The mutational constraint spectrum quantified from variation in 141,456 humans

Journal: Nature

Published: 2020-05-27

DOI: 10.1038/s41586-020-2308-7

Affiliations: 170

Authors: 177

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Institutions Share
Broad Institute of MIT and Harvard, United States of America (USA) 0.29
Massachusetts General Hospital (MGH), United States of America (USA) 0.10
Harvard University, United States of America (USA) 0.03
Icahn School of Medicine at Mount Sinai (ISMMS), MSHS, United States of America (USA) 0.02
Cardiff University, United Kingdom (UK) 0.02
National Institute for Health and Welfare (THL), Finland 0.02
Institute for Molecular Medicine Finland (FIMM), Finland 0.02
University of Helsinki, Finland 0.02
Lund University (LU), Sweden 0.01
Helsinki University Central Hospital (HUCH), Finland 0.01
Lerner Research Institute, Cleveland Clinic, United States of America (USA) 0.01
Center for Genome Science (CGS), KNIH, South Korea 0.01
University of Mississippi Medical Center (UMMC), Ole Miss, United States of America (USA) 0.01
The Chinese University of Hong Kong (CUHK), China 0.01
NIHR Leicester Cardiovascular Biomedical Research Unit (LCBRU), United Kingdom (UK) 0.01
Saint Antoine Hospital, France 0.01
Columbia University Irving Medical Center (CUIMC), CU, United States of America (USA) 0.01
Yale University, United States of America (USA) 0.01
Imperial College London (ICL), United Kingdom (UK) 0.01
University of Tartu (UT), Estonia 0.01
Kuopio University Hospital (KUH), Finland 0.01
Vanderbilt University Medical Center (VUMC), United States of America (USA) 0.01
University of Eastern Finland (UEF), Finland 0.01
Seoul National University Hospital (SNUH), South Korea 0.01
National Institute of Medical Science and Nutrition Salvador Zubiran (INCMNSZ), Mexico 0.01
Boston University (BU), United States of America (USA) 0.01
Brigham and Women's Hospital (BWH), United States of America (USA) 0.01
Samfundet Folkhälsan, Finland 0.01
National Institute of Public Health of Mexico (INSP), Mexico 0.01
Woodruff Health Sciences Center (WHSC), Emory University, United States of America (USA) 0.01
University of Oxford, United Kingdom (UK) 0.01
Shaare Zedek Medical Center (SZMC), Israel 0.01
University Medical Center Groningen (UMCG), RUG, Netherlands 0.01
UC San Diego Health Sciences, United States of America (USA) 0.01
The University of Texas Health Science Center at Houston (UTHealth), United States of America (USA) 0.01
Johns Hopkins University (JHU), United States of America (USA) 0.01
National University of Singapore (NUS), Singapore 0.01
King's College London (KCL), United Kingdom (UK) 0.01
Tampere University, Finland 0.01
Fimlab Laboratories Ltd., Finland 0.01
Cedars-Sinai Medical Center (Cedars-Sinai), United States of America (USA) 0.01
University of Ottawa (uOttawa), Canada 0.01
Medical Research Center Oulu (MRC Oulu), Finland 0.01
The Institute of Cancer Research (ICR), United Kingdom (UK) 0.01
National Institute of Genomic Medicine (INMEGEN), Mexico 0.01
Ninewells Hospital and Medical School, United Kingdom (UK) 0.01
University of Southern California (USC), United States of America (USA) 0.01
Skåne University Hospital (SUS), Sweden 0.01
Upstate University Hospital, SUNY Upstate Medical University, United States of America (USA) 0.01
Hadassah Medical Center, HUJI, Israel 0.01
McLean Hospital, United States of America (USA) 0.01
UW Medicine, United States of America (USA) 0.01
Wellcome Trust Genome Campus, United Kingdom (UK) 0.01
University Medical Center Schleswig-Holstein - Campus Kiel (UKSH Kiel), Germany 0.01
University Hospitals Parma Medical Center, Italy 0.01
University of Michigan (U-M), United States of America (USA) 0.01
NIH National Human Genome Research Institute (NHGRI), United States of America (USA) 0.01
Wake Forest Baptist Health, WFU, United States of America (USA) 0.01
Peninsula College of Medicine and Dentistry (PCMD), United Kingdom (UK) 0.01
Colorado School of Public Health, United States of America (USA) 0.01
Texas Biomedical Research Institute (Texas Biomed), United States of America (USA) 0.01
University of Illinois at Chicago (UIC), United States of America (USA) 0.01
University of California, Irvine (UCI), United States of America (USA) 0.01
MRC London Institute of Medical Sciences (LMS), United Kingdom (UK) 0
Biomedical Research Networking Centers (CIBER), Spain 0
Hospital del Mar Medical Research Institute (IMIM), Spain 0
Karolinska Institute (KI), Sweden 0
Framingham Heart Study (FHS), United States of America (USA) 0
Royal Brompton and Harefield NHS Foundation Trust, United Kingdom (UK) 0
University of Lübeck, Germany 0
The University of North Carolina at Chapel Hill (UNC), United States of America (USA) 0
National University Health System (NUHS), Singapore 0
Albert Einstein College of Medicine (Einstein), United States of America (USA) 0
Seoul National University (SNU), South Korea 0
National Autonomous University of Mexico (UNAM), Mexico 0
Barts Health NHS Trust, United Kingdom (UK) 0
Montreal Heart Institute, UdeM, Canada 0
University of Montreal (UdeM), Canada 0
William Harvey Research Institute (WHRI), QMUL, United Kingdom (UK) 0
TUM German Heart Centre Munich (DHM), Germany 0
Technical University of Munich (TUM), Germany 0
VA Tennessee Valley Healthcare System, United States of America (USA) 0
Imperial College Healthcare NHS Trust, United Kingdom (UK) 0
Ealing Hospital, LNWH, United Kingdom (UK) 0
Australian Centre for Population Genomics, Australia 0
DZHK Partner Site Hamburg/Kiel/Lübeck, Germany 0
Duke-NUS Medical School, Singapore 0
University of Pennsylvania Health System (UPHS), United States of America (USA) 0
Vertex Pharmaceuticals Incorporated, United States of America (USA) 0
Center for Non-Communicable Diseases (CNCD), Pakistan 0
Oxford Centre for Diabetes, Endocrinology and Metabolism (OCDEM), United Kingdom (UK) 0
University of Pennsylvania (Penn), United States of America (USA) 0
University of Vic - Central University of Catalonia (UVic-UCC), Spain 0
University of Haifa (HU), Israel 0
NIHR Oxford Biomedical Research Centre (OxBRC), United Kingdom (UK) 0
Oxford Wellcome Trust Centre for Human Genetics, United Kingdom (UK) 0
Department of Genetics and Genomic Sciences, ISMMS, United States of America (USA) 0
Boston Children's Hospital (BCH), United States of America (USA) 0
University of New South Wales (UNSW Sydney), Australia 0

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