|
PTPN2 regulates the activation of KRAS and plays a critical role in proliferation and survival of KRAS driven cancer cells 2020-10-29 |
|
1 |
|
Transcription factor NF-κB promotes acute lung injury via microRNA-99b-mediated PRDM1 down-regulation 2020-10-27 |
|
1 |
|
Distant Coupling between RNA Editing and Alternative Splicing of the Osmosensitive Cation Channel Tmem63b 2020-10-25 |
|
1 |
|
Ascertaining the biochemical function of an essential pectin methylesterase in the gut microbe Bacteroides thetaiotaomicron 2020-10-23 |
|
0.13 |
|
Aurora B regulates PP1γ–Repo-Man interactions to maintain the chromosome condensation state 2020-10-23 |
|
1 |
|
Antibiotic binding releases autoinhibition of the TipA multidrug-resistance transcriptional regulator 2020-10-22 |
|
0.94 |
|
NSun2 promotes cell migration through methylating autotaxin mRNA 2020-10-22 |
|
1 |
|
The endosomal trafficking regulator LITAF controls the cardiac Nav1.5 channel via the ubiquitin ligase NEDD4-2 2020-10-22 |
|
0.20 |
|
Mycobacterium tuberculosis infection upregulates MFN2 expression to promote NLRP3 inflammasome formation 2020-10-16 |
|
1 |
|
Arid4b is critical for mouse embryonic stem cell differentiation towards mesoderm and endoderm, linking epigenetics to pluripotency exit 2020-10-15 |
|
0.29 |
|
Site-specific contacts enable distinct modes of TRPV1 regulation by the potassium channel Kvβ1 subunit 2020-10-15 |
|
0.89 |
|
The HRDC domain oppositely modulates the unwinding activity of E. coli RecQ helicase on duplex DNA and G-quadruplex 2020-10-14 |
|
0.94 |
|
A trade-off switch of two immunological memories in C. elegans reinfected by bacterial pathogens 2020-10-13 |
|
1 |
|
A novel stress-inducible CmtR-ESX3-Zn2+ regulatory pathway essential for survival of Mycobacterium bovis under oxidative stress 2020-10-08 |
|
1 |
|
Fibrillar α-synuclein toxicity depends on functional lysosomal 2020-10-07 |
|
0.04 |
|
Mutation of an atypical oxirane oxyanion hole improves regioselectivity of the α/β-fold epoxide hydrolase Alp1U. 2020-10-01 |
|
0.78 |
|
Molecular basis for histone H3 “K4me3-K9me3/2” methylation pattern readout by Spindlin1 2020-09-29 |
|
0.78 |
|
Calpain activation mediates microgravity-induced myocardial abnormalities in mice via p38 and ERK1/2 MAPK pathways 2020-09-28 |
|
0.58 |
|
Secretory Galectin-3 induced by glucocorticoid stress triggers stemness exhaustion of hepatic progenitor cells 2020-09-28 |
|
1 |
|
VBP1 modulates Wnt/β-catenin signaling by mediating the stability of the transcription factors TCF/LEFs 2020-09-28 |
|
1 |
|
ERAD Deficiency Promotes Mitochondrial Dysfunction and Transcriptional Rewiring in Human Hepatic Cells 2020-09-25 |
|
0.71 |
|
The amphipathic helices of Arfrp1 and Arl14 are sufficient to determine subcellular localizations 2020-09-24 |
|
1 |
|
Calnexin mediates the maturation of GPI-anchors through ER retention 2020-09-23 |
|
0.80 |
|
Structural and molecular basis for the substrate positioning mechanism of a new PL7 subfamily alginate lyase from the Arctic 2020-09-23 |
|
0.97 |
|
TET is targeted for proteasomal degradation by the PHD-pVHL pathway to reduce DNA hydroxymethylation 2020-09-22 |
|
1 |
|
TL1A inhibits atherosclerosis in apoE-deficient mice by regulating the phenotype of vascular smooth muscle cells 2020-09-22 |
|
1 |
|
Ascorbic acid enhances low-density lipoprotein receptor expression by suppressing proprotein convertase subtilisin/kexin 9 expression 2020-09-10 |
|
1 |
|
GGPP depletion initiates metaflammation through disequilibrating CYB5R3-dependent eicosanoid metabolism 2020-09-10 |
|
1 |
|
Simulations of octapeptin-outer membrane interactions reveal conformational flexibility is linked to antimicrobial potency 2020-09-10 |
|
0.42 |
|
