United Kingdom (UK)

1 December 2019 - 30 November 2020

Subject/journal group: All

The table to the right includes counts of all research outputs for United Kingdom (UK) published between 1 December 2019 - 30 November 2020 which are tracked by the Nature Index.

Hover over the donut graph to view the FC output for each subject. Below, the same research outputs are grouped by subject. Click on the subject to drill-down into a list of articles organized by journal, and then by title.

Note: Articles may be assigned to more than one subject area.

Count Share
8082 3835.90

Outputs by subject (FC)

Subject Count Share
Life Sciences 3596 1657.62
53 17.56
16 8.38
44 19.89
62 20.17
17 8.05
20 6.88
24 12.23
122 68.47
28 18.28
38 17.02
11 7.85
25 11.32
18 9.01
124 69.98
Natural variants modify Klebsiella pneumoniae carbapenemase (KPC) acyl-enzyme conformational dynamics to extend antibiotic resistance
2020-11-30
0.83
The cryo-EM structure of the endocytic receptor DEC-205
2020-11-30
0.03
Global reprogramming of virulence and antibiotic resistance in Pseudomonas aeruginosa by a single nucleotide polymorphism in elongation factor, fusA1
2020-11-27
1
Affinity maturation of the RLIP76 Ral binding domain to inform the design of stapled peptides targeting the Ral GTPases
2020-11-19
1
Crystal structures of γ-glutamylmethylamide synthetase provide insight into bacterial metabolism of oceanic monomethylamine
2020-11-16
0.08
Dissecting the low catalytic capability of flavin-dependent halogenases
2020-11-13
0.08
Structural basis of carnitine monooxygenase CntA substrate specificity, inhibition and inter-subunit electron transfer
2020-11-06
1
Development of a novel mammalian display system for selection of antibodies against membrane proteins
2020-10-30
1
Differential compartmental processing and phosphorylation of pathogenic human tau and native mouse tau in the Line 66 model of frontotemporal dementia
2020-10-30
0.40
Ascertaining the biochemical function of an essential pectin methylesterase in the gut microbe Bacteroides thetaiotaomicron
2020-10-23
0.75
Solvent accessibility changes in a Na+-dependent C4-dicarboxylate transporter suggest differential substrate effects in a multistep mechanism.
2020-10-21
0.75
A novel method produces native LHCII aggregates from the photosynthetic membrane revealing their role in non-photochemical quenching.
2020-10-20
0.71
Mouse Ifit1b is a cap1-RNA binding protein which inhibits mouse coronavirus translation and is regulated by complexing with Ifit1c
2020-10-19
1
Snapshots during the catalytic cycle of a histidine acid phytase reveal an induced fit structural mechanism
2020-10-14
0.88
Inhibition of the SUV4-20 H1 histone methyltransferase increases frataxin expression in Friedreich’s ataxia patient cells
2020-10-07
0.85
Genetic evidence for partial redundancy between the arginine methyltransferases CARM1 and PRMT6
2020-10-02
0.07
Structural and molecular basis for the substrate positioning mechanism of a new PL7 subfamily alginate lyase from the Arctic
2020-09-23
0.03
The cation diffusion facilitator protein MamM’s cytoplasmic domain exhibits metal-type dependent binding modes and discriminates against Mn2+
2020-09-23
0.50
Analysis of β-lactone formation by clinically observed carbapenemases informs on a novel antibiotic resistance mechanism
2020-09-22
0.63
The solution structure of the complement deregulator FHR5 reveals a compact dimer and provides new insights into CFHR5 nephropathy
2020-09-14
1
Site specific deacylation by ABHD17a controls BK channel splice variant activity
2020-09-10
1
Cholesterol sensing by CD81 is important for hepatitis C virus entry
2020-09-08
0.42
Polydisperse molecular architecture of connexin 26/30 heteromeric hemichannels revealed by AFM imaging
2020-09-04
0.14
SOX9 promotes stress-responsive transcription of VGF nerve growth factor inducible gene in renal tubular epithelial cells
2020-09-04
0.08
Dissecting the structural and functional roles of a putative metal entry site in encapsulated ferritins
2020-09-02
1
Identification of compounds that bind the centriolar protein SAS-6 and inhibit its oligomerisation
2020-09-01
0.67
Receptor-independent modulation of cAMP-dependent protein kinase and protein phosphatase signaling in cardiac myocytes by oxidizing agents
2020-08-31
0.06
Induction of UCP1 and thermogenesis by a small molecule via AKAP1/PKA modulation
2020-08-27
0.40
A post-invasion role for Chlamydia type III effector TarP in modulating the dynamics and organization of host cell focal adhesions
2020-08-25
0.38
Bioenergetic defects in muscle fibers of RYR1 mutant knock-in mice associated with malignant hyperthermia
2020-08-21
1
Alternative N-terminal regions of Drosophila myosin heavy chain II regulate communication of the purine binding loop with the essential light chain
2020-08-19
0.50
A molecular roadmap to the plant immune system
2020-08-17
1
Regulatory Effects of Post-Translational Modifications on zDHHC S-acyltransferases
2020-08-17
1
Atypical TRAV1-2- T cell receptor recognition of the antigen-presenting molecule MR1
2020-08-14
0.02
The ubiquitin-like modifier FAT10 inhibits retinal PDE6 activity and mediates its proteasomal degradation
2020-08-14
0.29
The binding mechanism of the virulence factor Streptococcus suis adhesin P subtype to globotetraosylceramide is associated with systemic disease
2020-08-12
0.04
miR-26a mediates LC-PUFA biosynthesis by targeting the Lxrα-Srebp1 pathway in the marine teleost Siganus canaliculatus
2020-08-05
0.10
Characterising the binding and function of TARP γ8-selective AMPA receptor modulators
