Multi-ancestry genome-wide gene–smoking interaction study of 387,272 individuals identifies new loci associated with serum lipids

Journal: Nature Genetics

Published: 2019-03-29

DOI: 10.1038/s41588-019-0378-y

Affiliations: 235

Authors: 301

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Institutions FC
Los Angeles BioMedical Research Institute at Harbor-UCLA Medical Center (LA BioMed), United States of America (USA) 0.03
NIH NHGRI Center for Research on Genomics and Global Health, United States of America (USA) 0.02
Department of Genetics, WUSTL, United States of America (USA) 0.02
Division of Biostatistics, WUSTL, United States of America (USA) 0.02
MRC Epidemiology Unit, University of Cambridge, United Kingdom (UK) 0.02
UNC Department of Epidemiology, United States of America (USA) 0.02
Department of Biostatistics, BU, United States of America (USA) 0.01
Department of Epidemiology, U-M, United States of America (USA) 0.01
Singapore Eye Research Institute (SER), SNEC, Singapore 0.01
Department of Epidemiology, Erasmus MC, Netherlands 0.01
Department of Epidemiology, RUG, Netherlands 0.01
Department of Biostatistics and Data Science (BDS), WFU, United States of America (USA) 0.01
Department of Cardiology, RUG, Netherlands 0.01
Survey Research Center (SRC), U-M, United States of America (USA) 0.01
Institute of Clinical Medicine, UEF, Finland 0.01
Department of Biostatistics, UW, United States of America (USA) 0.01
MRC-PHE Centre for Environment and Health, United Kingdom (UK) 0.01
Oxford Wellcome Trust Centre for Human Genetics, United Kingdom (UK) 0.01
Department of Medical Epidemiology and Biostatistics (MEB), KI, Sweden 0.01
Laboratory of Genetics and Molecular Cardiology, HCFMUSP, Brazil 0.01
Division of Preventive Medicine, BWH, United States of America (USA) 0.01
MRC Institute of Genetics and Molecular Medicine (IGMM), United Kingdom (UK) 0.01
Jackson Heart Study (JHS), United States of America (USA) 0.01
NIH NIA Laboratory of Epidemiology and Population Science (LEPS), United States of America (USA) 0.01
Division of Epidemiology, VU, United States of America (USA) 0.01
Department of Population and Quantitative Health Sciences, CWRU, United States of America (USA) 0.01
Division of Sleep and Circadian Disorders, BWH, United States of America (USA) 0.01
National Heart and Lung Institute (NHLI), ICL, United Kingdom (UK) 0.01
Human Genetics Center (HGC), UTHealth, United States of America (USA) 0.01
Genome Institute of Singapore (GIS), A*STAR, Singapore 0.01
Department of Epidemiology, Human Genetics, and Environmental Sciences (EHGES), UTHealth, United States of America (USA) 0.01
Charles Bronfman Institute for Personalized Medicine (IPM), ISMMS, United States of America (USA) 0.01
IRCCS Materno Infantile Burlo Garofolo, Italy 0.01
European Genomic Institute for Diabetes (EGID), France 0.01
Estonian Genome Center, UT, Estonia 0.01
Foundation for Research in Health Exercise and Nutrition (KULTU), Finland 0.01
Institute of Genomics, UT, Estonia 0.01
National University Health System (NUHS), Singapore 0.01
NUS Saw Swee Hock School of Public Health (SSHPH), Singapore 0.01
Department of Gene Diagnostics and Therapeutics, NCGM, Japan 0.01
UNC Department of Genetics, United States of America (USA) 0.01
Amsterdam Neuroscience, Netherlands 0.01
Institute of Dentistry, QMUL, United Kingdom (UK) 0.01
Wake Forest School of Medicine (WFSM), WFU, United States of America (USA) 0.01
Institute of Epidemiology I (EPI I), HMGU, Germany 0.01
Department of Public Health, UoK, Sri Lanka 0.01
RIKEN Laboratory for Statistical Analysis, Japan 0.01
NIH National Institute on Aging (NIA), United States of America (USA) 0.01
Department of Public Health Sciences, LUC, United States of America (USA) 0.01
Division of General Internal Medicine, JHU, United States of America (USA) 0.01
Center for Public Health Genomics (CPHG), UVA, United States of America (USA) 0.01