Interactions of ferritin with scavenger receptor class A members 2020-09-09 |
|
1 |
|
A proton-coupled folate transporter mutation causing hereditary folate malabsorption locks the protein in an inward-open conformation 2020-09-06 |
|
0.14 |
|
The Central Domain of Cardiac Ryanodine Receptor Governs Channel Activation, Regulation, and Stability 2020-09-02 |
|
0.10 |
|
Orchestrated actin nucleation by the Candida albicans polarisome complex enables filamentous growth 2020-08-26 |
|
0.21 |
|
A novel HIV-1 inhibitor that blocks viral replication and rescues APOBEC3s by interrupting Vif/CBFβ interaction 2020-08-19 |
|
1 |
|
PGAP6, a GPI-specific phospholipase A2, has narrow substrate specificity against GPI-anchored proteins 2020-08-18 |
|
0.25 |
|
Increased surface charge in the protein chaperone Spy enhances its anti-aggregation activity 2020-08-17 |
|
0.50 |
|
Annexin A5 is essential for PKCθ translocation during T-cell activation 2020-08-12 |
|
1 |
|
HDAC6 regulates antibody-dependent intracellular neutralization of viruses via deacetylation of TRIM21 2020-08-12 |
|
1 |
|
miR-26a mediates LC-PUFA biosynthesis by targeting the Lxrα-Srebp1 pathway in the marine teleost Siganus canaliculatus 2020-08-05 |
|
0.80 |
|
AI26 inhibits the ADP-ribosylhydrolase ARH3 and suppresses DNA damage repair 2020-08-04 |
|
0.56 |
|
Progranulin modulates cartilage-specific gene expression via sirtuin 1-mediated deacetylation of the transcription factors SOX9 and P65 2020-08-03 |
|
1 |
|
PDLIM5 inhibits STUB1-mediated degradation of SMAD3 and promotes the migration and invasion of lung cancer cells 2020-07-31 |
|
1 |
|
Truncation of tau selectively facilitates its pathological activities 2020-07-31 |
|
0.44 |
|
The insufficiency of ATG4A in macroautophagy 2020-07-30 |
|
0.06 |
|
Complex I mutations synergize to worsen the phenotypic expression of Leber’s hereditary optic neuropathy 2020-07-28 |
|
1 |
|
Klp2 and Ase1 synergize to maintain meiotic spindle stability during metaphase I 2020-07-28 |
|
1 |
|
Survivin in breast cancer-derived exosomes activates fibroblasts by upregulating SOD1, whose feedback promotes cancer proliferation and metastasis 2020-07-24 |
|
1 |
|
The Ca2+ channel CatSper is not activated by cAMP/PKA signaling but directly affected by chemicals used to probe the action of cAMP and PKA 2020-07-23 |
|
0.15 |
|
Phase separation drives decision making in cell division 2020-07-22 |
|
0.85 |
|
A novel tumor suppressor ZBTB1 regulates tamoxifen resistance and aerobic glycolysis through suppressing HER2 expression in breast cancer 2020-07-20 |
|
0.91 |
|
Tectorigenin enhances PDX1 expression and protects pancreatic β-cells by activating ERK and reducing ER stress 2020-07-20 |
|
1 |
|
Intracellular autoactivation of TMPRSS11A, an airway epithelial transmembrane serine protease 2020-07-15 |
|
0.97 |
|
Insights into the mechanism of membrane fusion induced by the plant defense element, Plant Specific Insert 2020-07-10 |
|
0.60 |
|
Structural basis of a novel repressor, SghR, controlling Agrobacterium infection by cross-talking to plants 2020-07-10 |
|
0.18 |
|
The chaperone Hsp70 is a BH3 receptor activated by the pro-apoptotic Bim to stabilize anti-apoptotic clients 2020-07-10 |
|
1 |
|
In vivo two-photon microscopy reveals the contribution of Sox9+ cell to kidney regeneration in a mouse model with extracellular vesicle treatment 2020-07-08 |
|
1 |
|
Metabolite sensing and signaling in cancer 2020-07-07 |
|
1 |
|
Two highly related odorant receptors specifically detect α-bile acid pheromones in sea lamprey (Petromyzon marinus) 2020-07-07 |
|
0.50 |
|
Axenfeld-Rieger syndrome-associated mutants of the transcription factor FOXC1 abnormally regulate NKX2-5 in model zebrafish embryos 2020-07-06 |
|
1 |
