United Kingdom (UK)

1 September 2020 - 31 August 2021

Subject/journal group: All

The table to the right includes counts of all research outputs for United Kingdom (UK) published between 1 September 2020 - 31 August 2021 which are tracked by the Nature Index.

Hover over the donut graph to view the FC output for each subject. Below, the same research outputs are grouped by subject. Click on the subject to drill-down into a list of articles organized by journal, and then by title.

Note: Articles may be assigned to more than one subject area.

Count Share
7835 3626.68

Outputs by subject (FC)

Subject Count Share
Life Sciences 3576 1626.02
56 12.39
9 2.81
36 16.07
69 23.73
10 3.73
15 5.44
26 12.68
101 49.65
26 13.81
43 17.95
12 7.01
29 15.69
13 6.95
92 51.11
45 28.22
44 12.09
31 10.77
88 49.59
44 20.84
59 20.76
151 63.70
19 4.26
17 8.53
9 2.79
879 382.37
Large uncertainties in trends of energy demand for heating and cooling under climate change
2021-08-31
0.20
Molecular and functional profiling identifies therapeutically targetable vulnerabilities in plasmablastic lymphoma
2021-08-31
0.05
Neural signatures of hyperdirect pathway activity in Parkinson’s disease
2021-08-31
0.56
A nutrient-responsive hormonal circuit mediates an inter-tissue program regulating metabolic homeostasis in adult Drosophila
2021-08-30
0.38
A pre-registered short-term forecasting study of COVID-19 in Germany and Poland during the second wave
2021-08-27
0.07
Intravital imaging of islet Ca2+ dynamics reveals enhanced β cell connectivity after bariatric surgery in mice
2021-08-27
0.76
The structure of the bacterial DNA segregation ATPase filament reveals the conformational plasticity of ParA upon DNA binding
2021-08-27
1
Bioengineered embryoids mimic post-implantation development in vitro
2021-08-26
0.14
Distinct patterns of within-host virus populations between two subgroups of human respiratory syncytial virus
2021-08-26
0.49
Opposing roles for striatonigral and striatopallidal neurons in dorsolateral striatum in consolidating new instrumental actions
2021-08-25
0.13
T cell receptor recognition of hybrid insulin peptides bound to HLA-DQ8
2021-08-25
0.02
Comprehensive characterization of 536 patient-derived xenograft models prioritizes candidatesfor targeted treatment
2021-08-24
0
Deciphering ion transport and ATPase coupling in the intersubunit tunnel of KdpFABC
2021-08-24
0.29
AMPA receptor anchoring at CA1 synapses is determined by N-terminal domain and TARP γ8 interactions
2021-08-23
1
UbiD domain dynamics underpins aromatic decarboxylation
2021-08-20
1
Bacterial cellulose spheroids as building blocks for 3D and patterned living materials and for regeneration
2021-08-19
1
Somatic genetic rescue of a germline ribosome assembly defect
2021-08-19
0.30
The MURAL collection of prostate cancer patient-derived xenografts enables discovery through preclinical models of uro-oncology
2021-08-19
0.01
Etiological and epidemiological features of acute respiratory infections in China
2021-08-18
0
High COVID-19 transmission potential associated with re-opening universities can be mitigated with layered interventions
2021-08-17
1
Parallel adaptation in autopolyploid Arabidopsis arenosa is dominated by repeated recruitment of shared alleles
2021-08-17
0.42
Structural basis for the inhibition of HTLV-1 integration inferred from cryo-EM deltaretroviral intasome structures
2021-08-17
0.73
Two doses of SARS-CoV-2 vaccination induce robust immune responses to emerging SARS-CoV-2 variants of concern
2021-08-17
0.97
Decline in plankton diversity and carbon flux with reduced sea ice extent along the Western Antarctic Peninsula
2021-08-16
0.09
LineageOT is a unified framework for lineage tracing and trajectory inference
2021-08-16
0.50
Mirtron-mediated RNA knockdown/replacement therapy for the treatment of dominant retinitis pigmentosa
2021-08-16
1
NGF-TrkA signaling dictates neural ingrowth and aberrant osteochondral differentiation after soft tissue trauma
2021-08-16
0.04
Offspring born to influenza A virus infected pregnant mice have increased susceptibility to viral and bacterial infections in early life
2021-08-16
0.07
A transcription-based mechanism for oncogenic β-catenin-induced lethality in BRCA1/2-deficient cells
2021-08-13
0.67
RSPO3 is important for trabecular bone and fracture risk in mice and humans
2021-08-13
0.05
The pathogenesis of mesothelioma is driven by a dysregulated translatome
2021-08-13
1
Spontaneous hydrolysis and spurious metabolic properties of α-ketoglutarate esters
2021-08-12
0.09
A last-in first-out stack data structure implemented in DNA
2021-08-11
0.86
Chd1 protects genome integrity at promoters to sustain hypertranscription in embryonic stem cells
2021-08-11
0.18
Global variation in the fraction of leaf nitrogen allocated to photosynthesis
2021-08-11
0.12
Structure, mechanism and crystallographic fragment screening of the SARS-CoV-2 NSP13 helicase
2021-08-11
0.82
Temporal omics analysis in Syrian hamsters unravel cellular effector responses to moderate COVID-19
2021-08-11
0.02
A microRNA program regulates the balance between cardiomyocyte hyperplasia and hypertrophy and stimulates cardiac regeneration
2021-08-10
0.02
Polyclonal antibody responses to HIV Env immunogens resolved using cryoEM
2021-08-10
0.06
The developing mouse coronal suture at single-cell resolution
2021-08-10
0.47
Tracking the introduction and spread of SARS-CoV-2 in coastal Kenya
2021-08-10
0.10
Two parallel pathways connect glutamine metabolism and mTORC1 activity to regulate glutamoptosis
2021-08-10
0.22
FcγR engagement reprograms neutrophils into antigen cross-presenting cells that elicit acquired anti-tumor immunity
2021-08-09
0.02
Distinct regulation of hippocampal neuroplasticity and ciliary genes by corticosteroid receptors
2021-08-06
1
Enhanced NF-κB signaling in type-2 dendritic cells at baseline predicts non-response to adalimumab in psoriasis
2021-08-06
1
Responsive core-shell DNA particles trigger lipid-membrane disruption and bacteria entrapment
2021-08-06
1
Timing the evolution of antioxidant enzymes in cyanobacteria
2021-08-06
0.50
Whole-genome sequencing of Schistosoma mansoni reveals extensive diversity with limited selection despite mass drug administration
2021-08-06
0.69
Brown adipose tissue is the key depot for glucose clearance in microbiota depleted mice
2021-08-05
0.20
COVID-19 spread, detection, and dynamics in Bogota, Colombia
2021-08-05
0.03
Puf6 primes 60S pre-ribosome nuclear export at low temperature
2021-08-04
0.17
Diffusion-mediated HEI10 coarsening can explain meiotic crossover positioning in Arabidopsis
2021-08-03
0.83
Non-invasive hydrodynamic imaging in plant roots at cellular resolution
2021-08-03
0.57
A single dose of ChAdOx1 Chik vaccine induces neutralizing antibodies against four chikungunya virus lineages in a phase 1 clinical trial
2021-07-30
0.85
Correlative multi-scale cryo-imaging unveils SARS-CoV-2 assembly and egress
2021-07-30
0.93
Exites in Cambrian arthropods and homology of arthropod limb branches
2021-07-30
0.17
Mobility patterns are associated with experienced income segregation in large US cities
2021-07-30
0.13
Plasmodium falciparum transcription in different clinical presentations of malaria associates with circulation time of infected erythrocytes
2021-07-30
0.02
The integrated stress response is tumorigenic and constitutes a therapeutic liability in KRAS-driven lung cancer
2021-07-30
0.21
Toxin import through the antibiotic efflux channel TolC
2021-07-30
1
Immune responses to a single dose of the AZD1222/Covishield vaccine in health care workers
2021-07-29
0.20
Nuclear condensates of p300 formed though the structured catalytic core can act as a storage pool of p300 with reduced HAT activity
2021-07-29
0.14
An umbrella review of the evidence associating diet and cancer risk at 11 anatomical sites
2021-07-28
0.26
Gene-drive suppression of mosquito populations in large cages as a bridge between lab and field
2021-07-28
0.46
IFITM proteins promote SARS-CoV-2 infection and are targets for virus inhibition in vitro
2021-07-28
0.02
Mechanistic insights into the three steps of poly(ADP-ribosylation) reversal
2021-07-28
0.50
Multifocal imaging for precise, label-free tracking of fast biological processes in 3D
2021-07-28
0.13
Neural and computational mechanisms of momentary fatigue and persistence in effort-based choice
2021-07-28
1
SUMOylation of SAMHD1 at Lysine 595 is required for HIV-1 restriction in non-cycling cells
2021-07-28
0.02
Chloride sensing by WNK1 regulates NLRP3 inflammasome activation and pyroptosis
2021-07-27
0.25
Correlative 3D microscopy of single cells using super-resolution and scanning ion-conductance microscopy
2021-07-27
0.18
Individual environmental niches in mobile organisms
2021-07-27
0.10
The apicoplast link to fever-survival and artemisinin-resistance in the malaria parasite
2021-07-27
0.27
The trans-omics landscape of COVID-19
2021-07-27
0.01
Transporter characterisation reveals aminoethylphosphonate mineralisation as a key step in the marine phosphorus redox cycle
2021-07-27
0.95
Unfolding the multiscale structure of networks with dynamical Ollivier-Ricci curvature
2021-07-27
0.25
Identification of 22 susceptibility loci associated with testicular germ cell tumors
2021-07-23
0.06
Identifying individuals with high risk of Alzheimer’s disease using polygenic risk scores
2021-07-23
0.71
KRAP tethers IP3 receptors to actin and licenses them to evoke cytosolic Ca2+ signals
2021-07-23
0.88
Lineage-defined leiomyosarcoma subtypes emerge years before diagnosis and determine patient survival
2021-07-23
0.06
Mechanistic insight into bacterial entrapment by septin cage reconstitution
2021-07-23
0.67
Reverse optogenetics of G protein signaling by zebrafish non-visual opsin Opn7b for synchronization of neuronal networks
2021-07-23
0.21
Strainberry: automated strain separation in low-complexity metagenomes using long reads
2021-07-23
0.25
Structural basis of intron selection by U2 snRNP in the presence of covalent inhibitors
2021-07-23
0.20
A minus-end directed kinesin motor directs gravitropism in Physcomitrella patens
2021-07-22
0.25
An on-demand, drop-on-drop method for studying enzyme catalysis by serial crystallography
2021-07-22
0.56
Structure of the mini-RNA-guided endonuclease CRISPR-Cas12j3
2021-07-22
0.06
Vulnerability of the North Water ecosystem to climate change
2021-07-22
0.07
Ageing is associated with disrupted reinforcement learning whilst learning to help others is preserved
2021-07-21
1
Reactivation of a developmentally silenced embryonic globin gene
2021-07-21
0.87
Role of Tim4 in the regulation of ABCA1+ adipose tissue macrophages and post-prandial cholesterol levels
2021-07-21
1
Targeting the latent human cytomegalovirus reservoir for T-cell-mediated killing with virus-specific nanobodies
2021-07-21
0.56
A generalizable and accessible approach to machine learning with global satellite imagery
2021-07-20
0.04
Contextualizing genetic risk score for disease screening and rare variant discovery
2021-07-20
0.07
Development and implementation of a scalable and versatile test for COVID-19 diagnostics in rural communities
2021-07-20
0.06
Dysfunction of the key ferroptosis-surveilling systems hypersensitizes mice to tubular necrosis during acute kidney injury
2021-07-20
0.01
The impact of site-specific digital histology signatures on deep learning model accuracy and bias
2021-07-20
0.03
A deep learning model for predicting next-generation sequencing depth from DNA sequence
2021-07-19
0.33
Development of a fixed module repertoire for the analysis and interpretation of blood transcriptome data
2021-07-19
0.17
Insulin protects acinar cells during pancreatitis by preserving glycolytic ATP supply to calcium pumps
2021-07-19
0.50
SARS-CoV-2 antibody dynamics and transmission from community-wide serological testing in the Italian municipality of Vo’
2021-07-19
0.15
Associations between dimensions of behaviour, personality traits, and mental-health during the COVID-19 pandemic in the United Kingdom
2021-07-16
0.88
Discovery and prioritization of variants and genes for kidney function in 1.2 million individuals
2021-07-16
0.02
Francisella tularensis induces Th1 like MAIT cells conferring protection against systemic and local infection
2021-07-16
0.02
The molecular basis of regulation of bacterial capsule assembly by Wzc
2021-07-16
0.70
Extensive transcriptional and chromatin changes underlie astrocyte maturation in vivo and in culture
2021-07-15
0.97
A prometaphase mechanism of securin destruction is essential for meiotic progression in mouse oocytes
2021-07-14
1
Chronic lung diseases are associated with gene expression programs favoring SARS-CoV-2 entry and severity
2021-07-14
0.17
Coordination of biradial-to-radial symmetry and tissue polarity by HD-ZIP II proteins
2021-07-14
0.33
Deep carbon cycle constrained by carbonate solubility
2021-07-14
0.17
Extensive standing genetic variation from a small number of founders enables rapid adaptation in Daphnia
2021-07-14
0.33
Phosphorylated tau181 in plasma as a potential biomarker for Alzheimer’s disease in adults with Down syndrome
2021-07-14
0.04
The HIF target MAFF promotes tumor invasion and metastasis through IL11 and STAT3 signaling
2021-07-14
0.06
A novel RyR1-selective inhibitor prevents and rescues sudden death in mouse models of malignant hyperthermia and heat stroke
2021-07-13
0.12
Epigenetic memories and the evolution of infectious diseases
2021-07-13
0.33
IL-15 and PIM kinases direct the metabolic programming of intestinal intraepithelial lymphocytes
2021-07-13
1
Single-nucleus RNA-seq2 reveals functional crosstalk between liver zonation and ploidy
2021-07-12
0.50
Structural basis of the membrane intramolecular transacylase reaction responsible for lyso-form lipoprotein synthesis
2021-07-12
0.22
The Welwitschia genome reveals a unique biology underpinning extreme longevity in deserts
2021-07-12
0.06
A clinical deep learning framework for continually learning from cardiac signals across diseases, time, modalities, and institutions
