United States of America (USA)

1 December 2019 - 30 November 2020

Subject/journal group: All

The table to the right includes counts of all research outputs for United States of America (USA) published between 1 December 2019 - 30 November 2020 which are tracked by the Nature Index.

Hover over the donut graph to view the FC output for each subject. Below, the same research outputs are grouped by subject. Click on the subject to drill-down into a list of articles organized by journal, and then by title.

Note: Articles may be assigned to more than one subject area.

Count Share
28986 20575.61

Outputs by subject (FC)

Subject Count Share
Life Sciences 12951 9608.83
113 68.86
92 74.32
263 209.84
286 222.26
98 73.98
93 64.78
102 81.37
1 1
290 206.53
119 97.31
70 44.50
1 0.44
72 61.25
98 69.18
88 68.97
789 660.54
139 109.68
370 282.30
Correction of vasopressin deficit in the lateral septum ameliorates social deficits of mouse autism model
2020-11-24
0.25
Myeloid cell–targeted STAT3 inhibition sensitizes head and neck cancers to radiotherapy and T cell–mediated immunity
2020-11-24
1
BCG vaccination history associates with decreased SARS-CoV-2 seroprevalence across a diverse cohort of health care workers
2020-11-19
1
Extracellular traps released by antimicrobial TH17 cells contribute to host defense
2020-11-19
1
The loss-of-function PCSK9Q152H variant increases ER chaperones GRP78 and GRP94 and protects against liver injury
2020-11-19
0.35
Bone marrow adipogenic lineage precursors promote osteoclastogenesis in bone remodeling and pathologic bone loss
2020-11-18
1
Congenital heart disease risk loci identified by genome-wide association study in European patients
2020-11-17
0.03
Kisspeptin receptor agonist has therapeutic potential for female reproductive disorders
2020-11-16
0.13
Lymphatic drainage from bronchus-associated lymphoid tissue in tolerant lung allografts promotes peripheral tolerance
2020-11-16
1
Deubiquitinase USP7 contributes to the pathogenicity of spinal and bulbar muscular atrophy
2020-11-10
1
Oleic acid restores suppressive defects in tissue-resident FOXP3 Tregs from patients with multiple sclerosis
2020-11-10
0.86
Cholinergic dysfunction in the dorsal striatum promotes habit formation and maladaptive eating
2020-11-09
0.11
Decreased adipose tissue oxygenation associates with insulin resistance in individuals with obesity
2020-11-09
1
Pharmacogenomics of intracellular methotrexate polyglutamates in patients’ leukemia cells in vivo
2020-11-09
1
YIPF5 mutations cause neonatal diabetes and microcephaly through endoplasmic reticulum stress
2020-11-09
0.01
Dynamic single-cell RNA sequencing identifies immunotherapy persister cells following PD-1 blockade
2020-11-05
1
Oxidized CaMKII and O-GlcNAcylation cause increased atrial fibrillation in diabetic mice by distinct mechanisms
2020-11-05
0.95
Mitochondrial dysfunction in inflammatory bowel disease alters intestinal epithelial metabolism of hepatic acylcarnitines
2020-11-03
1
Sustained cellular immune dysregulation in individuals recovering from SARS-CoV-2 infection
2020-10-29
1
Humanized neurofibroma model from induced pluripotent stem cells delineates tumor pathogenesis and developmental origins
2020-10-27
1
Neutrophilic inflammation during lung development disrupts elastin assembly and predisposes adult mice to COPD
2020-10-27
1
Mef2d sustains activation of effector Foxp3+ Tregs during transplant survival and anticancer immunity
2020-10-26
0.91
Galectin-7 downregulation in lesional keratinocytes contributes to enhanced IL-17A signaling and skin pathology in psoriasis
2020-10-23
0.08
Graft-versus-host disease depletes plasmacytoid dendritic cell progenitors to impair tolerance induction
2020-10-22
0.70
Guanosine triphosphate links MYC-dependent metabolic and ribosome programs in small-cell lung cancer
2020-10-20
0.96
Lung megakaryocytes are immune modulatory cells
2020-10-20
0.95
Functional α6β4 acetylcholine receptor expression enables pharmacological testing of nicotinic agonists with analgesic properties
2020-10-19
1
Selective SIRPα blockade reverses tumor T cell exclusion and overcomes cancer immunotherapy resistance
2020-10-19
0.07
Identification of human long noncoding RNAs associated with nonalcoholic fatty liver disease and metabolic homeostasis
2020-10-13
0.67
Landscape of coordinated immune responses to H1N1 challenge in humans
2020-10-12
1
Preventing neuronal edema increases network excitability after traumatic brain injury
2020-10-12
1
Mutant SF3B1 promotes AKT- and NF-κB–driven mammary tumorigenesis
2020-10-08
1
Hypothalamic REV-ERB nuclear receptors control diurnal food intake and leptin sensitivity in diet-induced obese mice
2020-10-06
1
Epigenetic modulator inhibition overcomes temozolomide chemoresistance and antagonizes tumor recurrence of glioblastoma
2020-10-05
0.65
HIV-1 viremia not suppressible by antiretroviral therapy can originate from large T cell clones producing infectious virus
2020-10-05
1
Inhibition of the ATM/Chk2 axis promotes cGAS/STING signaling in ARID1A-deficient tumors
2020-10-05
0.94
Multiomic analysis and immunoprofiling reveal distinct subtypes of human angiosarcoma
2020-10-05
0.07
Orally bioavailable CDK9/2 inhibitor shows mechanism-based therapeutic potential in MYCN-driven neuroblastoma
2020-10-05
0.12
mRNA vaccine–induced neoantigen-specific T cell immunity in patients with gastrointestinal cancer
2020-10-05
0.97
A coagulation defect arising from heterozygous premature termination of tissue factor
2020-10-01
0.75
Antiretroviral therapy does not reduce tuberculosis reactivation in a tuberculosis-HIV coinfection model
2020-10-01
1
Beclin 2 negatively regulates innate immune signaling and tumor development
2020-10-01
0.66
CBFB-MYH11 fusion neoantigen enables T cell recognition and killing of acute myeloid leukemia
2020-10-01
1