|
A polysaccharide extract from the medicinal plant Maidong inhibits the IKK–NF-κB pathway and IL-1β–induced islet inflammation and increases insulin secretion 2020-06-30 |
|
0.94 |
|
Role of Long Noncoding RNA MEG3/MiR-378/GRB2 Axis in Neuronal Autophagy and Neurological Functional Impairment in Ischemic Stroke 2020-06-29 |
|
1 |
|
Adipose mesenchymal stem cell-derived extracellular vesicles containing microRNA-26a-5p target TLR4 and protect against diabetic nephropathy 2020-06-24 |
|
1 |
|
Runt-related transcription factor 1 is required for murine osteoblast differentiation and bone formation 2020-06-22 |
|
0.35 |
|
Disrupting phosphatase SHP2 in macrophages protects mice from high-fat diet-induced hepatic steatosis and insulin resistance by elevating IL-18 levels 2020-06-16 |
|
0.93 |
|
A single von Willebrand factor C-domain protein acts as an extracellular pattern-recognition receptor in the river prawn Macrobrachium nipponense 2020-06-12 |
|
0.83 |
|
Mediator complex subunit 16 is down-regulated in papillary thyroid cancer, leading to increased transforming growth factor-β signaling and radioiodine resistance 2020-06-12 |
|
1 |
|
Plasticity of the peroxidase AhpC links multiple substrates to diverse disulfide-reducing pathways in Shewanella oneidensis 2020-06-12 |
|
1 |
|
A unique combination of glycoside hydrolases in Streptococcus suis specifically and sequentially acts on host-derived αGal-epitope glycans 2020-06-09 |
|
0.92 |
|
Loss of the RNA-binding protein Rbm15 disrupts liver maturation in zebrafish 2020-06-09 |
|
1 |
|
A cellular endolysosome-modulating pore-forming protein from a toad is negatively regulated by its paralog under oxidizing conditions 2020-06-04 |
|
1 |
|
The Noonan syndrome-associated D61G variant of the protein tyrosine phosphatase SHP2 prevents synaptic down-scaling 2020-06-04 |
|
1 |
|
MicroRNA-223-3p promotes skeletal muscle regeneration by regulating inflammation in mice 2020-06-03 |
|
0.94 |
|
Peroxisomal oxidation of erucic acid suppresses mitochondrial fatty acid oxidation by stimulating malonyl-CoA formation in the rat liver 2020-06-03 |
|
1 |
|
Suramin and NF449 are IP5K inhibitors that disrupt inositol hexakisphosphate–mediated regulation of cullin–RING ligase and sensitize cancer cells to MLN4924/pevonedistat 2020-06-03 |
|
1 |
|
Early cleavage of preimplantation embryos is regulated by tRNAGln-TTG–derived small RNAs present in mature spermatozoa 2020-06-02 |
|
0.89 |
|
The polycomb group protein PCGF6 mediates germline gene silencing by recruiting histone-modifying proteins to target gene promoters 2020-06-01 |
|
1 |
|
A RIG-I–like receptor directs antiviral responses to a bunyavirus and is antagonized by virus-induced blockade of TRIM25-mediated ubiquitination 2020-05-29 |
|
1 |
|
Role for carbohydrate response element-binding protein (ChREBP) in high glucose-mediated repression of long noncoding RNA Tug1 2020-05-28 |
|
0.06 |
|
A specialized pore turret in the mammalian cation channel TRPV1 is responsible for distinct and species-specific heat activation thresholds 2020-05-27 |
|
0.75 |
|
Phase-separated condensate-aided enrichment of biomolecular interactions for high-throughput drug screening in test tubes 2020-05-27 |
|
1 |
|
The urea transporter UT-A1 plays a predominant role in a urea-dependent urine-concentrating mechanism 2020-05-27 |
|
0.89 |
|
Disruption of profilin1 function suppresses developmental and pathological retinal neovascularization 2020-05-22 |
|
0.11 |
|
The N-terminal domain of the non-receptor tyrosine kinase ABL confers protein instability and suppresses tumorigenesis 2020-05-21 |
|
0.67 |
|
The prohibitin-binding compound fluorizoline affects multiple components of the translational machinery and inhibits protein synthesis 2020-05-19 |
