United States of America (USA)

1 December 2019 - 30 November 2020

Subject/journal group: All

The table to the right includes counts of all research outputs for United States of America (USA) published between 1 December 2019 - 30 November 2020 which are tracked by the Nature Index.

Hover over the donut graph to view the FC output for each subject. Below, the same research outputs are grouped by subject. Click on the subject to drill-down into a list of articles organized by journal, and then by title.

Note: Articles may be assigned to more than one subject area.

Count Share
28986 20575.61

Outputs by subject (FC)

Subject Count Share
Life Sciences 12951 9608.83
113 68.86
92 74.32
263 209.84
286 222.26
98 73.98
93 64.78
102 81.37
1 1
290 206.53
119 97.31
70 44.50
1 0.44
72 61.25
98 69.18
88 68.97
789 660.54
139 109.68
370 282.30
123 83.23
A defect in COPI-mediated transport of STING causes immune dysregulation in COPA syndrome
2020-11-02
0.70
A high-affinity antibody against the CSP N-terminal domain lacks Plasmodium falciparum inhibitory activity
2020-11-02
0.31
Blood plasma phosphorylated-tau isoforms track CNS change in Alzheimer’s disease
2020-11-02
1
Constructing and deconstructing GATA2-regulated cell fate programs to establish developmental trajectories
2020-11-02
1
Imaging resident and recruited macrophage contribution to Wallerian degeneration
2020-11-02
0.09
Monocyte-derived macrophages promote breast cancer bone metastasis outgrowth
2020-11-02
0.10
Necroptosis restricts influenza A virus as a stand-alone cell death mechanism
2020-11-02
1
Requirements for cDC2 positioning in blood-exposed regions of the neonatal and adult spleen
2020-11-02
1
Serum HBsAg clearance has minimal impact on CD8+ T cell responses in mouse models of HBV infection
2020-11-02
0.40
β-Catenin induces transcriptional expression of PD-L1 to promote glioblastoma immune evasion
2020-11-02
0.14
AKT-dependent NOTCH3 activation drives tumor progression in a model of mesenchymal colorectal cancer
2020-10-05
0.05
Cancer cell CCR2 orchestrates suppression of the adaptive immune response
2020-10-05
0.93
Cerebral cavernous malformations are driven by ADAMTS5 proteolysis of versican
2020-10-05
0.80
Deciphering and predicting CD4+ T cell immunodominance of influenza virus hemagglutinin
2020-10-05
0.18
Ganglioneuromas are driven by activated AKT and can be therapeutically targeted with mTOR inhibitors
2020-10-05
1
Lipocalin-2 counteracts metabolic dysregulation in obesity and diabetes
2020-10-05
0.73
Liver X receptors are required for thymic resilience and T cell output
2020-10-05
0.87
Mutations in the exocyst component EXOC2 cause severe defects in human brain development
2020-10-05
0.16
Noncanonical STAT3 activity sustains pathogenic Th17 proliferation and cytokine response to antigen
2020-10-05
0.95
Profiling HPV-16–specific T cell responses reveals broad antigen reactivities in oropharyngeal cancer patients
2020-10-05
0.09
Single-cell analysis of germinal-center B cells informs on lymphoma cell of origin and outcome
2020-10-05
1
Multi-omic comparison of Alzheimer’s variants in human ESC–derived microglia reveals convergence at APOE
2020-09-17
1
Molecular imaging of Alzheimer’s disease–related gamma-secretase in mice and nonhuman primates
2020-09-16
1
Anti-human TREM2 induces microglia proliferation and reduces pathology in an Alzheimer’s disease model
2020-09-07
1
Autologous tumor cell vaccine induces antitumor T cell immune responses in patients with mantle cell lymphoma: A phase I/II trial
2020-09-07
0.96
BACH2 drives quiescence and maintenance of resting Treg cells to promote homeostasis and cancer immunosuppression
2020-09-07
0.08
Cbl and Cbl-b control the germinal center reaction by facilitating naive B cell antigen processing
2020-09-07
0.13
Distinct functions of tissue-resident and circulating memory Th2 cells in allergic airway disease
2020-09-07
1
Glutamine depletion regulates Slug to promote EMT and metastasis in pancreatic cancer
2020-09-07
1
Japanese encephalitis virus–primed CD8+ T cells prevent antibody-dependent enhancement of Zika virus pathogenesis
2020-09-07
0.08
Layilin augments integrin activation to promote antitumor immunity
2020-09-07
1
Loss of decay-accelerating factor triggers podocyte injury and glomerulosclerosis
2020-09-07
0.69
Neuronal interleukin-1 receptors mediate pain in chronic inflammatory diseases
2020-09-07
0.12
Poor quality Vβ recombination signal sequences stochastically enforce TCRβ allelic exclusion
2020-09-07
1
SOAT1 promotes mevalonate pathway dependency in pancreatic cancer
2020-09-07
0.98
Targeting leukocidin-mediated immune evasion protects mice from Staphylococcus aureus bacteremia
2020-09-07
1
Accumulation of long-chain fatty acids in the tumor microenvironment drives dysfunction in intrapancreatic CD8+ T cells
2020-08-03
0.75
