
miRNA-1-3p is an early embryonic male sex-determining factor in the Oriental fruit fly Bactrocera dorsalis
2020-02-18
0.43
A computational platform for high-throughput analysis of RNA sequences and modifications by mass spectrometry
2020-02-17
0.19
FOXM1 regulates leukemia stem cell quiescence and survival in MLL-rearranged AML
2020-02-17
1
The first Australian plant foods at Madjedbebe, 65,000–53,000 years ago
2020-02-17
0.11
CASZ1 induces skeletal muscle and rhabdomyosarcoma differentiation through a feed-forward loop with MYOD and MYOG
2020-02-14
1
Capsid protein structure in Zika virus reveals the flavivirus assembly process
2020-02-14
0.08
Evolutionary games with environmental feedbacks
2020-02-14
1
Exceptional subgenome stability and functional divergence in the allotetraploid Ethiopian cereal teff
2020-02-14
1
Immunoproteasome expression is associated with better prognosis and response to checkpoint therapies in melanoma
2020-02-14
0.19
Inflammation mobilizes copper metabolism to promote colon tumorigenesis via an IL-17-STEAP4-XIAP axis
2020-02-14
0.94
MYCN amplification and ATRX mutations are incompatible in neuroblastoma
2020-02-14
1
Mutations in the HPV16 genome induced by APOBEC3 are associated with viral clearance
2020-02-14
0.92
Optoacoustic brain stimulation at submillimeter spatial precision
2020-02-14
0.95
Schizophrenia-related microdeletion causes defective ciliary motility and brain ventricle enlargement via microRNA-dependent mechanisms in mice
2020-02-14
1
Structural basis of mammalian high-mannose N-glycan processing by human gut Bacteroides
2020-02-14
0.63
Structure of formylpeptide receptor 2-Gi complex reveals insights into ligand recognition and signaling
2020-02-14
0.82
Whole-cell imaging of plasma membrane receptors by 3D lattice light-sheet dSTORM
2020-02-14
0.29
A case report of multiple primary prostate tumors with differential drug sensitivity
2020-02-13
1
Epigenetic specifications of host chromosome docking sites for latent Epstein-Barr virus
2020-02-13
0.89
Evapotranspiration depletes groundwater under warming over the contiguous United States
2020-02-13
1
Inference and effects of barcode multiplets in droplet-based single-cell assays
2020-02-13
1
Macrophages employ quorum licensing to regulate collective activation
2020-02-13
1
Siroheme synthase orients substrates for dehydrogenase and chelatase activities in a common active site
2020-02-13
1
ATM and PRDM9 regulate SPO11-bound recombination intermediates during meiosis
2020-02-12
0.95
Deriving disease modules from the compressed transcriptional space embedded in a deep autoencoder
2020-02-12
0.17
Maturation of the human striatal dopamine system revealed by PET and quantitative MRI
2020-02-12
1
Outer membrane protein size and LPS O-antigen define protective antibody targeting to the Salmonella surface
2020-02-12
0.13
Stroma remodeling and reduced cell division define durable response to PD-1 blockade in melanoma
2020-02-12
0.15
Androgen receptor-binding sites are highly mutated in prostate cancer
2020-02-11
0.17
Atomic structures of anthrax toxin protective antigen channels bound to partially unfolded lethal and edema factors
2020-02-11
1
Designing minimal genomes using whole-cell models
2020-02-11
0.17
Discovering the genes mediating the interactions between chronic respiratory diseases in the human interactome
2020-02-10
1
Fasting-induced FGF21 signaling activates hepatic autophagy and lipid degradation via JMJD3 histone demethylase
2020-02-10
0.90
Genome-wide meta-analysis identifies eight new susceptibility loci for cutaneous squamous cell carcinoma
2020-02-10
0.59
H3K4 methylation at active genes mitigates transcription-replication conflicts during replication stress
2020-02-10
0.33
Immunological history governs human stem cell memory CD4 heterogeneity via the Wnt signaling pathway
2020-02-10
0.02
Molecular basis for N-terminal acetylation by human NatE and its modulation by HYPK
2020-02-10
0.60
Neurology-related protein biomarkers are associated with cognitive ability and brain volume in older age
2020-02-10
0.17
Temporal dynamics of protein complex formation and dissociation during human cytomegalovirus infection
2020-02-10
0.81
APOBEC3B-mediated corruption of the tumor cell immunopeptidome induces heteroclitic neoepitopes for cancer immunotherapy
2020-02-07
0.73
CD229 CAR T cells eliminate multiple myeloma and tumor propagating cells without fratricide
2020-02-07
0.93
De novo emergence of adaptive membrane proteins from thymine-rich genomic sequences
2020-02-07
0.88
Determining sequencing depth in a single-cell RNA-seq experiment
2020-02-07
1
Finely tuned eye movements enhance visual acuity
2020-02-07
1
Glycan repositioning of influenza hemagglutinin stem facilitates the elicitation of protective cross-group antibody responses
2020-02-07
0.94
Histone demethylase JMJD1C is phosphorylated by mTOR to activate de novo lipogenesis
2020-02-07
1
IGF1-mediated human embryonic stem cell self-renewal recapitulates the embryonic niche
2020-02-07
0.03
Increased circulating levels of Factor H-Related Protein 4 are strongly associated with age-related macular degeneration
2020-02-07
0.02
Influenza A viruses are transmitted via the air from the nasal respiratory epithelium of ferrets
2020-02-07
0.71
Minimally disruptive optical control of protein tyrosine phosphatase 1B
2020-02-07
1
Single cell analyses reveal contrasting life strategies of the two main nitrifiers in the ocean
2020-02-07
0.17
The COMET toolkit for composing customizable genetic programs in mammalian cells
2020-02-07
1
A combination strategy targeting enhancer plasticity exerts synergistic lethality against BETi-resistant leukemia cells
2020-02-06
0.92
Bacillus cereus non-haemolytic enterotoxin activates the NLRP3 inflammasome
2020-02-06
0.05
Characterizing chromatin landscape from aggregate and single-cell genomic assays using flexible duration modeling
2020-02-06
1
Complete structure of the chemosensory array core signalling unit in an E. coli minicell strain
2020-02-06
0.33
Genetic screens in isogenic mammalian cell lines without single cell cloning
2020-02-06
1
Photoswitching mechanism of a fluorescent protein revealed by time-resolved crystallography and transient absorption spectroscopy
2020-02-06
0.03
Regulation of lipid saturation without sensing membrane fluidity
2020-02-06
0.20
