Genome-wide association study identifies 32 novel breast cancer susceptibility loci from overall and subtype-specific analyses

Journal: Nature Genetics

Published: 2020-05-18

DOI: 10.1038/s41588-020-0609-2

Affiliations: 254

Authors: 272

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Institutions Share
NIH NCI Division of Cancer Epidemiology and Genetics (DCEG), United States of America (USA) 0.03
Centre for Cancer Genetic Epidemiology (CCGE), University of Cambridge, United Kingdom (UK) 0.03
Department of Genetics and Pathology, PMU, Poland 0.02
Netherlands Cancer Institute-Antoni van Leeuwenhoek Hospital (NKI-AVL), Netherlands 0.02
Comprehensive Cancer Center Erlangen-EMN (CCC), FAU, Germany 0.02
Cancer Institute, Erasmus MC, Netherlands 0.02
Division of Cancer Epidemiology, DKFZ, Germany 0.02
Health Innovation Manchester, United Kingdom (UK) 0.02
Helsinki University Central Hospital (HUCH), Finland 0.02
Department of Gynaecology and Obstetrics, MHH, Germany 0.02
QIMR Berghofer Department of Genetics and Computational Biology, Australia 0.01
Department of Public Health and Primary Care (DPHPC), University of Cambridge, United Kingdom (UK) 0.01
Research Group Molecular Genetics of Breast Cancer, DKFZ, Germany 0.01
Center for Integrated Oncology Aachen Bonn Köln Düsseldorf (CIO), Germany 0.01
IRCCS Istituto Nazionale dei Tumori (INT), Milan, Italy 0.01
Department of Biostatistics, JHU, United States of America (USA) 0.01
IRCCS European Institute of Oncology (IEO), Italy 0.01
Centre for Epidemiology and Biostatistics, UniMelb, Australia 0.01
Institute of Nuclear and Radiological Sciences and Technology, Energy and Safety (INRASTES), NCSR, Greece 0.01
ICR Division of Genetics and Epidemiology, United Kingdom (UK) 0.01
Bashkir State Medical University, Russia 0.01
Harvard T.H. Chan School of Public Health, United States of America (USA) 0.01
Division of Clinical Epidemiology and Aging Research, DKFZ, Germany 0.01
Department of Oncology, University of Cambridge, United Kingdom (UK) 0.01
Leiden University Medical Center (LUMC), Netherlands 0.01
Vanderbilt-Ingram Cancer Center (VICC), VU, United States of America (USA) 0.01
Centre for Research in Epidemiology and Population Health (CESP), France 0.01
Beckman Research Institute, City of Hope, United States of America (USA) 0.01
Georgetown Lombardi Comprehensive Cancer Center, United States of America (USA) 0.01
Research Centre for Genetic Engineering and Biotechnology "Georgi D. Efremov" (ICGIB), MASA, Macedonia 0.01
Bioinformatics and Computational Systems Biology of Cancer, France 0.01
Centre Hospitalier Universitaire de Québec (CHUQ), UL, Canada 0.01
Médecine Personnalisée, Pharmacogénomique, Optimisation Thérapeutique, France 0.01
Roswell Park Cancer Institute (RPCI), United States of America (USA) 0.01
Department of Molecular Genetics, NIO, Hungary 0.01
University of Kansas Medical Center (KUMC), United States of America (USA) 0.01
Ulm University Medical Center, Germany 0.01
Faculty of Medicine, Soton, United Kingdom (UK) 0.01
IRCCS Istituto Oncologico Veneto (IOV), Italy 0.01
Behavioral and Epidemiology Research Group (BERG), ACS, United States of America (USA) 0.01
School of Clinical Sciences (SCS), Monash University, Australia 0.01
Fred Hutchinson Cancer Research Center (FHCRC), United States of America (USA) 0.01
Department of Medical Epidemiology and Biostatistics (MEB), KI, Sweden 0.01
Division of Psychosocial Research and Epidemiology, NKI, Netherlands 0.01
Department of Oncology, KU Leuven, Belgium 0.01
Genetics Service, IPO, Portugal 0.01
Multidisciplinary Breast Center (MBC), UZ Leuven, Belgium 0.01
Stockholm South General Hospital, Sweden 0.01
Centro de Investigación Biomédica en Red de Cáncer (CIBERONC), Spain 0.01
