Lactation improves pancreatic β cell mass and function through serotonin production

Journal: Science Translational Medicine

Published: 2020-04-29

DOI: 10.1126/scitranslmed.aay0455

Affiliations: 12

Authors: 17

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Research Highlight

Breastfeeding can reduce risk of diabetes via serotonin

© sot/Getty

© sot/Getty

A new study reveals why breastfeeding is beneficial for the health of the mother as well as her baby, reducing her risk of developing diabetes after childbirth.

Pregnancy and childbirth can significantly disrupt a mother’s metabolism and sometimes lead to diabetes. Previous studies had found that breastfeeding reduces this risk.

Now, by comparing mice and human mothers that lactated with those that didn’t, a team led by researchers from the Korea Advanced Institute of Science and Technology (KAIST) has found the links between breastfeeding and the reduced risk of diabetes.

Breastfeeding triggers the release of the hormone serotonin. The team discovered that serotonin boosts both the number and health of beta cells in the pancreas, which are involved in the production of insulin. This in turn provides long-term protection against developing diabetes.

Supported content

  1. Science Translational Medicine 12, eaay0455 (2020). doi: 10.1126/scitranslmed.aay0455
Institutions Share
KAIST Graduate School of Medical Science and Engineering, South Korea 0.35
Department of Internal Medicine, SNU, South Korea 0.15
College of Medicine, CNU, South Korea 0.15
National Research Facilities Equipment Center (NFEC), KBSI, South Korea 0.06
Center for Convergent Research of Emerging Virus Infection, KRICT, South Korea 0.06
UAB Department of Medicine (DOM), United States of America (USA) 0.06
Department of Preventive Medicine and Public Health, AJOU, South Korea 0.06
Stanford Department of Developmental Biology, United States of America (USA) 0.03
Stanford Diabetes Research Center (SDRC), United States of America (USA) 0.03
UCSF Diabetes Center, United States of America (USA) 0.03
UCSF Department of Medicine (DOM), United States of America (USA) 0.03

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