Human Genomics Laboratory, PBRC LSU, United States of America (USA) 0.01
Department of Biochemistry, WFU, United States of America (USA) 0.01
Department of Epidemiology and Biostatistics (EBS), ICL, United Kingdom (UK) 0.01
Beijing Tongren Eye Center, Beijing Tongren Hospital, China 0.01
Department of Medicine, Surgery and Health Sciences, UNITS, Italy 0
Sanger Institute Human Genetics, United Kingdom (UK) 0
Institute of Environmental Medicine (IMM), KI, Sweden 0
Unit for Cardiovascular Medicine, KI, Sweden 0
MRC London Institute of Medical Sciences (LMS), United Kingdom (UK) 0
Center for Statistical Genetics (CSG), U-M, United States of America (USA) 0
Federal University of Pelotas (UFPel), Brazil 0
Department of Biostatistics, U-M, United States of America (USA) 0
Oxford Division of Cardiovascular Medicine (CVM), United Kingdom (UK) 0
State Key Laboratory of Environment and Health (Wuhan), HUST, China 0
Duke-NUS Ophthalmology and Visual Sciences Academic Clinical Program (EYE-ACP), Singapore 0
Department of Occupational and Environmental Health, HUST, China 0
Harvard Department of Medicine, United States of America (USA) 0
Department of Clinical Epidemiology, Leiden University, Netherlands 0
Centre for Cognitive Ageing and Cognitive Epidemiology (CCACE), The University of Edinburgh, United Kingdom (UK) 0
Brown Foundation Institute of Molecular Medicine for the Prevention of Human Diseases (IMM), UTHealth, United States of America (USA) 0
Department of Public Health, University of Split, Croatia 0
NUS Department of Medicine, Singapore 0
Cardiovascular Health Research Unit (CHRU), United States of America (USA) 0
Carver College of Medicine, UI, United States of America (USA) 0
School of Medicine (SOM), UMB, United States of America (USA) 0
Department of Human Genetics, Pitt, United States of America (USA) 0
Institute for Medical Informatics, Biometry and Epidemiology (IBE), LMU, Germany 0
Framingham Heart Study (FHS), United States of America (USA) 0
Laboratory of Genome Technology, UTokyo, Japan 0
Department of Psychiatry, RUG, Netherlands 0
Division of Public Health Sciences (PHS), WFU, United States of America (USA) 0
Clinic of Psychiatry and Psychotherapy, University of Greifswald, Germany 0
Collaborative Health Studies Coordinating Center (CHSCC), United States of America (USA) 0
University of Washington School of Medicine (UWSOM), United States of America (USA) 0
Department of Epidemiology, Tulane University, United States of America (USA) 0
University of the West Indies (UWI Jamaica), Jamaica 0
School of Medicine, Ole Miss, United States of America (USA) 0
Faculty of Medicine, UoK, Sri Lanka 0
Department of Psychiatry, WUSTL, United States of America (USA) 0
Section on Nephrology, WFU, United States of America (USA) 0
Mayo Clinic Division of Nephrology and Hypertension, United States of America (USA) 0
Caribbean Institute for Health Research (CAIHR), UWI Jamaica, Jamaica 0
Institute for Community Medicine (ICM), University of Greifswald, Germany 0
RIKEN Laboratory for Genotyping Development, Japan 0
Centre for Global Health Research, The University of Edinburgh, United Kingdom (UK) 0
Department of Preventive Medicine, NU, United States of America (USA) 0
School of Public Health (SPH), ICL, United Kingdom (UK) 0
UAB Department of Medicine (DOM), United States of America (USA) 0
Aberdeen Biomedical Imaging Centre (ABIC), University of Aberdeen, United Kingdom (UK) 0
Division of Epidemiology and Community Health, UMN, United States of America (USA) 0
NIHR Barts Biomedical Research Centre (BRC), United Kingdom (UK) 0
Kaiser Permanente Division of Research, United States of America (USA) 0
NIH NHLBI Division of Cardiovascular Sciences (DCVS), United States of America (USA) 0
Stanford Department of Genetics, United States of America (USA) 0
RIKEN Center for Integrative Medical Sciences (IMS), Japan 0