Separability and geometry of object manifolds in deep neural networks
2020-02-06
0.63
Sexual-dimorphism in human immune system aging
2020-02-06
1
A deep learning system accurately classifies primary and metastatic cancers using passenger mutation patterns
2020-02-05
0.33
Combined burden and functional impact tests for cancer driver discovery using DriverPower
2020-02-05
0.39
Divergent mutational processes distinguish hypoxic and normoxic tumours
2020-02-05
0.23
Estimating growth patterns and driver effects in tumor evolution from individual samples
2020-02-05
1
Friendship paradox biases perceptions in directed networks
2020-02-05
1
Genomic footprints of activated telomere maintenance mechanisms in cancer
2020-02-05
0.33
High-coverage whole-genome analysis of 1220 cancers reveals hundreds of genes deregulated by rearrangement-mediated -regulatory alterations
2020-02-05
0.31
Inferring structural variant cancer cell fraction
2020-02-05
0.33
Integrative pathway enrichment analysis of multivariate omics data
2020-02-05
0.37
MTR4 drives liver tumorigenesis by promoting cancer metabolic switch through alternative splicing
2020-02-05
0.04
Pathway and network analysis of more than 2500 whole cancer genomes
2020-02-05
0.41
ProtCID: a data resource for structural information on protein interactions
2020-02-05
1
Ranking environmental degradation trends of plastic marine debris based on physical properties and molecular structure
2020-02-05
1
Reconstructing evolutionary trajectories of mutation signature activities in cancer using TrackSig
2020-02-05
0.33
Regulation of heterotopic ossification by monocytes in a mouse model of aberrant wound healing
2020-02-05
1
mTORC1 coordinates an immediate unfolded protein response-related transcriptome in activated B cells preceding antibody secretion
2020-02-05
1
A system wide approach to managing zoo collections for visitor attendance and in situ conservation
2020-02-04
0.21
Compartmentalized microbes and co-cultures in hydrogels for on-demand bioproduction and preservation
2020-02-04
1
DNA unwinding mechanism of a eukaryotic replicative CMG helicase
2020-02-04
1
Human large-scale cooperation as a product of competition between cultural groups
2020-02-04
1
Multicomponent molecular memory
2020-02-04
1
Nitric oxide orchestrates metabolic rewiring in M1 macrophages by targeting aconitase 2 and pyruvate dehydrogenase
2020-02-04
0.86
Spatiotemporal functional organization of excitatory synaptic inputs onto macaque V1 neurons
2020-02-04
0.29
Sustained treatment of retinal vascular diseases with self-aggregating sunitinib microparticles
2020-02-04
1
The megabiota are disproportionately important for biosphere functioning
2020-02-04
0.60
Tracking regional brain growth up to age 13 in children born term and very preterm
2020-02-04
0.18
A phosphorylation-based switch controls TAA1-mediated auxin biosynthesis in plants
2020-02-03
0.08
A rare gain of function mutation in a wheat tandem kinase confers resistance to powdery mildew
2020-02-03
0.17
Chronic activation of endothelial MAPK disrupts hematopoiesis via NFKB dependent inflammatory stress reversible by SCGF
2020-02-03
1
Exceptionally low likelihood of Alzheimer’s dementia in APOE2 homozygotes from a 5,000-person neuropathological study
2020-02-03
0.98
Two-stage electro–mechanical coupling of a KV channel in voltage-dependent activation
2020-02-03
0.73
A MAFG-lncRNA axis links systemic nutrient abundance to hepatic glucose metabolism
2020-01-31
0.23
Bempegaldesleukin selectively depletes intratumoral Tregs and potentiates T cell-mediated cancer therapy
2020-01-31
1
Distinct effects of general anesthetics on lung metastasis mediated by IL-6/JAK/STAT3 pathway in mouse models
2020-01-31
1
Early life experiences selectively mature learning and memory abilities
2020-01-31
1
Elucidating target specificity of the taccalonolide covalent microtubule stabilizers employing a combinatorial chemical approach
2020-01-31
1
Fast temporal dynamics and causal relevance of face processing in the human temporal cortex
2020-01-31
0.83
Fibrinogen induces neural stem cell differentiation into astrocytes in the subventricular zone via BMP signaling
2020-01-31
0.13
Global meta-analysis shows pervasive phosphorus limitation of aboveground plant production in natural terrestrial ecosystems
2020-01-31
0.29
Human and mouse essentiality screens as a resource for disease gene discovery
2020-01-31
0.20
Monitoring spatiotemporal changes in chaperone-mediated autophagy in vivo
2020-01-31
1
Non-invasive recording from the human olfactory bulb
2020-01-31
0.40
Persistence of adoptively transferred T cells with a kinetically engineered IL-2 receptor agonist
2020-01-31
1
Surface protein imputation from single cell transcriptomes by deep neural networks
2020-01-31
0.75
The in vivo genetic program of murine primordial lung epithelial progenitors
2020-01-31
0.98
Tissue mechanics drives regeneration of a mucociliated epidermis on the surface of Xenopus embryonic aggregates
2020-01-31
0.75
Understanding the structural basis of HIV-1 restriction by the full length double-domain APOBEC3G
2020-01-31
0.59
A RAF-SnRK2 kinase cascade mediates early osmotic stress signaling in higher plants
2020-01-30
0.11
Carbon doping switching on the hydrogen adsorption activity of NiO for hydrogen evolution reaction
2020-01-30
0.73
Comprehensive T cell repertoire characterization of non-small cell lung cancer
2020-01-30
1
Imaging brain activity during complex social behaviors in Drosophila with Flyception2
2020-01-30
1
In cellulo crystallization of Trypanosoma brucei IMP dehydrogenase enables the identification of genuine co-factors
2020-01-30
0.35
Loss-of-function mutations in UDP-Glucose 6-Dehydrogenase cause recessive developmental epileptic encephalopathy
2020-01-30
0.25
Macrophages directly contribute collagen to scar formation during zebrafish heart regeneration and mouse heart repair
2020-01-30
0.14
Microchannel network hydrogel induced ischemic blood perfusion connection
2020-01-30
0.05
Molecular signatures of aneuploidy-driven adaptive evolution
2020-01-30
0.93
Optogenetic regulation of endogenous proteins
2020-01-30
0.47
Physical activity and risks of breast and colorectal cancer: a Mendelian randomisation analysis
2020-01-30
0.40
Probing the physical limits of reliable DNA data retrieval
2020-01-30
1
Structure of the prefusion-locking broadly neutralizing antibody RVC20 bound to the rabies virus glycoprotein
