United States of America (USA)

1 December 2019 - 30 November 2020

Subject/journal group: All

The table to the right includes counts of all research outputs for United States of America (USA) published between 1 December 2019 - 30 November 2020 which are tracked by the Nature Index.

Hover over the donut graph to view the FC output for each subject. Below, the same research outputs are grouped by subject. Click on the subject to drill-down into a list of articles organized by journal, and then by title.

Note: Articles may be assigned to more than one subject area.

Count Share
28986 20575.61

Outputs by subject (FC)

Subject Count Share
Life Sciences 12951 9608.83
113 68.86
92 74.32
263 209.84
A Circle RNA Regulatory Axis Promotes Lung Squamous Metastasis via CDR1-Mediated Regulation of Golgi Trafficking
2020-11-15
1
CD122-Selective IL2 Complexes Reduce Immunosuppression, Promote Treg Fragility, and Sensitize Tumor Response to PD-L1 Blockade
2020-11-15
0.86
FGFR1 Is Critical for RBL2 Loss–Driven Tumor Development and Requires PLCG1 Activation for Continued Growth of Small Cell Lung Cancer
2020-11-15
0.90
Field Carcinogenesis in Cancer Evolution: What the Cell Is Going On?
2020-11-15
1
Generalized Additive Mixed Modeling of Longitudinal Tumor Growth Reduces Bias and Improves Decision Making in Translational Oncology
2020-11-15
0.67
Glutamate Is a Noninvasive Metabolic Biomarker of IDH1-Mutant Glioma Response to Temozolomide Treatment
2020-11-15
1
Hypoxia Alters the Response to Anti-EGFR Therapy by Regulating EGFR Expression and Downstream Signaling in a DNA Methylation–Specific and HIF-Dependent Manner
2020-11-15
1
Integrating Mathematical Modeling with High-Throughput Imaging Explains How Polyploid Populations Behave in Nutrient-Sparse Environments
2020-11-15
1
KRAS Controls Pancreatic Cancer Cell Lipid Metabolism and Invasive Potential through the Lipase HSL
2020-11-15
1
Local Targeting of NAD+ Salvage Pathway Alters the Immune Tumor Microenvironment and Enhances Checkpoint Immunotherapy in Glioblastoma
2020-11-15
1
Modeling Resistance and Recurrence Patterns of Combined Targeted–Chemoradiotherapy Predicts Benefit of Shorter Induction Period
2020-11-15
1
Morphology-Predicted Large-Scale Transition Number in Circulating Tumor Cells Identifies a Chromosomal Instability Biomarker Associated with Poor Outcome in Castration-Resistant Prostate Cancer
2020-11-15
1
Postdiagnostic Fruit and Vegetable Consumption and Breast Cancer Survival: Prospective Analyses in the Nurses' Health Studies
2020-11-15
1
Protein Arginine Methyltransferase 5 Promotes pICln-Dependent Androgen Receptor Transcription in Castration-Resistant Prostate Cancer
2020-11-15
1
Specific Mechanisms of Chromosomal Instability Indicate Therapeutic Sensitivities in High-Grade Serous Ovarian Carcinoma
2020-11-15
0.05
5-Fluorouracil Enhances the Antitumor Activity of the Glutaminase Inhibitor CB-839 against PIK3CA-Mutant Colorectal Cancers
2020-11-01
1
A DNA Hypomethylating Drug Alters the Tumor Microenvironment and Improves the Effectiveness of Immune Checkpoint Inhibitors in a Mouse Model of Pancreatic Cancer
2020-11-01
1
A Deep Learning Framework Identifies Pathogenic Noncoding Somatic Mutations from Personal Prostate Cancer Genomes
2020-11-01
1
Allosteric SHP2 Inhibitor, IACS-13909, Overcomes EGFR-Dependent and EGFR-Independent Resistance Mechanisms toward Osimertinib
2020-11-01
1
Breast Cancer Cell Detection and Characterization from Breast Milk–Derived Cells
2020-11-01
1
CRISPR/Cas9-Mediated Point Mutation in Nkx3.1 Prolongs Protein Half-Life and Reverses Effects Nkx3.1 Allelic Loss
2020-11-01
1
Cdkn2a Loss in a Model of Neurofibroma Demonstrates Stepwise Tumor Progression to Atypical Neurofibroma and MPNST
2020-11-01
1
ERG-Mediated Coregulator Complex Formation Maintains Androgen Receptor Signaling in Prostate Cancer
2020-11-01
1
EZH2 Regulates Pancreatic Cancer Subtype Identity and Tumor Progression via Transcriptional Repression of GATA6
2020-11-01
0.05
Epigenetic Control of Cdkn2a.Arf Protects Tumor-Infiltrating Lymphocytes from Metabolic Exhaustion
2020-11-01
1
Hypoxia Induces Resistance to EGFR Inhibitors in Lung Cancer Cells via Upregulation of FGFR1 and the MAPK Pathway
2020-11-01
0.75
Integrated Genomic Characterization of the Human Immunome in Cancer
2020-11-01
1
KDM5B Is Essential for the Hyperactivation of PI3K/AKT Signaling in Prostate Tumorigenesis
2020-11-01
1
Oncogenic TRIM37 Links Chemoresistance and Metastatic Fate in Triple-Negative Breast Cancer
2020-11-01
0.87
PET Reporter Gene Imaging and Ganciclovir-Mediated Ablation of Chimeric Antigen Receptor T Cells in Solid Tumors
2020-11-01
1
The Alternative Splicing Factor, MBNL1, Inhibits Glioblastoma Tumor Initiation and Progression by Reducing Hypoxia-Induced Stemness
2020-11-01
1