2020-08-03
1
Adaptation induced by self-targeting in a type I-B CRISPR-Cas system
2020-07-28
0.11
Discovery of a heme-binding domain in a neuronal voltage-gated potassium channel
2020-07-28
0.84
X-ray induced photoreduction of heme metal centers rapidly induces active site perturbations in a protein-independent manner
2020-07-28
0.13
Quantitative propagation of assembled human Tau from Alzheimer's disease brain in microfluidic neuronal cultures
2020-07-22
1
Structure of a collagen VI α3 chain VWA domain array: adaptability and functional implications of myopathy causing mutations
2020-07-21
0.23
Caspr2 interacts with type 1 inositol 1,4,5-trisphosphate receptor in the developing cerebellum and regulates Purkinje cell morphology
2020-07-16
0.75
Uncovering a novel molecular mechanism for scavenging sialic acids in bacteria
2020-07-15
0.93
The role of the IT-state in D76N β2-microglobulin amyloid assembly: A crucial intermediate or an innocuous bystander?
2020-07-13
1
Cathepsin A contributes to left ventricular remodeling by degrading extracellular superoxide dismutase in mice
2020-07-09
0.16
Phosphorylation on Ser-359 of the α2 subunit in GABA type A receptors down-regulates their density at inhibitory synapses
2020-07-03
0.58
The autophagy protein Ambra1 regulates gene expression by supporting novel transcriptional complexes
2020-07-02
1
CaMKII enhances voltage-gated sodium channel Nav1.6 activity and neuronal excitability
2020-07-01
0.20
TOR complex 2 (TORC2) signaling and the ESCRT machinery cooperate in the protection of plasma membrane integrity in yeast
2020-07-01
0.17
A polysaccharide extract from the medicinal plant Maidong inhibits the IKK–NF-κB pathway and IL-1β–induced islet inflammation and increases insulin secretion
2020-06-30
0.03
The deubiquitinase USP7 uses a distinct ubiquitin-like domain to deubiquitinate NF-ĸB subunits
2020-06-25
0.63
Comparative study of the stabilities of synthetic in vitro and natural ex vivo transthyretin amyloid fibrils
2020-06-22
0.60
Crystal structures of human PAICS reveal substrate and product binding of an emerging cancer target
2020-06-22
0.08
Multimeric and monomeric photosystem II supercomplexes represent structural adaptations to low- and high-light conditions
2020-06-19
0.40
Discordance between GLP-1R gene and protein expression in mouse pancreatic islet cells
2020-06-18
0.08
Mechanical stretching changes crosslinking and glycation levels in the collagen of mouse tail tendon
2020-06-16
1
T cell receptor interactions with human leukocyte antigen govern indirect peptide selectivity for the cancer testis antigen MAGE-A4
2020-06-12
0.90
The RNA-binding protein Hfq assembles into foci-like structures in nitrogen starved Escherichia coli
2020-06-12
1
The folding and unfolding behavior of ribonuclease H on the ribosome
2020-06-11
0.40
Role of the lipid bilayer in outer membrane protein folding in Gram-negative bacteria
2020-06-04
1
Engineered anti-inflammatory peptides inspired by mapping an evasin–chemokine interaction
2020-05-29
1
Disassembly of Tau fibrils by the human Hsp70 disaggregation machinery generates small seeding-competent species
2020-05-28
0.23
Genetically encoded intrabody sensors report the interaction and trafficking of β-arrestin 1 upon activation of G-protein–coupled receptors
2020-05-21
0.17
Hypoxia drives the assembly of the multienzyme purinosome complex
2020-05-21
0.67
How repertoire data are changing antibody science
2020-05-14
1
Bifurcated binding of the OmpF receptor underpins import of the bacteriocin colicin N into Escherichia coli
2020-05-12
1
Interplay between primary familial brain calcification-associated SLC20A2 and XPR1 phosphate transporters requires inositol polyphosphates for control of cellular phosphate homeostasis
2020-05-11
0.20
Intramitochondrial proteostasis is directly coupled to α-synuclein and amyloid β1-42 pathologies
2020-05-08
1
Age-related changes in the physical properties, cross-linking, and glycation of collagen from mouse tail tendon
2020-05-07
0.71
Suramin exposure alters cellular metabolism and mitochondrial energy production in African trypanosomes
2020-04-30
0.81
Phosphorylation-dependent substrate selectivity of protein kinase B (AKT1)
2020-04-29
0.13
Targeting a critical step in fungal hexosamine biosynthesis
2020-04-27
1
The linker domain of the SNARE protein SNAP25 acts as a flexible molecular spacer that ensures efficient S-acylation
2020-04-21
1
Characterization of the structure and interactions of P450 BM3 using hybrid mass spectrometry approaches
2020-04-17
1
Interaction of the Streptomyces Wbl protein WhiD with the principal sigma factor σHrdB depends on the WhiD [4Fe-4S] cluster
2020-04-16
1
The major subunit of widespread competence pili exhibits a novel and conserved type IV pilin fold
2020-04-09
0.67
Biosynthesis of the modified tetrapyrroles--the pigments of life
2020-04-02
0.67
Iron is a ligand of SecA-like metal-binding domains in vivo
2020-04-02
0.97
Phosphoproteomic characterization of the signaling network resulting from activation of chemokine receptor CCR2
2020-04-02
0.14
Non-photopic and photopic visual cycles differentially regulate immediate, early and late-phases of cone photoreceptor-mediated vision
2020-04-01
0.11
The streptococcal multidomain fibrillar adhesin CshA has an elongated polymeric architecture
2020-03-30
1
α-Synuclein filaments from transgenic mouse and human synucleinopathy-containing brains are major seed-competent species
2020-03-24
0.67
Affinity maturation, humanization, and co-crystallization of a rabbit anti-human ROR2 monoclonal antibody for therapeutic applications