2020-01-30
0.15
Tumor heterogeneity and clonal cooperation influence the immune selection of IFN-γ-signaling mutant cancer cells
2020-01-30
1
Positive surface charge of GluN1 N-terminus mediates the direct interaction with EphB2 and NMDAR mobility
2020-01-29
1
Single-cell transcriptomics identifies CD44 as a marker and regulator of endothelial to haematopoietic transition
2020-01-29
0.06
Tissue pO2 distributions in xenograft tumors dynamically imaged by Cherenkov-excited phosphorescence during fractionated radiation therapy
2020-01-29
0.85
Vaccination with CD47 deficient tumor cells elicits an antitumor immune response in mice
2020-01-29
0.38
mTORC2-AKT signaling to ATP-citrate lyase drives brown adipogenesis and de novo lipogenesis
2020-01-29
1
Blood-triggered generation of platinum nanoparticle functions as an anti-cancer agent
2020-01-28
0.13
Eukaryotic transcription factors can track and control their target genes using DNA antennas
2020-01-28
0.44
Fingerprint of rice paddies in spatial–temporal dynamics of atmospheric methane concentration in monsoon Asia
2020-01-28
0.63
Genome-wide rare variant analysis for thousands of phenotypes in over 70,000 exomes from two cohorts
2020-01-28
1
HSP90A inhibition promotes anti-tumor immunity by reversing multi-modal resistance and stem-like property of immune-refractory tumors
2020-01-28
0.28
Hydrogen sulfide stimulates Mycobacterium tuberculosis respiration, growth and pathogenesis
2020-01-28
0.58
Longitudinal assessment of tumor development using cancer avatars derived from genetically engineered pluripotent stem cells
2020-01-28
1
Physical and behavioral adaptations to prevent overheating of the living wings of butterflies
2020-01-28
1
Systemic infection facilitates transmission of Pseudomonas aeruginosa in mice
2020-01-28
0.80
TrkA undergoes a tetramer-to-dimer conversion to open TrkH which enables changes in membrane potential
2020-01-28
1
Genetically stable poliovirus vectors activate dendritic cells and prime antitumor CD8 T cell immunity
2020-01-27
1
Habitat compression and ecosystem shifts as potential links between marine heatwave and record whale entanglements
2020-01-27
1
Integrative analysis reveals RNA G-quadruplexes in UTRs are selectively constrained and enriched for functional associations
2020-01-27
1
Lymphatic endothelial cells prime naïve CD8+ T cells into memory cells under steady-state conditions
2020-01-27
0.14
Microscaled proteogenomic methods for precision oncology
2020-01-27
1
Nuthatches vary their alarm calls based upon the source of the eavesdropped signals
2020-01-27
0.67
White blood cell and cell-free DNA analyses for detection of residual disease in gastric cancer
2020-01-27
0.39
African-centric TP53 variant increases iron accumulation and bacterial pathogenesis but improves response to malaria toxin
2020-01-24
1
Atomically resolved Au52Cu72(SR)55 nanoalloy reveals Marks decahedron truncation and Penrose tiling surface
2020-01-24
0.22
CD73 on cancer-associated fibroblasts enhanced by the A-mediated feedforward circuit enforces an immune checkpoint
2020-01-24
0.80
Dispersion fields reveal the compositional structure of South American vertebrate assemblages
2020-01-24
0.17
Disruption of auto-inhibition underlies conformational signaling of ASIC1a to induce neuronal necroptosis
2020-01-24
0.11
Disruption of the HIV-1 Envelope allosteric network blocks CD4-induced rearrangements
2020-01-24
1
Distinct temporal integration of noradrenaline signaling by astrocytic second messengers during vigilance
2020-01-24
0.11
Dstyk mutation leads to congenital scoliosis-like vertebral malformations in zebrafish via dysregulated mTORC1/TFEB pathway
2020-01-24
0.06
Erythroid differentiation regulator-1 induced by microbiota in early life drives intestinal stem cell proliferation and regeneration
2020-01-24
0.96
Extensive rewiring of the EGFR network in colorectal cancer cells expressing transforming levels of KRASG13D
2020-01-24
0.01
Impaired neuronal sodium channels cause intranodal conduction failure and reentrant arrhythmias in human sinoatrial node
2020-01-24
0.86
Interrogation of enhancer function by enhancer-targeting CRISPR epigenetic editing
2020-01-24
1
Isolation of Angola-like Marburg virus from Egyptian rousette bats from West Africa
2020-01-24
0.31
Kindlin-2 modulates MafA and β-catenin expression to regulate β-cell function and mass in mice
2020-01-24
0.49
Nr4a1 suppresses cocaine-induced behavior via epigenetic regulation of homeostatic target genes
2020-01-24
1
PTH induces bone loss via microbial-dependent expansion of intestinal TNF T cells and Th17 cells
2020-01-24
1
Single-cell analysis reveals new evolutionary complexity in uveal melanoma
2020-01-24
1
Spatial attention enhances network, cellular and subthreshold responses in mouse visual cortex
2020-01-24
1
Super-resolution microscopy compatible fluorescent probes reveal endogenous glucagon-like peptide-1 receptor distribution and dynamics
2020-01-24
0.08
Targeting glutamine metabolism slows soft tissue sarcoma growth
2020-01-24
1
The RNA-binding protein AKAP8 suppresses tumor metastasis by antagonizing EMT-associated alternative splicing
2020-01-24
1
The proteasome 19S cap and its ubiquitin receptors provide a versatile recognition platform for substrates
2020-01-24
1
YAP-dependent necrosis occurs in early stages of Alzheimer’s disease and regulates mouse model pathology
2020-01-24
0.04
Alternative transcription cycle for bacterial RNA polymerase
2020-01-23
1
Chaperone mediated detection of small molecule target binding in cells
2020-01-23
1
Chromosome arm aneuploidies shape tumour evolution and drug response
2020-01-23
0.08
Dissecting transcriptomic signatures of neuronal differentiation and maturation using iPSCs
2020-01-23
0.97
Genetic deletion of mast cell serotonin synthesis prevents the development of obesity and insulin resistance
2020-01-23
0.25
Nedd4 ubiquitylates VDAC2/3 to suppress erastin-induced ferroptosis in melanoma
2020-01-23
0.09
Non-canonical Wnt signalling regulates scarring in biliary disease via the planar cell polarity receptors
2020-01-23
0.05
Noncoding mutations target cis-regulatory elements of the FOXA1 plexus in prostate cancer
2020-01-23
0.02
Peptidoglycan reshaping by a noncanonical peptidase for helical cell shape in Campylobacter jejuni
2020-01-23