Visualization of Activated T Cells by OX40-ImmunoPET as a Strategy for Diagnosis of Acute Graft-versus-Host Disease
2020-11-01
1
YAP-Mediated Repression of HRK Regulates Tumor Growth, Therapy Response, and Survival Under Tumor Environmental Stress in Neuroblastoma
2020-11-01
1
A Transcriptome-Wide Association Study Identifies Candidate Susceptibility Genes for Pancreatic Cancer Risk
2020-10-15
0.81
ALPPL2 Is a Highly Specific and Targetable Tumor Cell Surface Antigen
2020-10-15
1
An Integrative Gene Expression and Mathematical Flux Balance Analysis Identifies Targetable Redox Vulnerabilities in Melanoma Cells
2020-10-15
1
ERINA Is an Estrogen-Responsive LncRNA That Drives Breast Cancer through the E2F1/RB1 Pathway
2020-10-15
0.83
EZH2-Mediated Downregulation of the Tumor Suppressor DAB2IP Maintains Ovarian Cancer Stem Cells
2020-10-15
1
Genomic Predictors of Good Outcome, Recurrence, or Progression in High-Grade T1 Non–Muscle-Invasive Bladder Cancer
2020-10-15
0.61
Genomic and Epigenomic Landscaping Defines New Therapeutic Targets for Adenosquamous Carcinoma of the Pancreas
2020-10-15
1
Inhibition of the MYC-regulated glutaminase metabolic axis is an effective synthetic lethal approach for treating chemoresistant cancers
2020-10-15
0.87
Intake of Dietary Fruit, Vegetables, and Fiber and Risk of Colorectal Cancer According to Molecular Subtypes: A Pooled Analysis of 9 Studies
2020-10-15
0.67
Methylation of HSP70 Orchestrates Its Binding to and Stabilization of BCL2 mRNA and Renders Pancreatic Cancer Cells Resistant to Therapeutics
2020-10-15
1
Multiomic Analysis of Subtype Evolution and Heterogeneity in High-Grade Serous Ovarian Carcinoma
2020-10-15
1
STAT3 and GR cooperate to drive gene expression and growth of basal-like triple-negative breast cancer
2020-10-15
1
Targeting Obesity-Induced Macrophages during Preneoplastic Growth Promotes Mammary Epithelial Stem/Progenitor Activity, DNA Damage, and Tumor Formation
2020-10-15
1
The Inhibitor of Apoptosis Protein Livin Confers Resistance to Fas-Mediated Immune Cytotoxicity in Refractory Lymphoma
2020-10-15
0.08
A Division of Labor between YAP and TAZ in Non–Small Cell Lung Cancer
2020-10-01
0.20
A Proof of Concept for Biomarker-Guided Targeted Therapy against Ovarian Cancer Based on Patient-Derived Tumor Xenografts
2020-10-01
1
A Tissue-Engineered 3D Microvessel Model Reveals the Dynamics of Mosaic Vessel Formation in Breast Cancer
2020-10-01
1
ARC Is a Critical Protector against Inflammatory Bowel Disease (IBD) and IBD-Associated Colorectal Tumorigenesis
2020-10-01
0.93
Ablation of the Brca1–Palb2 Interaction Phenocopies Fanconi Anemia in Mice
2020-10-01
0.95
Aquaporin-7 Regulates the Response to Cellular Stress in Breast Cancer
2020-10-01
1
Cancer Cell CD44 Mediates Macrophage/Monocyte-Driven Regulation of Head and Neck Cancer Stem Cells
2020-10-01
0.91
Endothelin-1–Mediated Drug Resistance in EGFR-Mutant Non-Small Cell Lung Carcinoma
2020-10-01
0.37
Extracellular Vesicle–Derived miR-124 Resolves Radiation-Induced Brain Injury
2020-10-01
1
Leveraging Systematic Functional Analysis to Benchmark an In Silico Framework Distinguishes Driver from Passenger MEK Mutants in Cancer
2020-10-01
0.93
Pyrvinium Pamoate Induces Death of Triple-Negative Breast Cancer Stem–Like Cells and Reduces Metastases through Effects on Lipid Anabolism
2020-10-01
0.17
SUMOylation of E2F1 Regulates Expression of EZH2
2020-10-01
1
Soft Microenvironments Induce Chemoresistance by Increasing Autophagy Downstream of Integrin-Linked Kinase
2020-10-01
1
Structural Optimization and Enhanced Prodrug-Mediated Delivery Overcomes Camptothecin Resistance in High-Risk Solid Tumors
2020-10-01
1
Y Chromosome LncRNA Are Involved in Radiation Response of Male Non–Small Cell Lung Cancer Cells
2020-10-01
1
A Genetic Vaccine Encoding Shared Cancer Neoantigens to Treat Tumors with Microsatellite Instability
2020-09-15
0.03
Accumulation of Molecular Aberrations Distinctive to Hepatocellular Carcinoma Progression
2020-09-15
0.16
BRG1 Loss Predisposes Lung Cancers to Replicative Stress and ATR Dependency
2020-09-15
1
CHD4 Promotes Breast Cancer Progression as a Coactivator of Hypoxia-Inducible Factors
2020-09-15
1
Genome-Wide Association Study Data Reveal Genetic Susceptibility to Chronic Inflammatory Intestinal Diseases and Pancreatic Ductal Adenocarcinoma Risk
2020-09-15
0.73
Glucose-6-Phosphate Dehydrogenase Is Not Essential for K-Ras–Driven Tumor Growth or Metastasis
2020-09-15
1
IL6 Fuels Durable Memory for Th17 Cell–Mediated Responses to Tumors
2020-09-15
1
Interaction with CD68 and regulation of GAS6 expression by endosialin in fibroblasts drives recruitment and polarization of macrophages in hepatocellular carcinoma
2020-09-15
0.21
RAD51AP1 deficiency reduces tumor growth by targeting stem cell self-renewal
2020-09-15
1
