The effect of LRRK2 loss-of-function variants in humans

Journal: Nature Medicine

Published: 2020-05-27

DOI: 10.1038/s41591-020-0893-5

Affiliations: 170

Authors: 227

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Institutions Share
23andMe, Inc., United States of America (USA) 0.15
Program in Medical and Population Genetics, Broad Institute, United States of America (USA) 0.10
Data Sciences Platform (DSP), Broad Institute, United States of America (USA) 0.09
Analytic and Translational Genetics Unit (ATGU), MGH, United States of America (USA) 0.06
The Michael J. Fox Foundation for Parkinson's Research (MJFF), United States of America (USA) 0.02
Perelman School of Medicine, Penn, United States of America (USA) 0.02
Broad Institute of MIT and Harvard, United States of America (USA) 0.02
Stanley Center for Psychiatric Research, Broad Institute, United States of America (USA) 0.02
National Institute for Health and Welfare (THL), Finland 0.02
Department of Psychiatry and Behavioral Sciences, SUNY Downstate, United States of America (USA) 0.01
MRC Centre for Neuropsychiatric Genetics and Genomics (CNGG), Cardiff University, United Kingdom (UK) 0.01
Harvard Department of Medicine, United States of America (USA) 0.01
Department of Medical Epidemiology and Biostatistics (MEB), KI, Sweden 0.01
Helsinki University Central Hospital (HUCH), Finland 0.01
MRC London Institute of Medical Sciences (LMS), United Kingdom (UK) 0.01
Royal Free London NHS Foundation Trust, United Kingdom (UK) 0.01
Saint Antoine Hospital, France 0.01
Korea National Institute of Health (KNIH), South Korea 0.01
Massachusetts General Hospital (MGH), United States of America (USA) 0.01
Finnish Cardiovascular Research Center-Tampere, Tampere University, Finland 0.01
University of Mississippi Medical Center (UMMC), Ole Miss, United States of America (USA) 0.01
Faculty of Medicine, University of Helsinki, Finland 0.01
Icahn School of Medicine at Mount Sinai (ISMMS), MSHS, United States of America (USA) 0.01
Institute of Genomics, UT, Estonia 0.01
Estonian Genome Center, UT, Estonia 0.01
Department of Clinical Sciences - Malmö (DCSM), LU, Sweden 0.01
Department of Internal Medicine, SNU, South Korea 0.01
Institute of Clinical Medicine, UEF, Finland 0.01
National Institute of Medical Science and Nutrition Salvador Zubiran (INCMNSZ), Mexico 0.01
Faculty of Medicine, CUHK, China 0.01
Charles Bronfman Institute for Personalized Medicine (IPM), ISMMS, United States of America (USA) 0.01
Center for Genomic Medicine (CGM), MGH, United States of America (USA) 0.01
Brigham and Women's Hospital (BWH), United States of America (USA) 0.01
Institute for Molecular Medicine Finland (FIMM), Finland 0
Cedars-Sinai F. Widjaja Foundation Inflammatory Bowel and Immunobiology Research Institute (F. Widjaja Foundation IBIRI), United States of America (USA) 0
Institute for Genomic Medicine (IGM), CU, United States of America (USA) 0
Colorado Department of Epidemiology, United States of America (USA) 0
ICR Division of Genetics and Epidemiology, United Kingdom (UK) 0
Department of Psychiatry and Behavioral Sciences, JHU, United States of America (USA) 0
Department of Genetics, Texas Biomed, United States of America (USA) 0
University Medical Center Groningen (UMCG), RUG, Netherlands 0
Oxford Radcliffe Department of Medicine (RDM), United Kingdom (UK) 0
HUCH Laboratory of Helsinki University Hospital (HUSLAB), Finland 0
Institute of Clinical Molecular Biology (IKMB), UKSH Kiel, Germany 0
Department of Endocrinology, Metabolism and Diabetes, HUJI, Israel 0
Department of Psychiatry and Behavioral Sciences, SUNY Upstate Medical University, United States of America (USA) 0
Center for Population Health Research (CISP), INSP, Mexico 0
University of Ottawa Heart Institute (UOHI), uOttawa, Canada 0
Lund University Diabetes Centre (LUDC), LU, Sweden 0
Human Genetics Center (HGC), UTHealth, United States of America (USA) 0
Institute of Biomedicine, UEF, Finland 0
Shaare Zedek Medical Center (SZMC), Israel 0
USC Keck School of Medicine, United States of America (USA) 0
Oulu University Hospital (OUH), Finland 0
Ninewells Hospital and Medical School, United Kingdom (UK) 0
National Institute of Genomic Medicine (INMEGEN), Mexico 0
School of Medicine, Emory University, United States of America (USA) 0
McLean Hospital, United States of America (USA) 0
Department of Twin Research and Genetic Epidemiology, KCL, United Kingdom (UK) 0
Department of Psychiatry and Human Behavior, UCI, United States of America (USA) 0
Lerner Research Institute, Cleveland Clinic, United States of America (USA) 0
Wellcome Trust Genome Campus, United Kingdom (UK) 0
NIH National Human Genome Research Institute (NHGRI), United States of America (USA) 0
University Hospitals Parma Medical Center, Italy 0
Department of Cardiovascular Sciences, University of Leicester, United Kingdom (UK) 0
The Mindich Child Health and Development Institute (MCHDI), ISMMS, United States of America (USA) 0
Harvard Medical School (HMS), United States of America (USA) 0