2021-07-09
1
A generative network model of neurodevelopmental diversity in structural brain organization
2021-07-09
1
The force loading rate drives cell mechanosensing through both reinforcement and cytoskeletal softening
2021-07-09
0.04
Different environmental variables predict body and brain size evolution in Homo
2021-07-08
0.38
A genomic surveillance framework and genotyping tool for Klebsiella pneumoniae and its related species complex
2021-07-07
0.08
Chaperone-like protein DAY plays critical roles in photomorphogenesis
2021-07-07
0.11
Cross-ancestry GWAS meta-analysis identifies six breast cancer loci in African and European ancestry women
2021-07-07
0.12
Fractional response analysis reveals logarithmic cytokine responses in cellular populations
2021-07-07
0.29
GIGYF1 loss of function is associated with clonal mosaicism and adverse metabolic health
2021-07-07
0.92
The epidemiology of Plasmodium vivax among adults in the Democratic Republic of the Congo
2021-07-07
0.16
The role of membrane destabilisation and protein dynamics in BAM catalysed OMP folding
2021-07-07
0.87
Whole-genome profiling of nasopharyngeal carcinoma reveals viral-host co-operation in inflammatory NF-κB activation and immune escape
2021-07-07
0.06
Artificial nighttime lighting impacts visual ecology links between flowers, pollinators and predators
2021-07-06
1
4D polycarbonates via stereolithography as scaffolds for soft tissue repair
2021-07-05
1
DHX9-dependent recruitment of BRCA1 to RNA promotes DNA end resection in homologous recombination
2021-07-05
1
Monocyte-driven atypical cytokine storm and aberrant neutrophil activation as key mediators of COVID-19 disease severity
2021-07-05
0.02
A release-and-capture mechanism generates an essential non-centrosomal microtubule array during tube budding
2021-07-02
1
Dissecting spatial heterogeneity and the immune-evasion mechanism of CTCs by single-cell RNA-seq in hepatocellular carcinoma
2021-07-02
0.06
The T cell receptor repertoire of tumor infiltrating T cells is predictive and prognostic for cancer survival
2021-07-02
0.91
Microbial short-chain fatty acids modulate CD8+ T cell responses and improve adoptive immunotherapy for cancer
2021-07-01
0.15
Serine-linked PARP1 auto-modification controls PARP inhibitor response
2021-07-01
0.69
The antiandrogen enzalutamide downregulates TMPRSS2 and reduces cellular entry of SARS-CoV-2 in human lung cells
2021-07-01
1
RAS-inhibiting biologics identify and probe druggable pockets including an SII-α3 allosteric site
2021-06-30
1
Attention-based multi-label neural networks for integrated prediction and interpretation of twelve widely occurring RNA modifications
2021-06-29
0.33
Dinosaur biodiversity declined well before the asteroid impact, influenced by ecological and environmental pressures
2021-06-29
0.25
Mouse visual cortex contains a region of enhanced spatial resolution
2021-06-29
0.14
A multi-ethnic epigenome-wide association study of leukocyte DNA methylation and blood lipids
2021-06-28
0.05
Efficient long-range conduction in cable bacteria through nickel protein wires
2021-06-28
0.03
A genetically encoded anti-CRISPR protein constrains gene drive spread and prevents population suppression
2021-06-25
0.75
Divide-and-conquer: machine-learning integrates mammalian and viral traits with network features to predict virus-mammal associations
2021-06-25
1
Impact of an accelerated melting of Greenland on malaria distribution over Africa
2021-06-25
0.14
Molecular determinants of response to PD-L1 blockade across tumor types
2021-06-25
0.04
Social transmission in the wild can reduce predation pressure on novel prey signals
2021-06-25
0.48
Storage and export of microbial biomass across the western Greenland Ice Sheet
2021-06-25
0.61
Temporal trends of SARS-CoV-2 seroprevalence during the first wave of the COVID-19 epidemic in Kenya
2021-06-25
0.18
Approximate Bayesian Computation of radiocarbon and paleoenvironmental record shows population resilience on Rapa Nui (Easter Island)
2021-06-24
0.20
Bioactivity descriptors for uncharacterized chemical compounds
2021-06-24
0.04
Contrasting responses of above- and belowground diversity to multiple components of land-use intensity
2021-06-24
0.07
Indispensable epigenetic control of thymic epithelial cell development and function by polycomb repressive complex 2
2021-06-24
0.12
Subcortical circuits mediate communication between primary sensory cortical areas in mice
2021-06-24
1
A veil of ignorance can promote fairness in a mammal society
2021-06-23
0.73
In-silico trial of intracranial flow diverters replicates and expands insights from conventional clinical trials
2021-06-23
0.79
Self-assembly of an anion receptor with metal-dependent kinase inhibition and potent in vitro anti-cancer properties
2021-06-23
1
Single cell derived mRNA signals across human kidney tumors
2021-06-23
0.73
The structure of ORC–Cdc6 on an origin DNA reveals the mechanism of ORC activation by the replication initiator Cdc6
2021-06-23
0.50
Inhibition of MRN activity by a telomere protein motif
2021-06-22
0.83
KL-VS heterozygosity is associated with lower amyloid-dependent tau accumulation and memory impairment in Alzheimer’s disease
2021-06-22
0
Oncolytic H-1 parvovirus binds to sialic acid on laminins for cell attachment and entry
2021-06-22
0.03
Preference uncertainty accounts for developmental effects on susceptibility to peer influence in adolescence
2021-06-22
0.99
Rapid evolution of bacterial mutualism in the plant rhizosphere
2021-06-22
0.13
UPF1 promotes the formation of R loops to stimulate DNA double-strand break repair
2021-06-22
1
A dynamic basal complex modulates mammalian sperm movement
2021-06-21
0.25
A gain-of-function single nucleotide variant creates a new promoter which acts as an orientation-dependent enhancer-blocker
2021-06-21
0.78
Genomic imprinting in mouse blastocysts is predominantly associated with H3K27me3
2021-06-21
0.35
Intracellular localisation of Mycobacterium tuberculosis affects efficacy of the antibiotic pyrazinamide
2021-06-21
0.67
Phenotypic manifestation of α-synuclein strains derived from Parkinson’s disease and multiple system atrophy in human dopaminergic neurons
2021-06-21
0.67
Systematic detection of functional proteoform groups from bottom-up proteomic datasets
2021-06-21
0.05
Association of social distancing and face mask use with risk of COVID-19
2021-06-18
0.24
Brain structure is linked to the association between family environment and behavioral problems in children in the ABCD study
2021-06-18
0.33
Community factors and excess mortality in first wave of the COVID-19 pandemic in England
2021-06-18
1
Hakai is required for stabilization of core components of the mA mRNA methylation machinery
2021-06-18
0.19
Serum amyloid P component is an essential element of resistance against Aspergillus fumigatus
2021-06-18
0.06
A single cell characterisation of human embryogenesis identifies pluripotency transitions and putative anterior hypoblast centre
2021-06-17
0.97
BNT162b2 vaccine uptake and effectiveness in UK healthcare workers – a single centre cohort study
2021-06-17
1
BRN2 is a non-canonical melanoma tumor-suppressor
2021-06-17
0.17
CRISPR-Associated Primase-Polymerases are implicated in prokaryotic CRISPR-Cas adaptation
2021-06-17
1
Defective folate metabolism causes germline epigenetic instability and distinguishes Hira as a phenotype inheritance biomarker
2021-06-17
1
Dendritic calcium signals in rhesus macaque motor cortex drive an optical brain-computer interface
2021-06-17
0.10
Hypoxia-induced SETX links replication stress with the unfolded protein response
2021-06-17
1
Mesoscale structure development reveals when a silkworm silk is spun
2021-06-17
0.22
Polθ inhibitors elicit BRCA-gene synthetic lethality and target PARP inhibitor resistance
2021-06-17
0.93
The long lives of primates and the ‘invariant rate of ageing’ hypothesis
2021-06-16
0.03
4D analysis of malaria parasite invasion offers insights into erythrocyte membrane remodeling and parasitophorous vacuole formation
2021-06-15
0.02
Fluctuation spectra of large random dynamical systems reveal hidden structure in ecological networks
2021-06-15
0.75
Insights into household transmission of SARS-CoV-2 from a population-based serological survey
2021-06-15
0
Intrinsic ecological dynamics drive biodiversity turnover in model metacommunities
2021-06-15
1
Learning mutational signatures and their multidimensional genomic properties with TensorSignatures
2021-06-15
0.38
Seasonality of agricultural exposure as an important predictor of seasonal yellow fever spillover in Brazil
2021-06-15
0.67
A large multiethnic GWAS meta-analysis of cataract identifies new risk loci and sex-specific effects
2021-06-14
0.09
Engineering the protein dynamics of an ancestral luciferase
2021-06-14
0.12
Distinct clinical and immunological profiles of patients with evidence of SARS-CoV-2 infection in sub-Saharan Africa
2021-06-11
0.13
Evidence of the interplay of genetics and culture in Ethiopia
2021-06-11
0.65
Experimental warming differentially affects vegetative and reproductive phenology of tundra plants
2021-06-11
0.03
Maps and metrics of insecticide-treated net access, use, and nets-per-capita in Africa from 2000-2020
2021-06-11
0.42
Non-conditioned bone marrow chimeric mouse generation using culture-based enrichment of hematopoietic stem and progenitor cells
2021-06-11
0.20
Real-time imaging of cellular forces using optical interference
2021-06-11
0.91
Reliable identification of protein-protein interactions by crosslinking mass spectrometry
2021-06-11
0.08
Structural basis of ABCF-mediated resistance to pleuromutilin, lincosamide, and streptogramin A antibiotics in Gram-positive pathogens
2021-06-11
0.14
A meta-analysis of epigenome-wide association studies in Alzheimer’s disease highlights novel differentially methylated loci across cortex
2021-06-10
0.50
A new molecular classification to drive precision treatment strategies in primary Sjögren’s syndrome
2021-06-10
0.01
Impairment of a distinct cancer-associated fibroblast population limits tumour growth and metastasis
2021-06-10
1
Single-molecule amplification-free multiplexed detection of circulating microRNA cancer biomarkers from serum
2021-06-10
1
Targeted PI3K/AKT-hyperactivation induces cell death in chronic lymphocytic leukemia
2021-06-10
0.06
Viral infiltration of pancreatic islets in patients with COVID-19
2021-06-10
0.02
Determinants of penetrance and variable expressivity in monogenic metabolic conditions across 77,184 exomes
2021-06-09
0.05
Probing the biogenesis pathway and dynamics of thylakoid membranes
2021-06-09
0.95
R2DT is a framework for predicting and visualising RNA secondary structure using templates
2021-06-09
0.33
Kin discrimination promotes horizontal gene transfer between unrelated strains in Bacillus subtilis
2021-06-08
0.10
Maternal iron deficiency perturbs embryonic cardiovascular development in mice
2021-06-08
0.85
Natural selection increases female fitness by reversing the exaggeration of a male sexually selected trait
2021-06-08
0.38
Oncogenic BRAF, unrestrained by TGFβ-receptor signalling, drives right-sided colonic tumorigenesis
2021-06-08
0.83
Two decades of neuroscience publication trends in Africa
2021-06-08
0.12
A multicentre validation study of the diagnostic value of plasma neurofilament light
2021-06-07
0.23
A recombined Sr26 and Sr61 disease resistance gene stack in wheat encodes unrelated NLR genes
2021-06-07
0.08
Assessment of protein–protein interfaces in cryo-EM derived assemblies
2021-06-07
0.88
Cis-regulatory evolution spotlights species differences in the adaptive potential of gene expression plasticity
2021-06-07
0.13
Common variants in Alzheimer’s disease and risk stratification by polygenic risk scores
2021-06-07
0.09
GATA3 induces mitochondrial biogenesis in primary human CD4+ T cells during DNA damage
2021-06-07
1
Pathogen effector recognition-dependent association of NRG1 with EDS1 and SAG101 in TNL receptor immunity
2021-06-07
0.25
SARS-CoV-2 RNAemia and proteomic trajectories inform prognostication in COVID-19 patients admitted to intensive care
2021-06-07
0.86
Suppression of tumor-associated neutrophils by lorlatinib attenuates pancreatic cancer growth and improves treatment with immune checkpoint blockade
2021-06-07
0.24
TET1-mediated DNA hydroxymethylation regulates adult remyelination in mice
2021-06-07
0.33
Ubiquitylation of MLKL at lysine 219 positively regulates necroptosis-induced tissue injury and pathogen clearance
2021-06-07
0.57
Bulk-surface coupling identifies the mechanistic connection between Min-protein patterns in vivo and in vitro
2021-06-03
0.17
Crowdsourced mapping of unexplored target space of kinase inhibitors
2021-06-03
0.01
Crystal structure of dopamine D1 receptor in complex with G protein and a non-catechol agonist
2021-06-03
0.15
Establishment of a fluorescent reporter of RNA-polymerase II activity to identify dormant cells
2021-06-03
0.25
Discovery of widespread transcription initiation at microsatellites predictable by sequence-based deep neural network
2021-06-02
0.07
Outcome after acute ischemic stroke is linked to sex-specific lesion patterns
2021-06-02
0.05
EGFR-HIF1α signaling positively regulates the differentiation of IL-9 producing T helper cells
2021-06-01
0.50
Zinc drives vasorelaxation by acting in sensory nerves, endothelium and smooth muscle
2021-06-01
0.04
Cryptic genetic variation in a heat shock protein modifies the outcome of a mutation affecting epidermal stem cell development in C. elegans
2021-05-31
1
Impact of COVID-19 outbreaks and interventions on influenza in China and the United States
2021-05-31
0.08
High proliferation and delamination during skin epidermal stratification
2021-05-28
0.14
Mitochondrial targeted meganuclease as a platform to eliminate mutant mtDNA in vivo
2021-05-28
0.11
Multimodal analysis of cell-free DNA whole-genome sequencing for pediatric cancers with low mutational burden
2021-05-28
0.11
Open fire exposure increases the risk of pregnancy loss in South Asia