Cyclophilin D–dependent oligodendrocyte mitochondrial ion leak contributes to neonatal white matter injury
2020-10-01
1
Decreased lymphatic HIF-2α accentuates lymphatic remodeling in lymphedema
2020-10-01
1
Dysfunction of parvalbumin neurons in the cerebellar nuclei produces an action tremor
2020-10-01
1
Everolimus improves the efficacy of dasatinib in PDGFRα-driven glioma
2020-10-01
1
Graft IL-33 regulates infiltrating macrophages to protect against chronic rejection
2020-10-01
0.94
Haploinsufficiency of immune checkpoint receptor CTLA4 induces a distinct neuroinflammatory disorder
2020-10-01
1
Human NK cell deficiency as a result of biallelic mutations in MCM10
2020-10-01
0.74
IL-17 and immunologically induced senescence regulate response to injury in osteoarthritis
2020-10-01
0.94
Immobilization after injury alters extracellular matrix and stem cell fate
2020-10-01
1
Improved killing of HIV-infected cells using three neutralizing and non-neutralizing antibodies
2020-10-01
1
Inactivation of paracellular cation-selective claudin-2 channels attenuates immune-mediated experimental colitis in mice
2020-10-01
0.90
Kinetics of viral load and antibody response in relation to COVID-19 severity
2020-10-01
0.02
LIN28B promotes the development of neuroendocrine prostate cancer
2020-10-01
0.14
Mapping mania symptoms based on focal brain damage
2020-10-01
0.50
Mutations in the iron-sulfur cluster biogenesis protein HSCB cause congenital sideroblastic anemia
2020-10-01
1
Perforin-deficient CAR T cells recapitulate late-onset inflammatory toxicities observed in patients
2020-10-01
0.95
Prevalence and pathogenicity of autoantibodies in patients with idiopathic CD4 lymphopenia
2020-10-01
1
Protein tyrosine phosphatase nonreceptor type 2 controls colorectal cancer development
2020-10-01
0.05
SIV infection duration largely determines broadening of neutralizing antibody response in macaques
2020-10-01
0.80
Soluble RARRES1 induces podocyte apoptosis to promote glomerular disease progression
2020-10-01
0.75
Targeting tumor-associated macrophages and granulocytic myeloid-derived suppressor cells augments PD-1 blockade in cholangiocarcinoma
2020-10-01
1
Transcriptional frameshifts contribute to protein allergenicity
2020-10-01
0.07
Transcriptome-directed analysis for Mendelian disease diagnosis overcomes limitations of conventional genomic testing
2020-10-01
0.83
p38 Mitogen-activated protein kinase regulates chamber-specific perinatal growth in heart
2020-10-01
0.91
Brain immune cells undergo cGAS/STING-dependent apoptosis during herpes simplex virus type 1 infection to limit type I IFN production
2020-09-29
0.05
Endothelial C3a receptor mediates vascular inflammation and blood-brain barrier permeability during aging
2020-09-29
0.80
MAL2 drives immune evasion in breast cancer by suppressing tumor antigen presentation
2020-09-29
1
Tumor genotype dictates radiosensitization after Atm deletion in primary brainstem glioma models
2020-09-29
1
DNA damage and growth hormone hypersecretion in pituitary somatotroph adenomas
2020-09-28
1
Diagnostic accuracy of three urine lipoarabinomannan tuberculosis assays in HIV-negative outpatients
2020-09-28
0.20
Dominant-negative NFKBIA mutation promotes IL-1β production causing hepatic disease with severe immunodeficiency
2020-09-28
0.01
Stiff stroma increases breast cancer risk by inducing the oncogene ZNF217
2020-09-28
1
X chromosome dosage of histone demethylase KDM5C determines sex differences in adiposity
2020-09-28
0.89
CMV viral load kinetics as surrogate endpoints after allogeneic transplantation
2020-09-24
1
Tobacco smoking induces metabolic reprogramming of renal cell carcinoma
2020-09-24
1
Healthy donor T cell responses to common cold coronaviruses and SARS-CoV-2
2020-09-23
1
Epsins 1 and 2 promote NEMO linear ubiquitination via LUBAC to drive breast cancer development
2020-09-22
1
Herpes simplex encephalitis in a patient with a distinctive form of inherited IFNAR1 deficiency
2020-09-22
0.35
NOTCH-induced rerouting of endosomal trafficking disables regulatory T cells in vasculitis
2020-09-22
1
Apobec1 complementation factor overexpression promotes hepatic steatosis, fibrosis, and hepatocellular cancer
2020-09-17
0.93
Stressed erythrophagocytosis induces immunosuppression during sepsis through heme-mediated STAT1 dysregulation
2020-09-17
1
A protumorigenic secretory pathway activated by p53 deficiency in lung adenocarcinoma
2020-09-15
1
The ABO histo-blood group, endothelial activation, and acute respiratory distress syndrome risk in critical illness
2020-09-15
0.91
Tissue-resident PSGL1loCD4+ T cells promote B cell differentiation and chronic graft-versus-host disease–associated autoimmunity
2020-09-15
0.88
Convalescent plasma anti–SARS-CoV-2 spike protein ectodomain and receptor-binding domain IgG correlate with virus neutralization
2020-09-10
1
BCL11A enhancer–edited hematopoietic stem cells persist in rhesus monkeys without toxicity
2020-09-08
0.96
Favorable outcomes of COVID-19 in recipients of hematopoietic cell transplantation
2020-09-08
1
Germ cell tumors and associated hematologic malignancies evolve from a common shared precursor
2020-09-08
1
Inhibition of IRF5 hyperactivation protects from lupus onset and severity
2020-09-08
1
Maintenance DNA methylation is essential for regulatory T cell development and stability of suppressive function
2020-09-08
1
Sphingosine kinase 2 restricts T cell immunopathology but permits viral persistence
2020-09-08
0.67
Anti–influenza H7 human antibody targets antigenic site in hemagglutinin head domain interface
2020-09-01
1
Auxiliary trafficking subunit GJA1-20k protects connexin-43 from degradation and limits ventricular arrhythmias
2020-09-01
1
Early safety indicators of COVID-19 convalescent plasma in 5000 patients
2020-09-01
1
FGFR4 regulates tumor subtype differentiation in luminal breast cancer and metastatic disease
2020-09-01
0.64