Huntsman Cancer Institute at the University of Utah (HCI), Utah, United States of America (USA) 0.01
Copenhagen University Hospital (CUH), Denmark 0.01
NIH NIEHS Epidemiology Branch, United States of America (USA) 0.01
Federal State Institute of Biochemistry and Genetics, RAS, Russia 0.01
Biomedical Research Networking Center on Rare Diseases (CIBERER), Spain 0.01
Ruth and Bruce Rappaport Faculty of Medicine, IIT, Israel 0
Carmel Medical Center, Israel 0
Clalit National Israeli Cancer Control Center (NICCC), Israel 0
Department of Radiation Oncology, MHH, Germany 0
Spanish National Cancer Research Centre (CNIO), Spain 0
Moores Cancer Center, UC San Diego, United States of America (USA) 0
Cancer Epidemiology Division (CED), Cancer Council Victoria, Australia 0
UCLA Department of Obstetrics and Gynecology, United States of America (USA) 0
Department of Obstetrics and Gynecology, LMU, Germany 0
Department of Biomedical, Experimental and Clinical Sciences "Mario Serio", UNIFI, Italy 0
Zealand University Hospital, Denmark 0
Centre for Cancer Research and Cell Biology (CCRCB), QUB, United Kingdom (UK) 0
Dana-Farber Cancer Institute (DFCI), United States of America (USA) 0
Alfred Hospital, Australia 0
Stanford Cancer Institute (SCI), United States of America (USA) 0
Division of Cancer Sciences, UoM, United Kingdom (UK) 0
UCL Institute of Clinical Trials and Methodology (ICTM), United Kingdom (UK) 0
Cancer Biology and Genetics Program (CBG), MSKCC, United States of America (USA) 0
Latvian Biomedical Research and Study Centre (BMC), Latvia 0
Department of Cancer Epidemiology and Prevention, MCMCC, Poland 0
USC Keck School of Medicine, United States of America (USA) 0
Familial Cancer Centre, Australia 0
Guy's and St Thomas' NHS Foundation Trust, United Kingdom (UK) 0
ProHealth Waukesha Memorial Hospital, United States of America (USA) 0
University Clinic of Psychiatry, Macedonia 0
N. N. Petrov Research Institute of Oncology, Russia 0
NorthShore Center for Medical Genetics, United States of America (USA) 0
Saarland Cancer Registry, Germany 0
Johanniter-Krankenhaus Bonn, Germany 0
Center for Medical Genetics (CMGG), UGent, Belgium 0
Chaim Sheba Medical Center at Tel HaShomer, Israel 0
UPMC Magee-Womens Hospital, United States of America (USA) 0
UCSF Cancer Genetics and Prevention Program at Mount Zion, United States of America (USA) 0
OSU Comprehensive Cancer Center-Arthur G. James Cancer Hospital and Richard J. Solove Research Institute (OSUCCC-James), United States of America (USA) 0
Mayo Clinic College of Medicine and Science, United States of America (USA) 0
Comprehensive Cancer Center Vienna (CCC), Austria 0
Genetics and Biology of Cancers, France 0
NIH National Human Genome Research Institute (NHGRI), United States of America (USA) 0
Mailman School of Public Health, CU, United States of America (USA) 0
Odense University Hospital (OUH), Denmark 0
OSU Department Cancer Biology and Genetics, United States of America (USA) 0
Center for Women's Health, Uni Tübingen, Germany 0
Beth Israel Deaconess Medical Center (BIDMC), United States of America (USA) 0
Institute of Medical Biometry and Epidemiology, UHH, Germany 0
Helios Kliniken GmbH, Germany 0
Department of Breast Medical Oncology, MD Anderson Cancer Center, United States of America (USA) 0
Mayo Clinic Division of Epidemiology, United States of America (USA) 0
Erasmus University Medical Center (Erasmus MC), Netherlands 0
Division of Genetics, UP, South Africa 0
NIH NIEHS Biostatistics and Computational Biology Branch, United States of America (USA) 0
Lunenfeld-Tanenbaum Research Institute (LTRI), U of T, Canada 0
School of Medicine, Unisabana, Colombia 0
Institute for Prevention and Occupational Medicine of the German Social Accident Insurance (IPA), RUB, Germany 0