2021-05-28
0.13
Retention time prediction using neural networks increases identifications in crosslinking mass spectrometry
2021-05-28
0.13
A single-cell atlas of Plasmodium falciparum transmission through the mosquito
2021-05-27
1
Chromosomal copy number heterogeneity predicts survival rates across cancers
2021-05-27
0.06
Exploring protein hotspots by optimized fragment pharmacophores
2021-05-27
0.25
Neurovascular coupling and oxygenation are decreased in hippocampus compared to neocortex because of microvascular differences
2021-05-27
1
Distinctive genetic structure and selection patterns in Plasmodium vivax from South Asia and East Africa
2021-05-26
0.53
Feature-specific reaction times reveal a semanticisation of memories over time and with repeated remembering
2021-05-26
0.67
Spatially explicit analysis identifies significant potential for bioenergy with carbon capture and storage in China
2021-05-26
0.04
Arbuscular mycorrhizal trees influence the latitudinal beta-diversity gradient of tree communities in forests worldwide
2021-05-25
0.06
Cornelia de Lange syndrome-associated mutations cause a DNA damage signalling and repair defect
2021-05-25
0.69
Endogenous memory reactivation during sleep in humans is clocked by slow oscillation-spindle complexes
2021-05-25
0.50
Evidence from oyster suggests an ancient role for Pdx in regulating insulin gene expression in animals
2021-05-25
0.52
Network isolators inhibit failure spreading in complex networks
2021-05-25
0.13
Identifying molecules as biosignatures with assembly theory and mass spectrometry
2021-05-24
0.73
Inhibition mechanism of SARS-CoV-2 main protease by ebselen and its derivatives
2021-05-24
0.42
The metabolic hormone leptin promotes the function of TFH cells and supports vaccine responses
2021-05-24
0.08
2,6-diaminopurine promotes repair of DNA lesions under prebiotic conditions
2021-05-21
0.19
A pan-African spatial assessment of human conflicts with lions and elephants
2021-05-20
0.30
Continent-wide genomic signatures of adaptation to urbanisation in a songbird across Europe
2021-05-20
0.29
Controlling COVID-19 via test-trace-quarantine
2021-05-20
0.06
Genetic architecture and lifetime dynamics of inbreeding depression in a wild mammal
2021-05-20
1
Orphan GPR116 mediates the insulin sensitizing effects of the hepatokine FNDC4 in adipose tissue
2021-05-20
0.01
Acceleration of lipid reproduction by emergence of microscopic motion
2021-05-19
0.25
Analysis of diverse eukaryotes suggests the existence of an ancestral mitochondrial apparatus derived from the bacterial type II secretion system
2021-05-19
0.10
Ecological and biogeographic drivers of biodiversity cannot be resolved using clade age-richness data
2021-05-19
0.50
Regulation of coordinated muscular relaxation in Drosophila larvae by a pattern-regulating intersegmental circuit
2021-05-19
0.33
CD8+ T cell landscape in Indigenous and non-Indigenous people restricted by influenza mortality-associated HLA-A*24:02 allomorph
2021-05-18
0.01
Global effects of land-use intensity on local pollinator biodiversity
2021-05-18
0.63
Mycobacterium tuberculosis precursor rRNA as a measure of treatment-shortening activity of drugs and regimens
2021-05-18
0.01
Neuronal genes deregulated in Cornelia de Lange Syndrome respond to removal and re-expression of cohesin
2021-05-18
0.79
Nuclear organisation and replication timing are coupled through RIF1–PP1 interaction
2021-05-18
0.42
The effect of generic market entry on antibiotic prescriptions in the United States
2021-05-18
0.11
A global resource for genomic predictions of antimicrobial resistance and surveillance of Salmonella Typhi at pathogenwatch
2021-05-17
0.84
AutoSpill is a principled framework that simplifies the analysis of multichromatic flow cytometry data
2021-05-17
0.31
Circulation of pertussis and poor protection against diphtheria among middle-aged adults in 18 European countries
2021-05-17
0.05
Heterologous vaccination regimens with self-amplifying RNA and adenoviral COVID vaccines induce robust immune responses in mice
2021-05-17
1
Nucleosome plasticity is a critical element of chromatin liquid–liquid phase separation and multivalent nucleosome interactions
2021-05-17
1
Structure of the endocytic adaptor complex reveals the basis for efficient membrane anchoring during clathrin-mediated endocytosis
2021-05-17
0.19
Cryo-EM structures of an insecticidal Bt toxin reveal its mechanism of action on the membrane
2021-05-14
0.90
Epigenome-wide association meta-analysis of DNA methylation with coffee and tea consumption
2021-05-14
0.20
Targeting human Acyl-CoA:cholesterol acyltransferase as a dual viral and T cell metabolic checkpoint
2021-05-14
0.95
The membrane-localized protein kinase MAP4K4/TOT3 regulates thermomorphogenesis
2021-05-14
0.06
Total genetic contribution assessment across the human genome
2021-05-14
0.03
Analysis of Zika virus capsid- mosquito interactome reveals pro-viral host factors critical for establishing infection
2021-05-13
0.75
Functional and diffusion MRI reveal the neurophysiological basis of neonates’ noxious-stimulus evoked brain activity
2021-05-12
1
PD-1 suppresses TCR-CD8 cooperativity during T-cell antigen recognition
2021-05-12
0.14
Ultraviolet light-induced collagen degradation inhibits melanoma invasion
2021-05-12
0.71
A minimalistic cyclic ice-binding peptide from phage display
2021-05-11
0.43
A network linking scene perception and spatial memory systems in posterior cerebral cortex
2021-05-11
0.25
Asymmetric cell division shapes naive and virtual memory T-cell immunity during ageing
2021-05-11
0.09
Conserved human effector Treg cell transcriptomic and epigenetic signature in arthritic joint inflammation
2021-05-11
0.16
Global land use changes are four times greater than previously estimated
2021-05-11
0.08
Global population structure and genotyping framework for genomic surveillance of the major dysentery pathogen, Shigella sonnei
2021-05-11
0.57
Helium in diamonds unravels over a billion years of craton metasomatism
2021-05-11
0.17
Immune cellular networks underlying recovery from influenza virus infection in acute hospitalized patients
2021-05-11
0.01
Immune evolution from preneoplasia to invasive lung adenocarcinomas and underlying molecular features
2021-05-11
0.03
Neural network aided approximation and parameter inference of non-Markovian models of gene expression
2021-05-11
0.19
The RNA landscape of the human placenta in health and disease
2021-05-11
0.82
The genomic loci of specific human tRNA genes exhibit ageing-related DNA hypermethylation
2021-05-11
0.81
The impact of stopping and starting indoor residual spraying on malaria burden in Uganda
2021-05-11
0.05
Genetic analysis in European ancestry individuals identifies 517 loci associated with liver enzymes
2021-05-10
0.10
Genoppi is an open-source software for robust and standardized integration of proteomic and genetic data
2021-05-10
0.03
LRIG1 is a gatekeeper to exit from quiescence in adult neural stem cells
2021-05-10
1
MyD88 TIR domain higher-order assembly interactions revealed by microcrystal electron diffraction and serial femtosecond crystallography
2021-05-10
0.04
Preserved structural connectivity mediates the clinical effect of thrombolysis in patients with anterior-circulation stroke
2021-05-10
0.05
Symmetry breaking of tissue mechanics in wound induced hair follicle regeneration of laboratory and spiny mice
2021-05-10
0.06
Learning with reinforcement prediction errors in a model of the Drosophila mushroom body
2021-05-07
1
Loss of function mutations in GEMIN5 cause a neurodevelopmental disorder
2021-05-07
0.04
Subtelomeric assembly of a multi-gene pathway for antimicrobial defense compounds in cereals
2021-05-07
0.50
Testing the climate intervention potential of ocean afforestation using the Great Atlantic Sargassum Belt
2021-05-07
0.08
Osteocyte transcriptome mapping identifies a molecular landscape controlling skeletal homeostasis and susceptibility to skeletal disease
2021-05-05
0.46
Regression plane concept for analysing continuous cellular processes with machine learning
2021-05-05
0.06
Size, microhabitat, and loss of larval feeding drive cranial diversification in frogs
2021-05-04
0.50
Structures of a non-ribosomal peptide synthetase condensation domain suggest the basis of substrate selectivity
2021-05-04
0.11
Molecular and clinical determinants of response and resistance to rucaparib for recurrent ovarian cancer treatment in ARIEL2 (Parts 1 and 2)
2021-05-03
0.06
Cut-like homeobox 1 (CUX1) tumor suppressor gene haploinsufficiency induces apoptosis evasion to sustain myeloid leukemia
2021-04-30
0.80
Distinct circadian mechanisms govern cardiac rhythms and susceptibility to arrhythmia
2021-04-30
0.77
Etiological, epidemiological, and clinical features of acute diarrhea in China
2021-04-29
0
Rapid evolution and host immunity drive the rise and fall of carbapenem resistance during an acute Pseudomonas aeruginosa infection
2021-04-28
0.27
FtsZ treadmilling is essential for Z-ring condensation and septal constriction initiation in Bacillus subtilis cell division
2021-04-27
0.78
Tracking the global reduction of marine traffic during the COVID-19 pandemic
2021-04-27
0.75
Genomic insights into the conservation status of the world’s last remaining Sumatran rhinoceros populations
2021-04-26
0.14
Higher gametocyte production and mosquito infectivity in chronic compared to incident Plasmodium falciparum infections
2021-04-26
0.29
A warm jet in a cold ocean
2021-04-23
0.17
CRISPR-based genome editing in primary human pancreatic islet cells
2021-04-23
0.02
Cdk5 and GSK3β inhibit fast endophilin-mediated endocytosis
2021-04-23
0.92
Estimating the effect of social inequalities on the mitigation of COVID-19 across communities in Santiago de Chile
2021-04-23
0.25
Genomic profile of advanced breast cancer in circulating tumour DNA
2021-04-23
0.83
Blood n-3 fatty acid levels and total and cause-specific mortality from 17 prospective studies
2021-04-22
0.08
Cooperation-based concept formation in male bottlenose dolphins
2021-04-22
0.21
Leveraging community mortality indicators to infer COVID-19 mortality and transmission dynamics in Damascus, Syria
2021-04-22
0.93
Photoactivatable metabolic warheads enable precise and safe ablation of target cells in vivo
2021-04-22
0.75
Activation of von Willebrand factor via mechanical unfolding of its discontinuous autoinhibitory module
2021-04-21
0.30
Distance to native climatic niche margins explains establishment success of alien mammals
2021-04-21
0.11
An integrative analysis of the age-associated multi-omic landscape across cancers
2021-04-20
1
Association of sleep duration in middle and old age with incidence of dementia
2021-04-20
0.28
Loss of α2-6 sialylation promotes the transformation of synovial fibroblasts into a pro-inflammatory phenotype in arthritis
2021-04-20
0.82
RAC1B modulates intestinal tumourigenesis via modulation of WNT and EGFR signalling pathways
2021-04-20
0.95
Energy implications of the 21st century agrarian transition
2021-04-19
0.11
Non-structural carbohydrates mediate seasonal water stress across Amazon forests
2021-04-19
0.28
Two chemically distinct root lignin barriers control solute and water balance
2021-04-19
0.47
An integrated multi-omics analysis identifies prognostic molecular subtypes of non-muscle-invasive bladder cancer
2021-04-16
0.11
Deletion of CTCF sites in the SHH locus alters enhancer–promoter interactions and leads to acheiropodia
2021-04-16
0.14
Field and classroom initiatives for portable sequence-based monitoring of dengue virus in Brazil
2021-04-16
0.01
Genetic perturbation of PU.1 binding and chromatin looping at neutrophil enhancers associates with autoimmune disease
2021-04-16
0.94
Hypothalamic Rax+ tanycytes contribute to tissue repair and tumorigenesis upon oncogene activation in mice
2021-04-16
0.09
Orally delivered MK-4482 inhibits SARS-CoV-2 replication in the Syrian hamster model
2021-04-16
0.04
Democratising deep learning for microscopy with ZeroCostDL4Mic
2021-04-15
0.30
Mortality outcomes with hydroxychloroquine and chloroquine in COVID-19 from an international collaborative meta-analysis of randomized trials
2021-04-15
0.01
Primary and secondary clarithromycin resistance in Helicobacter pylori and mathematical modeling of the role of macrolides
2021-04-15
0.04
Cell barrier function of resident peritoneal macrophages in post-operative adhesions
2021-04-14
1
Honey-collecting in prehistoric West Africa from 3500 years ago
2021-04-14
0.50
TIM4 expression by dendritic cells mediates uptake of tumor-associated antigens and anti-tumor responses
2021-04-14
0.09
A systematic approach to inserting split inteins for Boolean logic gate engineering and basal activity reduction
2021-04-13
0.57
Differences in subcortico-cortical interactions identified from connectome and microcircuit models in autism
2021-04-13
0.13
Astigmatic traction force microscopy (aTFM)
2021-04-12
0.67
Chromosome Xq23 is associated with lower atherogenic lipid concentrations and favorable cardiometabolic indices
2021-04-12
0.02
Genetic evidence for the association between COVID-19 epidemic severity and timing of non-pharmaceutical interventions
2021-04-12
1
Human anogenital monocyte-derived dendritic cells and langerin+cDC2 are major HIV target cells
2021-04-12
0.12
Increased respiratory morbidity associated with exposure to a mature volcanic plume from a large Icelandic fissure eruption
2021-04-12
0.20
Inositol treatment inhibits medulloblastoma through suppression of epigenetic-driven metabolic adaptation
2021-04-12
1
Structural plasticity of KIR2DL2 and KIR2DL3 enables altered docking geometries atop HLA-C
2021-04-12
0.10
The white matter is a pro-differentiative niche for glioblastoma
2021-04-12
0.94
Two-dimensional TIRF-SIM–traction force microscopy (2D TIRF-SIM-TFM)
2021-04-12
0.54
Adenosine integrates light and sleep signalling for the regulation of circadian timing in mice
2021-04-09
0.81
Mature Andean forests as globally important carbon sinks and future carbon refuges
2021-04-09
0.07