Impaired hypocretin/orexin system alters responses to salient stimuli in obese male mice
2020-09-01
0.86
Krabbe disease successfully treated via monotherapy of intrathecal gene therapy
2020-09-01
1
Long noncoding RNA H19X is a key mediator of TGF-β–driven fibrosis
2020-09-01
0.17
MICAL1 constrains cardiac stress responses and protects against disease by oxidizing CaMKII
2020-09-01
0.90
Neuronal uptake transporters contribute to oxaliplatin neurotoxicity in mice
2020-09-01
0.88
PRICKLE3 linked to ATPase biogenesis manifested Leber’s hereditary optic neuropathy
2020-09-01
0.05
Pancreatic ductal adenocarcinoma progression is restrained by stromal matrix
2020-09-01
0.83
Peripheral host T cells survive hematopoietic stem cell transplantation and promote graft-versus-host disease
2020-09-01
0.76
SARS–CoV-2 infection of the placenta
2020-09-01
1
Tau is not necessary for amyloid-β–induced synaptic and memory impairments
2020-09-01
0.71
p53/microRNA-214/ULK1 axis impairs renal tubular autophagy in diabetic kidney disease
2020-09-01
0.70
β-Glucan–induced reprogramming of human macrophages inhibits NLRP3 inflammasome activation in cryopyrinopathies
2020-09-01
0.11
γ9δ2T cell diversity and the receptor interface with tumor cells
2020-09-01
0.18
Astrocytic neogenin/netrin-1 pathway promotes blood vessel homeostasis and function in mouse cortex
2020-08-27
0.73
Selective pharmacological inhibition of the sodium-dependent phosphate cotransporter NPT2a promotes phosphate excretion
2020-08-27
1
Vaccine targeting SIVmac251 protease cleavage sites protects macaques against vaginal infection
2020-08-27
0.29
dmPFC-vlPAG projection neurons contribute to pain threshold maintenance and antianxiety behaviors
2020-08-25
0.04
Haploidentical mixed chimerism cures autoimmunity in established type 1 diabetic mice
2020-08-20
0.90
Mass cytometry detects H3.3K27M-specific vaccine responses in diffuse midline glioma
2020-08-20
1
The DEL-1/β3 integrin axis promotes regulatory T cell responses during inflammation resolution
2020-08-20
0.44
Urine DNA methylation assay enables early detection and recurrence monitoring for bladder cancer
2020-08-20
0.04
Intestinal proinflammatory macrophages induce a phenotypic switch in interstitial cells of Cajal
2020-08-18
0.06
Boosting NAD level suppresses inflammatory activation of PBMCs in heart failure
2020-08-13
1
Mutation affecting the conserved acidic WNK1 motif causes inherited hyperkalemic hyperchloremic acidosis
2020-08-13
0.10
Truncated stathmin-2 is a marker of TDP-43 pathology in frontotemporal dementia
2020-08-13
0.75
Metabolic effects of air pollution exposure and reversibility
2020-08-11
1
Type 2 diabetes risk gene Dusp8 regulates hypothalamic Jnk signaling and insulin sensitivity
2020-08-11
0.03
Sex, age, and hospitalization drive antibody responses in a COVID-19 convalescent plasma donor population
2020-08-07
1
Complement and tissue factor–enriched neutrophil extracellular traps are key drivers in COVID-19 immunothrombosis
2020-08-06
0.06
Protein phosphatase 2A B55β limits CD8+ T cell lifespan following cytokine withdrawal
2020-08-04
0.27
A CLN6-CLN8 complex recruits lysosomal enzymes at the ER for Golgi transfer
2020-08-03
1
AGER1 downregulation associates with fibrosis in nonalcoholic steatohepatitis and type 2 diabetes
2020-08-03
1
Astrocyte-microglia interaction drives evolving neuromyelitis optica lesion
2020-08-03
0.89
Autoantibodies targeting TRIM72 compromise membrane repair and contribute to inflammatory myopathy
2020-08-03
1
Blocking endothelial apoptosis revascularizes the retina in a model of ischemic retinopathy
2020-08-03
0.13
Complement factor H–deficient mice develop spontaneous hepatic tumors
2020-08-03
0.88
Disease-associated CTNNBL1 mutation impairs somatic hypermutation by decreasing nuclear AID
2020-08-03
0.97
Dysfunction of the ciliary ARMC9/TOGARAM1 protein module causes Joubert syndrome
2020-08-03
0.29
Epithelial-derived gasdermin D mediates nonlytic IL-1β release during experimental colitis
2020-08-03
0.83
Genomic landscape of metastatic breast cancer identifies preferentially dysregulated pathways and targets
2020-08-03
1
Gut microbiome communication with bone marrow regulates susceptibility to amebiasis
2020-08-03
0.81
Impaired angiogenesis and extracellular matrix metabolism in autosomal-dominant hyper-IgE syndrome
2020-08-03
1
Inhibition of DNAJ-HSP70 interaction improves strength in muscular dystrophy
2020-08-03
1
Interacting hepatic PAI-1/tPA gene regulatory pathways influence impaired fibrinolysis severity in obesity
2020-08-03
0.94
Kv1.3 modulates neuroinflammation and neurodegeneration in Parkinson’s disease
2020-08-03
0.96
Lack of Flvcr2 impairs brain angiogenesis without affecting the blood-brain barrier
2020-08-03
0.75
Long-range cis-regulatory elements controlling GDF6 expression are essential for ear development
2020-08-03
0.62
Lymph node fibroblastic reticular cells deposit fibrosis-associated collagen following organ transplantation
2020-08-03
0.89
MKRN3 inhibits the reproductive axis through actions in kisspeptin-expressing neurons
2020-08-03
0.93
Maternal diesel particle exposure promotes offspring asthma through NK cell–derived granzyme B
2020-08-03
0.86
Microglia modulation by TGF-β1 protects cones in mouse models of retinal degeneration
2020-08-03
1
Noggin regulates foregut progenitor cell programming and mis-expression leads to esophageal atresia
2020-08-03
1
Nonalcoholic fatty liver disease in CLOCK mutant mice
2020-08-03
1
Posttranslational modifications define course of prion strain adaptation and disease phenotype
2020-08-03
1
Rathke’s cleft-like cysts arise from Isl1 deletion in murine pituitary progenitors
2020-08-03
0.43
Residual endotoxin induces primary graft dysfunction through ischemia-reperfusion-primed alveolar macrophages
2020-08-03
1
Selective role of Nck1 in atherogenic inflammation and plaque formation
2020-08-03