Peninsula College of Medicine and Dentistry (PCMD), United Kingdom (UK) 0
NIHR Leicester Biomedical Research Centre, United Kingdom (UK) 0
Harvard PhD Program in Bioinformatics and Integrative Genomics (BIG), United States of America (USA) 0
Genetic Perturbation Platform, Broad Institute, United States of America (USA) 0
Hospital del Mar Medical Research Institute (IMIM), Spain 0
Biomedical Research Networking Center on Cardiovascular Diseases (CIBERCV), Spain 0
Framingham Heart Study (FHS), United States of America (USA) 0
Folkhälsan Institute of Genetics, Finland 0
National University Health System (NUHS), Singapore 0
UNC Department of Genetics, United States of America (USA) 0
Center for Non-Communicable Diseases (CNCD), Pakistan 0
UNC Department of Psychiatry, United States of America (USA) 0
TUM German Heart Centre Munich (DHM), Germany 0
Graduate School of Convergence Science and Technology (GSCST), SNU, South Korea 0
Technical University of Munich (TUM), Germany 0
VA Tennessee Valley Healthcare System, United States of America (USA) 0
Department of Medicine, VU, United States of America (USA) 0
Department of Biomedical Informatics (DBMI), VU, United States of America (USA) 0
Kuopio University Hospital (KUH), Finland 0
School of Medicine, VU, United States of America (USA) 0
Montreal Heart Institute, UdeM, Canada 0
Yale New Haven Hospital (YNHH), United States of America (USA) 0
Skåne University Hospital (SUS), Sweden 0
Department of Medicine, UdeM, Canada 0
Harvard Department of Genetics, United States of America (USA) 0
Department of Biostatistics, U-M, United States of America (USA) 0
Yale Department of Internal Medicine, United States of America (USA) 0
Institute for Genomic Medicine (IGM), UC San Diego, United States of America (USA) 0
Center for Computational and Integrative Biology (CCIB), MGH, United States of America (USA) 0
Department of Medicine, UIC, United States of America (USA) 0
Department of Pharmacology, UIC, United States of America (USA) 0
Imperial College London (ICL), United Kingdom (UK) 0
Department of Biostatistics, BU, United States of America (USA) 0
Imperial College Healthcare NHS Trust, United Kingdom (UK) 0
Ealing Hospital, LNWH, United Kingdom (UK) 0
Instituto de Investigaciones Biomédicas (IIB), UNAM, Mexico 0
Department of Psychiatry, UC San Diego, United States of America (USA) 0
Department of Genetics and Development, CU, United States of America (USA) 0
Lund University (LU), Sweden 0
Center for Statistical Genetics (CSG), U-M, United States of America (USA) 0
Department of Neurology, CU, United States of America (USA) 0
NUS Yong Loo Lin School of Medicine (YLLSoM), Singapore 0
NUS Department of Statistics and Applied Probability, Singapore 0
NUS Life Sciences Institute (LSI), Singapore 0
Duke-NUS Graduate Medical School Singapore, Singapore 0
Department of Genetics and Genomic Sciences, ISMMS, United States of America (USA) 0
Tisch Cancer Institute (TCI), ISMMS, United States of America (USA) 0
Facultat de Medicina, UVic-UCC, Spain 0
Hong Kong Institute of Diabetes and Obesity (HKIDO), CUHK, China 0
European Bioinformatics Institute (EMBL-EBI), United Kingdom (UK) 0
School of Medicine (BUSM), BU, United States of America (USA) 0
Institute for Cardiogenetics, University of Lübeck, Germany 0
DZHK Partner Site Hamburg/Kiel/Lübeck, Germany 0
Heart Center Lübeck, University of Lübeck, Germany 0
Cancer Area, Broad Institute, United States of America (USA) 0
Center for Diabetes Research, WFU, United States of America (USA) 0
Center for Genomics and Personalized Medicine Research, WFU, United States of America (USA) 0
Department of Biochemistry, WFU, United States of America (USA) 0
Boston Children's Hospital (BCH), United States of America (USA) 0
School of Public Health (SPH), BU, United States of America (USA) 0
Department of Genetics, Einstein, United States of America (USA) 0
Department of Medicine, Einstein, United States of America (USA) 0
Faculty of Natural Sciences, HU, Israel 0
Li Ka Shing Institute of Health Sciences, CUHK, China 0
Oxford Centre for Diabetes, Endocrinology and Metabolism (OCDEM), United Kingdom (UK) 0
Oxford Wellcome Trust Centre for Human Genetics, United Kingdom (UK) 0
NIHR Oxford Biomedical Research Centre (OxBRC), United Kingdom (UK) 0
Harvard Department of Pediatrics, United States of America (USA) 0
National Heart and Lung Institute (NHLI), ICL, United Kingdom (UK) 0
Department of Quantitative Health Sciences (QHS), Cleveland Clinic, United States of America (USA) 0
Department of Epidemiology and Biostatistics (EBS), ICL, United Kingdom (UK) 0
Tomsich Family Department of Cardiovascular Medicine, Cleveland Clinic, United States of America (USA) 0
Center for Basic and Translational Obesity Research, BCH, United States of America (USA) 0
Department of Cellular and Molecular Medicine (CMM), Cleveland Clinic, United States of America (USA) 0
Department of Molecular Cardiology, Cleveland Clinic, United States of America (USA) 0

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