Acidic fibroblast growth factor underlies microenvironmental regulation of MYC in pancreatic cancer
2020-08-03
1
Distinct fibroblast functional states drive clinical outcomes in ovarian cancer and are regulated by TCF21
2020-08-03
0.09
Intestinal CD8αα IELs derived from two distinct thymic precursors have staggered ontogeny
2020-08-03
1
Mechanosensing through YAP controls T cell activation and metabolism
2020-08-03
1
NK cell receptor NKG2D enforces proinflammatory features and pathogenicity of Th1 and Th17 cells
2020-08-03
0.05
Nicotine promotes brain metastasis by polarizing microglia and suppressing innate immune function
2020-08-03
1
Retrograde migration supplies resident memory T cells to lung-draining LN after influenza infection
2020-08-03
1
Synaptic restoration by cAMP/PKA drives activity-dependent neuroprotection to motoneurons in ALS
2020-08-03
0.08
Targeting CLK3 inhibits the progression of cholangiocarcinoma by reprogramming nucleotide metabolism
2020-08-03
0.09
Tissue-resident memory T cell reactivation by diverse antigen-presenting cells imparts distinct functional responses
2020-08-03
0.92
Type 1 conventional dendritic cells are systemically dysregulated early in pancreatic carcinogenesis
2020-08-03
1
FcRn is a CD32a coreceptor that determines susceptibility to IgG immune complex–driven autoimmunity
2020-07-13
0.59
Antigen-responsive CD4+ T cell clones contribute to the HIV-1 latent reservoir
2020-07-06
1
Blimp-1 is essential for allergen-induced asthma and Th2 cell development in the lung
2020-07-06
1
HSV1 VP1-2 deubiquitinates STING to block type I interferon expression and promote brain infection
2020-07-06
0.06
Hdac3 is an epigenetic inhibitor of the cytotoxicity program in CD8 T cells
2020-07-06
1
Impact of checkpoint blockade on cancer vaccine–activated CD8+ T cell responses
2020-07-06
1
KRAS or BRAF mutations cause hepatic vascular cavernomas treatable with MAP2K–MAPK1 inhibition
2020-07-06
1
NLRC4 inflammasome activation is NLRP3- and phosphorylation-independent during infection and does not protect from melanoma
2020-07-06
1
SIRT1–NOX4 signaling axis regulates cancer cachexia
2020-07-06
1
Dominant-negative mutations in human IL6ST underlie hyper-IgE syndrome
2020-06-01
0.25
Endothelial mTOR maintains hematopoiesis during aging
2020-06-01
1
Hippo/Mst signaling coordinates cellular quiescence with terminal maturation in iNKT cell development and fate decisions
2020-06-01
1
Nicotinamide nucleotide transhydrogenase regulates mitochondrial metabolism in NSCLC through maintenance of Fe-S protein function
2020-06-01
1
PRDM16 suppresses HIF-targeted gene expression in kidney cancer
2020-06-01
1
Single-cell profiling reveals an endothelium-mediated immunomodulatory pathway in the eye choroid
2020-06-01
0.83
A population of proinflammatory T cells coexpresses αβ and γδ T cell receptors in mice and humans
2020-05-04
0.31
Chloride intracellular channel 1 cooperates with potassium channel EAG2 to promote medulloblastoma growth
2020-05-04
0.05
Glioma stem-like cells evade interferon suppression through MBD3/NuRD complex–mediated STAT1 downregulation
2020-05-04
0.08
Homozygous STAT2 gain-of-function mutation by loss of USP18 activity in a patient with type I interferonopathy
2020-05-04
0.63
IL-21 is a broad negative regulator of IgE class switch recombination in mouse and human B cells
2020-05-04
1
Intratumoral accumulation of gut microbiota facilitates CD47-based immunotherapy via STING signaling
2020-05-04
1
NK cell–derived GM-CSF potentiates inflammatory arthritis and is negatively regulated by CIS
2020-05-04
0.11
Physiological expression and function of the MDR1 transporter in cytotoxic T lymphocytes
2020-05-04
1
Somatic SMAD3-activating mutations cause melorheostosis by up-regulating the TGF-β/SMAD pathway
2020-05-04
0.82
Stearoyl-CoA desaturase-1 impairs the reparative properties of macrophages and microglia in the brain
2020-05-04
0.11
Trib1 regulates T cell differentiation during chronic infection by restraining the effector program
2020-05-04
1
USP22 controls iNKT immunity through MED1 suppression of histone H2A monoubiquitination
2020-05-04
0.73
Activation of group 2 innate lymphoid cells alleviates aging-associated cognitive decline
2020-04-06
1
Cell-intrinsic adrenergic signaling controls the adaptive NK cell response to viral infection
2020-04-06
0.71
Essential cell-extrinsic requirement for PDIA6 in lymphoid and myeloid development
2020-04-06
1
Macrophage galactose lectin is critical for Kupffer cells to clear aged platelets
2020-04-06
0.09
Mutation position is an important determinant for predicting cancer neoantigens
2020-04-06
1
Neuronal Epac1 mediates retinal neurodegeneration in mouse models of ocular hypertension
2020-04-06
0.96
Plaque-associated myeloid cells derive from resident microglia in an Alzheimer’s disease model
2020-04-06
0.50