1
Targeting the innate immunoreceptor RIG-I overcomes melanoma-intrinsic resistance to T cell immunotherapy
2020-08-03
0.14
Taste-related reward is associated with weight loss following bariatric surgery
2020-08-03
0.88
The landscape of RNA polymerase II–associated chromatin interactions in prostate cancer
2020-08-03
0.65
Complement activation on endothelium initiates antibody-mediated acute lung injury
2020-07-30
1
DCAF1 regulates Treg senescence via the ROS axis during immunological aging
2020-07-30
0.92
Multisystem inflammatory syndrome in children and COVID-19 are distinct presentations of SARS–CoV-2
2020-07-30
1
Distinct clinical and immunological features of SARS–CoV-2–induced multisystem inflammatory syndrome in children
2020-07-23
1
ERG orchestrates chromatin interactions to drive prostate cell fate reprogramming
2020-07-23
0.18
Caspase-11–mediated enteric neuronal pyroptosis underlies Western diet–induced colonic dysmotility
2020-07-01
0.79
Ecto-NTPDase CD39 is a negative checkpoint that inhibits follicular helper cell generation
2020-07-01
1
Human CRY1 variants associate with attention deficit/hyperactivity disorder
2020-07-01
0.19
PD-1 blockade inhibits osteoclast formation and murine bone cancer pain
2020-07-01
1
Transplantation tolerance modifies donor-specific B cell fate to suppress de novo alloreactive B cells
2020-07-01
1
12(S)-HETE mediates diabetes-induced endothelial dysfunction by activating intracellular endothelial cell TRPV1
2020-06-25
0.10
Filgotinib suppresses HIV-1–driven gene transcription by inhibiting HIV-1 splicing and T cell activation
2020-06-23
1
TPL2 enforces RAS-induced inflammatory signaling and is activated by point mutations
2020-06-23
0.97
Histone methyltransferase MLL4 controls myofiber identity and muscle performance through MEF2 interaction
2020-06-16
0.10
Impact of TREM2R47H variant on tau pathology–induced gliosis and neurodegeneration
2020-06-16
0.83
Melanocortin-4 receptor antagonist TCMCB07 ameliorates cancer- and chronic kidney disease–associated cachexia
2020-06-16
1
BET bromodomain inhibition attenuates cardiac phenotype in myocyte-specific lamin A/C–deficient mice
2020-06-02
1
Bruton’s tyrosine kinase inhibition effectively protects against human IgE-mediated anaphylaxis
2020-06-02
1
FTY720 reactivates cryptococcal granulomas in mice through S1P receptor 3 on macrophages
2020-06-02
0.88
Genomic and epigenomic EBF1 alterations modulate TERT expression in gastric cancer
2020-06-01
0.09
KLK6 expression in skin induces PAR1-mediated psoriasiform dermatitis and inflammatory joint disease
2020-06-01
1
Loss of the Fanconi anemia–associated protein NIPA causes bone marrow failure
2020-06-01
0.03
Myofibroblast contraction is essential for generating and regenerating the gas-exchange surface
2020-06-01
0.80
Neutralizing antibody VRC01 failed to select for HIV-1 mutations upon viral rebound
2020-06-01
0.75
Parkin ubiquitinates phosphoglycerate dehydrogenase to suppress serine synthesis and tumor progression
2020-06-01
1
RNA interference therapeutics targeting angiotensinogen ameliorate preeclamptic phenotype in rodent models
2020-06-01
0.36
Taxane resistance in prostate cancer is mediated by decreased drug-target engagement
2020-06-01
0.94
Upregulation of Rubicon promotes autosis during myocardial ischemia/reperfusion injury
2020-06-01
1
New York City COVID-19 resident physician exposure during exponential phase of pandemic
2020-05-28
1
Human CD83-targeted chimeric antigen receptor T cells prevent and treat graft-versus-host disease
2020-05-21
1
Chemotherapy-induced S100A10 recruits KDM6A to facilitate OCT4-mediated breast cancer stemness
2020-05-19
1
Bacterial CagA protein compromises tumor suppressor mechanisms in gastric epithelial cells
2020-05-01
1
Fetal alcohol spectrum disorder predisposes to metabolic abnormalities in adulthood
2020-05-01
1
Mature myelin maintenance requires Qki to coactivate PPARβ-RXRα–mediated lipid metabolism
2020-05-01
0.79
Myeloid-specific Asxl2 deletion limits diet-induced obesity by regulating energy expenditure
2020-05-01
1
Parental metabolic syndrome epigenetically reprograms offspring hepatic lipid metabolism in mice
2020-05-01
0.56
Pathogenesis of peritumoral hyperexcitability in an immunocompetent CRISPR-based glioblastoma model
2020-05-01
1
Retrograde nerve growth factor signaling abnormalities in familial dysautonomia
2020-05-01
1
Striatal Kir2 K+ channel inhibition mediates the antidyskinetic effects of amantadine
2020-05-01
1
Transcriptional and cytopathological hallmarks of FSHD in chronic DUX4-expressing mice
2020-05-01
0.94
Targeting glutamine metabolism enhances tumor-specific immunity by modulating suppressive myeloid cells
2020-04-23
0.90
HDAC inhibitors elicit metabolic reprogramming by targeting super-enhancers in glioblastoma models
2020-04-21
0.89
HuR/ELAVL1 drives malignant peripheral nerve sheath tumor growth and metastasis
2020-04-21
0.11
IL-1β suppression of VE-cadherin transcription underlies sepsis-induced inflammatory lung injury
2020-04-16
0.93
Macrophages use a bet-hedging strategy for antimicrobial activity in phagolysosomal acidification
2020-04-16
1
Proinflammatory P2Y14 receptor inhibition protects against ischemic acute kidney injury in mice
2020-04-14
1
Exebacase for patients with Staphylococcus aureus bloodstream infection and endocarditis
2020-04-09
1
T follicular regulatory cells and IL-10 promote food antigen–specific IgE
2020-04-07
1
An endocannabinoid-regulated basolateral amygdala–nucleus accumbens circuit modulates sociability
2020-04-01
1
Angiopoietin-2 blockade ameliorates autoimmune neuroinflammation by inhibiting leukocyte recruitment into the CNS
2020-04-01
0.07
Bruton tyrosine kinase deficiency augments NLRP3 inflammasome activation and causes IL-1β–mediated colitis
2020-04-01
1
Capsular glycan recognition provides antibody-mediated immunity against tuberculosis
