The turning point and end of an expanding epidemic cannot be precisely forecast

Research Highlight

Pandemic progression predictable as a range of probabilities

© Brandon Colbert Photography/Moment/Getty Images

© Brandon Colbert Photography/Moment/Getty Images

The evolution of an expanding epidemic is as unpredictable as next week’s weather.

Many models have been used to try to predict the progression of the COVID-19 pandemic. However, reliable predictions proved unachievable.

A team that included researchers from the Spanish National Research Council has demonstrated that, while models for the spread of infectious diseases can provide accurate short-term predictions, their predictions inevitably grow more inaccurate with time due to small uncertainties in the initial parameters.

The team illustrated this by using a model to predict the spread of COVID-19 in Spain. It accurately replicated the disease’s spread throughout March 2020 but flopped when predicting its subsequent evolution.

Testing their model with made-up observations, the team found that small initial variations were amplified into ever greater uncertainties over time.

The researchers note that this high sensitivity to parameter values will mean that future predictions will only be meaningful within narrow time windows and in probabilistic terms, similar to weather forecasts.

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  1. PNAS 117, 26190–26196 (2020). doi: 10.1073/pnas.2007868117
Institutions Share
Grupo Interdisciplinar de Sistemas Complejos (GISC), Spain 0.44
National Centre for Biotechnology (CNB), CSIC, Spain 0.25
Comillas Pontifical University (UPCO), Spain 0.13
Charles III University of Madrid (UC3M), Spain 0.06
University of Zaragoza (Unizar), Spain 0.06
UC3M-BS Institute of Financial Big Data (IFiBiD), Spain 0.06

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