|
0.35 |
|
Tripartite-motif family protein 35-28 regulates microglia development by preventing necrotic death of microglial precursors in zebrafish 2020-05-12 |
|
1 |
|
Molecular mechanisms that regulate export of the planar cell-polarity protein Frizzled-6 out of the endoplasmic reticulum 2020-05-06 |
|
1 |
|
Cryo-electron microscopy structure of the glucagon receptor with a dual-agonist peptide 2020-05-05 |
|
0.67 |
|
Raffinose synthase enhances drought tolerance through raffinose synthesis or galactinol hydrolysis in maize and Arabidopsis plants 2020-05-04 |
|
0.75 |
|
Phosphorylation-dependent substrate selectivity of protein kinase B (AKT1) 2020-04-29 |
|
0.06 |
|
The intragenic microRNA miR199A1 in the dynamin 2 gene contributes to the pathology of X-linked centronuclear myopathy 2020-04-29 |
|
1 |
|
Acquisition of exogenous fatty acids renders apicoplast-based biosynthesis dispensable in tachyzoites of Toxoplasma 2020-04-27 |
|
0.96 |
|
Phosphorylation of the overlooked tyrosine 310 regulates the structure, aggregation, and microtubule- and lipid-binding properties of Tau 2020-04-27 |
|
0.08 |
|
The long noncoding RNA Arrl1 inhibits neurite outgrowth by functioning as a competing endogenous RNA during neuronal regeneration in rats 2020-04-26 |
|
1 |
|
Inhibition of the epigenetic suppressor EZH2 primes osteogenic differentiation mediated by BMP2 2020-04-24 |
|
0.04 |
|
S-Glutathionylation of human inducible Hsp70 reveals a regulatory mechanism involving the C-terminal α-helical lid 2020-04-24 |
|
1 |
|
Phospholipase D2 restores endothelial barrier function by promoting PTPN14-mediated VE-cadherin dephosphorylation 2020-04-23 |
|
0.12 |
|
The receptor tyrosine kinase EPHB6 regulates catecholamine exocytosis in adrenal gland chromaffin cells 2020-04-22 |
|
0.14 |
|
The acetyltransferase Eco1 elicits cohesin dimerization during S phase 2020-04-20 |
|
1 |
|
The mTOR Inhibitor Manassantin B Reveals A Crucial Role of mTORC2 Signaling in Epstein-Barr Virus Reactivation 2020-04-20 |
|
0.81 |
|
Structures of the MHC-I molecule BF2*1501 disclose the preferred presentation of an H5N1 virus-derived epitope 2020-04-17 |
|
1 |
|
O-GlcNAcylation of myosin phosphatase targeting subunit 1 (MYPT1) dictates timely disjunction of centrosomes 2020-04-15 |
|
1 |
|
Structural basis of the interplay between α-synuclein and Tau in regulating pathological amyloid aggregation 2020-04-13 |
|
1 |
|
The transcription factor ZFHX3 is crucial for the angiogenic function of hypoxia-inducible factor 1α in liver cancer cells 2020-04-10 |
|
0.91 |
|
Depletion of hepatic forkhead box O1 does not affect cholelithiasis in male and female mice 2020-04-09 |
|
0.28 |
|
Genetic ablation of the mitoribosome in the malaria parasite Plasmodium falciparum sensitizes it to antimalarials that target mitochondrial functions 2020-04-09 |
|
0.17 |
|
The USP14–NLRC5 pathway inhibits titanium particle–induced osteolysis in mice by suppressing NF-κB and PI3K/AKT activities 2020-04-09 |
|
1 |
|
Activation of JNK signaling promotes all-trans retinal-induced photoreceptor apoptosis in mice 2020-04-07 |
|
1 |
|
SUMOylation of the transcription factor ZFHX3 at Lys-2806 requires SAE1, UBC9 and PIAS2 and enhances its stability and function in cell proliferation 2020-04-05 |
|
0.92 |
|
Perturbation of phosphoglycerate kinase 1 (PGK1) only marginally affects glycolysis in cancer cells 2020-03-26 |
|
1 |
|
Pro-515 of the dynamin-like GTPase MxB contributes to HIV-1 inhibition by regulating MxB oligomerization and binding to HIV-1 capsid 2020-03-26 |
|
0.94 |
|
Genetic lineage tracing with multiple DNA recombinases: A user’s guide for conducting more precise cell fate mapping studies 2020-03-25 |