2020-04-01
0.82
Circulating tumor DNA profile recognizes transformation to castration-resistant neuroendocrine prostate cancer
2020-04-01
0.59
Claudin-2 deficiency associates with hypercalciuria in mice and human kidney stone disease
2020-04-01
0.50
Cystic fibrosis transmembrane conductance regulator dysfunction in platelets drives lung hyperinflammation
2020-04-01
1
Epithelial splicing regulatory protein 2–mediated alternative splicing reprograms hepatocytes in severe alcoholic hepatitis
2020-04-01
0.95
Genome-wide plasma DNA methylation features of metastatic prostate cancer
2020-04-01
0.03
Gut epithelial TSC1/mTOR controls RIPK3-dependent necroptosis in intestinal inflammation and cancer
2020-04-01
0.16
HIV persists throughout deep tissues with repopulation from multiple anatomical sources
2020-04-01
0.70
HPV16 drives cancer immune escape via NLRX1-mediated degradation of STING
2020-04-01
0.82
High residual C-peptide likely contributes to glycemic control in type 1 diabetes
2020-04-01
1
Inhibiting the coregulator CoREST impairs Foxp3+ Treg function and promotes antitumor immunity
2020-04-01
0.90
Leptin mediates postprandial increases in body temperature through hypothalamus–adrenal medulla–adipose tissue crosstalk
2020-04-01
1
Neogenin neutralization prevents photoreceptor loss in inherited retinal degeneration
2020-04-01
0.10
Pancreatic triglyceride lipase mediates lipotoxic systemic inflammation
2020-04-01
1
Parathyroid hormone–dependent bone formation requires butyrate production by intestinal microbiota
2020-04-01
1
Prevention of connexin-43 remodeling protects against Duchenne muscular dystrophy cardiomyopathy
2020-04-01
1
Profilin 1 delivery tunes cytoskeletal dynamics toward CNS axon regeneration
2020-04-01
0.07
Protein arginine methyltransferase 5 promotes cholesterol biosynthesis–mediated Th17 responses and autoimmunity
2020-04-01
1
Small molecule JQ1 promotes prostate cancer invasion via BET-independent inactivation of FOXA1
2020-04-01
1
Steroid resistance in Diamond Blackfan anemia associates with p57Kip2 dysregulation in erythroid progenitors
2020-04-01
0.83
Suppression of the SLC7A11/glutathione axis causes synthetic lethality in KRAS-mutant lung adenocarcinoma
2020-04-01
0.13
TYK2 inhibition reduces type 3 immunity and modifies disease progression in murine spondyloarthritis
2020-04-01
0.27
The Mir181ab1 cluster promotes KRAS-driven oncogenesis and progression in lung and pancreas
2020-04-01
0.50
Transcription factor c-Maf is a checkpoint that programs macrophages in lung cancer
2020-04-01
0.90
Type I interferon response drives neuroinflammation and synapse loss in Alzheimer disease
2020-04-01
1
Visceral adipose NLRP3 impairs cognition in obesity via IL-1R1 on CX3CR1+ cells
2020-04-01
1
Serine-threonine kinase ROCK2 regulates germinal center B cell positioning and cholesterol biosynthesis
2020-03-31
1
Brain-specific repression of AMPKα1 alleviates pathophysiology in Alzheimer’s model mice
2020-03-26
1
B cell–intrinsic TLR9 expression is protective in murine lupus
2020-03-19
1
Complement-activated interferon-γ–primed human endothelium transpresents interleukin-15 to CD8+ T cells
2020-03-19
0.93
Free fatty acid processing diverges in human pathologic insulin resistance conditions
2020-03-19
1
Influence of adiposity, insulin resistance, and intrahepatic triglyceride content on insulin kinetics
2020-03-19
1
Longitudinal study reveals HIV-1–infected CD4+ T cell dynamics during long-term antiretroviral therapy
2020-03-19
1
Oncogene-independent BCR-like signaling adaptation confers drug resistance in Ph-like ALL
2020-03-19
1
Semaphorin 3F signaling actively retains neutrophils at sites of inflammation
2020-03-19
0.02
Sensory nerves regulate mesenchymal stromal cell lineage commitment by tuning sympathetic tones
2020-03-19
0.80
Atypical cadherin FAT4 orchestrates lymphatic endothelial cell polarity in response to flow
2020-03-17
0.19
Bile acid metabolism is altered in multiple sclerosis and supplementation ameliorates neuroinflammation
2020-03-17
1
Melatonin inhibits cytosolic mitochondrial DNA–induced neuroinflammatory signaling in accelerated aging and neurodegeneration
2020-03-17
1
Norrin mediates tumor-promoting and -suppressive effects in glioblastoma via Notch and Wnt
2020-03-17
0.04
OX40+ plasmacytoid dendritic cells in the tumor microenvironment promote antitumor immunity
2020-03-17
1
Sel1L-Hrd1 ER-associated degradation maintains β cell identity via TGF-β signaling
2020-03-17
0.84
Diminished hepatic IFN response following HCV clearance triggers HBV reactivation in coinfection
2020-03-12
0.31
Inherited human IFN-γ deficiency underlies mycobacterial disease
2020-03-12
0.18
Post-sepsis immunosuppression depends on NKT cell regulation of mTOR/IFN-γ in NK cells
2020-03-10
0.88
Minimal PD-1 expression in mouse and human NK cells under diverse conditions
2020-03-05
1
S100A8/A9 regulates CD11b expression and neutrophil recruitment during chronic tuberculosis
2020-03-05
0.55
SIRT2 protects peripheral neurons from cisplatin-induced injury by enhancing nucleotide excision repair
2020-03-05
1
Ventromedial hypothalamic nucleus neuronal subset regulates blood glucose independently of insulin
2020-03-05
1
DNA hypermethylation during tuberculosis dampens host immune responsiveness
2020-03-03
0.59
Enasidenib drives human erythroid differentiation independently of isocitrate dehydrogenase 2
2020-03-03
1
PIK3Cδ expression by fibroblasts promotes triple-negative breast cancer progression
2020-03-03
0.19
PLA2G1B is involved in CD4 anergy and CD4 lymphopenia in HIV-infected patients
2020-03-03
0.08
Tissue-resident T cell–derived cytokines eliminate herpes simplex virus-2–infected cells
2020-03-03
1
A conserved intratumoral regulatory T cell signature identifies 4-1BB as a pan-cancer target
2020-03-02
1
Antiangiogenic immunotherapy suppresses desmoplastic and chemoresistant intestinal tumors in mice