2020-03-19
0.25
Delineating an extracellular redox-sensitive module in T-type Ca2+ channels
2020-03-18
0.17
Detailed analyses of the crucial functions of Zn transporter proteins in alkaline phosphatase activation
2020-03-16
0.07
Biosynthesis of depsipeptides with a 3-hydroxybenzoate moiety and selective anticancer activities involves a chorismatase
2020-03-12
0.10
Repression of sphingosine kinase (SK)-interacting protein (SKIP) in acute myeloid leukemia diminishes SK activity and its re-expression restores SK function
2020-03-11
1
Inter-α-inhibitor heavy chain-1 has an integrin-like 3D structure mediating immune regulatory activities and matrix stabilization during ovulation
2020-03-06
0.89
MutT homologue 1 (MTH1) removes N6-methyl-dATP from the dNTP pool
2020-03-06
0.08
The transcription factor Sp1 modulates RNA polymerase III gene transcription by controlling BRF1 and GTF3C2 expression in human cells
2020-03-01
0.21
Parkinson’s disease–associated kinase LRRK2 regulates genes required for cell adhesion, polarization, and chemotaxis in activated murine macrophages
2020-02-28
1
The tetraspanin Tspan15 is an essential subunit of an ADAM10 scissor complex
2020-02-28
0.77
Kinetic parameters of human aspartate/asparagine-β-hydroxylase suggest that it has a possible function in oxygen sensing
2020-02-26
1
PYHIN1 regulates pro-inflammatory cytokine induction rather than innate immune DNA sensing in airway epithelial cells
2020-02-26
0.25
Structural insights into TAZ2 domain-mediated CBP/p300 recruitment by transactivation domain 1 of the lymphopoietic transcription factor E2A
2020-02-25
0.20
Mammalian lectin arrays for screening host-microbe interactions
2020-02-24
1
O-GlcNAcase contributes to cognitive function in Drosophila
2020-02-24
0.44
Cardiac myosin regulatory light chain kinase modulates cardiac contractility by phosphorylating both myosin regulatory light chain and troponin I
2020-02-21
0.88
The intracellular domain of homomeric glycine receptors modulates agonist efficacy
2020-02-19
0.50
Structural insights into the main S-layer unit of Deinococcus radiodurans reveal a massive protein complex with porin-like features
2020-02-18
0.05
The Shb scaffold binds the Nck adaptor protein, p120 RasGAP and Chimaerins and thereby facilitates heterotypic cell segregation by the receptor EphB2
2020-02-14
0.11
Phosphoglycerol-type wall- and lipoteichoic acids are enantiomeric polymers differentiated by the stereospecific glycerophosphodiesterase GlpQ
2020-02-11
0.29
The cortical actin network regulates avidity-dependent binding of hyaluronan by the Lymphatic Vessel Endothelial receptor LYVE-1
2020-02-07
0.93
Thrombin-derived C-terminal fragments aggregate and scavenge bacteria and their proinflammatory products
2020-02-07
0.06
In-vivo crystals reveal critical features of the interaction between CFTR and the PDZ2 domain of Na+/H+ exchange cofactor NHERF1
2020-02-02
0.50
The terminal sialic acid of stage-specific embryonic antigen-4 has a crucial role in binding to a cancer-targeting antibody
2020-01-24
0.63
Metformin lowers glucose 6-phosphate in hepatocytes by activation of glycolysis downstream of glucose phosphorylation
2020-01-23
0.67
Proteomics-based screening of the endothelial heparan sulfate interactome reveals that C-type lectin 14a (CLEC14A) is a heparin binding protein
2020-01-21
0.08
The discovery and maturation of peptide biologics targeting the small G protein Cdc42: a bioblockade for Ras-driven signalling
2020-01-20
1
Protein secondary structure determines the temporal relationship between folding and disulfide formation
2020-01-17
0.75
The basis for non-canonical ROK family function in the N-acetylmannosamine kinase from the pathogen Staphylococcus aureus
2020-01-15
0.08
A dual druggable genome-wide siRNA and compound library screening approach identifies modulators of parkin recruitment to mitochondria
2020-01-07
1
Mitochondrial residence of the apoptosis inducer BAX is more important than BAX oligomerization in promoting membrane permeabilization
2020-01-03
0.29
Disruption of the dimerization interface of the sensing domain in the dimeric heme-based oxygen sensor AfGcHK abolishes bacterial signal transduction
2019-12-30
0.10
The crystal structure of human forkhead box N1 in complex with DNA reveals the structural basis for forkhead box family specificity.
2019-12-30
0.95
Human leukocyte antigen (HLA) class II peptide flanking residues tune the immunogenicity of a human tumor-derived epitope
2019-12-27
0.93
Structure and function of Bs164 β-mannosidase from Bacteroides salyersiae the founding member of glycoside hydrolase family GH164
2019-12-22
1
The conserved C-terminus of Sss1p is required to maintain the ER permeability barrier
2019-12-17
0.09
Development of a yeast model to study the contribution of vacuolar polyphosphate metabolism to lysine polyphosphorylation.
2019-12-16
0.67
Antibody Validation for Western blot: By the User, for the User
2019-12-09
0.50
Rational engineering of 2-deoxyribose-5-phosphate aldolases for the biosynthesis of (R)-1,3-butanediol
2019-12-05
0.07
Selectivity filter instability dominates the low intrinsic activity of the TWIK-1 K2P K+ Channel
2019-12-05
0.43
31 23.23
60 24.37
25 8.72
64 40.25
42 18.65
60 22.56
189 69.53
27 7.27
20 7.15
20 8.63
781 349.74
44 14.27
25 11.47
63 22.63
22 9.23
15 5.01
26 16
26 10.59
70 35.58
81 40.79
415 186.08
166 89.50
111 40.45
154 54.42
40 14.41
47 24.73
29 13.41
20 9.76
321 184.11
Earth & Environmental Sciences 1252 531.17
Chemistry 1812 1040.02
Physical Sciences 2552 1094.78