|
1 |
|
microRNA-15b contributes to depression-like behavior in mice by affecting synaptic protein levels and function in the nucleus accumbens 2020-03-24 |
|
1 |
|
Gαq splice variants mediate phototransduction, rhodopsin synthesis, and retinal integrity in Drosophila 2020-03-20 |
|
1 |
|
The FKH domain in FOXP3 mRNA frequently contains mutations in hepatocellular carcinoma that influence the subcellular localization and functions of FOXP3 2020-03-20 |
|
0.92 |
|
Delineating an extracellular redox-sensitive module in T-type Ca2+ channels 2020-03-18 |
|
0.83 |
|
A comprehensive evaluation of a typical plant telomeric G-quadruplex (G4) DNA reveals the dynamics of G4 formation, rearrangement, and unfolding 2020-03-17 |
|
1 |
|
Proline rich 11 drives F-actin assembly by recruiting the actin-related protein 2/3 complex in human non-small cell lung carcinoma 2020-03-13 |
|
1 |
|
The transcriptional regulator MEIS2 sets up the ground state for palatal osteogenesis in mice 2020-03-13 |
|
0.22 |
|
Biosynthesis of depsipeptides with a 3-hydroxybenzoate moiety and selective anticancer activities involves a chorismatase 2020-03-12 |
|
0.90 |
|
The tethering function of mitofusin2 controls osteoclast differentiation by modulating the Ca2+-NFATC1 axis 2020-03-12 |
|
0.03 |
|
The testis specific LINC component SUN3 is essential for sperm head shaping during mouse spermiogenesis 2020-03-10 |
|
0.86 |
|
The long noncoding RNA MyHC IIA/X-AS contributes to skeletal muscle myogenesis and maintains the fast fiber phenotype 2020-03-09 |
|
1 |
|
The transcription factor Sp1 modulates RNA polymerase III gene transcription by controlling BRF1 and GTF3C2 expression in human cells 2020-03-01 |
|
0.79 |
|
A recently evolved diflavin-containing monomeric nitrate reductase is responsible for highly efficient bacterial nitrate assimilation 2020-02-28 |
|
1 |
|
Structural analyses of the group A flavin-dependent monooxygenase PieE reveal a sliding FAD cofactor conformation bridging OUT and IN conformations 2020-02-28 |
|
0.20 |
|
PKA phosphorylation potentiates CFTR gating by relieving auto-inhibition on the stimulatory C terminus of the regulatory domain 2020-02-26 |
|
0.50 |
|
Paraoxonase 3 functions as a chaperone to decrease functional expression of the epithelial sodium channel 2020-02-20 |
|
0.06 |
|
The C-terminal domain of feline and bovine SAMHD1 proteins has a crucial role in lentiviral restriction 2020-02-19 |
|
1 |
|
Deficiency in the anti-apoptotic protein DJ-1 promotes intestinal epithelial cell apoptosis and aggravates inflammatory bowel disease via p53 2020-02-18 |
|
1 |
|
Vitamin D receptor targets hepatocyte nuclear factor 4α and mediates protective effects of vitamin D in nonalcoholic fatty liver disease 2020-02-12 |
|
1 |
|
Autolysosomal degradation of cytosolic chromatin fragments antagonizes oxidative stress–induced senescence 2020-02-11 |
|
1 |
|
The E3 ubiquitin ligase STUB1 attenuates cell senescence by promoting the ubiquitination and degradation of the core circadian regulator BMAL1 2020-02-10 |
|
1 |
|
The Renpenning syndrome–associated protein PQBP1 facilitates the nuclear import of splicing factor TXNL4A through the karyopherin β2 receptor 2020-02-10 |
|
1 |
|
Parthenolide inhibits ubiquitin-specific peptidase 7 (USP7), Wnt signaling, and colorectal cancer cell growth 2020-02-06 |
|
1 |
|
Histone methyltransferase G9a diminishes expression of cannabinoid CB1 receptors in primary sensory neurons in neuropathic pain 2020-02-04 |
|
0.14 |
|
"Register-shift” insulin analogs uncover constraints of proteotoxicity in protein evolution 2020-01-31 |
|
0.03 |
|
A previously identified apoptosis inhibitor iASPP confers resistance to chemotherapeutic drugs by suppressing senescence in cancer cells 2020-01-31 |