2020-03-02
0.05
CD73 immune checkpoint defines regulatory NK cells within the tumor microenvironment
2020-03-02
0.23
Chikungunya virus replication in skeletal muscle cells is required for disease development
2020-03-02
1
Chronic mTOR activation induces a degradative smooth muscle cell phenotype
2020-03-02
0.98
GABA interneurons are the cellular trigger for ketamine’s rapid antidepressant actions
2020-03-02
1
Glycerol-3-phosphate is a FGF23 regulator derived from the injured kidney
2020-03-02
1
Graft-versus-host disease of the CNS is mediated by TNF upregulation in microglia
2020-03-02
0.05
Inactivation of endothelial ZEB1 impedes tumor progression and sensitizes tumors to conventional therapies
2020-03-02
0.08
Linear ubiquitin assembly complex regulates lung epithelial–driven responses during influenza infection
2020-03-02
0.90
Lysine acetyltransferase 8 is involved in cerebral development and syndromic intellectual disability
2020-03-02
0.35
Muscle-specific SMN reduction reveals motor neuron–independent disease in spinal muscular atrophy models
2020-03-02
1
Myalgic encephalomyelitis/chronic fatigue syndrome patients exhibit altered T cell metabolism and cytokine associations
2020-03-02
1
Oral immunotherapy tolerizes mice to enzyme replacement therapy for Morquio A syndrome
2020-03-02
0.86
Prion protein glycans reduce intracerebral fibril formation and spongiosis in prion disease
2020-03-02
0.73
Shortened TDP43 isoforms upregulated by neuronal hyperactivity drive TDP43 pathology in ALS
2020-03-02
0.55
Salt-inducible kinase 1 maintains HDAC7 stability to promote pathologic cardiac remodeling
2020-02-27
1
Hepatic Slug epigenetically promotes liver lipogenesis, fatty liver disease, and type 2 diabetes
2020-02-25
0.94
Muscle-derived interleukin 6 increases exercise capacity by signaling in osteoblasts
2020-02-20
0.52
Single residue in CD28-costimulated CAR-T cells limits long-term persistence and antitumor durability
2020-02-18
0.94
BCL-2 antagonism sensitizes cytotoxic T cell–resistant HIV reservoirs to elimination ex vivo
2020-02-06
0.91
Epigenetic driver mutations in ARID1A shape cancer immune phenotype and immunotherapy
2020-02-06
0.96
Exosomes mediate sensory hair cell protection in the inner ear
2020-02-06
0.92
Hepatic CEACAM1 expression indicates donor liver quality and prevents early transplantation injury
2020-02-06
1
A tumor-intrinsic PD-L1/NLRP3 inflammasome signaling pathway drives resistance to anti–PD-1 immunotherapy
2020-02-04
1
Plasmacytoid dendritic cells sense HIV replication before detectable viremia following treatment interruption
2020-02-04
0.61
The lymph node stromal laminin α5 shapes alloimmunity
2020-02-04
1
Antigen-loaded monocyte administration induces potent therapeutic antitumor T cell responses
2020-02-03
1
CD19-targeting CAR T cell immunotherapy outcomes correlate with genomic modification by vector integration
2020-02-03
1
Correcting Smad1/5/8, mTOR, and VEGFR2 treats pathology in hereditary hemorrhagic telangiectasia models
2020-02-03
1
Deep learning predicts function of live retinal pigment epithelium from quantitative microscopy
2020-02-03
1
Disrupted ER membrane protein complex–mediated topogenesis drives congenital neural crest defects
2020-02-03
1
Effects of maternal iron status on placental and fetal iron homeostasis
2020-02-03
0.89
EphA4/Tie2 crosstalk regulates leptomeningeal collateral remodeling following ischemic stroke
2020-02-03
1
GRK2 suppresses lymphomagenesis by inhibiting the MALT1 proto-oncoprotein
2020-02-03
0.78
Glucocorticoids paradoxically facilitate steroid resistance in T cell acute lymphoblastic leukemias and thymocytes
2020-02-03
1
H3K27me3-mediated PGC1α gene silencing promotes melanoma invasion through WNT5A and YAP
2020-02-03
1
Human autologous iPSC–derived dopaminergic progenitors restore motor function in Parkinson’s disease models
2020-02-03
0.97
Immune exclusion by naturally acquired secretory IgA against pneumococcal pilus-1
2020-02-03
1
In vivo delivery of synthetic DNA–encoded antibodies induces broad HIV-1–neutralizing activity
2020-02-03
1
KBTBD13 is an actin-binding protein that modulates muscle kinetics
2020-02-03
0.24
Menin inhibitor MI-3454 induces remission in MLL1-rearranged and NPM1-mutated models of leukemia
2020-02-03
1
Notch inhibition overcomes resistance to tyrosine kinase inhibitors in EGFR-driven lung adenocarcinoma
2020-02-03
0.08
SDR9C7 catalyzes critical dehydrogenation of acylceramides for skin barrier formation
2020-02-03
0.16
SIV-specific CD8+ T cells are clonotypically distinct across lymphoid and mucosal tissues
2020-02-03
0.81
Selective induction of antibody effector functional responses using MF59-adjuvanted vaccination
2020-02-03
1
Severe fever with thrombocytopenia syndrome virus targets B cells in lethal human infections
2020-02-03
0.02
TTK inhibition radiosensitizes basal-like breast cancer through impaired homologous recombination
2020-02-03
1
Targetable cellular signaling events mediate vascular pathology in vascular Ehlers-Danlos syndrome
2020-02-03
0.89
The glucocorticoid receptor–FKBP51 complex contributes to fear conditioning and posttraumatic stress disorder
2020-02-03
0.07
Marked and rapid effects of pharmacological HIF-2α antagonism on hypoxic ventilatory control
2020-01-30
0.06
TRPV4 channel opening mediates pressure-induced pancreatitis initiated by Piezo1 activation
2020-01-30
1
Cytotoxic CD4+ T lymphocytes may induce endothelial cell apoptosis in systemic sclerosis
2020-01-28
0.83
IL-17–producing γδ T cells protect against Clostridium difficile infection
2020-01-28
1
Phase I trial of donor-derived modified immune cell infusion in kidney transplantation
2020-01-28
0.03
TGF-β–induced epigenetic deregulation of SOCS3 facilitates STAT3 signaling to promote fibrosis
2020-01-28
0.07
Chronic mirabegron treatment increases human brown fat, HDL cholesterol, and insulin sensitivity