The D2 and D3 Sublineages of Human Papilloma Virus 16–Positive Cervical Cancer in Guatemala Differ in Integration Rate and Age of Diagnosis
2020-09-15
0.85
The Myc and Ras Partnership in Cancer: Indistinguishable Alliance or Contextual Relationship?
2020-09-15
1
YAP Enhances Tumor Cell Dissemination by Promoting Intravascular Motility and Reentry into Systemic Circulation
2020-09-15
1
ΔNp63-Regulated Epithelial-to-Mesenchymal Transition State Heterogeneity Confers a Leader–Follower Relationship That Drives Collective Invasion
2020-09-15
1
A Novel Locus Predicts Spermatogenic Recovery among Childhood Cancer Survivors Exposed to Alkylating Agents
2020-09-01
0.83
A Rare TP53 Mutation Predominant in Ashkenazi Jews Confers Risk of Multiple Cancers
2020-09-01
1
Bromodomain-Selective BET Inhibitors Are Potent Antitumor Agents against MYC-Driven Pediatric Cancer
2020-09-01
1
Calibration of Pathogenicity Due to Variant-Induced Leaky Splicing Defects by Using BRCA2 Exon 3 as a Model System
2020-09-01
0.13
Cancer-Associated Point Mutations in the DLC1 Tumor Suppressor and Other Rho-GAPs Occur Frequently and Are Associated with Decreased Function
2020-09-01
1
Cellular Senescence Promotes Skin Carcinogenesis through p38MAPK and p44/42MAPK Signaling
2020-09-01
0.90
Deletion of Glutathione S-Transferase Omega 1 Activates Type I Interferon Genes and Downregulates Tissue Factor
2020-09-01
1
Epigenetic CRISPR Screens Identify Npm1 as a Therapeutic Vulnerability in Non–Small Cell Lung Cancer
2020-09-01
0.90
FIP200 Suppresses Immune Checkpoint Therapy Responses in Breast Cancers by Limiting AZI2/TBK1/IRF Signaling Independent of Its Canonical Autophagy Function
2020-09-01
0.86
HDAC6 Plays a Noncanonical Role in the Regulation of Antitumor Immune Responses, Dissemination, and Invasiveness of Breast Cancer
2020-09-01
1
KRASQ61H preferentially signals through MAPK in a RAF dimer-dependent manner in non-small cell lung cancer
2020-09-01
0.77
Mutant FOXL2C134W Hijacks SMAD4 and SMAD2/3 to Drive Adult Granulosa Cell Tumors
2020-09-01
0.41
Nitrogen Trapping as a Therapeutic Strategy in Tumors with Mitochondrial Dysfunction
2020-09-01
1
Oxygen-Enhanced Optoacoustic Tomography Reveals the Effectiveness of Targeting Heme and Oxidative Phosphorylation at Normalizing Tumor Vascular Oxygenation
2020-09-01
0.84
Physical Activity Does Not Lower the Risk of Lung Cancer
2020-09-01
0.13
The Synthetic Small Molecule FL3 Combats Intestinal Tumorigenesis via Axin1-Mediated Inhibition of Wnt/β-Catenin Signaling
2020-09-01
0.80
A Genome-Wide Pooled shRNA Screen Identifies PPP2R2A as a Predictive Biomarker for the Response to ATR and CHK1 Inhibitors
2020-08-15
1
ATF3 Coordinates Antitumor Synergy between Epigenetic Drugs and Protein Disulfide Isomerase Inhibitors
2020-08-15
1
Extracellular Vesicles from Cancer-Associated Fibroblasts Containing Annexin A6 Induces FAK-YAP Activation by Stabilizing β1 Integrin, Enhancing Drug Resistance
2020-08-15
0.07
Extracellular-Regulated Protein Kinase 5-Mediated Control of p21 Expression Promotes Macrophage Proliferation Associated with Tumor Growth and Metastasis
2020-08-15
0.23
FTO-Dependent N6-Methyladenosine Modifications Inhibit Ovarian Cancer Stem Cell Self-Renewal by Blocking cAMP Signaling
2020-08-15
1
HDAC10 Regulates Cancer Stem-Like Cell Properties in KRAS-Driven Lung Adenocarcinoma
2020-08-15
1
Obesity/Type 2 Diabetes-Associated Liver Tumors Are Sensitive to Cyclin D1 Deficiency
2020-08-15
0.92
Pharmacokinetic Profiles Determine Optimal Combination Treatment Schedules in Computational Models of Drug Resistance
2020-08-15
0.50
Senescent Stromal Cells Promote Cancer Resistance through SIRT1 Loss-Potentiated Overproduction of Small Extracellular Vesicles
2020-08-15
0.03
p38γ MAPK Is Essential for Aerobic Glycolysis and Pancreatic Tumorigenesis
2020-08-15
0.85
Autocrine IL6-Mediated Activation of the STAT3–DNMT Axis Silences the TNFα–RIP1 Necroptosis Pathway to Sustain Survival and Accumulation of Myeloid-Derived Suppressor Cells
2020-08-01
0.98
IL26, a Noncanonical Mediator of DNA Inflammatory Stimulation, Promotes TNBC Engraftment and Progression in Association with Neutrophils
2020-08-01
1
Long-Term Gemcitabine Treatment Reshapes the Pancreatic Tumor Microenvironment and Sensitizes Murine Carcinoma to Combination Immunotherapy
2020-08-01
1
Oncogenic Herpesvirus Engages Endothelial Transcription Factors SOX18 and PROX1 to Increase Viral Genome Copies and Virus Production
2020-08-01
0.07
State-Transition Analysis of Time-Sequential Gene Expression Identifies Critical Points That Predict Development of Acute Myeloid Leukemia
2020-08-01
1
The Lymphatic Cell Environment Promotes Kaposi Sarcoma Development by Prox1-Enhanced Productive Lytic Replication of Kaposi Sarcoma Herpes Virus
2020-08-01
1
p300-Mediated Acetylation of Histone Demethylase JMJD1A Prevents Its Degradation by Ubiquitin Ligase STUB1 and Enhances Its Activity in Prostate Cancer
