Complement genes contribute sex-biased vulnerability in diverse disorders

Journal: Nature

Published: 2020-05-11

DOI: 10.1038/s41586-020-2277-x

Affiliations: 282

Authors: 415

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Institutions Share
Wellcome Trust Genome Campus, United Kingdom (UK) 0.06
Lieber Institute for Brain Development (LIBD), United States of America (USA) 0.04
Stanley Center for Psychiatric Research, Broad Institute, United States of America (USA) 0.04
Institute of Psychological Medicine and Clinical Neurosciences, Cardiff University, United Kingdom (UK) 0.02
MRC Centre for Neuropsychiatric Genetics and Genomics (CNGG), Cardiff University, United Kingdom (UK) 0.02
VCU Virginia Institute for Psychiatric and Behavioral Genetics (VIPBG), United States of America (USA) 0.02
Institute of Psychiatry, Psychology and Neuroscience (IOPPN), KCL, United Kingdom (UK) 0.02
Department of Psychiatry, TCD, Ireland 0.02
Department of Psychiatry, ISMMS, United States of America (USA) 0.02
UNC Department of Genetics, United States of America (USA) 0.02
Queensland Brain Institute (QBI), UQ, Australia 0.01
Harvard Department of Genetics, United States of America (USA) 0.01
Schizophrenia Research Institute, Australia 0.01
Department of Medical and Molecular Genetics, KCL, United Kingdom (UK) 0.01
Department of Psychiatry, Psychotherapy and Psychosomatics, MLU, Germany 0.01
Division of Psychiatry, The University of Edinburgh, United Kingdom (UK) 0.01
National Institute for Health and Welfare (THL), Finland 0.01
Analytic and Translational Genetics Unit (ATGU), MGH, United States of America (USA) 0.01
Department of Psychiatry, HKU, China 0.01
Clinical Neuroscience, MPI-EM, Germany 0.01
Department of Medical Epidemiology and Biostatistics (MEB), KI, Sweden 0.01
The Lundbeck Foundation Initiative for Integrative Psychiatric Research (iPSYCH), Denmark 0.01
UCL Division of Psychiatry, United Kingdom (UK) 0.01
Institute of Mental Health (IMH), Singapore 0.01
Program in Medical and Population Genetics, Broad Institute, United States of America (USA) 0.01
UCLA Center for Neurobehavioral Genetics (CNG), United States of America (USA) 0.01
Estonian Genome Center, UT, Estonia 0.01
USC Zilkha Neurogenetic Institute (ZNI), United States of America (USA) 0.01
Janssen Research & Development (J&J PRD), Raritan, United States of America (USA) 0.01
deCODE Genetics, Inc., Iceland 0.01
King's College London (KCL), United Kingdom (UK) 0.01
Department of Psychiatry, UvA, Netherlands 0.01
Institute of Molecular Genetics (IMG), RAS, Russia 0.01
Pfizer Worldwide Research & Development (WRD), United States of America (USA) 0.01
Pamela Sklar Division of Psychiatric Genomics, ISMMS, United States of America (USA) 0.01
Norwegian Centre for Mental Disorders Research (NORMENT), Norway 0.01
Medical Faculty Mannheim, Uni Heidelberg, Germany 0.01
Department for Genetic Epidemiology in Psychiatry, CIMH, Germany 0.01
Priority Research Centre for Brain and Mental Health Research (CBMHR), UON, Australia 0.01
UMC Department of Psychiatry, Netherlands 0.01
UMC Utrecht Brain Center Rudolf Magnus, Netherlands 0.01
Stanford Department of Psychiatry and Behavioral Sciences, United States of America (USA) 0.01
Harvard Department of Psychiatry, United States of America (USA) 0.01
UCLA Department of Human Genetics, United States of America (USA) 0.01
Department of Psychiatry and Behavioral Sciences, JHU, United States of America (USA) 0.01
Department of Psychiatry, CU Anschutz, United States of America (USA) 0
Department of Genetics, RUG, Netherlands 0
Department of Psychiatry, WUSTL, United States of America (USA) 0
Roche Pharma Research and Early Development (Roche pRED), Switzerland 0
Instituto de Formación e Investigación Marqués de Valdecilla (IFIMAV), HUMV, Spain 0
Chaim Sheba Medical Center at Tel HaShomer, Israel 0
Latvian Biomedical Research and Study Centre (BMC), Latvia 0
Faculty of Medicine, UOA, Greece 0
EURON, Netherlands 0
UCSF The Rosalind Russell/Ephraim P. Engleman Rheumatology Research Center, United States of America (USA) 0
Institute of Neurology (CIN), MUW, Austria 0
SUNY Downstate Health Sciences University (SUNY Downstate), United States of America (USA) 0