0.31
The Medical Genome Reference Bank contains whole genome and phenotype data of 2570 healthy elderly
2020-01-23
0.11
WASP family proteins regulate the mobility of the B cell receptor during signaling activation
2020-01-23
0.94
Persistent activation of central amygdala CRF neurons helps drive the immediate fear extinction deficit
2020-01-22
0.88
Structural basis of subtype-selective competitive antagonism for GluN2C/2D-containing NMDA receptors
2020-01-22
0.50
The negative cofactor 2 complex is a key regulator of drug resistance in Aspergillus fumigatus
2020-01-22
0.17
Alloying design of biodegradable zinc as promising bone implants for load-bearing applications
2020-01-21
0.11
FAM222A encodes a protein which accumulates in plaques in Alzheimer’s disease
2020-01-21
0.90
Golgi organization is regulated by proteasomal degradation
2020-01-21
0.09
Haplotyping the Vitis collinear core genome with rhAmpSeq improves marker transferability in a diverse genus
2020-01-21
1
Non-invasive characterization of human bone marrow stimulation and reconstitution by cell-free messenger RNA sequencing
2020-01-21
1
Structure-guided design of pure orthosteric inhibitors of αIIbβ3 that prevent thrombosis but preserve hemostasis
2020-01-21
0.80
Androgen deprivation upregulates SPINK1 expression and potentiates cellular plasticity in prostate cancer
2020-01-20
0.40
Distinctive phenotypes and functions of innate lymphoid cells in human decidua during early pregnancy
2020-01-20
0.12
Economic system justification predicts muted emotional responses to inequality
2020-01-20
0.75
Mutational signatures in tumours induced by high and low energy radiation in Trp53 deficient mice
2020-01-20
0.62
Precapillary sphincters maintain perfusion in the cerebral cortex
2020-01-20
0.06
A transcomplementing gene drive provides a flexible platform for laboratory investigation and potential field deployment
2020-01-17
1
Auxin-dependent control of a plasmodesmal regulator creates a negative feedback loop modulating lateral root emergence
2020-01-17
0.78
Cryo-EM structure of the respiratory syncytial virus RNA polymerase
2020-01-17
1
Functional brain architecture is associated with the rate of tau accumulation in Alzheimer’s disease
2020-01-17
0.90
Hepatic TET3 contributes to type-2 diabetes by inducing the HNF4α fetal isoform
2020-01-17
0.77
Lamellar architectures in stiff biomaterials may not always be templates for enhancing toughness in composites
2020-01-17
1
Large-scale lipid analysis with C=C location and sn-position isomer resolving power
2020-01-17
0.10
MUC1-C regulates lineage plasticity driving progression to neuroendocrine prostate cancer
2020-01-17
0.87
Machine learning can identify newly diagnosed patients with CLL at high risk of infection
2020-01-17
0.05
Polypeptide templating for designer hierarchical materials
2020-01-17
1
Rad50 zinc hook functions as a constitutive dimerization module interchangeable with SMC hinge
2020-01-17
0.07
Rapid and deep-scale ubiquitylation profiling for biology and translational research
2020-01-17
0.93
TRIM25 promotes the cell survival and growth of hepatocellular carcinoma through targeting Keap1-Nrf2 pathway
2020-01-17
0.10
The molecular basis of pyrazinamide activity on Mycobacterium tuberculosis PanD
2020-01-17
1
The origins of acoustic communication in vertebrates
2020-01-17
0.75
β4GALT1 controls β1 integrin function to govern thrombopoiesis and hematopoietic stem cell homeostasis
2020-01-17
0.83
A Wnt-mediated transformation of the bone marrow stromal cell identity orchestrates skeletal regeneration
2020-01-16
0.91
A network analysis to identify mediators of germline-driven differences in breast cancer prognosis
2020-01-16
0.21
Edible unclonable functions
2020-01-16
0.25
Electrophysiological dynamics of antagonistic brain networks reflect attentional fluctuations
2020-01-16
0.64
Epigenetic reprogramming at estrogen-receptor binding sites alters 3D chromatin landscape in endocrine-resistant breast cancer
2020-01-16
0.11
Genomic programming of IRF4-expressing human Langerhans cells
2020-01-16
0.36
Holographic detection of nanoparticles using acoustically actuated nanolenses
2020-01-16
0.50
Interaction variability shapes succession of synthetic microbial ecosystems
2020-01-16
0.60
Maximizing the ovarian reserve in mice by evading LINE-1 genotoxicity
2020-01-16
1
Melanoblast transcriptome analysis reveals pathways promoting melanoma metastasis
2020-01-16
1
Microglial activation increases cocaine self-administration following adolescent nicotine exposure
2020-01-16
1
Temporal inhibition of autophagy reveals segmental reversal of ageing with increased cancer risk
2020-01-16
0.20
The epichaperome is a mediator of toxic hippocampal stress and leads to protein connectivity-based dysfunction
2020-01-16
1
Acquisition, transmission and strain diversity of human gut-colonizing crAss-like phages
2020-01-15
1
Anti-BCMA chimeric antigen receptors with fully human heavy-chain-only antigen recognition domains
2020-01-15
1
Intratumoral heterogeneity and clonal evolution in liver cancer
2020-01-15
0.91
Irp2 regulates insulin production through iron-mediated Cdkal1-catalyzed tRNA modification
2020-01-15
0.44
Tree species traits affect which natural enemies drive the Janzen-Connell effect in a temperate forest
2020-01-15
0.17
Warming of hot extremes alleviated by expanding irrigation
2020-01-15
0.11
A mosquito salivary protein promotes flavivirus transmission by activation of autophagy
2020-01-14
0.08
Dorsal root ganglion macrophages contribute to both the initiation and persistence of neuropathic pain
2020-01-14
0.94
Dynamic MAIT cell response with progressively enhanced innateness during acute HIV-1 infection
2020-01-14
0.58
Dynamic organelle distribution initiates actin-based spindle migration in mouse oocytes
2020-01-14
0.97
Environmental DNA reveals seasonal shifts and potential interactions in a marine community
2020-01-14
1
Integrated single cell analysis of blood and cerebrospinal fluid leukocytes in multiple sclerosis
2020-01-14
0.21
Phase separation of TPX2 enhances and spatially coordinates microtubule nucleation
2020-01-14
1
Rare copy number variants in over 100,000 European ancestry subjects reveal multiple disease associations
2020-01-14
0.98
A set of monomeric near-infrared fluorescent proteins for multicolor imaging across scales
2020-01-13
0.58