2020-08-01
0.69
HACE1 Prevents Lung Carcinogenesis via Inhibition of RAC-Family GTPases
2020-07-15
0.09
ICOS Is an Indicator of T-cell–Mediated Response to Cancer Immunotherapy
2020-07-15
0.88
Inactivation of the Prolyl Isomerase Pin1 Sensitizes BRCA1-Proficient Breast Cancer to PARP Inhibition
2020-07-15
0.57
Targeting Hippo-Dependent and Hippo-Independent YAP1 Signaling for the Treatment of Childhood Rhabdomyosarcoma
2020-07-15
1
The EMT Transcription Factor ZEB2 Promotes Proliferation of Primary and Metastatic Melanoma While Suppressing an Invasive, Mesenchymal-Like Phenotype
2020-07-15
0.03
A Premalignant Cell-Based Model for Functionalization and Classification of PTEN Variants
2020-07-01
0.20
Allosteric Inhibition of SHP2 Stimulates Antitumor Immunity by Transforming the Immunosuppressive Environment
2020-07-01
1
Cancer Exacerbates Chemotherapy-Induced Sensory Neuropathy
2020-07-01
1
Lineage-Specific Epigenomic and Genomic Activation of Oncogene HNF4A Promotes Gastrointestinal Adenocarcinomas
2020-07-01
0.46
Loss of a Negative Feedback Loop between IRF8 and AR Promotes Prostate Cancer Growth and Enzalutamide Resistance
2020-07-01
0.06
Pattern of Invasion in Human Pancreatic Cancer Organoids Is Associated with Loss of SMAD4 and Clinical Outcome
2020-07-01
0.77
RNF168-Mediated Ubiquitin Signaling Inhibits the Viability of BRCA1-Null Cancers
2020-07-01
0.88
Spatiotemporal Regulation of ΔNp63 by TGFβ-Regulated miRNAs Is Essential for Cancer Metastasis
2020-07-01
1
The PET-Tracer 89Zr-Df-IAB22M2C Enables Monitoring of Intratumoral CD8 T-cell Infiltrates in Tumor-Bearing Humanized Mice after T-cell Bispecific Antibody Treatment
2020-07-01
0.45
Therapeutic Targeting of the Secreted Lysophospholipase D Autotaxin Suppresses Tuberous Sclerosis Complex-Associated Tumorigenesis
2020-07-01
1
A Genome-Wide Association Study Identifies Two Novel Susceptible Regions for Squamous Cell Carcinoma of the Head and Neck
2020-06-15
1
Activation of a Subset of Evolutionarily Young Transposable Elements and Innate Immunity Are Linked to Clinical Responses to 5-Azacytidine
2020-06-15
0.50
Consumption of the Fish Oil High-Fat Diet Uncouples Obesity and Mammary Tumor Growth through Induction of Reactive Oxygen Species in Protumor Macrophages
2020-06-15
0.81
EIF3H Orchestrates Hippo Pathway–Mediated Oncogenesis via Catalytic Control of YAP Stability
2020-06-15
0.64
FBXW7 Triggers Degradation of KMT2D to Favor Growth of Diffuse Large B-cell Lymphoma Cells
2020-06-15
1
Identification of a Small-Molecule Inhibitor That Disrupts the SIX1/EYA2 Complex, EMT, and Metastasis
2020-06-15
1
Induction of DNMT3B by PGE2 and IL6 at Distant Metastatic Sites Promotes Epigenetic Modification and Breast Cancer Colonization
2020-06-15
1
Myeloid Cell–Derived TGFβ Signaling Regulates ECM Deposition in Mammary Carcinoma via Adenosine-Dependent Mechanisms
2020-06-15
1
Rb and p53-Deficient Myxofibrosarcoma and Undifferentiated Pleomorphic Sarcoma Require Skp2 for Survival
2020-06-15
1
TAp63-Regulated miRNAs Suppress Cutaneous Squamous Cell Carcinoma through Inhibition of a Network of Cell-Cycle Genes
2020-06-15
1
Telomere Maintenance Mechanisms Define Clinical Outcome in High-Risk Neuroblastoma
2020-06-15
0.95
YAP-Mediated Recruitment of YY1 and EZH2 Represses Transcription of Key Cell-Cycle Regulators
2020-06-15
1
A Feedback loop comprising EGF/TGF-α Sustains TFCP2-mediated Breast Cancer Progression
2020-06-01
0.11
ATM Loss Confers Greater Sensitivity to ATR Inhibition Than PARP Inhibition in Prostate Cancer
2020-06-01
1
BRD4 Levels Determine the Response of Human Lung Cancer Cells to BET Degraders That Potently Induce Apoptosis through Suppression of Mcl-1
2020-06-01
0.67
GPD1 Enhances the Anticancer Effects of Metformin by Synergistically Increasing Total Cellular Glycerol-3-Phosphate
2020-06-01
0.19
Golgi-Localized PAQR4 Mediates Antiapoptotic Ceramidase Activity in Breast Cancer
2020-06-01
0.20
H2A Monoubiquitination Links Glucose Availability to Epigenetic Regulation of the Endoplasmic Reticulum Stress Response and Cancer Cell Death
2020-06-01
1
Hispanic/Latino Patients with Gastric Adenocarcinoma Have Distinct Molecular Profiles Including a High Rate of Germline CDH1 Variants
2020-06-01
1
IRE1α Disruption in Triple-Negative Breast Cancer Cooperates with Antiangiogenic Therapy by Reversing ER Stress Adaptation and Remodeling the Tumor Microenvironment
2020-06-01
1
Molecular Imaging of the Tumor Microenvironment Reveals the Relationship between Tumor Oxygenation, Glucose Uptake, and Glycolysis in Pancreatic Ductal Adenocarcinoma
2020-06-01
1
Peptidylarginine deiminase IV (PADI4) regulates breast cancer stem cells via a novel tumor cell-autonomous suppressor role
2020-06-01
1