Physiological role for GABAA receptor desensitization in the induction of long-term potentiation at inhibitory synapses
2021-04-09
1
Varying demands for cognitive control reveals shared neural processes supporting semantic and episodic memory retrieval
2021-04-09
0.83
Defective dystrophic thymus determines degenerative changes in skeletal muscle
2021-04-08
0.08
Widespread reorganisation of pluripotent factor binding and gene regulatory interactions between human pluripotent states
2021-04-07
1
Ferroptosis response segregates small cell lung cancer (SCLC) neuroendocrine subtypes
2021-04-06
0.02
Human-lineage-specific genomic elements are associated with neurodegenerative disease and transcript usage
2021-04-06
0.25
Identifying multiple sclerosis subtypes using unsupervised machine learning and MRI data
2021-04-06
0.70
Neuroimaging evidence for a network sampling theory of individual differences in human intelligence test performance
2021-04-06
1
Normal tissue architecture determines the evolutionary course of cancer
2021-04-06
0.10
Photoactivated nanomotors via aggregation induced emission for enhanced phototherapy
2021-04-06
0.10
Proteasomal degradation of the tumour suppressor FBW7 requires branched ubiquitylation by TRIP12
2021-04-06
0.72
T cell assays differentiate clinical and subclinical SARS-CoV-2 infections from cross-reactive antiviral responses
2021-04-06
0.97
Vangl2 promotes the formation of long cytonemes to enable distant Wnt/β-catenin signaling
2021-04-06
0.71
A Hierarchical Attractor Network Model of perceptual versus intentional decision updates
2021-04-01
0.88
A KRAS-responsive long non-coding RNA controls microRNA processing
2021-04-01
0.72
Activating mutations in BRAF disrupt the hypothalamo-pituitary axis leading to hypopituitarism in mice and humans
2021-04-01
0.82
Structure of the complete, membrane-assembled COPII coat reveals a complex interaction network
2021-04-01
1
Landscapes of cellular phenotypic diversity in breast cancer xenografts and their impact on drug response
2021-03-31
0.58
Type I interferons affect the metabolic fitness of CD8 T cells from patients with systemic lupus erythematosus
2021-03-31
1
Model-based assessment of replicability for genome-wide association meta-analysis
2021-03-30
0.03
Single strain control of microbial consortia
2021-03-30
1
A haemagglutination test for rapid detection of antibodies to SARS-CoV-2
2021-03-29
0.95
Implications of the school-household network structure on SARS-CoV-2 transmission under school reopening strategies in England
2021-03-29
0.97
A conserved role for the ALS-linked splicing factor SFPQ in repression of pathogenic cryptic last exons
2021-03-26
1
DNA replication origins retain mobile licensing proteins
2021-03-26
0.13
Defective metabolic programming impairs early neuronal morphogenesis in neural cultures and an organoid model of Leigh syndrome
2021-03-26
0.01
Nonlinear machine learning pattern recognition and bacteria-metabolite multilayer network analysis of perturbed gastric microbiome
2021-03-26
0.16
Oncolytic virotherapy induced CSDE1 neo-antigenesis restricts VSV replication but can be targeted by immunotherapy
2021-03-26
0.33
A molecular timescale for eukaryote evolution with implications for the origin of red algal-derived plastids
2021-03-25
0.25
Drug ranking using machine learning systematically predicts the efficacy of anti-cancer drugs
2021-03-25
0.96
Pili allow dominant marine cyanobacteria to avoid sinking and evade predation
2021-03-25
0.73
The survival and function of IL-10-producing regulatory B cells are negatively controlled by SLAMF5
2021-03-25
0.08
Whole-genome sequencing reveals progressive versus stable myeloma precursor conditions as two distinct entities
2021-03-25
0.15
Common Era sea-level budgets along the U.S. Atlantic coast
2021-03-23
0.18
Functional annotations of three domestic animal genomes provide vital resources for comparative and agricultural research
2021-03-23
0.05
Herbaceous perennial plants with short generation time have stronger responses to climate anomalies than those with longer generation time
2021-03-23
0.17
Neurofilament light chain as a potential biomarker for monitoring neurodegeneration in X-linked adrenoleukodystrophy
2021-03-22
0.16
Reconstructing unseen transmission events to infer dengue dynamics from viral sequences
2021-03-22
0.09
The release of toxic oligomers from α-synuclein fibrils induces dysfunction in neuronal cells
2021-03-22
0.33
A human monoclonal antibody blocks malaria transmission and defines a highly conserved neutralizing epitope on gametes
2021-03-19
0.02
Clinical impact of subclonal EGFR T790M mutations in advanced-stage EGFR-mutant non-small-cell lung cancers
2021-03-19
0.62
Clonal architecture in mesothelioma is prognostic and shapes the tumour microenvironment
2021-03-19
0.93
Diel niche variation in mammals associated with expanded trait space
2021-03-19
1
Harnessing the central dogma for stringent multi-level control of gene expression
2021-03-19
0.60
Large carbon sink potential of secondary forests in the Brazilian Amazon to mitigate climate change
2021-03-19
0.42
R-loop resolution promotes co-transcriptional chromatin silencing
2021-03-19
0.50
Recruited macrophages that colonize the post-inflammatory peritoneal niche convert into functionally divergent resident cells
2021-03-19
1
Red blood cell mannoses as phagocytic ligands mediating both sickle cell anaemia and malaria resistance
2021-03-19
1
Structural and dynamic mechanisms of CBF3-guided centromeric nucleosome formation
2021-03-19
0.14
Top-down control of visual cortex by the frontal eye fields through oscillatory realignment
2021-03-19
0.50
A conserved immunogenic and vulnerable site on the coronavirus spike protein delineated by cross-reactive monoclonal antibodies
2021-03-17
0.06
Antibody-guided in vivo imaging of Aspergillus fumigatus lung infections during antifungal azole treatment
2021-03-17
0.08
α-Catenin levels determine direction of YAP/TAZ response to autophagy perturbation
2021-03-17
0.86
In situ structure and organization of the influenza C virus surface glycoprotein
2021-03-16
1
Lightning strikes as a major facilitator of prebiotic phosphorus reduction on early Earth
2021-03-16
0.78
Prospective contributions of biomass pyrolysis to China’s 2050 carbon reduction and renewable energy goals
2021-03-16
0.07
Engineering motile aqueous phase-separated droplets via liposome stabilisation
2021-03-15
1
Interactions between timing and transmissibility explain diverse flavivirus dynamics in Fiji
2021-03-15
0.42
Threats of global warming to the world’s freshwater fishes
2021-03-15
0.14
An ARF GTPase module promoting invasion and metastasis through regulating phosphoinositide metabolism
2021-03-12
1
Bi-allelic MCM10 variants associated with immune dysfunction and cardiomyopathy cause telomere shortening
2021-03-12
0.35
Circadian control of hepatitis B virus replication
2021-03-12
0.74
Cortical structural differences in major depressive disorder correlate with cell type-specific transcriptional signatures
2021-03-12
0.09
DNA methylation predicts age and provides insight into exceptional longevity of bats
2021-03-12
0.06
Discovery of fungal surface NADases predominantly present in pathogenic species
2021-03-12
0.04
Evaluating the impact of curfews and other measures on SARS-CoV-2 transmission in French Guiana
2021-03-12
0.04
Integrated cross-study datasets of genetic dependencies in cancer
2021-03-12
0.69
Long-term lymphoid progenitors independently sustain naïve T and NK cell production in humans
2021-03-12
0.82
Model-based evaluation of school- and non-school-related measures to control the COVID-19 pandemic
2021-03-12
0.07
Pervasive cooperative mutational effects on multiple catalytic enzyme traits emerge via long-range conformational dynamics
2021-03-12
0.10
A randomised controlled trial to reduce highest priority critically important antimicrobial prescription in companion animals
2021-03-11
1
Metabolomics of sebum reveals lipid dysregulation in Parkinson’s disease
2021-03-11
0.82
Structural basis for VPS34 kinase activation by Rab1 and Rab5 on membranes
2021-03-10
0.75
Versatility in acyltransferase activity completes chicoric acid biosynthesis in purple coneflower
2021-03-10
0.13
Apparent nosocomial adaptation of Enterococcus faecalis predates the modern hospital era
2021-03-09
0.25
Recovery of logged forest fragments in a human-modified tropical landscape during the 2015-16 El Niño
2021-03-09
0.46
Structural resolution of switchable states of a de novo peptide assembly
2021-03-09
0.94
Time-resolved single-cell analysis of associated mammary tumourigenesis reveals aberrant differentiation of luminal progenitors
2021-03-09
1
Predicting the public health impact of a malaria transmission-blocking vaccine
2021-03-08
0.43
Prioritizing non-coding regions based on human genomic constraint and sequence context with deep learning
2021-03-08
0.80
Spatiotemporal persistence of multiple, diverse clades and toxins of Corynebacterium diphtheriae
2021-03-08
0.34
Cytotoxic CD8+ T cells promote granzyme B-dependent adverse post-ischemic cardiac remodeling
2021-03-05
0.02
De novo design of a reversible phosphorylation-dependent switch for membrane targeting
2021-03-05
0.50
Endogenous aldehyde accumulation generates genotoxicity and exhaled biomarkers in esophageal adenocarcinoma
2021-03-05
1
Loci-specific phase separation of FET fusion oncoproteins promotes gene transcription
2021-03-05
0.18
Mitochondrial arginase-2 is essential for IL-10 metabolic reprogramming of inflammatory macrophages
2021-03-05
0.04
Perceptions of the appropriate response to norm violation in 57 societies
2021-03-05
0.03
Productive Ecosystems and the arrow of development
2021-03-05
0.22
psiCLIP reveals dynamic RNA binding by DEAH-box helicases before and after exon ligation
2021-03-05
0.97
A chromosome-level genome of Astyanax mexicanus surface fish for comparing population-specific genetic differences contributing to trait evolution
2021-03-04
0.11
Transcriptome and chromatin landscape of iNKT cells are shaped by subset differentiation and antigen exposure
2021-03-04
0.03
Somatic mutations and single-cell transcriptomes reveal the root of malignant rhabdoid tumours
2021-03-03
0.55
Meta-analysis of neural systems underlying placebo analgesia from individual participant fMRI data
2021-03-02
0.03
A molecular quantitative trait locus map for osteoarthritis
2021-02-26
0.87
Blastocyst complementation using Prdm14-deficient rats enables efficient germline transmission and generation of functional mouse spermatids in rats
2021-02-26
0.07
Combinatorial CRISPR screen identifies fitness effects of gene paralogues
2021-02-26
0.98
Mechanochemical control of epidermal stem cell divisions by B-plexins
2021-02-26
0.14
Picosecond time-resolved photon antibunching measures nanoscale exciton motion and the true number of chromophores
2021-02-26
0.09
Retroviral integrations contribute to elevated host cancer rates during germline invasion
2021-02-26
0.15
Accurate imputation of human leukocyte antigens with CookHLA
2021-02-24
0.02
Comparison of rhesus and cynomolgus macaques as an infection model for COVID-19
2021-02-24
0.99
The neutrophil antimicrobial peptide cathelicidin promotes Th17 differentiation
2021-02-24
1
A rotary mechanism for allostery in bacterial hybrid malic enzymes
2021-02-23
1
Control of oviductal fluid flow by the G-protein coupled receptor Adgrd1 is essential for murine embryo transit
2021-02-23
0.79
Flavivirus maturation leads to the formation of an occupied lipid pocket in the surface glycoproteins
2021-02-23
0.88
Polygenic hazard score is associated with prostate cancer in multi-ethnic populations
2021-02-23
0.19
Stability of synchronization in simplicial complexes
2021-02-23
0.06
Systematic functional analysis of Leishmania protein kinases identifies regulators of differentiation or survival
2021-02-23
0.83
Whole genome sequencing in the Middle Eastern Qatari population identifies genetic associations with 45 clinically relevant traits
2021-02-23
0.02
Coupled nitrification and N2 gas production as a cryptic process in oxic riverbeds
2021-02-22
0.50
Fructose reprogrammes glutamine-dependent oxidative metabolism to support LPS-induced inflammation
2021-02-22
0.81
RING domains act as both substrate and enzyme in a catalytic arrangement to drive self-anchored ubiquitination
2021-02-22
1
Calculating metalation in cells reveals CobW acquires CoII for vitamin B12 biosynthesis while related proteins prefer ZnII
2021-02-19
0.91
Cell non-autonomy amplifies disruption of neurulation by mosaic Vangl2 deletion in mice
2021-02-19
1
Characterisation of the T-cell response to Ebola virus glycoprotein amongst survivors of the 2013–16 West Africa epidemic
2021-02-19
0.60
Characterising open chromatin in chick embryos identifies cis-regulatory elements important for paraxial mesoderm formation and axis extension
2021-02-19
1
Diatom fucan polysaccharide precipitates carbon during algal blooms
2021-02-19
0.08
GWAS of peptic ulcer disease implicates Helicobacter pylori infection, other gastrointestinal disorders and depression
2021-02-19
0.13
Optimal marker gene selection for cell type discrimination in single cell analyses
2021-02-19
0.25
The evolution of critical thermal limits of life on Earth
2021-02-19
0.10
Common clonal origin of conventional T cells and induced regulatory T cells in breast cancer patients
2021-02-18
0.20
Entry of spores into intestinal epithelial cells contributes to recurrence of Clostridioides difficile infection
2021-02-18
0.18
Fecal microbiota transplantation in HIV: A pilot placebo-controlled study
2021-02-18
0.05
Inequality is rising where social network segregation interacts with urban topology
2021-02-18
0.14
POLRMT mutations impair mitochondrial transcription causing neurological disease
2021-02-18
0.15
Tumour gene expression signature in primary melanoma predicts long-term outcomes
2021-02-18
0.54
Population-specific causal disease effect sizes in functionally important regions impacted by selection
2021-02-17
0.01