2020-01-21
1
Donor glucose-6-phosphate dehydrogenase deficiency decreases blood quality for transfusion
2020-01-21
0.95
The β3-adrenergic receptor agonist mirabegron improves glucose homeostasis in obese humans
2020-01-21
1
Live attenuated pertussis vaccine BPZE1 induces a broad antibody response in humans
2020-01-16
0.21
A Clostridia-rich microbiota enhances bile acid excretion in diarrhea-predominant irritable bowel syndrome
2020-01-02
0.01
Autoreactive CD8+ T cell exhaustion distinguishes subjects with slow type 1 diabetes progression
2020-01-02
1
BubR1 allelic effects drive phenotypic heterogeneity in mosaic-variegated aneuploidy progeria syndrome
2020-01-02
0.82
Chemogenetic activation of adrenocortical Gq signaling causes hyperaldosteronism and disrupts functional zonation
2020-01-02
1
Chronic myeloid leukemia stem cells require cell-autonomous pleiotrophin signaling
2020-01-02
1
Cross-dressed dendritic cells sustain effector T cell responses in islet and kidney allografts
2020-01-02
0.89
Defective glycosylation and multisystem abnormalities characterize the primary immunodeficiency XMEN disease
2020-01-02
0.82
Deregulating MYC in a model of HER2+ breast cancer mimics human intertumoral heterogeneity
2020-01-02
1
Differential skewing of donor-unrestricted and γδ T cell repertoires in tuberculosis-infected human lungs
2020-01-02
0.13
Epithelial membrane protein 2 governs transepithelial migration of neutrophils into the airspace
2020-01-02
0.94
Epitope-specific airway-resident CD4+ T cell dynamics during experimental human RSV infection
2020-01-02
0.11
Gabapentinoid treatment promotes corticospinal plasticity and regeneration following murine spinal cord injury
2020-01-02
1
Gut microbiota modulate dendritic cell antigen presentation and radiotherapy-induced antitumor immune response
2020-01-02
1
Increased expression of anion transporter SLC26A9 delays diabetes onset in cystic fibrosis
2020-01-02
1
Low- and high-thermogenic brown adipocyte subpopulations coexist in murine adipose tissue
2020-01-02
0.95
Myelin-specific CD8+ T cells exacerbate brain inflammation in CNS autoimmunity
2020-01-02
1
Norepinephrine metabolite DOPEGAL activates AEP and pathological Tau aggregation in locus coeruleus
2020-01-02
0.90
Quadrivalent VesiculoVax vaccine protects nonhuman primates from viral-induced hemorrhagic fever and death
2020-01-02
0.95
Relief of tumor hypoxia unleashes the tumoricidal potential of neutrophils
2020-01-02
1
SSBP1 mutations cause mtDNA depletion underlying a complex optic atrophy disorder
2020-01-02
0.25
Smooth muscle cell–specific fibronectin-EDA mediates phenotypic switching and neointimal hyperplasia
2020-01-02
1
Targeting tumor-intrinsic hexosamine biosynthesis sensitizes pancreatic cancer to anti-PD1 therapy
2020-01-02
1
Trypsin activity governs increased susceptibility to pancreatitis in mice expressing human PRSS1R122H
2020-01-02
1
Distinct interferon signatures and cytokine patterns define additional systemic autoinflammatory diseases
2019-12-24
0.67
CD8+ T cells target cerebrovasculature in children with cerebral malaria
2019-12-10
0.92
DGCR8 microprocessor defect characterizes familial multinodular goiter with schwannomatosis
2019-12-05
0.06
Insulin resistance drives hepatic de novo lipogenesis in nonalcoholic fatty liver disease
2019-12-05
1
Oral N-acetylcysteine improves cone function in retinitis pigmentosa patients in phase I trial
2019-12-05
1
A-to-I–edited miRNA-379-5p inhibits cancer cell proliferation through CD97-induced apoptosis
2019-12-02
0.96
Chimeric antigen receptor–induced BCL11B suppression propagates NK-like cell development
2019-12-02
0.18
Dermal adipose tissue has high plasticity and undergoes reversible dedifferentiation in mice
2019-12-02
0.96
Expression of mitochondrial membrane–linked SAB determines severity of sex-dependent acute liver injury
2019-12-02
0.93
FOXM1 drives proximal tubule proliferation during repair from acute ischemic kidney injury
2019-12-02
0.95
Fracture repair requires TrkA signaling by skeletal sensory nerves
2019-12-02
1
Galectin-1–driven T cell exclusion in the tumor endothelium promotes immunotherapy resistance
2019-12-02
1
Haptoglobin administration into the subarachnoid space prevents hemoglobin-induced cerebral vasospasm
2019-12-02
0.18
Hedgehog signaling promotes tumor-associated macrophage polarization to suppress intratumoral CD8+ T cell recruitment
2019-12-02
1
Hemodynamic regulation of perivalvular endothelial gene expression prevents deep venous thrombosis
2019-12-02
1
High-fat diet exacerbates SIV pathogenesis and accelerates disease progression
2019-12-02
0.98
Maresin 1 activates LGR6 receptor promoting phagocyte immunoresolvent functions
2019-12-02
1
Mechanisms of reactivation of latent tuberculosis infection due to SIV coinfection
2019-12-02
1
Myeloid loss of Beclin 1 promotes PD-L1hi precursor B cell lymphoma development
2019-12-02
0.96
P2Y6 signaling in alveolar macrophages prevents leukotriene-dependent type 2 allergic lung inflammation
2019-12-02
0.82
SHP2 inhibition reduces leukemogenesis in models of combined genetic and epigenetic mutations
2019-12-02
1
Salt-inducible kinases dictate parathyroid hormone 1 receptor action in bone development and remodeling
2019-12-02
0.90
Slowing ribosome velocity restores folding and function of mutant CFTR
2019-12-02
0.73
Suppressing miR-21 activity in tumor-associated macrophages promotes an antitumor immune response
2019-12-02
1
123 83.23
416 350.22
180 140.73
162 112.95
477 328.90
99 78.77
72 51.49
109 84.90
2186 1421.72
92 55.28
1 0.83
78 51.61
153 105.50
74 60.03
108 85.85
81 64.61
213 182.14
156 106.03
284 216.28
1922 1480.98
265 182.56
328 233.82
699 499.53
217 169.33
99 47.48
118 85.79
71 40.81
1084 890.33
Earth & Environmental Sciences 4341 2853.57
Chemistry 7235 5250.77
Physical Sciences 8259 5364.59