|
1 |
|
The evolutionarily conserved MAPK/Erk signaling promotes ancestral T-cell immunity in fish via c-Myc–mediated glycolysis 2020-01-29 |
|
1 |
|
The chloroplast metalloproteases VAR2 and EGY1 act synergistically to regulate chloroplast development in Arabidopsis 2020-01-24 |
|
1 |
|
Structural insights into the mechanism of c-di-GMP–bound YcgR regulating flagellar motility in Escherichia coli 2020-01-17 |
|
1 |
|
The retina and retinal pigment epithelium differ in nitrogen metabolism and are metabolically connected 2020-01-17 |
|
0.46 |
|
Loss of voltage-gated proton channel Hv1 decreases insulin secretion and leads to hyperglycemia and glucose intolerance in mice 2020-01-16 |
|
1 |
|
A novel peptide exerts potent immunosuppression by blocking the two-site interaction of NFAT with calcineurin 2020-01-15 |
|
1 |
|
Estrogen-induced FOS like 1 regulates matrix metalloproteinase expression and the motility of human endometrial/decidual stromal cells 2020-01-14 |
|
1 |
|
The transcription factor NKX2-2 regulates oligodendrocyte differentiation through domain-specific interactions with transcriptional co-repressors 2020-01-13 |
|
1 |
|
The bacterial deubiquitinase Ceg23 regulates the association of Lys-63-linked polyubiquitin molecules on the Legionella phagosome 2020-01-06 |
|
0.78 |
|
A potential target for liver cancer management, lysophosphatidic acid receptor 6 (LPAR6), is transcriptionally up-regulated by the NCOA3 coactivator 2019-12-30 |
|
1 |
|
Crystal structures and biochemical analyses of the bacterial arginine dihydrolase ArgZ suggests a “bond-rotation” catalytic mechanism 2019-12-30 |
|
1 |
|
The zebrafish NLRP3 inflammasome has functional roles in ASC-dependent interleukin-1β maturation and gasdermin E–mediated pyroptosis 2019-12-18 |
|
1 |
|
Structural insights into the catalytic mechanism of lovastatin hydrolase 2019-12-15 |
|
1 |
|
Changes in protein function underlie the disease spectrum in patients with CHIP mutations 2019-12-13 |
|
0.14 |
|
The deubiquitinase USP7 stabilizes Maf proteins to promote myeloma cell survival 2019-12-10 |
|
0.82 |
|
Overexpression of mitochondrial histidyl-tRNA synthetase restores mitochondrial dysfunction caused by a deafness-associated tRNAHis mutation 2019-12-09 |
|
0.91 |
|
Serum amyloid A exhibits pH dependent antibacterial action and contributes to host defense against Staphylococcus aureus cutaneous infection 2019-12-09 |
|
1 |
|
The ArabidopsisAtGCD3 protein is a glucosylceramidase that preferentially hydrolyzes long-acyl-chain glucosylceramides 2019-12-08 |
|
1 |
|
DLC1 SAM domain-binding peptides inhibit cancer cell growth and migration by inactivating RhoA 2019-12-05 |
|
0.14 |
|
Structural basis for shieldin complex subunit 3–mediated recruitment of the checkpoint protein REV7 during DNA double-strand break repair 2019-12-03 |
|
0.67 |
|
Enhancing subtilisin thermostability through a modified normalized B-factor analysis and loop-grafting strategy 2019-11-29 |
|
0.67 |
|
Reversible binding of the anticancer drug KXO1 (tirbanibulin) to the colchicine-binding site of β-tubulin explains KXO1's low clinical toxicity 2019-11-29 |
|
1 |
|
The molecular basis of endolytic activity of a multidomain alginate lyase from Defluviitalea phaphyphila, a representative of a new lyase family, PL39 2019-11-29 |
|
0.18 |
|
Tumor susceptibility gene 101 ameliorates endotoxin-induced cardiac dysfunction by enhancing Parkin-mediated mitophagy 2019-11-29 |
|
0.05 |
|
Triple-cell lineage tracing by a dual reporter on a single allele 2019-11-26 |
|
1 |
|
Long noncoding RNAs sustain high expression levels of exogenous octamer-binding protein 4 by sponging regulatory microRNAs during cellular reprogramming 2019-11-22 |