Reduction in mobility and COVID-19 transmission
2021-02-17
1
Reentrant liquid condensate phase of proteins is stabilized by hydrophobic and non-ionic interactions
2021-02-17
0.68
Base-pair resolution analysis of the effect of supercoiling on DNA flexibility and major groove recognition by triplex-forming oligonucleotides
2021-02-16
1
Fast acting allosteric phosphofructokinase inhibitors block trypanosome glycolysis and cure acute African trypanosomiasis in mice
2021-02-16
0.95
Morphological bases of phytoplankton energy management and physiological responses unveiled by 3D subcellular imaging
2021-02-16
0.03
Predicting mammalian hosts in which novel coronaviruses can be generated
2021-02-16
1
Exceptionally preserved early Cambrian bilaterian developmental stages from Mongolia
2021-02-15
0.20
Genomic aberrations after short-term exposure to colibactin-producing transform primary colon epithelial cells
2021-02-12
0.06
Seasonal biological carryover dominates northern vegetation growth
2021-02-12
0.10
Diagnostic accuracy of cytology for the detection of endometrial cancer in urine and vaginal samples
2021-02-11
1
Cognitive reflection correlates with behavior on Twitter
2021-02-10
0.13
Genetic determinants of daytime napping and effects on cardiometabolic health
2021-02-10
0.04
Potential health and economic impacts of dexamethasone treatment for patients with COVID-19
2021-02-10
0.34
Replication dynamics of recombination-dependent replication forks
2021-02-10
1
SARS-CoV-2 antibody prevalence in England following the first peak of the pandemic
2021-02-10
1
The docking of synaptic vesicles on the presynaptic membrane induced by α-synuclein is modulated by lipid composition
2021-02-10
0.81
Genetic predictors of participation in optional components of UK Biobank
2021-02-09
1
Live-cell single particle tracking of PRC1 reveals a highly dynamic system with low target site occupancy
2021-02-09
1
Manganese co-limitation of phytoplankton growth and major nutrient drawdown in the Southern Ocean
2021-02-09
0.25
Particle number-based trophic transfer of gold nanomaterials in an aquatic food chain
2021-02-09
0.36
The methyltransferase METTL9 mediates pervasive 1-methylhistidine modification in mammalian proteomes
2021-02-09
0.11
Droplet printing reveals the importance of micron-scale structure for bacterial ecology
2021-02-08
0.92
Individualized interactomes for network-based precision medicine in hypertrophic cardiomyopathy with implications for other clinical pathophenotypes
2021-02-08
0.07
Listeners’ perceptions of the certainty and honesty of a speaker are associated with a common prosodic signature
2021-02-08
0.30
Cryo-EM structural analysis of FADD:Caspase-8 complexes defines the catalytic dimer architecture for co-ordinated control of cell fate
2021-02-05
1
Digital navigation of energy–structure–function maps for hydrogen-bonded porous molecular crystals
2021-02-05
0.56
Impaired eIF5A function causes a Mendelian disorder that is partially rescued in model systems by spermidine
2021-02-05
0.60
Phylogenetic analyses suggest centipede venom arsenals were repeatedly stocked by horizontal gene transfer
2021-02-05
0.50
Structure and binding properties of Pangolin-CoV spike glycoprotein inform the evolution of SARS-CoV-2
2021-02-05
0.95
The effects of releasing early results from ongoing clinical trials
2021-02-05
0.14
The genome-wide impact of trisomy 21 on DNA methylation and its implications for hematopoiesis
2021-02-05
0.33
Two mechanisms drive pronuclear migration in mouse zygotes
2021-02-05
0.21
A Sarcina bacterium linked to lethal disease in sanctuary chimpanzees in Sierra Leone
2021-02-03
0.07
A fast and efficient colocalization algorithm for identifying shared genetic risk factors across multiple traits
2021-02-03
1
Genome evolution and the emergence of pathogenicity in avian Escherichia coli
2021-02-03
0.78
Identification of 38 novel loci for systemic lupus erythematosus and genetic heterogeneity between ancestral groups
2021-02-03
0.06
The molecular basis of socially mediated phenotypic plasticity in a eusocial paper wasp
2021-02-03
0.93
The natural history of symptomatic COVID-19 during the first wave in Catalonia
2021-02-03
0.28
Asymmetric thinning of the cerebral cortex across the adult lifespan is accelerated in Alzheimer’s disease
2021-02-01
0.03
De novo DNA methyltransferase activity in colorectal cancer is directed towards H3K36me3 marked CpG islands
2021-01-29
1
Evolution of DNA methylome from precancerous lesions to invasive lung adenocarcinomas
2021-01-29
0.03
Infrared nanospectroscopy reveals the molecular interaction fingerprint of an aggregation inhibitor with single Aβ42 oligomers
2021-01-29
0.92
NeissLock provides an inducible protein anhydride for covalent targeting of endogenous proteins
2021-01-29
1
PDX1LOW MAFALOW β-cells contribute to islet function and insulin release
2021-01-29
0.66
Perception of a divergent family of phytocytokines by the Arabidopsis receptor kinase MIK2
2021-01-29
0.42
Single cell sequencing reveals endothelial plasticity with transient mesenchymal activation after myocardial infarction
2021-01-29
0.02
Stromal-driven and Amyloid β-dependent induction of neutrophil extracellular traps modulates tumor growth
2021-01-29
0.67
Structural basis for a complex I mutation that blocks pathological ROS production
2021-01-29
0.97
Automated design of synthetic microbial communities
2021-01-28
1
Direct allele introgression into pure chicken breeds using Sire Dam Surrogate (SDS) mating
2021-01-28
1
Genome-wide association study identifies risk loci for progressive chronic lymphocytic leukemia
2021-01-28
1
Genome-wide meta-analysis of muscle weakness identifies 15 susceptibility loci in older men and women
2021-01-28
0.12
Hyperpolyploidization of hepatocyte initiates preneoplastic lesion formation in the liver
2021-01-28
0.04
Innocuous pressure sensation requires A-type afferents but not functional ΡΙΕΖΟ2 channels in humans
2021-01-28
0.05
A CD8+ NK cell transcriptomic signature associated with clinical outcome in relapsing remitting multiple sclerosis
2021-01-27
0.67
Ancient proteins provide evidence of dairy consumption in eastern Africa
2021-01-27
0.04
Cryo-EM structures of the SARS-CoV-2 endoribonuclease Nsp15 reveal insight into nuclease specificity and dynamics
2021-01-27
0.05
Niche derived netrin-1 regulates hematopoietic stem cell dormancy via its receptor neogenin-1
2021-01-27
0.06
Structures of the archaerhodopsin-3 transporter reveal that disordering of internal water networks underpins receptor sensitization
2021-01-27
0.73
Subtraction-free and bisulfite-free specific sequencing of 5-methylcytosine and its oxidized derivatives at base resolution
2021-01-27
1
The contribution of X-linked coding variation to severe developmental disorders
2021-01-27
0.97
A population-based controlled experiment assessing the epidemiological impact of digital contact tracing
2021-01-26
0.10
The Bloom syndrome complex senses RPA-coated single-stranded DNA to restart stalled replication forks
2021-01-26
0.93
A conformation-selective monoclonal antibody against a small molecule-stabilised signalling-deficient form of TNF
2021-01-25
0.93
Risk variants and polygenic architecture of disruptive behavior disorders in the context of attention-deficit/hyperactivity disorder
2021-01-25
0.07
Structural insights into the disruption of TNF-TNFR1 signalling by small molecules stabilising a distorted TNF
2021-01-25
0.91
A COVID-19 vaccine candidate using SpyCatcher multimerization of the SARS-CoV-2 spike protein receptor-binding domain induces potent neutralising antibody responses
2021-01-22
0.98
Artemisinin-resistant K13 mutations rewire Plasmodium falciparum’s intra-erythrocytic metabolic program to enhance survival
2021-01-22
0.20
AutoMap is a high performance homozygosity mapping tool using next-generation sequencing data
2021-01-22
0.09
High-resolution targeted 3C interrogation of -regulatory element organization at genome-wide scale
2021-01-22
1
Life history, climate and biogeography interactively affect worldwide genetic diversity of plant and animal populations
2021-01-22
0.14
RUNX1/RUNX1T1 mediates alternative splicing and reorganises the transcriptional landscape in leukemia
2021-01-22
0.58
Oncogenic herpesvirus KSHV triggers hallmarks of alternative lengthening of telomeres
2021-01-21
0.95
Repeat DNA-PAINT suppresses background and non-specific signals in optical nanoscopy
2021-01-21
1
Sarcoma classification by DNA methylation profiling
2021-01-21
0.04
The rise of angiosperms strengthened fire feedbacks and improved the regulation of atmospheric oxygen
2021-01-21
1
Universal toxin-based selection for precise genome engineering in human cells
2021-01-21
0.18
White pupae phenotype of tephritids is caused by parallel mutations of a MFS transporter
2021-01-21
0.17
Accelerating functional gene discovery in osteoarthritis
2021-01-20
0.77
A spatially resolved brain region- and cell type-specific isoform atlas of the postnatal mouse brain
2021-01-19
0.10
Concomitant control of mechanical properties and degradation in resorbable elastomer-like materials using stereochemistry and stoichiometry for soft tissue engineering
2021-01-19
0.43
Environmental signals rather than layered ontogeny imprint the function of type 2 conventional dendritic cells in young and adult mice
2021-01-19
0.20
Intratumoral IL-12 delivery empowers CAR-T cell immunotherapy in a pre-clinical model of glioblastoma
2021-01-19
0.65
Modelling the global burden of drug-resistant tuberculosis avertable by a post-exposure vaccine
2021-01-18
0.50
PKA drives an increase in AMPA receptor unitary conductance during LTP in the hippocampus
2021-01-18
0.18
Rhythmic glucose metabolism regulates the redox circadian clockwork in human red blood cells
2021-01-15
0.50
The p63 C-terminus is essential for murine oocyte integrity
2021-01-15
0.03
Upper limits on the extent of seafloor anoxia during the PETM from uranium isotopes
2021-01-15
0.67
Serine synthesis pathway inhibition cooperates with dietary serine and glycine limitation for cancer therapy
2021-01-14
0.83
Contextual dependencies expand the re-usability of genetic inverters
2021-01-13
0.50
Dual RNA 3’-end processing of H2A.X messenger RNA maintains DNA damage repair throughout the cell cycle
2021-01-13
0.75
Genome-wide macroevolutionary signatures of key innovations in butterflies colonizing new host plants
2021-01-13
0.20
Non-invasive suppression of essential tremor via phase-locked disruption of its temporal coherence
2021-01-13
0.64
A logical network-based drug-screening platform for Alzheimer’s disease representing pathological features of human brain organoids
2021-01-12
0.02
Estimating internationally imported cases during the early COVID-19 pandemic
2021-01-12
0.08
Experimental evidence for scale-induced category convergence across populations
2021-01-12
0.33
Mathematical modeling of COVID-19 in 14.8 million individuals in Bahia, Brazil
2021-01-12
0.12
Structural basis of malaria parasite phenylalanine tRNA-synthetase inhibition by bicyclic azetidines
2021-01-12
0.08
A comprehensive re-assessment of the association between vitamin D and cancer susceptibility using Mendelian randomization
2021-01-11
0.10
BET inhibition disrupts transcription but retains enhancer-promoter contact
2021-01-11
1
BRD4-mediated repression of p53 is a target for combination therapy in AML
2021-01-11
0.87
Characterization of a new Leishmania major strain for use in a controlled human infection model
2021-01-11
0.41
Disulfide disruption reverses mucus dysfunction in allergic airway disease
2021-01-11
0.05
Graphene active sensor arrays for long-term and wireless mapping of wide frequency band epicortical brain activity
2021-01-11
0.33
LONP1 and mtHSP70 cooperate to promote mitochondrial protein folding
2021-01-11
0.13
The Arabidopsis NOT4A E3 ligase promotes PGR3 expression and regulates chloroplast translation
2021-01-11
0.58
Ultraviolet radiation drives mutations in a subset of mucosal melanomas
2021-01-11
0.38
Asynchronicity of endemic and emerging mosquito-borne disease outbreaks in the Dominican Republic
2021-01-08
0.29
Conformational and migrational dynamics of slipped-strand DNA three-way junctions containing trinucleotide repeats
2021-01-08
1
Inhibiting Mycobacterium tuberculosis CoaBC by targeting an allosteric site
2021-01-08
0.69
Potent DNA gyrase inhibitors bind asymmetrically to their target using symmetrical bifurcated halogen bonds
2021-01-08
0.60
Visualising G-quadruplex DNA dynamics in live cells by fluorescence lifetime imaging microscopy
2021-01-08
0.92
ATP synthase hexamer assemblies shape cristae of Toxoplasma mitochondria
2021-01-05
0.48
Sex-dimorphic genetic effects and novel loci for fasting glucose and insulin variability
2021-01-05
0.28
Somatostatin receptor 2 expression in nasopharyngeal cancer is induced by Epstein Barr virus infection: impact on prognosis, imaging and therapy
2021-01-05
0.41
A RAC-GEF network critical for early intestinal tumourigenesis
2021-01-04
0.76
Cardiomyocytes stimulate angiogenesis after ischemic injury in a ZEB2-dependent manner
2021-01-04
0.07
Deletion of Trim28 in committed adipocytes promotes obesity but preserves glucose tolerance
2021-01-04
0.03
Dose-dependent response to infection with SARS-CoV-2 in the ferret model and evidence of protective immunity
2021-01-04
0.96
Efficient assembly of nanopore reads via highly accurate and intact error correction
2021-01-04
0.07
Group 2i Isochrysidales produce characteristic alkenones reflecting sea ice distribution
2021-01-04
0.20
Hepatocyte-specific IL11 cis-signaling drives lipotoxicity and underlies the transition from NAFLD to NASH
2021-01-04
0.03
Insights into SusCD-mediated glycan import by a prominent gut symbiont
2021-01-04
0.75
Order and stochasticity in the folding of individual Drosophila genomes
2021-01-04
0.06
Psychological characteristics associated with COVID-19 vaccine hesitancy and resistance in Ireland and the United Kingdom
2021-01-04
0.87
Rapid parallel adaptation despite gene flow in silent crickets