Department of Clinical Biochemistry, Immunology and Genetics, SSI, Denmark 0
MRC Centre for Social, Genetic and Developmental Psychiatry (SGDP), KCL, United Kingdom (UK) 0
Division of Psychiatry, UMU, Sweden 0
Eli Lilly and Company Ltd., United Kingdom (UK) 0
Vall d'Hebron Research Institute (VHIR), HUVH ICS, Spain 0
Faculty of Medicine, VU, Lithuania 0
Department of Medical Genetics, Medical University of Sofia, Bulgaria 0
Department of Psychiatry, Fujita Health University, Japan 0
Department of Psychiatry, CU, United States of America (USA) 0
Department of Psychiatry, RUG, Netherlands 0
Centre for Psychiatry Research, KI, Sweden 0
Research Institute for Biological Psychiatry (IBP), Region Hovedstadens Psykiatriske Hospital, Denmark 0
Department of Genomics, Uni Bonn, Germany 0
Life and Brain Center, Uni Bonn, Germany 0
Institute of Human Genetics, Uni Bonn, Germany 0
Psychiatric and Neurodevelopmental Genetics Unit (PNGU), MGH, United States of America (USA) 0
NorthShore Department of Psychiatry and Behavioral Sciences, United States of America (USA) 0
Department of General Psychiatry at Medical Faculty Heidelberg, Uni Heidelberg, Germany 0
Department of Psychiatry and Behavioral Neuroscience, UChicago, United States of America (USA) 0
Guy's Hospital, Guy's and St Thomas' NHS Foundation Trust, United Kingdom (UK) 0
Department of Psychiatry and Psychotherapy, LMU, Germany 0
Department of Human Genetics, A*STAR, Singapore 0
Centre for Medical Research (CMR), UWA, Australia 0
School of Biomedical Sciences and Pharmacy, UON, Australia 0
School of Psychiatry and Clinical Neurosciences, UWA, Australia 0
UNC Department of Psychiatry, United States of America (USA) 0
National Centre for Mental Health (NCMH), United Kingdom (UK) 0
Section Structural and functional Organisation of the Brain (INM-1), FZJ, Germany 0
Department of Psychiatry, U of T, Canada 0
State Key Laboratory for Brain and Cognitive Sciences, HKU, China 0
Campbell Family Mental Health Research Institute, U of T, Canada 0
Centre for Integrative Sequencing (iSEQ), AU, Denmark 0
Department of Psychiatry, MGH, United States of America (USA) 0
School of Medicine and Surgery, UNIVR, Italy 0
Psychiatric Laboratory, WCSM/WCH SCU, China 0
Discipline of Psychiatry, NUI Galway, Ireland 0
Department of Psychiatry and Psychotherapy, Uni Bonn, Germany 0
Department of Mental Health, JHU, United States of America (USA) 0
Department of Genetics and Pathology, PMU, Poland 0
State Mental Hospital Haar, Germany 0
Department of Biostatistics, JHU, United States of America (USA) 0
Hadassah Medical Center, HUJI, Israel 0
Mental Health Center, WCSM/WCH SCU, China 0
Beth Israel Deaconess Medical Center (BIDMC), United States of America (USA) 0
Institute of Medical Sciences (IMS), University of Aberdeen, United Kingdom (UK) 0
UC Department of Pediatrics, United States of America (USA) 0
Department of Biology and Medical Genetics, CU, Czech Republic 0
UAB Division of Clinical Immunology and Rheumatology, United States of America (USA) 0
Biomedical Research Networking Center for Mental Health Network (CIBERSAM), Spain 0
Medical School, PTE, Hungary 0
Szentágothai Research Centre, PTE, Hungary 0
UiO Division of Mental Health and Addiction, Norway 0
Faculty of Medicine, Medical University of Sofia, Bulgaria 0
Department of Psychiatry and Psychotherapy, FAU, Germany 0
UC Center for Autoimmune Genomics and Etiology (CAGE), United States of America (USA) 0
Genentech, Inc., United States of America (USA) 0
Oxford Department of Psychiatry, United Kingdom (UK) 0
NIH NCI Division of Cancer Epidemiology and Genetics (DCEG), United States of America (USA) 0
Faculty of Medical Sciences, University of Belgrade, Serbia 0
Department of Molecular and Cellular Therapeutics (MCT), RCSI, Ireland 0
Health Research Board, Ireland 0
Landspitali - The National University Hospital of Iceland, Iceland 0
Faculty of Physical Medicine and Rehabilitation (PMR), TSMU, Georgia 0
Faculty of Medicine, Health and Life Sciences, QUB, United Kingdom (UK) 0
Department of Psychiatry, RCSI, Ireland 0
DETECT Early Intervention Service for Psychosis, Ireland 0
University College London (UCL), United Kingdom (UK) 0
Eli Lilly and Company, United States of America (USA) 0