Annexin-V stabilizes membrane defects by inducing lipid phase transition
2020-01-13
0.83
Antimicrobial resistant enteric bacteria are widely distributed amongst people, animals and the environment in Tanzania
2020-01-13
0.45
Distinct DNA repair pathways cause genomic instability at alternative DNA structures
2020-01-13
1
Resolving kinetic intermediates during the regulated assembly and disassembly of fusion pores
2020-01-13
1
SUMOylation inhibitors synergize with FXR agonists in combating liver fibrosis
2020-01-13
0.08
Sestrin prevents atrophy of disused and aging muscles by integrating anabolic and catabolic signals
2020-01-13
0.23
Sestrins are evolutionarily conserved mediators of exercise benefits
2020-01-13
1
The evolution of sexual signaling is linked to odorant receptor tuning in perfume-collecting orchid bees
2020-01-13
0.43
ADAR1 mediated regulation of neural crest derived melanocytes and Schwann cell development
2020-01-10
0.08
Arf1-mediated lipid metabolism sustains cancer cells and its ablation induces anti-tumor immune responses in mice
2020-01-10
1
Clonal kinetics and single-cell transcriptional profiling of CAR-T cells in patients undergoing CD19 CAR-T immunotherapy
2020-01-10
1
Comparative therapeutic efficacy of remdesivir and combination lopinavir, ritonavir, and interferon beta against MERS-CoV
2020-01-10
1
Discovery of bilaterian-type through-guts in cloudinomorphs from the terminal Ediacaran Period
2020-01-10
0.88
Generation of mesenchyme free intestinal organoids from human induced pluripotent stem cells
2020-01-10
1
Graded intrafillable architecture-based iontronic pressure sensor with ultra-broad-range high sensitivity
2020-01-10
0.15
Macropinocytosis drives T cell growth by sustaining the activation of mTORC1
2020-01-10
1
Microengineered human blood–brain barrier platform for understanding nanoparticle transport mechanisms
2020-01-10
0.90
Neutrophil microvesicles drive atherosclerosis by delivering miR-155 to atheroprone endothelium
2020-01-10
0.02
O-GlcNAc transferase inhibits visceral fat lipolysis and promotes diet-induced obesity
2020-01-10
1
Plant metabolism of nematode pheromones mediates plant-nematode interactions
2020-01-10
1
Structural basis for adhesion G protein-coupled receptor Gpr126 function
2020-01-10
1
ASCOT identifies key regulators of neuronal subtype-specific splicing
2020-01-09
1
Genome-wide CRISPR screen identifies host dependency factors for influenza A virus infection
2020-01-09
0.49
Genome-wide association and Mendelian randomisation analysis provide insights into the pathogenesis of heart failure
2020-01-09
0.55
Identification of distinct maturation steps involved in human 40S ribosomal subunit biosynthesis
2020-01-09
0.17
Image-guided neural activity manipulation with a paramagnetic drug
2020-01-09
1
Inhibiting bacterial cooperation is an evolutionarily robust anti-biofilm strategy
2020-01-09
0.04
Structural basis for itraconazole-mediated NPC1 inhibition
2020-01-09
1
The nuclear pore complex prevents sister chromatid recombination during replicative senescence
2020-01-09
0.29
Zinc-finger protein CNBP alters the 3-D structure of lncRNA Braveheart in solution
2020-01-09
0.43
5-fluorocytosine resistance is associated with hypermutation and alterations in capsule biosynthesis in 
2020-01-08
1
Dopamine transients do not act as model-free prediction errors during associative learning
2020-01-08
0.96
Forest management in southern China generates short term extensive carbon sequestration
2020-01-08
0.16
Integrin-specific hydrogels modulate transplanted human bone marrow-derived mesenchymal stem cell survival, engraftment, and reparative activities
2020-01-08
1
Neutrophil extracellular trap-associated RNA and LL37 enable self-amplifying inflammation in psoriasis
2020-01-08
0.11
Predicting optical coherence tomography-derived diabetic macular edema grades from fundus photographs using deep learning
2020-01-08
0.56
Prox1-positive cells monitor and sustain the murine intestinal epithelial cholinergic niche
2020-01-08
0.75
Soil bacterial diversity mediated by microscale aqueous-phase processes across biomes
2020-01-08
0.25
Symbiont population control by host-symbiont metabolic interaction in Symbiodiniaceae-cnidarian associations
2020-01-08
1
The mechanistic and functional profile of the therapeutic anti-IgE antibody ligelizumab differs from omalizumab
2020-01-08
0.30
ULK1 phosphorylates Exo70 to suppress breast cancer metastasis
2020-01-08
0.17
Automated mass spectrometry imaging of over 2000 proteins from tissue sections at 100-μm spatial resolution
2020-01-07
1
BCL9 provides multi-cellular communication properties in colorectal cancer by interacting with paraspeckle proteins
2020-01-07
0.73
Different ways to transport ammonia in human and Mycobacterium tuberculosis NAD+ synthetases
2020-01-07
0.83
Fungal community assembly in drought-stressed sorghum shows stochasticity, selection, and universal ecological dynamics
2020-01-07
1
Identification of osteoclast-osteoblast coupling factors in humans reveals links between bone and energy metabolism
2020-01-07
0.88
Imaging of fluorescence anisotropy during photoswitching provides a simple readout for protein self-association
2020-01-07
1
Immune-mediated genetic pathways resulting in pulmonary function impairment increase lung cancer susceptibility
2020-01-07
0.40
Ketamine disinhibits dendrites and enhances calcium signals in prefrontal dendritic spines
2020-01-07
1
Long-read sequencing reveals genomic structural variations that underlie creation of quality protein maize
2020-01-07
0.27
Microparticle traction force microscopy reveals subcellular force exertion patterns in immune cell–target interactions
2020-01-07
1
Modulation of brain cation-Cl− cotransport via the SPAK kinase inhibitor ZT-1a
2020-01-07
0.58
Pharmacological polyamine catabolism upregulation with methionine salvage pathway inhibition as an effective prostate cancer therapy
2020-01-07
1
Quantitative live cell imaging reveals influenza virus manipulation of Rab11A transport through reduced dynein association
2020-01-07
1
Recording mobile DNA in the gut microbiota using an CRISPR-Cas spacer acquisition platform
2020-01-07
1
Single-cell analysis based dissection of clonality in myelofibrosis
2020-01-07
0.05
Single-dose bNAb cocktail or abbreviated ART post-exposure regimens achieve tight SHIV control without adaptive immunity