Systematic Establishment of Robustness and Standards in Patient-Derived Xenograft Experiments and Analysis
2020-06-01
1
Targeted Inhibition of the E3 Ligase SCFSkp2/Cks1 Has Antitumor Activity in RB1-Deficient Human and Mouse Small-Cell Lung Cancer
2020-06-01
1
Targeting glycosylated PD-1 induces potent anti-tumor immunity
2020-06-01
0.79
A Protease-Activated Fluorescent Probe Allows Rapid Visualization of Keratinocyte Carcinoma during Excision
2020-05-15
1
Blocking SHH/Patched Interaction Triggers Tumor Growth Inhibition through Patched-Induced Apoptosis
2020-05-15
0.13
Drug Sensitivity and Allele Specificity of First-Line Osimertinib Resistance EGFR Mutations
2020-05-15
0.71
Endonuclease FEN1 Coregulates ERα Activity and Provides a Novel Drug Interface in Tamoxifen-Resistant Breast Cancer
2020-05-15
0.23
Melanoma-Secreted Lysosomes Trigger Monocyte-Derived Dendritic Cell Apoptosis and Limit Cancer Immunotherapy
2020-05-15
0.13
Perineural invasion reprograms the immune microenvironment through cholinergic signaling in pancreatic ductal adenocarcinoma
2020-05-15
0.02
Targeting of CD38 by the tumor suppressor miR-26a serves as a novel potential therapeutic agent in multiple myeloma
2020-05-15
0.86
Glial TIM-3 modulates immune responses in the brain tumor microenvironment
2020-05-01
0.11
Human Epidermal Growth Factor Receptor 2–Positive Breast Cancer Is Associated with Indigenous American Ancestry in Latin American Women
2020-05-01
0.40
MEF2c-Dependent Downregulation of Myocilin Mediates Cancer-Induced Muscle Wasting and Associates with Cachexia in Patients with Cancer
2020-05-01
1
NOX4 Inhibition Potentiates Immunotherapy by Overcoming Cancer-Associated Fibroblast-Mediated CD8 T-cell Exclusion from Tumors
2020-05-01
0.11
Targeting the E3 Ubiquitin Ligase PJA1 Enhances Tumor-Suppressing TGFβ Signaling
2020-05-01
1
A Sox2:miR-486-5p Axis Regulates Survival of GBM Cells by Inhibiting Tumor Suppressor Networks
2020-04-15
1
ATM Paradoxically Promotes Oncogenic Transformation via Transcriptional Reprogramming
2020-04-15
0.81
Adipocyte-Induced FABP4 Expression in Ovarian Cancer Cells Promotes Metastasis and Mediates Carboplatin Resistance
2020-04-15
1
LIN9 and NEK2 Are Core Regulators of Mitotic Fidelity That Can Be Therapeutically Targeted to Overcome Taxane Resistance
2020-04-15
1
The tumor suppressor BAP1 regulates the Hippo pathway in pancreatic ductal adenocarcinoma
2020-04-15
1
Undermining Glutaminolysis Bolsters Chemotherapy While NRF2 Promotes Chemoresistance in KRAS-Driven Pancreatic Cancers
2020-04-15
1
iNOS Regulates the Therapeutic Response of Pancreatic Cancer Cells to Radiotherapy
2020-04-15
1
An ABC Transporter Drives Medulloblastoma Pathogenesis by Regulating Sonic Hedgehog Signaling
2020-04-01
1
Cancer Cell–Derived Matrisome Proteins Promote Metastasis in Pancreatic Ductal Adenocarcinoma
2020-04-01
0.76
Clonal ZEB1-Driven Mesenchymal Transition Promotes Targetable Oncologic Antiangiogenic Therapy Resistance
2020-04-01
1
Dual Oxidase-Induced Sustained Generation of Hydrogen Peroxide Contributes to Pharmacologic Ascorbate-Induced Cytotoxicity
2020-04-01
1
Enhanced Lipid Accumulation and Metabolism Are Required for the Differentiation and Activation of Tumor-Associated Macrophages
2020-04-01
1
In Silico Models Accurately Predict In Vivo Response for IL6 Blockade in Head and Neck Cancer
2020-04-01
1
Inhibition of BCL2 Family Members Increases the Efficacy of Copper Chelation in BRAFV600E-Driven Melanoma
2020-04-01
1
Oncogenic ERG Represses PI3K Signaling through Downregulation of IRS2
2020-04-01
1
Proteomic Profiling of the ECM of Xenograft Breast Cancer Metastases in Different Organs Reveals Distinct Metastatic Niches
2020-04-01
1
Single-cell Proteomic Profiling Identifies Combined AXL and JAK1 Inhibition as a Novel Therapeutic Strategy for Lung Cancer
2020-04-01
0.94
Towards Multidrug Adaptive Therapy
2020-04-01
0.86
A Prospective Analysis of Circulating Plasma Metabolites Associated with Ovarian Cancer Risk
2020-03-15
1
Activation of Canonical BMP4-SMAD7 Signaling Suppresses Breast Cancer Metastasis
2020-03-15
0.13
ETV4 Is Necessary for Estrogen Signaling and Growth in Endometrial Cancer Cells
2020-03-15
1
Increased Tumor Penetration of Single-Domain Antibody–Drug Conjugates Improves In Vivo Efficacy in Prostate Cancer Models
2020-03-15
0.58
Localized metabolomic gradients in patient-derived xenograft models of glioblastoma
2020-03-15
1
The MEK5–ERK5 Kinase Axis Controls Lipid Metabolism in Small-Cell Lung Cancer
2020-03-15
0.92
A Bis-Indole–Derived NR4A1 Antagonist Induces PD-L1 Degradation and Enhances Antitumor Immunity
2020-03-01
1
ARRB1-promoted NOTCH1 degradation is suppressed by oncomiR miR-223 in T cell acute lymphoblastic leukemia
2020-03-01
0.06
Epigenetic Targeting of TERT-Associated Gene Expression Signature in Human Neuroblastoma with TERT Overexpression
2020-03-01
1