Masaryk Memorial Cancer Institute (MMCI), Czech Republic 0
IRCCS National Cancer Institute (INT) Bari, Italy 0
Usher Institute of Population Health Sciences and Informatics, The University of Edinburgh, United Kingdom (UK) 0
Faculty of Science and Technology, University of Westminster, United Kingdom (UK) 0
Department of Medicine, Penn, United States of America (USA) 0
Abramson Cancer Center, Penn, United States of America (USA) 0
Vall d'Hebron Institute of Oncology (VHIO), HUVH ICS, Spain 0
Fox Chase Cancer Center (FCCC), Temple University, United States of America (USA) 0
Department of Neuroscience, The University of Sheffield, United Kingdom (UK) 0
IFOM - FIRC Institute of Molecular Oncology, Italy 0
Mayo Clinic Laboratory Medicine and Pathology, United States of America (USA) 0
Heidelberg University Hospital at Medical Faculty Heidelberg, Uni Heidelberg, Germany 0
Clinical Genetics Group, KI, Sweden 0
Yale School of Public Health, United States of America (USA) 0
Abel Salazar Biomedical Sciences Institute (ICBAS), UP, Portugal 0
Städtisches Klinikum Karlsruhe gGmbH, Germany 0
Galicia Sur Health Research Institute (IISGS), Spain 0
General University Hospital of Larissa, Greece 0
University Hospital of Pisa, UNIPI, Italy 0
Health Research Institute of San Carlos (IdISSC), Spain 0
Manchester University NHS Foundation Trust (MFT), United Kingdom (UK) 0
Faculty of Medicine, UKIM, Macedonia 0
Independent Laboratory of Molecular Biology and Genetic Diagnostics, PMU, Poland 0
National Center for Tumor Diseases (NCT) Heidelberg, Germany 0
Institute of Environmental Medicine (IMM), KI, Sweden 0
Department of Surgical Sciences, UU, Sweden 0
Dr. Margarete Fischer-Bosch-Institute of Clinical Pharmacology (IKP), Germany 0
German Consortium of Translational Cancer Research (DKTK), Germany 0
Galician Health Service (SERGAS), Spain 0
USC University Hospital Complex (CHUS), Spain 0
USC Health Research Institute of Santiago de Compostela (IDIS), Spain 0
Bellvitge Biomedical Research Institute (IDIBELL), Spain 0
Division of Oncology and Pathology, LU, Sweden 0
Skåne University Hospital in Lund, SUS, Sweden 0
Guy's Hospital, Guy's and St Thomas' NHS Foundation Trust, United Kingdom (UK) 0
Division of Cancer Studies, KCL, United Kingdom (UK) 0
School of Population and Public Health (SPPH), UBC, Canada 0
Division of Molecular Genetic Epidemiology, DKFZ, Germany 0
Department of Internal Medicine, Utah, United States of America (USA) 0
University Cancer Center Hamburg (UCCH), UHH, Germany 0
Department of Pediatrics, CU, United States of America (USA) 0
Department of Medicine, CU, United States of America (USA) 0
Hospital Universitario Puerta de Hierro Majadahonda, UAM, Spain 0
BC Cancer Agency (BCCA), PHSA, Canada 0
NIH NIEHS Epigenetics and Stem Cell Biology Laboratory (ESCBL), United States of America (USA) 0
Centre for Genetic Origins of Health and Disease (GOHaD), Australia 0
UNC Gillings School of Global Public Health (SPH), United States of America (USA) 0
University of Pittsburgh School of Medicine (UPSOM), United States of America (USA) 0
Genetic Epidemiology Research Institute (GERI), UCI, United States of America (USA) 0
Department of Epidemiology (EPI), UCI, United States of America (USA) 0
Queen's Cancer Research Institute (QCRI), Queen's University, Canada 0
Department of Public Health Sciences, Queen's University, Canada 0
Joseph J. Zilber School of Public Health, UWM, United States of America (USA) 0
UNC Lineberger Comprehensive Cancer Center, United States of America (USA) 0
ICR Division of Breast Cancer Research, United Kingdom (UK) 0
Institute of Human Genetics, Pontifical Xaverian University, Colombia 0
NIHR Oxford Biomedical Research Centre (OxBRC), United Kingdom (UK) 0