Queensland Centre for Mental Health Research (QCMHR), UQ, Australia 0
Department of Psychiatry and Psychotherapy, FSU, Germany 0
Oxford Wellcome Trust Centre for Human Genetics, United Kingdom (UK) 0
Royal Berkshire NHS Foundation Trust, United Kingdom (UK) 0
VA Boston Healthcare System, United States of America (USA) 0
Department of Genetics, HUJI, Israel 0
Wake Forest School of Medicine (WFSM), WFU, United States of America (USA) 0
University Hospital in Motol, Czech Republic 0
Department of Psychology and Neuroscience, CU-Boulder, United States of America (USA) 0
UCSF Department of Psychiatry, United States of America (USA) 0
Institute of Myology, France 0
University Clinic of Psychiatry, Macedonia 0
Princess Alexandra Hospital, Australia 0
Mental Health Research Center, RAMS, Russia 0
Department of Non-communicable Disease Epidemiology (NCDE), LSHTM, United Kingdom (UK) 0
Blue Note Biosciences, United States of America (USA) 0
Institute of Psychology (IP), CAS, China 0
Génétique du Cancer et des Maladies Neuropsychiatriques (GCMN), France 0
The University of Queensland Diamantina Institute (UQDI), UQ, Australia 0
Illumina, Inc., United States of America (USA) 0
Department of Psychiatry and Psychotherapy, UR, Germany 0
Ninewells Hospital and Medical School, United Kingdom (UK) 0
Neurosciences Clinical Academic Group (NCAG), SGUL, United Kingdom (UK) 0
UNC Department of Computer Science, United States of America (USA) 0
UCL Department of Molecular Neuroscience, United Kingdom (UK) 0
Oxford Department of Statistics, United Kingdom (UK) 0
Castle Peak Hospital, China 0
Department of Psychiatry, UCC, Ireland 0
Peninsula Dental School, University of Plymouth, United Kingdom (UK) 0
Helse Stavanger University Hospital, Norway 0
Wellcome Trust, United Kingdom (UK) 0
LSUHSC School of Nursing, LSU, United States of America (USA) 0
Department of Psychiatry, UI, United States of America (USA) 0
VCU Department of Psychiatry, United States of America (USA) 0
Friedman Brain Institute, ISMMS, United States of America (USA) 0
Icahn Institute for Genomics and Multiscale Biology, ISMMS, United States of America (USA) 0
Institute for Molecular Medicine Finland (FIMM), Finland 0
James J. Peters VA Medical Center, United States of America (USA) 0
Department of Biomedicine, AU, Denmark 0
MGH/HST Athinoula A. Martinos Center for Biomedical Imaging, United States of America (USA) 0
Icahn School of Medicine at Mount Sinai (ISMMS), MSHS, United States of America (USA) 0
Harry Perkins Institute of Medical Research (HPIMR), Australia 0
Center for Basic and Translational Obesity Research, BCH, United States of America (USA) 0
Centre for Clinical Research in Neuropsychiatry (CCRN), Australia 0
Department of Biomedicine Basel, Switzerland 0
Division of Endocrinology, BCH, United States of America (USA) 0
Discipline of Biochemistry, NUI Galway, Ireland 0
School of Psychology, NUI Galway, Ireland 0
Institute of Medical Science (IMS), U of T, Canada 0
Feinstein Institute for Medical Research, Northwell Health, United States of America (USA) 0
Centre for Child Health Research, UWA, Australia 0
Telethon Kids Institute, Australia 0
Centre for Integrated Register-Based Research at Aarhus University (CIRRAU), AU, Denmark 0
Cambridge Institute for Medical Research (CIMR), University of Cambridge, United Kingdom (UK) 0
The National Centre for Register-based Research, AU, Denmark 0
VCU Department of Human and Molecular Genetics, United States of America (USA) 0
Centre for Genomic Sciences, HKU, China 0
Donald and Barbara Zucker School of Medicine at Hofstra/Northwell, United States of America (USA) 0
Zucker Hillside Hospital, Northwell Health, United States of America (USA) 0
Aarhus University Hospital, Denmark 0
NUS Saw Swee Hock School of Public Health (SSHPH), Singapore 0
The University of Western Australia (UWA), Australia 0
Oxford Centre for Diabetes, Endocrinology and Metabolism (OCDEM), United Kingdom (UK) 0
Faculty of Medicine "Carl Gustav Carus", TU Dresden, Germany 0
Center for Statistical Genetics (CSG), U-M, United States of America (USA) 0
Faculty of Epidemiology and Population Health (EPH), LSHTM, United Kingdom (UK) 0
Addenbrooke's Hospital, United Kingdom (UK) 0
Faculty of Medicine (FMed), University of Oulu, Finland 0