HIF2-Induced Long Noncoding RNA RAB11B-AS1 Promotes Hypoxia-Mediated Angiogenesis and Breast Cancer Metastasis
2020-03-01
1
Host Wnt5a Potentiates Microenvironmental Regulation of Ovarian Cancer Metastasis
2020-03-01
1
Inhibiting Translation Elongation with SVC112 Suppresses Cancer Stem Cells and Inhibits Growth in Head and Neck Squamous Carcinoma
2020-03-01
1
Linking Transcriptomic and Imaging Data Defines Features of a Favorable Tumor Immune Microenvironment and Identifies a Combination Biomarker for Primary Melanoma
2020-03-01
0.88
Long Noncoding RNA DRAIC Inhibits Prostate Cancer Progression by Interacting with IKK to Inhibit NF-κB Activation
2020-03-01
1
Metabolic Reprogramming in Cancer Is Induced to Increase Proton Production
2020-03-01
0.50
Mitochondrial haplotype of the host stromal microenvironment alters metastasis in a non-cell autonomous manner
2020-03-01
1
Nudix Hydrolase NUDT16 Regulates 53BP1 Protein by Reversing 53BP1 ADP-Ribosylation
2020-03-01
1
Runx2 Deficiency in Osteoblasts Promotes Myeloma Progression by Altering the Bone Microenvironment at New Bone Sites
2020-03-01
0.78
SLC43A3 Is a Biomarker of Sensitivity to the Telomeric DNA Damage Mediator 6-Thio-2′-Deoxyguanosine
2020-03-01
1
The Immunosuppressive Microenvironment in BRCA1-IRIS–Overexpressing TNBC Tumors Is Induced by Bidirectional Interaction with Tumor-Associated Macrophages
2020-03-01
1
The Risk of Ovarian Cancer Increases with an Increase in the Lifetime Number of Ovulatory Cycles: An Analysis from the Ovarian Cancer Cohort Consortium (OC3)
2020-03-01
0.59
Therapy-Induced Senescence Drives Bone Loss
2020-03-01
1
Tumor Cell–Derived IL1β Promotes Desmoplasia and Immune Suppression in Pancreatic Cancer
2020-03-01
1
Wnt-Induced Stabilization of KDM4C Is Required for Wnt/β-Catenin Target Gene Expression and Glioblastoma Tumorigenesis
2020-03-01
1
Cell adhesiveness serves as a biophysical marker for metastatic potential
2020-02-15
1
Cooperative blockade of PKCα and JAK2 drives apoptosis in glioblastoma
2020-02-15
0.96
HPV16 E5 Mediates Resistance to PD-L1 Blockade and can be targeted with Rimantadine in Head and Neck Cancer
2020-02-15
0.80
Inhibition of Haspin kinase promotes cell-intrinsic and extrinsic anti-tumor activity.
2020-02-15
0.83
Integrin β4-targeted cancer immunotherapies inhibit tumor growth and decrease metastasis
2020-02-15
0.50
Interleukin-6/STAT3 Signaling Orchestrates Pre-metastatic Niche Formation and Immunosuppressive Traits in Lung
2020-02-15
0.06
Mass Spectrometry Imaging enables Discrimination of Renal Oncocytoma from Renal Cell Cancer Subtypes and Normal Kidney Tissues
2020-02-15
1
Mathematical Modeling of Pre-Clinical Alpha-Emitter Radiopharmaceutical Therapy
2020-02-15
0.75
Murine Oviductal High-Grade Serous Carcinomas Mirror the Genomic Alterations, Gene Expression Profiles, and Immune Microenvironment of Their Human Counterparts
2020-02-15
1
NAMPT inhibition suppresses cancer stem-like cells associated with therapy-induced senescence in ovarian cancer
2020-02-15
1
Rare BRIP1 missense alleles confer risk for ovarian and breast cancer
2020-02-15
1
Sustained Co-evolution in a Stochastic Model of Cancer-Immune Interaction
2020-02-15
1
A Novel Bioengineered MicroRNA-127 Prodrug Suppresses The Growth And Metastatic Potential Of Triple Negative Breast Cancer Cells
2020-02-01
1
A Small Molecule Inhibitor Targeting TRIP13 suppresses multiple myeloma progression
2020-02-01
0.12
Acquired resistance to HER2-targeted therapies creates vulnerability to ATP synthase inhibition
2020-02-01
0.88
Argonautes in extracellular vesicles: artifact or selected cargo?
2020-02-01
1
Association of Genomic Domains in BRCA1 and BRCA2 with Prostate Cancer Risk and Aggressiveness
2020-02-01
0.15
Dysregulation of glutamate transport enhances Treg function that promotes VEGF blockade resistance in glioblastoma
2020-02-01
0.69
Eradicating metastatic cancer and the eco-evolutionary dynamics of Anthropocene extinctions
2020-02-01
0.80
Gain-of-Function Mutant p53 R273H Interacts with Replicating DNA and PARP1 in Breast Cancer
2020-02-01
1
Genome-wide CRISPR-Cas9 screen reveals selective vulnerability of ATRX-mutant cancers to WEE1 inhibition
2020-02-01
0.14
Metastatic conditioning of myeloid cells at a subcutaneous synthetic niche reflects disease progression and predicts therapeutic outcomes
2020-02-01
1
Modeling tumor evolutionary dynamics to predict clinical outcomes for patients with metastatic colorectal cancer: a retrospective analysis
2020-02-01
1
Prophylactic in vivo hematopoietic stem cell gene therapy with an immune checkpoint inhibitor reverses tumor growth in syngeneic mouse tumor models
2020-02-01
0.83
Single-cell gene expression analyses reveal distinct self-renewing and proliferating subsets in the leukemia stem cell compartment in acute myeloid leukemia