2021-01-04
1
Structural basis for nuclear import selectivity of pioneer transcription factor SOX2
2021-01-04
0.13
The order and logic of CD4 versus CD8 lineage choice and differentiation in mouse thymus
2021-01-04
0.67
TBPL2/TFIIA complex establishes the maternal transcriptome through oocyte-specific promoter usage
2020-12-22
0.46
The molecular landscape of Asian breast cancers reveals clinically relevant population-specific differences
2020-12-22
0.38
Creating a regular array of metal-complexing molecules on an insulator surface at room temperature
2020-12-21
0.13
Enriched conditioning expands the regenerative ability of sensory neurons after spinal cord injury via neuronal intrinsic redox signaling
2020-12-21
0.68
A method for validating the accuracy of NMR protein structures
2020-12-18
0.67
Single-cell atlas of the first intra-mammalian developmental stage of the human parasite Schistosoma mansoni
2020-12-18
0.82
The δ subunit and NTPase HelD institute a two-pronged mechanism for RNA polymerase recycling
2020-12-18
0.05
Structure of human RNA polymerase III
2020-12-17
0.59
Genetic architecture of host proteins involved in SARS-CoV-2 infection
2020-12-16
0.65
The default network of the human brain is associated with perceived social isolation
2020-12-15
0.06
The role of polygenic risk and susceptibility genes in breast cancer over the course of life
2020-12-14
0.05
Treatment of COVID-19 with remdesivir in the absence of humoral immunity: a case report
2020-12-14
0.98
A partially self-regenerating synthetic cell
2020-12-11
0.33
A social engineering model for poverty alleviation
2020-12-11
0.67
Aberrant interaction of FUS with the U1 snRNA provides a molecular mechanism of FUS induced amyotrophic lateral sclerosis
2020-12-11
0.33
D-mannose suppresses macrophage IL-1β production
2020-12-11
0.20
Genomic epidemiology reveals transmission patterns and dynamics of SARS-CoV-2 in Aotearoa New Zealand
2020-12-11
0.02
High-resolution ex vivo NMR spectroscopy of human Z α-antitrypsin
2020-12-11
1
Open database analysis of scaling and spatio-temporal properties of power grid frequencies
2020-12-11
0.20
Quantifying and addressing the prevalence and bias of study designs in the environmental and social sciences
2020-12-11
0.11
Reconstitution of a functional human thymus by postnatal stromal progenitor cells and natural whole-organ scaffolds
2020-12-11
0.82
Iron mineral dissolution releases iron and associated organic carbon during permafrost thaw
2020-12-10
0.09
Single-cell RNA landscape of intratumoral heterogeneity and immunosuppressive microenvironment in advanced osteosarcoma
2020-12-10
0.04
Uptake of monoaromatic hydrocarbons during biodegradation by FadL channel-mediated lateral diffusion
2020-12-10
1
Varicella-zoster virus VLT-ORF63 fusion transcript induces broad viral gene expression during reactivation from neuronal latency
2020-12-10
0.11
Whole-genome sequencing analysis of the cardiometabolic proteome
2020-12-10
0.38
Condensation of Rubisco into a proto-pyrenoid in higher plant chloroplasts
2020-12-09
0.75
Male sex identified by global COVID-19 meta-analysis as a risk factor for death and ITU admission
2020-12-09
0.93
Anthropogenic modification of forests means only 40% of remaining forests have high ecosystem integrity
2020-12-08
0.02
Cerebral small vessel disease genomics and its implications across the lifespan
2020-12-08
0.09
Macrophage ATP citrate lyase deficiency stabilizes atherosclerotic plaques
2020-12-08
0.03
Nuclear numbers in syncytial muscle fibers promote size but limit the development of larger myonuclear domains
2020-12-08
0.17
Patient and public perspectives on cell and gene therapies: a systematic review
2020-12-08
1
Domestication via the commensal pathway in a fish-invertebrate mutualism
2020-12-07
0.21
Heat Shock Factor 1-dependent extracellular matrix remodeling mediates the transition from chronic intestinal inflammation to colon cancer
2020-12-07
0.10
Imaging fascicular organization of rat sciatic nerves with fast neural electrical impedance tomography
2020-12-07
1
Segment-specific optogenetic stimulation in Drosophila melanogaster with linear arrays of organic light-emitting diodes
2020-12-07
0.67
Synergistic interactions among growing stressors increase risk to an Arctic ecosystem
2020-12-07
0.16
Using antibodies to control DNA-templated chemical reactions
2020-12-07
0.33
Evidence of exposure to SARS-CoV-2 in cats and dogs from households in Italy
2020-12-04
0.29
Revealing the structures of megadalton-scale DNA complexes with nucleotide resolution
2020-12-04
0.17
State-level tracking of COVID-19 in the United States
2020-12-03
0.97
Unravelling the developmental and functional significance of an ancient Argonaute duplication
2020-12-03
0.10
Hydrogen-deuterium exchange mass spectrometry captures distinct dynamics upon substrate and inhibitor binding to a transporter
2020-12-02
0.73
In vivo biomolecular imaging of zebrafish embryos using confocal Raman spectroscopy
2020-12-02
1
Functionally impaired plasmacytoid dendritic cells and non-haematopoietic sources of type I interferon characterize human autoimmunity
2020-12-01
0.85
Reduced efficacy of HIV-1 integrase inhibitors in patients with drug resistance mutations in reverse transcriptase
2020-12-01
0.26
BETs inhibition attenuates oxidative stress and preserves muscle integrity in Duchenne muscular dystrophy
2020-11-30
0.13
Bedaquiline reprograms central metabolism to reveal glycolytic vulnerability in Mycobacterium tuberculosis
2020-11-30
0.15
Essential omega-3 fatty acids tune microglial phagocytosis of synaptic elements in the mouse developing brain
2020-11-30
0.02
Identity-by-descent detection across 487,409 British samples reveals fine scale population structure and ultra-rare variant associations
2020-11-30
0.71
MINPP1 prevents intracellular accumulation of the chelator inositol hexakisphosphate and is mutated in Pontocerebellar Hypoplasia
2020-11-30
0.06
A multivariable Mendelian randomization analysis investigating smoking and alcohol consumption in oral and oropharyngeal cancer
2020-11-27
0.65
Continuous moulting by Antarctic krill drives major pulses of carbon export in the north Scotia Sea, Southern Ocean
2020-11-27
1
Dispersal-induced instability in complex ecosystems
2020-11-27
0.50
Nutrients cause grassland biomass to outpace herbivory
2020-11-27
0.07
Transcription-dependent cohesin repositioning rewires chromatin loops in cellular senescence
2020-11-27
0.70
UMI-linked consensus sequencing enables phylogenetic analysis of directed evolution
2020-11-26
1
Genetic predisposition to hypertension is associated with preeclampsia in European and Central Asian women
2020-11-25
0.43
No evidence for increased transmissibility from recurrent mutations in SARS-CoV-2
2020-11-25
0.83
Spatial proteomics defines the content of trafficking vesicles captured by golgin tethers
2020-11-25
1
The genetic architecture of sporadic and multiple consecutive miscarriage
2020-11-25
0.30
Epigenome-wide meta-analysis of PTSD across 10 military and civilian cohorts identifies methylation changes in AHRR
2020-11-24
0.01
Horizontally acquired papGII-containing pathogenicity islands underlie the emergence of invasive uropathogenic Escherichia coli lineages
2020-11-24
0.06
Recent evolution of a TET-controlled and DPPA3/STELLA-driven pathway of passive DNA demethylation in mammals
2020-11-24
0.04
Synthetic protein-binding DNA sponge as a tool to tune gene expression and mitigate protein toxicity
2020-11-24
0.63
Common and distinct neural representations of aversive somatic and visceral stimulation in healthy individuals
2020-11-23
0.07
Epidemiology and biology of a herpesvirus in rabies endemic vampire bat populations
2020-11-23
0.78
SUCLA2 mutations cause global protein succinylation contributing to the pathomechanism of a hereditary mitochondrial disease
2020-11-23
0.04
Distinct dynamics of social motivation drive differential social behavior in laboratory rat and mouse strains
2020-11-20
0.11
Inferring the molecular and phenotypic impact of amino acid variants with MutPred2
2020-11-20
0.17
Post-lockdown SARS-CoV-2 nucleic acid screening in nearly ten million residents of Wuhan, China
2020-11-20
0.11
Regulation of cytokine signaling through direct interaction between cytokine receptors and the ATG16L1 WD40 domain
2020-11-20
0.33
Evidences for a role of two Y-specific genes in sex determination in Populus deltoides
2020-11-18
0.08
Imidazole propionate is increased in diabetes and associated with dietary patterns and altered microbial ecology
2020-11-18
0.02
Migrant birds and mammals live faster than residents
2020-11-17
0.58
PrimPol-dependent single-stranded gap formation mediates homologous recombination at bulky DNA adducts
2020-11-17
0.82
Metal-organic framework and inorganic glass composites
2020-11-16
0.64
Structural basis for tuning activity and membrane specificity of bacterial cytolysins
2020-11-16
1
Autozygosity influences cardiometabolic disease-associated traits in the AWI-Gen sub-Saharan African study
2020-11-13
0.18
CHD7 and 53BP1 regulate distinct pathways for the re-ligation of DNA double-strand breaks
2020-11-13
0.15
Characterization of neutralizing antibody with prophylactic and therapeutic efficacy against SARS-CoV-2 in rhesus monkeys
2020-11-13
0.04
Microbiota-directed fibre activates both targeted and secondary metabolic shifts in the distal gut
2020-11-13
0.13
Collider bias undermines our understanding of COVID-19 disease risk and severity
2020-11-12
0.98
Individual differences among deep neural network models
2020-11-12
0.63
Space station biomining experiment demonstrates rare earth element extraction in microgravity and Mars gravity
2020-11-10
0.19
Using the president’s tweets to understand political diversion in the age of social media
2020-11-10
0.17
Genomic landscape and clonal architecture of mouse oral squamous cell carcinomas dictate tumour ecology
2020-11-09
1
Human endogenous retroviruses form a reservoir of T cell targets in hematological cancers
2020-11-09
0.05
Tree mode of death and mortality risk factors across Amazon forests
2020-11-09
0.21
Dermal IRF4+ dendritic cells and monocytes license CD4+ T helper cells to distinct cytokine profiles
2020-11-06
0.08
Epidemiological hypothesis testing using a phylogeographic and phylodynamic framework
2020-11-06
0.12
Historical and projected future range sizes of the world’s mammals, birds, and amphibians
2020-11-06
1
The smfBox is an open-source platform for single-molecule FRET
2020-11-06
1
Tp63-expressing adult epithelial stem cells cross lineages boundaries revealing latent hairy skin competence
2020-11-06
0.09
Protrudin functions from the endoplasmic reticulum to support axon regeneration in the adult CNS
2020-11-05
0.59
Regionalized tissue fluidization is required for epithelial gap closure during insect gastrulation
2020-11-05
0.04
Perturbed structural dynamics underlie inhibition and altered efflux of the multidrug resistance pump AcrB
2020-11-04
0.69
Polyandry blocks gene drive in a wild house mouse population
2020-11-04
0.17
Type I IFN exacerbates disease in tuberculosis-susceptible mice by inducing neutrophil-mediated lung inflammation and NETosis
2020-11-04
0.68
A trimeric Rab7 GEF controls NPC1-dependent lysosomal cholesterol export
2020-11-03
0.50
The HUSH complex is a gatekeeper of type I interferon through epigenetic regulation of LINE-1s
2020-11-03
0.92
cAMP-dependent regulation of HCN4 controls the tonic entrainment process in sinoatrial node pacemaker cells
2020-11-03
0.10
Allomorphy as a mechanism of post-translational control of enzyme activity
2020-11-02
1
CFAP45 deficiency causes situs abnormalities and asthenospermia by disrupting an axonemal adenine nucleotide homeostasis module
2020-11-02
0.02
Construction of a complete set of Neisseria meningitidis mutants and its use for the phenotypic profiling of this human pathogen
2020-11-02
0.67
Gamma estimator of Jarzynski equality for recovering binding energies from noisy dynamic data sets
2020-11-02
0.33
Interpretation of morphogen gradients by a synthetic bistable circuit
2020-11-02
0.95
Parallel evolution in the emergence of highly pathogenic avian influenza A viruses
2020-11-02
1
Gene duplication drives genome expansion in a major lineage of Thaumarchaeota
2020-10-30
1
Hikarchaeia demonstrate an intermediate stage in the methanogen-to-halophile transition
2020-10-30
0.14
Role of export industries on ozone pollution and its precursors in China
2020-10-30
0.26
Intellectual disability-associated factor Zbtb11 cooperates with NRF-2/GABP to control mitochondrial function
2020-10-29
0.86
Auditory information enhances post-sensory visual evidence during rapid multisensory decision-making
2020-10-28
0.70
Dietary diversity and evolution of the earliest flying vertebrates revealed by dental microwear texture analysis
2020-10-28
1
Genome biology of the paleotetraploid perennial biomass crop
2020-10-28
0.07
Nuclear gene proximity and protein interactions shape transcript covariations in mammalian single cells
2020-10-28
0.04
Reprogramming bacterial protein organelles as a nanoreactor for hydrogen production
2020-10-28
0.69
A protein tertiary structure mimetic modulator of the Hippo signalling pathway
2020-10-27
0.14
Blood pro-resolving mediators are linked with synovial pathology and are predictive of DMARD responsiveness in rheumatoid arthritis
2020-10-27
1
Disease burden and clinical severity of the first pandemic wave of COVID-19 in Wuhan, China
2020-10-27
0.06
Globally altered epigenetic landscape and delayed osteogenic differentiation in H3.3-G34W-mutant giant cell tumor of bone
2020-10-27
0.05
Mendelian randomization study of maternal influences on birthweight and future cardiometabolic risk in the HUNT cohort
2020-10-26
0.34
Over-activation of primate subgenual cingulate cortex enhances the cardiovascular, behavioral and neural responses to threat
2020-10-26
1
The evolution of tit-for-tat in bacteria via the type VI secretion system
2020-10-26
0.29
Formation and diversification of a paradigm biosynthetic gene cluster in plants