Institute of Cancer and Genomic Sciences, UB, United Kingdom (UK) 0
School of Dental Medicine, Pitt, United States of America (USA) 0
Örebro University Hospital, Sweden 0
Shaukat Khanum Memorial Cancer Hospital and Research Centre (SKMCH & RC), Pakistan 0
Westmead Institute for Medical Research, Australia 0
Department of Biology, UNIPI, Italy 0
The University of Sydney (USYD), Australia 0
School of Medicine (SOM), UC San Diego, United States of America (USA) 0
Department of Human Genetics, KU Leuven, Belgium 0
Department of Molecular Medicine and Surgery (MMK), KI, Sweden 0
Karolinska University Hospital, Sweden 0
VIB-KU Leuven Center for Cancer Biology (CCB), Belgium 0
University of Tübingen (Uni Tübingen), Germany 0
Department of Family Medicine and Public Health (FMPH), UC San Diego, United States of America (USA) 0
UiO Institute of Clinical Medicine (Klinmed), Norway 0
UiO Institute for Cancer Research, Norway 0
Medical Faculty Mannheim, Uni Heidelberg, Germany 0
State Research Institute Centre for Innovative Medicine (IMC), Lithuania 0
Vilnius University Hospital Santariskiu Klinikos (Santariškių Klinikos), VU, Lithuania 0
University Health Network (UHN), U of T, Canada 0
Wythenshawe Hospital, MFT, United Kingdom (UK) 0
Department of Laboratory Medicine and Pathobiology (LMP), U of T, Canada 0
Center for Clinical Cancer Genetics and Global Health, UChicago, United States of America (USA) 0
Department of Clinical Sciences - Lund, LU, Sweden 0
Sheffield Institute for Nucleic Acids (SInFoNiA), The University of Sheffield, United Kingdom (UK) 0
Department of Oncology and Metabolism, The University of Sheffield, United Kingdom (UK) 0
Cedars-Sinai Center for Bioinformatics and Functional Genomics, United States of America (USA) 0
Cedars-Sinai Genomics Core, United States of America (USA) 0
Department of Medicine, MSKCC, United States of America (USA) 0
UCLA David Geffen School of Medicine (DGSOM), United States of America (USA) 0
Johns Hopkins University School of Medicine (JHUSOM), JHU, United States of America (USA) 0
Department of Clinical Pathology, UniMelb, Australia 0
Galician Foundation of Genomic Medicine (FPGMX), Spain 0
Faculty of Medicine, UNSW Sydney, Australia 0
Lowy Cancer Research Centre, Australia 0
Royal Victoria Hospital (RVH), McGill University, Canada 0
Sir Peter MacCallum Department of Oncology, UniMelb, Australia 0
Peter MacCallum Cancer Centre (Peter Mac), Australia 0
Translational Cancer Research Area, UEF, Finland 0
Kuopio University Hospital (KUH), Finland 0
Department of Non-communicable Disease Epidemiology (NCDE), LSHTM, United Kingdom (UK) 0
Clinical Pathology and Forensic Medicine, UEF, Finland 0
Department of Medicine, McGill University, Canada 0
NIHR Cambridge Biomedical Research Centre (Cambridge BRC), United Kingdom (UK) 0
Gerald Bronfman Department of Oncology, McGill University, Canada 0
Department of Human Genetics, McGill University, Canada 0
University of Malaya Medical Centre (UMMC), Malaysia 0
N.N. Alexandrov National Cancer Centre of Belarus for Oncology and Medical Radiology, Belarus 0
Cluster of Excellence - Image-Guided and Functionally Instructed Tumor Therapies (iFIT), Uni Tübingen, Germany 0
The Kinghorn Cancer Centre (TKCC), Australia 0
Faculty of Health and Medical Sciences, UCPH, Denmark 0
Department of Medicine (DOM), BWH, United States of America (USA) 0
Biocenter Oulu, University of Oulu, Finland 0
Northern Finland Laboratory Centre (NordLab), Finland 0
Department of Molecular Genetics, U of T, Canada 0
Cyprus Institute of Neurology and Genetics (CING), Cyprus 0
Cyprus School of Molecular Medicine (CSMM), CING, Cyprus 0
Harvard Medical School (HMS), United States of America (USA) 0

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