UCL Research Department of Epidemiology and Public Health (EPH), United Kingdom (UK) 0
Oulu University Hospital (OUH), Finland 0
Department of Clinical Neurosciences, University of Cambridge, United Kingdom (UK) 0
Department of Biostatistics, U-M, United States of America (USA) 0
VIB-UAntwerp Center for Molecular Neurology (CMN), Belgium 0
Churchill Hospital, United Kingdom (UK) 0
Atlanta VA Medical Center, United States of America (USA) 0
School of Psychology, UON, Australia 0
Faculty of Medicine, Sorbonne University, France 0
Division of Cardiovascular Medicine, BWH, United States of America (USA) 0
School of Psychiatry, UNSW Sydney, Australia 0
Duke-NUS Graduate Medical School Singapore, Singapore 0
Department of Human Genetics, UChicago, United States of America (USA) 0
Department of Pediatrics, UChicago, United States of America (USA) 0
Laboratoire de Génétique Moléculaire de la Neurotransmission et des Processus Neurodégénératifs (LGN), France 0
AP-HP Pitié-Salpêtrière Hospital - Charles-Foix, France 0
Assistance Publique-Hôpitaux de Paris (AP-HP), France 0
Department of Psychiatry and Behavioral Sciences, Emory University, United States of America (USA) 0
Centre for Cognitive Ageing and Cognitive Epidemiology (CCACE), The University of Edinburgh, United Kingdom (UK) 0
Sørlandet Hospital HF, Norway 0
Institute for Intelligent Systems and Robotics (ISIR), France 0
University of California, Berkeley (UC Berkeley), United States of America (USA) 0
University of Antwerp (UA), Belgium 0
UiO Department of Medical Genetics (DMG), Norway 0
Harvard Department of Epidemiology, United States of America (USA) 0
Department of Psychiatry, University of Helsinki, Finland 0
Wolfson Institute of Preventive Medicine, QMUL, United Kingdom (UK) 0
Melbourne Neuropsychiatry Centre (MNC), Australia 0
Lawrence Berkeley National Laboratory (LBNL), United States of America (USA) 0
Royal Brisbane and Women's Hospital (RBWH), Australia 0
The University of Queensland (UQ), Australia 0
Moorfields Eye Hospital, Moorfields Eye Hospital NHS Foundation Trust, United Kingdom (UK) 0
Priority Research Centre for Health Behaviour (CHB), UON, Australia 0
School of Electrical Engineering and Computer Science, UON, Australia 0
Harvard Center for Brain Science (CBS), United States of America (USA) 0
NIHR Moorfields Biomedical Research Centre (BRC), United Kingdom (UK) 0
UCL Institute of Ophthalmology (IoO), United Kingdom (UK) 0
UMC Department of Medical Genetics, Netherlands 0
University of Barcelona (UB), Spain 0
UCL School of Life and Medical Sciences (SLMS), United Kingdom (UK) 0
UCL Institute of Cognitive Neuroscience (ICN), United Kingdom (UK) 0
Hunter New England Local Health District, Australia 0
Department of Psychiatry and Psychotherapy, University of Göttingen, Germany 0
Cluster of Excellence - Munich Cluster for Systems Neurology (SyNergy), LMU, Germany 0
Institute of Translational Medicine (ITM), University of Liverpool, United Kingdom (UK) 0
Diakonhjemmet Hospital, Diakonhjemmet Foundation, Norway 0
Max Planck Institute of Psychiatry, Germany 0
Department of Child and Adolescent Psychiatry/Psychology, Erasmus MC, Netherlands 0
Fundació per la Docència i Recerca, MútuaTerrassa, Spain 0
Department of Clinical Medicine, UCPH, Denmark 0
Department of Complex Trait Genetics (CTG), VUmc, Netherlands 0
Department of Functional Genomics (FGA), VUmc, Netherlands 0
McKusick-Nathans Institute of Genetic Medicine, JHU, United States of America (USA) 0
DTU Center for Biological Sequence Analysis (CBS), Denmark 0
Nash Family Department of Neuroscience, ISMMS, United States of America (USA) 0
Department of Neurology and Neurosurgery, JHU, United States of America (USA) 0
Folkhälsan Research Center, Finland 0
HUCH Unit of General Practice, Finland 0
Center for Human Genetic Research (CHGR), MGH, United States of America (USA) 0
Biomedicum Helsinki, Finland 0
Faculty of Mathematics and Natural Sciences, Uni Bonn, Germany 0
USC Department of Psychiatry and Behavioral Sciences, United States of America (USA) 0
Washington DC VA Medical Center, United States of America (USA) 0
Department of Psychiatry, Georgetown University, United States of America (USA) 0

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