2020-10-23
1
General destabilizing effects of eutrophication on grassland productivity at multiple spatial scales
2020-10-23
0.07
Increased power from conditional bacterial genome-wide association identifies macrolide resistance mutations in Neisseria gonorrhoeae
2020-10-23
0.29
Long-range phase synchronization of high-frequency oscillations in human cortex
2020-10-23
0.06
MEPE loss-of-function variant associates with decreased bone mineral density and increased fracture risk
2020-10-23
0.01
Targeting N-myristoylation for therapy of B-cell lymphomas
2020-10-22
0.17
A fast impedance-based antimicrobial susceptibility test
2020-10-21
0.50
Antibody-mediated disruption of the SARS-CoV-2 spike glycoprotein
2020-10-21
1
Early-onset autoimmunity associated with SOCS1 haploinsufficiency
2020-10-21
0.12
Forest production efficiency increases with growth temperature
2020-10-21
0.15
Sensitivity enhancement of homonuclear multidimensional NMR correlations for labile sites in proteins, polysaccharides, and nucleic acids
2020-10-21
0.14
Contribution of GATA6 to homeostasis of the human upper pilosebaceous unit and acne pathogenesis
2020-10-20
0.45
Prosociality predicts labor market success around the world
2020-10-20
0.50
The tomato receptor CuRe1 senses a cell wall protein to identify Cuscuta as a pathogen
2020-10-20
0.11
WNT11-FZD7-DAAM1 signalling supports tumour initiating abilities and melanoma amoeboid invasion
2020-10-20
0.76
Antibodies targeting epitopes on the cell-surface form of NS1 protect against Zika virus infection during pregnancy
2020-10-19
0.18
ATP hydrolysis by yeast Hsp104 determines protein aggregate dissolution and size in vivo
2020-10-16
0.08
Analysis of protein-DNA interactions in chromatin by UV induced cross-linking and mass spectrometry
2020-10-16
0.14
Genome-wide screens identify Toxoplasma gondii determinants of parasite fitness in IFNγ-activated murine macrophages
2020-10-16
0.11
Standardization and harmonization of distributed multi-center proteotype analysis supporting precision medicine studies
2020-10-16
0.03
Structural and functional analysis of protective antibodies targeting the threefold plateau of enterovirus 71
2020-10-16
0.45
Structure of inhibitor-bound mammalian complex I
2020-10-16
0.67
Understanding and managing new risks on the Nile with the Grand Ethiopian Renaissance Dam
2020-10-16
0.50
Whole blood immunophenotyping uncovers immature neutrophil-to-VD2 T-cell ratio as an early marker for severe COVID-19
2020-10-16
0.01
Aberrant methylation underlies insulin gene expression in human insulinoma
2020-10-15
0.10
Lyn kinase regulates egress of flaviviruses in autophagosome-derived organelles
2020-10-15
0.13
A strategy to incorporate prior knowledge into correlation network cutoff selection
2020-10-14
0.13
Evolution of DNA replication origin specification and gene silencing mechanisms
2020-10-14
0.11
Fungal oxylipins direct programmed developmental switches in filamentous fungi
2020-10-14
0.14
Pan-cancer analysis reveals TAp63-regulated oncogenic lncRNAs that promote cancer progression through AKT activation
2020-10-14
0.12
The structural variation landscape in 492 Atlantic salmon genomes
2020-10-14
0.39
Whole genome sequence analysis of pulmonary function and COPD in 19,996 multi-ethnic participants
2020-10-14
0.06
Well-being as a function of person-country fit in human values
2020-10-13
0.70
Reptile-like physiology in Early Jurassic stem-mammals
2020-10-12
0.53
Serpentine alteration as source of high dissolved silicon and elevated δ30Si values to the marine Si cycle
2020-10-12
0.20
Accommodating individual travel history and unsampled diversity in Bayesian phylogeographic inference of SARS-CoV-2
2020-10-09
0.31
Brain disconnections link structural connectivity with function and behaviour
2020-10-09
0.67
Identification of 31 loci for mammographic density phenotypes and their associations with breast cancer risk
2020-10-09
0.05
Astrocytes regulate brain extracellular pH via a neuronal activity-dependent bicarbonate shuttle
2020-10-08
0.67
Intermolecular channels direct crystal orientation in mineralized collagen
2020-10-08
0.18
Prostate cancer evolution from multilineage primary to single lineage metastases with implications for liquid biopsy
2020-10-08
0.17
Two distinct immunopathological profiles in autopsy lungs of COVID-19
2020-10-08
0.03
A fluoride-responsive genetic circuit enables in vivo biofluorination in engineered Pseudomonas putida
2020-10-07
0.33
Cryo-EM structure of the deltaretroviral intasome in complex with the PP2A regulatory subunit B56γ
2020-10-07
1
Crystallographic and electrophilic fragment screening of the SARS-CoV-2 main protease
2020-10-07
0.79
Framework for quality assessment of whole genome cancer sequences
2020-10-07
0.10
Tracing the cellular basis of islet specification in mouse pancreas
2020-10-07
0.63
Changing travel patterns in China during the early stages of the COVID-19 pandemic
2020-10-06
1
Deep phenotyping of 34,128 adult patients hospitalised with COVID-19 in an international network study
2020-10-06
0.14
Inference of person-to-person transmission of COVID-19 reveals hidden super-spreading events during the early outbreak phase
2020-10-06
0.13
Mechanism and evolution of the Zn-fingernail required for interaction of VARP with VPS29
2020-10-06
0.70
Prophage exotoxins enhance colonization fitness in epidemic scarlet fever-causing Streptococcus pyogenes
2020-10-06
0.05
Understanding high pressure molecular hydrogen with a hierarchical machine-learned potential
2020-10-06
0.89
Crop switching reduces agricultural losses from climate change in the United States by half under RCP 8.5
2020-10-05
0.50
Fetal whole heart blood flow imaging using 4D cine MRI
2020-10-05
1
Generation and trapping of a mesoderm biased state of human pluripotency
2020-10-05
1
Molecular stratification of endometrioid ovarian carcinoma predicts clinical outcome
2020-10-05
0.90
Monitoring and modeling of lymphocytic leukemia cell bioenergetics reveals decreased ATP synthesis during cell division
2020-10-05
0.03
GABA uptake transporters support dopamine release in dorsal striatum with maladaptive downregulation in a parkinsonism model
2020-10-02
1
Remote ischemic conditioning counteracts the intestinal damage of necrotizing enterocolitis by improving intestinal microcirculation
2020-10-02
0.04
SARS-CoV2-mediated suppression of NRF2-signaling reveals potent antiviral and anti-inflammatory activity of 4-octyl-itaconate and dimethyl fumarate
2020-10-02
0.05
TASOR is a pseudo-PARP that directs HUSH complex assembly and epigenetic transposon control
2020-10-02
1
Genomics of the Argentinian cholera epidemic elucidate the contrasting dynamics of epidemic and endemic Vibrio cholerae
2020-10-01
0.50
Local-scale Arctic tundra heterogeneity affects regional-scale carbon dynamics
2020-10-01
0.11
Piperacillin/tazobactam resistance in a clinical isolate of Escherichia coli due to IS26-mediated amplification of blaTEM-1B
2020-10-01
0.98
Genetic variant effects on gene expression in human pancreatic islets and their implications for T2D
2020-09-30
0.23
Development of an ObLiGaRe Doxycycline Inducible Cas9 system for pre-clinical cancer drug discovery
2020-09-29
0.25
CLR01 protects dopaminergic neurons in vitro and in mouse models of Parkinson’s disease
2020-09-28
0.48
Integrative genomics identifies a convergent molecular subtype that links epigenomic with transcriptomic differences in autism
2020-09-25
0.20
Trait phenomenological control predicts experience of mirror synaesthesia and the rubber hand illusion
2020-09-25
0.94
Combinatorial entropy behaviour leads to range selective binding in ligand-receptor interactions
2020-09-24
0.79
Phase I clinical trial repurposing all-trans retinoic acid as a stromal targeting agent for pancreatic cancer
2020-09-24
0.98
A lysozyme with altered substrate specificity facilitates prey cell exit by the periplasmic predator Bdellovibrio bacteriovorus
2020-09-23
1
Dental cell type atlas reveals stem and differentiated cell types in mouse and human teeth
2020-09-23
0.12
Genetic screens reveal a central role for heme metabolism in artemisinin susceptibility
2020-09-23
0.06
Risk prediction of late-onset Alzheimer’s disease implies an oligogenic architecture
2020-09-23
0.01
A cell-type deconvolution meta-analysis of whole blood EWAS reveals lineage-specific smoking-associated DNA methylation changes
2020-09-22
0.03
A theoretical model of Polycomb/Trithorax action unites stable epigenetic memory and dynamic regulation
2020-09-22
0.25
Genetic correlations and genome-wide associations of cortical structure in general population samples of 22,824 adults
2020-09-22
0.05
Summer warming explains widespread but not uniform greening in the Arctic tundra biome
2020-09-22
0.14
Transferring structural knowledge across cognitive maps in humans and models
2020-09-22
1
A predictable conserved DNA base composition signature defines human core DNA replication origins
2020-09-21
0.25
Regulation of cellular sterol homeostasis by the oxygen responsive noncoding RNA lincNORS
2020-09-21
0.01
Retrospective evaluation of whole exome and genome mutation calls in 746 cancer samples
2020-09-21
0.14
Single-cell sequencing reveals clonal expansions of pro-inflammatory synovial CD8 T cells expressing tissue-homing receptors in psoriatic arthritis
2020-09-21
0.95
Visual mate preference evolution during butterfly speciation is linked to neural processing genes
2020-09-21
0.19
Whole genome analysis of water buffalo and global cattle breeds highlights convergent signatures of domestication
2020-09-21
0.46
An integrated personal and population-based Egyptian genome reference
2020-09-18
0.08
The influence of soil age on ecosystem structure and function across biomes
2020-09-18
0.08
A systematic review of antibody mediated immunity to coronaviruses: kinetics, correlates of protection, and association with severity
2020-09-17
0.02
Eukaryotic cell biology is temporally coordinated to support the energetic demands of protein homeostasis
2020-09-17
0.80
Extracellular bacterial lymphatic metastasis drives Streptococcus pyogenes systemic infection
2020-09-17
1
Bacteria are important dimethylsulfoniopropionate producers in marine aphotic and high-pressure environments
2020-09-16
0.13
Systemic muscle wasting and coordinated tumour response drive tumourigenesis
2020-09-16
1
Translational pharmacology of an inhaled small molecule αvβ6 integrin inhibitor for idiopathic pulmonary fibrosis
2020-09-16
0.95
A phospho-switch controls RNF43-mediated degradation of Wnt receptors to suppress tumorigenesis
2020-09-15
0.09
Characterization and mitigation of gene expression burden in mammalian cells
2020-09-15
0.14
Entamoeba and Giardia parasites implicated as hosts of CRESS viruses
2020-09-15
0.06
Environmental variability supports chimpanzee behavioural diversity
2020-09-15
0.08
NEMF mutations that impair ribosome-associated quality control are associated with neuromuscular disease
2020-09-15
0.07
Temperate infection in a virus–host system previously known for virulent dynamics
2020-09-15
0.04
An investigation of causal relationships between prediabetes and vascular complications
2020-09-14
0.22
Effectiveness of protected areas in conserving tropical forest birds
2020-09-14
0.17
TRESK is a key regulator of nocturnal suprachiasmatic nucleus dynamics and light adaptive responses
2020-09-14
1
Diversity analysis of 80,000 wheat accessions reveals consequences and opportunities of selection footprints
2020-09-11
0.31
Global phosphorus shortage will be aggravated by soil erosion
2020-09-11
0.17
Predicting the frequencies of drug side effects
2020-09-11
0.33
DNA methylation study of Huntington’s disease and motor progression in patients and in animal models
2020-09-10
0.17
MCL-1 gains occur with high frequency in lung adenocarcinoma and can be targeted therapeutically
2020-09-10
0.08
Natural emotion vocabularies as windows on distress and well-being
2020-09-10
0.33
Resolution of R-loops by INO80 promotes DNA replication and maintains cancer cell proliferation and viability
2020-09-10
0.75
A moonlighting role for enzymes of glycolysis in the co-localization of mitochondria and chloroplasts
2020-09-09
0.11
Global patterns of the leaf economics spectrum in wetlands
2020-09-09
0.10
Segmented flow generator for serial crystallography at the European X-ray free electron laser
2020-09-09
0.02
A role for Biofoundries in rapid development and validation of automated SARS-CoV-2 clinical diagnostics
2020-09-08
1
Forest carbon sink neutralized by pervasive growth-lifespan trade-offs
2020-09-08
0.20
Integration of molecular profiles in a longitudinal wellness profiling cohort
2020-09-08
0.01
Intestinal microbiota-derived short-chain fatty acids regulation of immune cell IL-22 production and gut immunity
2020-09-08
0.06
Assembly intermediates of orthoreovirus captured in the cell
2020-09-07
0.75
Cerebrovascular risk factors impact frontoparietal network integrity and executive function in healthy ageing
2020-09-07
1
Global correlates of terrestrial and marine coverage by protected areas on islands
2020-09-07
0.21
Revised estimates of ocean-atmosphere CO2 flux are consistent with ocean carbon inventory
2020-09-04
0.88
Analysis of chromatin organization and gene expression in T cells identifies functional genes for rheumatoid arthritis
2020-09-02
0.91
Evolution of a guarded decoy protease and its receptor in solanaceous plants
2020-09-02
1
Flexible genes establish widespread bacteriophage pan-genomes in cryoconite hole ecosystems
2020-09-02
0.50
Interneuron-specific plasticity at parvalbumin and somatostatin inhibitory synapses onto CA1 pyramidal neurons shapes hippocampal output
2020-09-02
1
Rare and common vertebrates span a wide spectrum of population trends
2020-09-02
1
54 17.56
19 7.28
60 21.52
17 5.46
20 9.27
16 7.79
32 15.99
60 33.29
87 45.60
379 172.08
170 90.48
104 43.07
144 61.80
47 16.38
51 29.23
39 22.91
13 5.61
341 177.77
Physical Sciences 2357 982.85
Chemistry 1676 926.12
Earth & Environmental Sciences 1260 515.28