Sequential ubiquitination of NLRP3 by RNF125 and Cbl-b limits inflammasome activation and endotoxemia
2020-04-06
0.85
The colonic macrophage transcription factor RBP-J orchestrates intestinal immunity against bacterial pathogens
2020-04-06
0.17
Tissue-specific pathways extrude activated ILC2s to disseminate type 2 immunity
2020-04-06
1
Transcriptional profiling identifies caspase-1 as a T cell–intrinsic regulator of Th17 differentiation
2020-04-06
1
Innate immune priming in the absence of TAK1 drives RIPK1 kinase activity–independent pyroptosis, apoptosis, necroptosis, and inflammatory disease
2020-03-02
0.90
Absence of GP130 cytokine receptor signaling causes extended Stüve-Wiedemann syndrome
2020-03-02
0.07
Acetate coordinates neutrophil and ILC3 responses against C. difficile through FFAR2
2020-03-02
0.20
Deregulated Notch and Wnt signaling activates early-stage myeloid regeneration pathways in leukemia
2020-03-02
1
Functional interactions between Mi-2β and AP1 complexes control response and recovery from skin barrier disruption
2020-03-02
1
The Toxoplasma gondii virulence factor ROP16 acts in cis and trans, and suppresses T cell responses
2020-03-02
0.88
The transcription factor NFAT5 limits infection-induced type I interferon responses
2020-03-02
0.18
A super enhancer controls expression and chromatin architecture within the MHC class II locus
2020-02-03
1
Activated PI3Kδ breaches multiple B cell tolerance checkpoints and causes autoantibody production
2020-02-03
0.08
B cells are sufficient to prime the dominant CD4+ Tfh response to Plasmodium infection
2020-02-03
1
Downregulation of CFIm25 amplifies dermal fibrosis through alternative polyadenylation
2020-02-03
0.97
Extensive dissemination and intraclonal maturation of HIV Env vaccine-induced B cell responses
2020-02-03
0.39
ILC2s are the predominant source of intestinal ILC-derived IL-10
2020-02-03
0.93
Loss of IL-10 signaling in macrophages limits bacterial killing driven by prostaglandin E2
2020-02-03
0.02
Mechanism of differential Zika and dengue virus neutralization by a public antibody lineage targeting the DIII lateral ridge
2020-02-03
1
Mevalonate metabolism–dependent protein geranylgeranylation regulates thymocyte egress
2020-02-03
0.88
TIPE2 specifies the functional polarization of myeloid-derived suppressor cells during tumorigenesis
2020-02-03
0.36
AP-1 activity induced by co-stimulation is required for chromatin opening during T cell activation
2020-01-06
1
Cell type–specific actions of Bcl11b in early T-lineage and group 2 innate lymphoid cells
2020-01-06
0.39
Collective cancer invasion forms an integrin-dependent radioresistant niche
2020-01-06
0.12
Core 1–derived mucin-type O-glycosylation protects against spontaneous gastritis and gastric cancer
2020-01-06
0.67
Developmental and cellular age direct conversion of CD4+ T cells into RORγ+ or Helios+ colon Treg cells
2020-01-06
1
Disruption of mosGILT in Anopheles gambiae impairs ovarian development and Plasmodium infection
2020-01-06
0.89
Endothelial Cdk5 deficit leads to the development of spontaneous epilepsy through CXCL1/CXCR2-mediated reactive astrogliosis
2020-01-06
0.06
Nutrient mTORC1 signaling underpins regulatory T cell control of immune tolerance
2020-01-06
1
c-Maf regulates the plasticity of group 3 innate lymphoid cells by restraining the type 1 program
2020-01-06
0.75
Human tau pathology transmits glial tau aggregates in the absence of neuronal tau
2019-12-12
1
A homozygous SFTPA1 mutation drives necroptosis of type II alveolar epithelial cells in patients with idiopathic pulmonary fibrosis
2019-12-02
0.11
A novel disorder involving dyshematopoiesis, inflammation, and HLH due to aberrant CDC42 function
2019-12-02
0.22
CXCR6 regulates localization of tissue-resident memory CD8 T cells to the airways
2019-12-02
0.64
Creatine uptake regulates CD8 T cell antitumor immunity
2019-12-02
1
ILC2s mediate systemic innate protection by priming mucus production at distal mucosal sites
2019-12-02
0.33
Intratumoral delivery of RIG-I agonist SLR14 induces robust antitumor responses
2019-12-02
1
Modulation of the fungal mycobiome is regulated by the chitin-binding receptor FIBCD1
2019-12-02
0.49
Platelet-activating factor (PAF) mediates NLRP3-NEK7 inflammasome induction independently of PAFR
2019-12-02
1
Primary prostate cancer educates bone stroma through exosomal pyruvate kinase M2 to promote bone metastasis
2019-12-02
1
Selective inhibition of low-affinity memory CD8+ T cells by corticosteroids
2019-12-02
0.30
416 350.22
180 140.73
162 112.95
477 328.90
99 78.77
72 51.49
109 84.90
2186 1421.72
92 55.28
1 0.83
78 51.61
153 105.50
74 60.03
108 85.85
81 64.61
213 182.14
156 106.03
284 216.28
1922 1480.98
265 182.56
328 233.82
699 499.53
217 169.33
99 47.48
118 85.79
71 40.81
1084 890.33
Earth & Environmental Sciences 4341 2853.57
Chemistry 7235 5250.77
Physical Sciences 8259 5364.59