School of Public Health, UW, United States of America (USA) 0
Fred Hutchinson Cancer Research Center (FHCRC), United States of America (USA) 0
Danish Aging Research Center (DARC), Denmark 0
Ninewells Hospital and Medical School, United Kingdom (UK) 0
USC Division of Biostatistics, United States of America (USA) 0
Department of Epidemiology and Biostatistics, UGA, United States of America (USA) 0
Department of Gerontology and Geriatrics, Leiden University, Netherlands 0
Taub Institute for Research on Alzheimer's Disease and the Aging Brain, CU, United States of America (USA) 0
Glenfield Hospital, United Kingdom (UK) 0
Department of Internal Medicine, Leiden University, Netherlands 0
NIHR Leicester Respiratory Biomedical Research Unit (BRU), United Kingdom (UK) 0
McKusick-Nathans Institute of Genetic Medicine, JHU, United States of America (USA) 0
Department of Cardiovascular Sciences, University of Leicester, United Kingdom (UK) 0
Icelandic Heart Association (IHA), Iceland 0
Faculty of Medicine, University of Iceland, Iceland 0
NUS Department of Ophthalmology, Singapore 0
Institute of Clinical Chemistry and Laboratory Medicine, University of Greifswald, Germany 0
DZHK Partner Site Greifswald, Germany 0
Finnish Cardiovascular Research Center-Tampere, UTA, Finland 0
Women's Health Initiative Clinical Coordinating Center, FHCRC, United States of America (USA) 0
Harvard Medical School (HMS), United States of America (USA) 0
Fimlab Laboratories Ltd., Finland 0
Department of Ophthalmology, Taichung Veterans General Hospital, Taiwan 0
Lehrstuhl für Genetische Epidemiologie, UR, Germany 0
Research Unit of Molecular Epidemiology (AME), HMGU, Germany 0
Department of Cardiology, LNWH, United Kingdom (UK) 0
Department of Internal Medicine, NTUH, Taiwan 0
College of Medicine (CM), NTU, Taiwan 0
Institute of Biomedicine, UEF, Finland 0
Department of Internal Medicine, Taichung Veterans General Hospital, Taiwan 0
School of Medicine, NYMU, Taiwan 0
Department of Medicine, UW, United States of America (USA) 0
Lund University Diabetes Centre (LUDC), LU, Sweden 0
Genetic and Molecular Epidemiology (GAME) Unit, LU, Sweden 0
Skåne University Hospital (SUS), Sweden 0
TUM-HMGU Institute of Human Genetics (IHG), Germany 0
Duke-NUS Graduate Medical School Singapore, Singapore 0
Beijing Key Laboratory of Ophthalmology and Visual Science, Beijing Tongren Hospital, China 0
Beijing Institute of Ophthalmology, Beijing Tongren Hospital, China 0
Department of Epidemiology, UW, United States of America (USA) 0
Department of Hygiene and Epidemiology, UOI, Greece 0
Department of Public Health and Primary Care (PHEG), Leiden University, Netherlands 0
Oxford Nuffield Department of Population Health (NDPH), United Kingdom (UK) 0
Centre for Genomic and Experimental Medicine (CGEM), United Kingdom (UK) 0
The Mindich Child Health and Development Institute (MCHDI), ISMMS, United States of America (USA) 0
Institute of Translational Genomics (ITG), HMGU, Germany 0
Department of Genetics, RUG, Netherlands 0
MRC Integrative Epidemiology Unit (IEU), UoB, United Kingdom (UK) 0
Department of Epidemiology, Pitt, United States of America (USA) 0
Department of Gerontology and Geriatrics, WFU, United States of America (USA) 0
Clinical and Translational Epidemiology Unit (CTEU), MGH, United States of America (USA) 0
German Center for Diabetes Research (DZD), Germany 0
Department of Genomics of Common Disease, ICL, United Kingdom (UK) 0
UPMC Hillman Cancer Center (UPCI), United States of America (USA) 0
Center on Diabetes, Obesity and Metabolism (CDOM), WFU, United States of America (USA) 0
Alzheimer Scotland Dementia Research Centre (ASDRC), The University of Edinburgh, United Kingdom (UK) 0
Institute of Genetic Epidemiology (IGE), HMGU, Germany 0
Harvard Department of Epidemiology, United States of America (USA) 0
Harvard Department of Social and Behavioral Sciences, United States of America (USA) 0