2020-02-01
1
Transcriptionally Active Androgen Receptor Splice Variants Promote Hepatocellular Carcinoma Progression
2020-02-01
0.73
USP22 functions as an oncogenic driver in prostate cancer by regulating cell proliferation and DNA repair
2020-02-01
1
An engineered tumor-on-a-chip device with breast cancer-immune cell interactions for assessing T-cell recruitment
2020-01-15
1
Beclin 1 promotes endosome recruitment of hepatocyte growth factor tyrosine kinase substrate (HRS) to suppress tumor proliferation
2020-01-15
1
Bi-directional regulation between NDRG1 and GSK3β controls tumor growth and is targeted by differentiation inducing factor-1 in glioblastoma
2020-01-15
0.09
Clinical Evolution of Epithelial-Mesenchymal Transition in Human Carcinomas
2020-01-15
1
CoA Synthase (COASY) mediates radiation resistance via PI3K signaling in rectal cancer
2020-01-15
1
Differential Contributions of Pre- and Post-EMT Tumor Cells in Breast Cancer Metastasis
2020-01-15
0.96
Molecular Profiles of Matched Primary and Metastatic Tumor Samples Support a Linear Evolutionary Model of Breast Cancer
2020-01-15
1
Penetrance estimates over time to first and second primary cancer diagnosis in families with Li-Fraumeni syndrome: a single institution perspective
2020-01-15
0.95
Penetrance of different cancer types in families with Li-Fraumeni syndrome: a validation study using multi-center cohorts
2020-01-15
0.83
Photodynamic Therapy is an Effective Adjuvant Therapy for Image-Guided Surgery in Prostate Cancer
2020-01-15
1
RNA-binding protein ZFP36L1 suppresses hypoxia and cell cycle signaling
2020-01-15
0.20
Targeting the Metabolic Response to Statin-Mediated Oxidative Stress Produces a Synergistic Antitumor Response
2020-01-15
0.03
Twist1-induced epithelial dissemination requires Prkd1 signaling
2020-01-15
0.96
A Single-Step, High-Dose Selection Scheme Reveals Distinct Mechanisms of Acquired Resistance to Oncogenic Kinase Inhibition in Cancer Cells
2020-01-01
1
Heparanase and Chemotherapy Synergize to Drive Macrophage Activation and Enhance Tumor Growth
2020-01-01
0.08
MET Inhibition Elicits PGC1α-Dependent Metabolic Reprogramming in Glioblastoma
2020-01-01
0.89
Novel mechanisms of cancer emerge when accounting for sex as a biological variable
2020-01-01
1
Phosphorylation of RAB7 by TBK1/IKKε Regulates Innate Immune Signaling in Triple-Negative Breast Cancer
2020-01-01
0.96
Recreational Physical Activity Is Associated with Reduced Breast Cancer Risk in Adult Women at High Risk for Breast Cancer: A Cohort Study of Women Selected for Familial and Genetic Risk
2020-01-01
0.40
Suppression of LIM Kinase 1 and LIM Kinase 2 Limits Glioblastoma Invasion
2020-01-01
1
Targeting Novel Sodium Iodide Symporter Interactors ADP-Ribosylation Factor 4 and Valosin-Containing Protein Enhances Radioiodine Uptake
2020-01-01
0.18
Epigenomic Profiling Discovers Trans-lineage SOX2 Partnerships Driving Tumor Heterogeneity in Lung Squamous Cell Carcinoma
2019-12-15
0.82
MFF Regulation of Mitochondrial Cell Death Is a Therapeutic Target in Cancer
2019-12-15
0.65
Mcl-1 interacts with Akt to promote lung cancer progression
2019-12-15
1
Parallel signaling through IRE1α and PERK regulates pancreatic neuroendocrine tumor growth and survival
2019-12-15
1
YAP1 mediates resistance to MEK1/2 inhibition in neuroblastomas with hyperactivated RAS signalling
2019-12-15
1
BRCA1 Deficiency Upregulates NNMT, Which Reprograms Metabolism and Sensitizes Ovarian Cancer Cells to Mitochondrial Metabolic Targeting Agents
2019-12-01
1
Cleaved Caspase-3 Transcriptionally Regulates Angiogenesis-Promoting Chemotherapy Resistance
2019-12-01
0.06
Clonal Mutations Activate the NF-κB Pathway to Promote Recurrence of Nasopharyngeal Carcinoma
2019-12-01
0.03
Cys34 Adductomics Links Colorectal Cancer with the Gut Microbiota and Redox Biology
2019-12-01
0.44
Gastrointestinal Tract Dysbiosis Enhances Distal Tumor Progression through Suppression of Leukocyte Trafficking
2019-12-01
1
Integrated Pan-Cancer Map of EBV-Associated Neoplasms Reveals Functional Host–Virus Interactions
2019-12-01
1
Radiation Drives the Evolution of Orthotopic Xenografts Initiated from Glioblastoma Stem–like Cells
2019-12-01
0.96
Syndecan-Mediated Ligation of ECM Proteins Triggers Proliferative Arrest of Disseminated Tumor Cells
2019-12-01
1
286 222.26
98 73.98
93 64.78
102 81.37
1 1
290 206.53
119 97.31
70 44.50
1 0.44
72 61.25
98 69.18
88 68.97
789 660.54
139 109.68
370 282.30
123 83.23
416 350.22
180 140.73
162 112.95
477 328.90
99 78.77
72 51.49
109 84.90
2186 1421.72
92 55.28
1 0.83
78 51.61
153 105.50
74 60.03
108 85.85
81 64.61
213 182.14
156 106.03
284 216.28
1922 1480.98
265 182.56
328 233.82
699 499.53
217 169.33
99 47.48
118 85.79
71 40.81
1084 890.33
Earth & Environmental Sciences 4341 2853.57
Chemistry 7235 5250.77
Physical Sciences 8259 5364.59