1 December 2019 - 30 November 2020

View the connected world of international research collaboration. Visualize collaborations by subject or region.

Collaborations between countries

Percentage of collaboration by Share

Hover over the graph to view the percentage of collaboration.

Top 10 collaborators by Share

  • United States of America (USA)
  1. China (4420.77)
    2106.75
    2314.03
  2. 1144.34
    831.17
  3. Germany (1914.97)
    1082.34
    832.63
  4. Canada (1205.80)
    753.10
    452.71
  5. France (1078.91)
    656.65
    422.26
  6. Japan (974.94)
    598.68
    376.26
  7. Australia (712.66)
    427.56
    285.10
  8. Switzerland (698.47)
    414.10
    284.37
  9. South Korea (697.43)
    420.77
    276.66
  10. Italy (582.81)
    354.79
    228.01

Collaboration is determined by the combined fractional count (Share) of United States of America (USA) and the collaborating country.

Top 10 institutions from United States of America (USA)

Institution Count Share
1. Harvard University 2535 914
2. Stanford University 1694 647.18
3. Massachusetts Institute of Technology (MIT) 1828 528.46
4. National Institutes of Health (NIH) 1085 404.29
5. University of California, Berkeley (UC Berkeley) 1297 395.84
6. University of Michigan (U-M) 1010 391.33
7. Yale University 987 350.79
8. University of California, San Diego (UC San Diego) 1003 342.66
9. Columbia University in the City of New York (CU) 1027 327.89
10. University of California, Los Angeles (UCLA) 1114 327.29

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