Center of Bioinformatics, Biostatistics and Integrative Biology (C3BI), France 0
Department of Psychology, The University of Edinburgh, United Kingdom (UK) 0
Department of Internal Medicine, Erasmus MC, Netherlands 0
Tri-Service General Hospital, Taiwan 0
Data Tecnica International, United States of America (USA) 0
School of Medicine, NDMC, Taiwan 0
Faculty of Medicine, MUMS, Iran 0
State Key Laboratory of Oncogenes and Related Genes (SKLORG) at Renji Hospital, SJTU, China 0
NIH NIA Laboratory of Neurogenetics, United States of America (USA) 0
Department of Epidemiology at Renji Hospital, SJTU, China 0
Khoo Teck Puat - National University Children’s Medical Institute (KTP-NUCMI), NUH, Singapore 0
NUS Department of Paediatrics, Singapore 0
Cardiovascular Research Institute (CVRI), BCM, United States of America (USA) 0
Houston Methodist DeBakey Heart and Vascular Center, United States of America (USA) 0
Faculty / Graduate School of Medicine, Osaka University, Japan 0
Hadassah Medical Center, HUJI, Israel 0
Braun School of Public Health and Community Medicine, HUJI, Israel 0
Department of Medicine, CU, United States of America (USA) 0
Department of Epidemiology, Brown University, United States of America (USA) 0
Department of Family Medicine, Brown University, United States of America (USA) 0
Department of Epidemiology, CU, United States of America (USA) 0
Cardiovascular Division, WUSTL, United States of America (USA) 0
Department of Clinical Gene Therapy (CGT), Osaka University, Japan 0
Beth Israel Deaconess Medical Center (BIDMC), United States of America (USA) 0
Novo Nordisk Foundation Center for Basic Metabolic Research (CBMR), UCPH, Denmark 0
Sticht Center for Healthy Aging and Alzheimer’s Prevention, WFU, United States of America (USA) 0
Department of Biostatistics, University of Liverpool, United Kingdom (UK) 0
Department of Internal Medicine, WFU, United States of America (USA) 0
Department of Environmental Medicine and Public Health, ISMMS, United States of America (USA) 0
Lee Kong Chian School of Medicine, Singapore 0
Imperial College Healthcare NHS Trust, United Kingdom (UK) 0
Human Genome Sequencing Center (HGSC), BCM, United States of America (USA) 0
Psychiatric Hospital "Sveti Ivan", Croatia 0
Department of Medicine, MCW, United States of America (USA) 0
Gen-Info Ltd., Croatia 0
Department of Pediatrics, MCW, United States of America (USA) 0
Department of Clinical Physiology and Nuclear Medicine, UTU, Finland 0
Turku University Hospital (TYKS), UTU, Finland 0
Research Centre of Applied and Preventive Cardiovascular Medicine (CAPC), UTU, Finland 0
Technical University of Munich (TUM), Germany 0
College of Medicine, CSMU, Taiwan 0
Department of Physiology, MCW, United States of America (USA) 0
Broad Institute of MIT and Harvard, United States of America (USA) 0
Department of Clinical Physiology and Nuclear Medicine, UEF, Finland 0
Department of Radiology and Nuclear Medicine, Erasmus MC, Netherlands 0
National Taiwan University Hospital (NTUH), Taiwan 0
Department of Neurology, Erasmus MC, Netherlands 0
NUS Department of Biochemistry (BCH), Singapore 0
Medical Faculty Mannheim, Uni Heidelberg, Germany 0
Translational Laboratory in Genetic Medicine (TLGM), Singapore 0
Department of Biobank Research, UMU, Sweden 0
Kaiser Permanente Washington Health Research Institute (KPWHRI), United States of America (USA) 0
Department of Health Services, UW, United States of America (USA) 0
NUS Department of Statistics and Applied Probability, Singapore 0
Harvard Department of Nutrition, United States of America (USA) 0
Department of Public Health and Clinical Medicine, UMU, Sweden 0
Oxford Centre for Diabetes, Endocrinology and Metabolism (OCDEM), United Kingdom (UK) 0
NUS Graduate School for Integrative Sciences and Engineering (NGS), Singapore 0
NUS Life Sciences Institute (LSI), Singapore 0

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