2020-01-07
1
TGF-β induces ST2 and programs ILC2 development
2020-01-07
0.74
The RepID–CRL4 ubiquitin ligase complex regulates metaphase to anaphase transition via BUB3 degradation
2020-01-07
1
Time-dependent solid-state molecular motion and colour tuning of host-guest systems by organic solvents
2020-01-07
0.06
Transmission of tauopathy strains is independent of their isoform composition
2020-01-07
1
U1 snRNP regulates cancer cell migration and invasion in vitro
2020-01-07
1
Ventromedial prefrontal cortex compression during concept learning
2020-01-07
0.33
A shared genetic basis of mimicry across swallowtail butterflies points to ancestral co-option of doublesex
2020-01-03
1
An in vitro platform for engineering and harnessing modular polyketide synthases
2020-01-03
1
CaSpER identifies and visualizes CNV events by integrative analysis of single-cell or bulk RNA-sequencing data
2020-01-03
1
Epigenetics meets proteomics in an epigenome-wide association study with circulating blood plasma protein traits
2020-01-03
0.03
Fast and accurate sCMOS noise correction for fluorescence microscopy
2020-01-03
1
Gastric squamous-columnar junction contains a large pool of cancer-prone immature osteopontin responsive Lgr5−CD44+ cells
2020-01-03
0.93
Interpreting pathways to discover cancer driver genes with Moonlight
2020-01-03
0.26
Mapping axon initial segment structure and function by multiplexed proximity biotinylation
2020-01-03
0.92
Polydiacetylene-based ultrastrong bioorthogonal Raman probes for targeted live-cell Raman imaging
2020-01-03
0.15
Rational design of universal immunotherapy for TfR1-tropic arenaviruses
2020-01-03
0.30
An early phase of instructive plasticity before the typical onset of sensory experience
2020-01-02
1
B cell-intrinsic epigenetic modulation of antibody responses by dietary fiber-derived short-chain fatty acids
2020-01-02
0.89
Forces during cellular uptake of viruses and nanoparticles at the ventral side
2020-01-02
0.20
Gut stem cell aging is driven by mTORC1 via a p38 MAPK-p53 pathway
2020-01-02
0.21
Identification of recurrent FHL2-GLI2 oncogenic fusion in sclerosing stromal tumors of the ovary
2020-01-02
0.89
In vivo functional analysis of non-conserved human lncRNAs associated with cardiometabolic traits
2020-01-02
0.75
MAP3Kinase-dependent SnRK2-kinase activation is required for abscisic acid signal transduction and rapid osmotic stress response
2020-01-02
0.91
Measuring local-directional resolution and local anisotropy in cryo-EM maps
2020-01-02
0.20
Retinoic acid degradation shapes zonal development of vestibular organs and sensitivity to transient linear accelerations
2020-01-02
0.86
Sertoli cell ablation and replacement of the spermatogonial niche in mouse
2020-01-02
0.88
A mitochondrial megachannel resides in monomeric F1FO ATP synthase
2019-12-20
1
Agreement between two large pan-cancer CRISPR-Cas9 gene dependency data sets
2019-12-20
0.54
Controllability governs the balance between Pavlovian and instrumental action selection
2019-12-20
1
Definition of functionally and structurally distinct repressive states in the nuclear receptor PPARγ
2019-12-20
1
Descending motor circuitry required for NT-3 mediated locomotor recovery after spinal cord injury in mice
2019-12-20
1
El Niño-Southern oscillation and under-5 diarrhea in Botswana
2019-12-20
0.83
Evolution of satellite plasmids can prolong the maintenance of newly acquired accessory genes in bacteria
2019-12-20
1
Forty-five patient-derived xenografts capture the clinical and biological heterogeneity of Wilms tumor
2019-12-20
1
Novel approach reveals genomic landscapes of single-strand DNA breaks with nucleotide resolution in human cells
2019-12-20
0.12
PBRM1 acts as a p53 lysine-acetylation reader to suppress renal tumor growth
2019-12-20
1
Polyanions provide selective control of APC/C interactions with the activator subunit
2019-12-20
1
Profiling of the plasma proteome across different stages of human heart failure
2019-12-20
0.46
Relaxed purifying selection in autopolyploids drives transposable element over-accumulation which provides variants for local adaptation
2019-12-20
0.20
Standing genetic variation fuels rapid adaptation to ocean acidification
2019-12-20
0.50
Structural basis for Fullerene geometry in a human endogenous retrovirus capsid
2019-12-20
0.04
The METLIN small molecule dataset for machine learning-based retention time prediction
2019-12-20
1
The anticipation of events in time
2019-12-20
0.42
scRNA-seq in medulloblastoma shows cellular heterogeneity and lineage expansion support resistance to SHH inhibitor therapy
2019-12-20
0.74
Edematous severe acute malnutrition is characterized by hypomethylation of DNA
2019-12-19
0.61
Enhancing plasticity in central networks improves motor and sensory recovery after nerve damage
2019-12-19
1
Multi-functional genome-wide CRISPR system for high throughput genotype–phenotype mapping
2019-12-19
0.93
Natural selection favoring more transmissible HIV detected in United States molecular transmission network
2019-12-19
1
Small molecules that inhibit TNF signalling by stabilising an asymmetric form of the trimer
2019-12-19
0.17
Transforming Growth Factor-beta signaling in αβ thymocytes promotes negative selection
2019-12-19
0.04
A short translational ramp determines the efficiency of protein synthesis
2019-12-18
0.86
Glacial–interglacial Nd isotope variability of North Atlantic Deep Water modulated by North American ice sheet
2019-12-18
0.83
MLL-AF9 initiates transformation from fast-proliferating myeloid progenitors
2019-12-18
0.90
SKP2 attenuates autophagy through Beclin1-ubiquitination and its inhibition reduces MERS-Coronavirus infection
2019-12-18
0.04
Stress sensitization among severely neglected children and protection by social enrichment
2019-12-18
0.50
A transposable element insertion is associated with an alternative life history strategy
2019-12-17
0.14
Discovery of a chemical probe for PRDM9
2019-12-17
0.19
In vitro implementation of robust gene regulation in a synthetic biomolecular integral controller
2019-12-17
1
Multi-scale imaging and analysis identify pan-embryo cell dynamics of germlayer formation in zebrafish
2019-12-17
0.17
Sexual dimorphism and the role of estrogen in the immune microenvironment of liver metastases
2019-12-17
0.09
Single-nuclei RNA-seq on human retinal tissue provides improved transcriptome profiling