1 September 2020 - 31 August 2021

View the connected world of international research collaboration. Visualize collaborations by subject or region.

Collaborations between countries

Percentage of collaboration by Share

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Top 10 collaborators by Share

  • United Kingdom (UK)
  1. 824.36
    1124.53
  2. Germany (936.39)
    451.32
    485.07
  3. China (767.23)
    289.57
    477.66
  4. France (479.75)
    257.83
    221.93
  5. Italy (361.38)
    191.29
    170.09
  6. Australia (347.53)
    181.29
    166.25
  7. Switzerland (332.21)
    175.12
    157.08
  8. Netherlands (303.81)
    170.31
    133.49
  9. Spain (291.24)
    171.01
    120.23
  10. Canada (243.80)
    132.60
    111.20

Collaboration is determined by the combined fractional count (Share) of United Kingdom (UK) and the collaborating country.

Top 10 institutions from United Kingdom (UK)

Institution Count Share
1. University of Oxford 1406 433.90
2. University of Cambridge 1313 407.80
3. Imperial College London (ICL) 925 241.68
4. UCL 933 214.70
5. The University of Manchester (UoM) 522 139.09
6. The University of Edinburgh 579 136.35
7. University of Bristol (UoB) 452 118.54
8. UK Research and Innovation (UKRI) 693 93.76
9. King's College London (KCL) 432 91.80
10. Durham University 239 78.04

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