1 December 2019 - 30 November 2020

View the connected world of international research collaboration. Visualize collaborations by subject or region.

Collaborations between countries

Percentage of collaboration by Share

Hover over the graph to view the percentage of collaboration.

Top 10 collaborators by Share

  • United States of America (USA)
  1. China (4420.77)
    2106.75
    2314.03
  2. 1144.34
    831.17
  3. Germany (1914.97)
    1082.34
    832.63
  4. Canada (1205.80)
    753.10
    452.71
  5. France (1078.91)
    656.65
    422.26
  6. Japan (974.94)
    598.68
    376.26
  7. Australia (712.66)
    427.56
    285.10
  8. Switzerland (698.47)
    414.10
    284.37
  9. South Korea (697.43)
    420.77
    276.66
  10. Italy (582.81)
    354.79
    228.01

Collaboration is determined by the combined fractional count (Share) of United States of America (USA) and the collaborating country.

Top 10 institutions from United States of America (USA)

Institution Count Share
1. Harvard University 2535 914
2. Stanford University 1694 647.18
3. Massachusetts Institute of Technology (MIT) 1828 528.46
4. National Institutes of Health (NIH) 1085 404.29
5. University of California, Berkeley (UC Berkeley) 1297 395.84
6. University of Michigan (U-M) 1010 391.33
7. Yale University 987 350.79
8. University of California, San Diego (UC San Diego) 1003 342.66
9. Columbia University in the City of New York (CU) 1027 327.89
10. University of California, Los Angeles (UCLA) 1114 327.29

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