1 December 2019 - 30 November 2020

View the connected world of international research collaboration. Visualize collaborations by subject or region.

Collaborations between countries

Percentage of collaboration by Share

Hover over the graph to view the percentage of collaboration.

Top 10 collaborators by Share

  • United States of America (USA)
  1. China (4420.77)
    2106.75
    2314.03
  2. 1144.34
    831.17
  3. Germany (1914.97)
    1082.34
    832.63
  4. Canada (1205.80)
    753.10
    452.71
  5. France (1078.91)
    656.65
    422.26
  6. Japan (974.94)
    598.68
    376.26
  7. Australia (712.66)
    427.56
    285.10
  8. Switzerland (698.47)
    414.10
    284.37
  9. South Korea (697.43)
    420.77
    276.66
  10. Italy (582.81)
    354.79
    228.01

Collaboration is determined by the combined fractional count (Share) of United States of America (USA) and the collaborating country.

Top 10 institutions from United States of America (USA)

Institution Count Share
1. Harvard University 2535 914
2. Stanford University 1694 647.18
3. Massachusetts Institute of Technology (MIT) 1828 528.46
4. National Institutes of Health (NIH) 1085 404.29
5. University of California, Berkeley (UC Berkeley) 1297 395.84
6. University of Michigan (U-M) 1010 391.33
7. Yale University 987 350.79
8. University of California, San Diego (UC San Diego) 1003 342.66
9. Columbia University in the City of New York (CU) 1027 327.89
10. University of California, Los Angeles (UCLA) 1114 327.29

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