2019-12-17
1
Wireless, battery-free, fully implantable multimodal and multisite pacemakers for applications in small animal models
2019-12-17
0.94
A bacterial gene-drive system efficiently edits and inactivates a high copy number antibiotic resistance locus
2019-12-16
1
An epitranscriptomic mechanism underlies selective mRNA translation remodelling in melanoma persister cells
2019-12-16
0.06
Chaperone biomarkers of lifespan and penetrance track the dosages of many other proteins
2019-12-16
1
Chemical-genetic profiling reveals limited cross-resistance between antimicrobial peptides with different modes of action
2019-12-16
0.03
Classification of mouse B cell types using surfaceome proteotype maps
2019-12-16
0.10
Colloidal silver diphosphide (AgP2) nanocrystals as low overpotential catalysts for CO2 reduction to tunable syngas
2019-12-16
0.83
Deglacial water-table decline in Southern California recorded by noble gas isotopes
2019-12-16
1
Droplet Tn-Seq combines microfluidics with Tn-Seq for identifying complex single-cell phenotypes
2019-12-16
1
Impacts of Zika emergence in Latin America on endemic dengue transmission
2019-12-16
1
Insights into malaria susceptibility using genome-wide data on 17,000 individuals from Africa, Asia and Oceania
2019-12-16
0.01
Recurrent PTPRT/JAK2 mutations in lung adenocarcinoma among African Americans
2019-12-16
1
Task complexity interacts with state-space uncertainty in the arbitration between model-based and model-free learning
2019-12-16
0.25
The role of prefrontal cortex in the control of feature attention in area V4
2019-12-16
1
The upper-airway microbiota and loss of asthma control among asthmatic children
2019-12-16
0.98
BEN-solo factors partition active chromatin to ensure proper gene activation in Drosophila
2019-12-13
0.33
Computational modeling demonstrates that glioblastoma cells can survive spatial environmental challenges through exploratory adaptation
2019-12-13
1
Engineering protein assemblies with allosteric control via monomer fold-switching
2019-12-13
0.13
Examining multiple cellular pathways at once using multiplex hextuple luciferase assaying
2019-12-13
0.92
Functional significance of U2AF1 S34F mutations in lung adenocarcinomas
2019-12-13
0.98
Metabolomics analysis of human acute graft-versus-host disease reveals changes in host and microbiota-derived metabolites
2019-12-13
0.17
Molecular determinants of nephron vascular specialization in the kidney
2019-12-13
1
Obesity and disease severity magnify disturbed microbiome-immune interactions in asthma patients
2019-12-13
0.11
miRNA142-3p targets Tet2 and impairs Treg differentiation and stability in models of type 1 diabetes
2019-12-13
0.25
A truncating mutation in the autophagy gene UVRAG drives inflammation and tumorigenesis in mice
2019-12-12
0.90
Involvement of condensin in cellular senescence through gene regulation and compartmental reorganization
2019-12-12
0.90
Maternal vaccination and protective immunity against Zika virus vertical transmission
2019-12-12
0.94
Pan-cancer molecular subtypes revealed by mass-spectrometry-based proteomic characterization of more than 500 human cancers
2019-12-12
1
TRPV1 activity and substance P release are required for corneal cold nociception
2019-12-12
0.96
An intravital window to image the colon in real time
2019-12-11
1
BRCA1 intronic Alu elements drive gene rearrangements and PARP inhibitor resistance
2019-12-11
0.79
DNA methylation directs microRNA biogenesis in mammalian cells
2019-12-11
0.04
Extracellular vesicles from symbiotic vaginal lactobacilli inhibit HIV-1 infection of human tissues
2019-12-11
0.63
Flagellin-elicited adaptive immunity suppresses flagellated microbiota and vaccinates against chronic inflammatory diseases
2019-12-11
0.63
Genetic determinants of the molecular portraits of epithelial cancers
2019-12-11
1
Mutant p53 drives clonal hematopoiesis through modulating epigenetic pathway
2019-12-11
0.98
Normalization governs attentional modulation within human visual cortex
2019-12-11
1
Selective small molecule PARG inhibitor causes replication fork stalling and cancer cell death
2019-12-11
0.97
The autophagy receptor p62/SQST-1 promotes proteostasis and longevity in C. elegans by inducing autophagy
2019-12-11
0.62
Bioinspired design of flexible armor based on chiton scales
2019-12-10
0.92
Deciphering protein evolution and fitness landscapes with latent space models
2019-12-10
1
In vivo pressure gradient heterogeneity increases flow contribution of small diameter vessels in grapevine
2019-12-10
0.63
New insects feeding on dinosaur feathers in mid-Cretaceous amber
2019-12-10
0.04
Sensory innervation in porous endplates by Netrin-1 from osteoclasts mediates PGE2-induced spinal hypersensitivity in mice
2019-12-10
0.80
TRPML1 links lysosomal calcium to autophagosome biogenesis through the activation of the CaMKKβ/VPS34 pathway
2019-12-10
0.04
The epigenomic landscape of transposable elements across normal human development and anatomy
2019-12-10
0.92
Tropical carbon sink accelerated by symbiotic dinitrogen fixation
2019-12-10
0.63
ASCL1 is a MYCN- and LMO1-dependent member of the adrenergic neuroblastoma core regulatory circuitry
2019-12-09
0.63
Emergence of collective oscillations in adaptive cells
2019-12-09
0.17
High-resolution micro-epidemiology of parasite spatial and temporal dynamics in a high malaria transmission setting in Kenya
2019-12-09
0.75
Oxidation and alkylation stresses activate ribosome-quality control
2019-12-09
1
Permeability of membranes in the liquid ordered and liquid disordered phases
2019-12-09
0.86
Solution structure of human myeloid-derived growth factor suggests a conserved function in the endoplasmic reticulum
2019-12-09
0.91
Engineered E. coli Nissle 1917 for the delivery of matrix-tethered therapeutic domains to the gut
2019-12-06
0.92
In silico prediction of high-resolution Hi-C interaction matrices
2019-12-06
1
LinkedSV for detection of mosaic structural variants from linked-read exome and genome sequencing data
2019-12-06
0.80
Mapping lung cancer epithelial-mesenchymal transition states and trajectories with single-cell resolution
2019-12-06
1
Muscleblind acts as a modifier of FUS toxicity by modulating stress granule dynamics and SMN localization
2019-12-06
0.65
Reactive metabolite production is a targetable liability of glycolytic metabolism in lung cancer