|
0.81 |
|
Neto proteins regulate gating of the kainate-type glutamate receptor GluK2 through two binding sites 2019-11-22 |
|
1 |
|
Staphylopine and pseudopaline dehydrogenase from bacterial pathogens catalyze reversible reactions and produce stereospecific metallophores 2019-11-22 |
|
0.50 |
|
The cysteine protease ApdS from Streptococcus suis promotes evasion of innate immune defenses by cleaving the antimicrobial peptide cathelicidin LL-37 2019-11-22 |
|
1 |
|
The synthetic cannabinoid dehydroxylcannabidiol restores the function of a major GABAA receptor isoform in a cell model of hyperekplexia 2019-11-22 |
|
1 |
|
A technique for delineating the unfolding requirements for substrate entry into retrotranslocons during endoplasmic reticulum–associated degradation 2019-11-20 |
|
1 |
|
Excessive ER-phagy mediated by the autophagy receptor FAM134B results in ER stress, the unfolded protein response, and cell death in HeLa cells 2019-11-20 |
|
0.80 |
|
Inducible Exoc7/Exo70 knockout reveals a critical role of the exocyst in insulin-regulated GLUT4 exocytosis 2019-11-18 |
|
0.11 |
|
A phenotype-directed chemical screen identifies ponalrestat as an inhibitor of the plant flavin monooxygenase YUCCA in auxin biosynthesis 2019-11-15 |
|
0.82 |
|
A thiazole-derived oridonin analogue exhibits antitumor activity by directly and allosterically inhibiting STAT3 2019-11-15 |
|
1 |
|
β-Catenin mutations as determinants of hepatoblastoma phenotypes in mice 2019-11-15 |
|
0.05 |
|
Altered allostery of the left flipper domain underlies the weak ATP-response of rat P2X5 receptors 2019-11-14 |
|
0.92 |
|
Dual-specificity tyrosine phosphorylation-regulated kinase 1A ameliorates insulin resistance in neurons by up-regulating IRS-1 expression 2019-11-13 |
|
1 |
|
Structural basis of binding of homodimers of the nuclear receptor NR4A2 to selective Nur-responsive DNA elements 2019-11-13 |
|
0.91 |
|
The MOV10 helicase restricts hepatitis B virus replication by inhibiting viral reverse transcription 2019-11-13 |
|
1 |
|
SNPs in a short basic motif in the ABC transporter ABCG2 disable its trafficking out of ER and reduce cell resistance to anticancer drugs 2019-11-12 |
|
0.52 |
|
The histone deacetylase inhibitor tubacin mitigates endothelial dysfunction by up-regulating the expression of endothelial nitric oxide synthase 2019-11-12 |
|
0.39 |
|
BMP10 preserves cardiac function through its dual-activation of SMAD-mediated and STAT3-mediated pathways 2019-11-11 |
|
0.40 |
|
Meclofenamic acid promotes cisplatin-induced acute kidney injury by inhibiting fat mass and obesity-associated protein-mediated m6A abrogation in RNA 2019-11-08 |
|
1 |
|
The R882H DNMT3A hot spot mutation stabilizes the formation of large DNMT3A oligomers with low DNA methyltransferase activity 2019-11-08 |
|
0.07 |
|
Zinc excess increases cellular demand for iron and decreases tolerance to copper in Escherichia coli 2019-11-08 |
|
0.88 |
|
High mobility group nucleosomal binding domain 2 protects against microcephaly by maintaining global chromatin accessibility during corticogenesis 2019-11-07 |
|
1 |
|
Pannexin 1 mediates ferroptosis that contributes to renal ischemia/reperfusion injury 2019-11-06 |
|
0.77 |
|
SUMOylation down-regulates rDNA transcription by repressing expression of upstream-binding factor and proto-oncogene c-Myc 2019-11-06 |
|
0.94 |
|
Lactate production is a prioritised feature of adipocyte metabolism 2019-11-05 |
|
0.03 |
|
Contribution of a mitochondrial tyrosyl-tRNA synthetase mutation to the phenotypic expression of the deafness-associated tRNASer(UCN) 7511AG mutation 2019-11-04 |
|
0.86 |
|
Hyperglycemia-induced inflamm-aging accelerates gingival senescence via NLRC4 phosphorylation 2019-11-01 |
|
1 |