1 December 2019 - 30 November 2020

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Collaborations between countries

Percentage of collaboration by Share

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Top 10 collaborators by Share

  • United Kingdom (UK)
  1. 831.17
    1144.34
  2. Germany (932.07)
    468.17
    463.90
  3. China (793.94)
    310.26
    483.68
  4. France (514.46)
    285.42
    229.04
  5. Australia (377.70)
    201.87
    175.83
  6. Switzerland (366.84)
    187.17
    179.66
  7. Italy (348.83)
    195.85
    152.98
  8. Netherlands (325.60)
    188.57
    137.03
  9. Spain (307.22)
    180.66
    126.57
  10. Canada (285.80)
    158.24
    127.57

Collaboration is determined by the combined fractional count (Share) of United Kingdom (UK) and the collaborating country.

Top 10 institutions from United Kingdom (UK)

Institution Count Share
1. University of Oxford 1430 458.90
2. University of Cambridge 1412 451.48
3. Imperial College London (ICL) 946 241.81
4. UCL 897 209.17
5. The University of Edinburgh 650 144.73
6. The University of Manchester (UoM) 562 143.96
7. University of Bristol (UoB) 461 135.94
8. King's College London (KCL) 422 85.63
9. University of Leeds 297 84.56
10. University of Southampton (Soton) 341 78.04

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