2019-12-06
1
Resolving the cause of recurrent Plasmodium vivax malaria probabilistically
2019-12-06
0.27
Stem-cell-ubiquitous genes spatiotemporally coordinate division through regulation of stem-cell-specific gene networks
2019-12-06
1
Structural basis of ligand selectivity and disease mutations in cysteinyl leukotriene receptors
2019-12-06
0.24
The calcium channel subunit αδ-3 organizes synapses via an activity-dependent and autocrine BMP signaling pathway
2019-12-06
1
The visual word form area (VWFA) is part of both language and attention circuitry
2019-12-06
0.67
Conformational pathway provides unique sensitivity to a synaptic mGluR
2019-12-05
0.75
Cryo-EM structure of the human MLL1 core complex bound to the nucleosome
2019-12-05
1
Global urban expansion offsets climate-driven increases in terrestrial net primary productivity
2019-12-05
0.22
Heterogeneity and dynamics of active Kras-induced dysplastic lineages from mouse corpus stomach
2019-12-05
0.97
Infectious stimuli promote malignant B-cell acute lymphoblastic leukemia in the absence of AID
2019-12-05
0.06
LRRK2 kinase activity regulates lysosomal glucocerebrosidase in neurons derived from Parkinson’s disease patients
2019-12-05
1
Predictive impact of rare genomic copy number variations in siblings of individuals with autism spectrum disorders
2019-12-05
0.32
Structural basis of denuded glycan recognition by SPOR domains in bacterial cell division
2019-12-05
0.67
Syngeneic animal models of tobacco-associated oral cancer reveal the activity of in situ anti-CTLA-4
2019-12-05
0.84
CD4 T cell help creates memory CD8 T cells with innate and help-independent recall capacities
2019-12-04
0.04
Cerebral oxygenation during locomotion is modulated by respiration
2019-12-04
0.63
Dynamic and tunable metabolite control for robust minimal-equipment assessment of serum zinc
2019-12-04
1
Epidemic dynamics of respiratory syncytial virus in current and future climates
2019-12-04
1
Gut uropathogen abundance is a risk factor for development of bacteriuria and urinary tract infection
2019-12-04
1
Renewed proliferation in adult mouse cochlea and regeneration of hair cells
2019-12-04
0.74
Resettable skin interfaced microfluidic sweat collection devices with chemesthetic hydration feedback
2019-12-04
0.84
Self-regenerating giant hyaluronan polymer brushes
2019-12-04
1
Synthetic chimeric nucleases function for efficient genome editing
2019-12-04
0.94
The transcriptome mostly consists of independently regulated modules
2019-12-04
0.87
Barrier-to-autointegration factor 1 (Banf1) regulates poly [ADP-ribose] polymerase 1 (PARP1) activity following oxidative DNA damage
2019-12-03
0.09
Estimating heritability and genetic correlations from large health datasets in the absence of genetic data
2019-12-03
0.60
Molecular engineering of organic semiconductors enables noble metal-comparable SERS enhancement and sensitivity
2019-12-03
0.38
Multimodal image registration and connectivity analysis for integration of connectomic data from microscopy to MRI
2019-12-03
1
The coincidence of ecological opportunity with hybridization explains rapid adaptive radiation in Lake Mweru cichlid fishes
2019-12-03
0.04
Using somatic variant richness to mine signals from rare variants in the cancer genome
2019-12-03
1
A cancer rainbow mouse for visualizing the functional genomics of oncogenic clonal expansion
2019-12-02
1
Components of the ribosome biogenesis pathway underlie establishment of telomere length set point in Arabidopsis
2019-12-02
0.55
DNA methylation in AgRP neurons regulates voluntary exercise behavior in mice
2019-12-02
1
Declines in HIV incidence among men and women in a South African population-based cohort
2019-12-02
0.39
General structural features that regulate integrin affinity revealed by atypical αVβ8
2019-12-02
1
Global redox proteome and phosphoproteome analysis reveals redox switch in Akt
2019-12-02
0.04
LRIG1 is a pleiotropic androgen receptor-regulated feedback tumor suppressor in prostate cancer
2019-12-02
0.94
Myc controls a distinct transcriptional program in fetal thymic epithelial cells that determines thymus growth
2019-12-02
0.91
Phylogenomics of 10,575 genomes reveals evolutionary proximity between domains Bacteria and Archaea
2019-12-02
0.75
Seawater softening of suture zones inhibits fracture propagation in Antarctic ice shelves
2019-12-02
0.09
Unveiling how intramolecular stacking modes of covalently linked dimers dictate photoswitching properties
2019-12-02
0.02
92 55.28
1 0.83
78 51.61
153 105.50
74 60.03
108 85.85
81 64.61
213 182.14
156 106.03
284 216.28
1922 1480.98
265 182.56
328 233.82
699 499.53
217 169.33
99 47.48
118 85.79
71 40.81
1084 890.33
Earth & Environmental Sciences 4341 2853.57
Chemistry 7235 5250.77
Physical Sciences 8259 5364.59

1 December 2019 - 30 November 2020

View the connected world of international research collaboration. Visualize collaborations by subject or region.

Collaborations between countries

Percentage of collaboration by Share

Hover over the graph to view the percentage of collaboration.

Top 10 collaborators by Share

  • United States of America (USA)
  1. China (4420.77)
    2106.75
    2314.03
  2. 1144.34
    831.17
  3. Germany (1914.97)
    1082.34
    832.63
  4. Canada (1205.80)
    753.10
    452.71
  5. France (1078.91)
    656.65
    422.26
  6. Japan (974.94)
    598.68
    376.26
  7. Australia (712.66)
    427.56
    285.10
  8. Switzerland (698.47)
    414.10
    284.37
  9. South Korea (697.43)
    420.77
    276.66
  10. Italy (582.81)
    354.79
    228.01

Collaboration is determined by the combined fractional count (Share) of United States of America (USA) and the collaborating country.

Top 10 institutions from United States of America (USA)

Institution Count Share
1. Harvard University 2535 914
2. Stanford University 1694 647.18
3. Massachusetts Institute of Technology (MIT) 1828 528.46
4. National Institutes of Health (NIH) 1085 404.29
5. University of California, Berkeley (UC Berkeley) 1297 395.84
6. University of Michigan (U-M) 1010 391.33
7. Yale University 987 350.79
8. University of California, San Diego (UC San Diego) 1003 342.66
9. Columbia University in the City of New York (CU) 1027 327.89
10. University of California, Los Angeles (UCLA) 1114 327.29

Enhanced profiles

Get your institution here

Return to country/territory outputs