Exceptionally low likelihood of Alzheimer’s dementia in APOE2 homozygotes from a 5,000-person neuropathological study

Journal: Nature Communications

Published: 2020-02-03

DOI: 10.1038/s41467-019-14279-8

Affiliations: 159

Authors: 192

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Institutions Share
Department of Pathology and Laboratory Medicine, Penn, United States of America (USA) 0.06
Arizona Alzheimer's Consortium (AAC), United States of America (USA) 0.03
UCSF Department of Neurology, United States of America (USA) 0.03
Department of Medicine, UW, United States of America (USA) 0.02
Mayo Clinic Department of Neuroscience, Florida Campus, United States of America (USA) 0.02
Mayo Clinic Department of Neurology, United States of America (USA) 0.02
UAB Department of Neurology, United States of America (USA) 0.02
Department of Neurology, Emory University, United States of America (USA) 0.02
Department of Psychiatry and Behavioral Sciences, UM, United States of America (USA) 0.02
Department of Psychiatry and Behavioral Sciences, UW, United States of America (USA) 0.02
Dr. John T. Macdonald Foundation Department of Human Genetics, UM, United States of America (USA) 0.02
John P. Hussman Institute for Human Genomics (HIHG), UM, United States of America (USA) 0.02
Department of Medical and Molecular Genetics, IUPUI, United States of America (USA) 0.01
Department of Neurology, CU, United States of America (USA) 0.01
Taub Institute for Research on Alzheimer's Disease and the Aging Brain, CU, United States of America (USA) 0.01
USC Department of Neurology, United States of America (USA) 0.01
Harvard Medical School (HMS), United States of America (USA) 0.01
Department of Pathology, Pitt, United States of America (USA) 0.01
Department of Neurology, BU, United States of America (USA) 0.01
Section of Biomedical Genetics, BU, United States of America (USA) 0.01
Institute for Memory Impairments and Neurological Disorders (MIND), UCI, United States of America (USA) 0.01
UC Davis Department of Neurology, United States of America (USA) 0.01
University of North Texas Health Science Center at Fort Worth (UNTHSC), United States of America (USA) 0.01
Department of Neurology, UCI, United States of America (USA) 0.01
Department of Neurology, UM, United States of America (USA) 0.01
Fred Hutchinson Cancer Research Center (FHCRC), United States of America (USA) 0.01
Department of Pathology and Laboratory Medicine, IUPUI, United States of America (USA) 0.01
Department of Pathology, UW, United States of America (USA) 0.01
Saul R. Korey Department of Neurology, Einstein, United States of America (USA) 0.01
UC Davis Department of Pathology and Laboratory Medicine, United States of America (USA) 0.01
KU Alzheimer's Disease Center (ADC), United States of America (USA) 0.01
USF Health Byrd Alzheimer's Institute, USF, United States of America (USA) 0.01
Department of Neurology, MGH, United States of America (USA) 0.01
Department of Medicine, UW-Madison, United States of America (USA) 0.01
Duke Department of Psychiatry and Behavioral Sciences, United States of America (USA) 0.01
Department of Pathology and Immunology, WUSTL, United States of America (USA) 0.01
UK Sanders-Brown Center on Aging (SBCoA), United States of America (USA) 0.01
Mesulam Center for Cognitive Neurology and Alzheimer's Disease, NU, United States of America (USA) 0.01
Geriatrics Research Education and Clinical Center (GRECC), VAPSHCS, United States of America (USA) 0.01
Duke Department of Medicine, United States of America (USA) 0.01
UCLA Department of Neurology, United States of America (USA) 0.01
NYU Department of Psychiatry, United States of America (USA) 0.01
Department of Neurosciences, UC San Diego, United States of America (USA) 0.01
Department of Neurology, IUPUI, United States of America (USA) 0.01
Tanz Centre for Research in Neurodegenerative Diseases (Tanz CRND), U of T, Canada 0.01
Rush Department of Neurological Sciences, United States of America (USA) 0.01
Rush Department of Pathology, United States of America (USA) 0.01
Department of Biostatistics, BU, United States of America (USA) 0.01
Rush Alzheimer’s Disease Center (RADC), United States of America (USA) 0.01
Alzheimer's Disease and Memory Disorders Center, BCM, United States of America (USA) 0.01
Evelyn F. McKnight Brain Institute, UM, United States of America (USA) 0.01
Wien Center for Alzheimer's Disease and Memory Disorders, MSMC, United States of America (USA) 0.01
Center for Applied Genomics (CAG), CHOP, United States of America (USA) 0.01
UAB Department of Pathology, United States of America (USA) 0.01
Mayo Clinic Department of Laboratory Medicine and Pathology (DLMP), United States of America (USA) 0.01
OHSU Department of Pathology, United States of America (USA) 0.01
Lou Ruvo Center for Brain Health, Cleveland Clinic, United States of America (USA) 0.01
Department of Clinical Sciences, UT Southwestern Medical Center, United States of America (USA) 0.01
USC Department of Pathology, United States of America (USA) 0.01
Pfizer Worldwide Research & Development (WRD), United States of America (USA) 0.01
School of Nursing, UW, United States of America (USA) 0.01
NYU Division of Pulmonary, Critical Care and Sleep Medicine, United States of America (USA) 0.01
Department of Neurology and Neurotherapeutics, UT Southwestern Medical Center, United States of America (USA) 0.01
Department of Psychiatry and Behavioral Sciences, JHU, United States of America (USA) 0.01
Department of Pathology, U-M, United States of America (USA) 0.01
Department of Pathology, JHU, United States of America (USA) 0.01
Department of Surgery, UT Southwestern Medical Center, United States of America (USA) 0.01
UNC Department of Genetics, United States of America (USA) 0.01
Department of Neurobiology and Behavior, UCI, United States of America (USA) 0.01
UCSF Memory and Aging Center, United States of America (USA) 0.01
Department of Pathology and Laboratory Medicine (BUMC), BU, United States of America (USA) 0.01
Department of Neurology, CU Anschutz, United States of America (USA) 0.01
Portland VA Medical Center (PVAMC), United States of America (USA) 0.01
OHSU Department of Neurology, United States of America (USA) 0.01
BYU Department of Biology, United States of America (USA) 0.01
Duke Department of Pathology, United States of America (USA) 0.01
Department of Pathology and Laboratory Medicine, UCI, United States of America (USA) 0.01
Swedish Medical Center, United States of America (USA) 0.01
Department of Epidemiology, UW, United States of America (USA) 0.01
UCL Department of Molecular Neuroscience, United Kingdom (UK) 0.01
Nash Family Department of Neuroscience, ISMMS, United States of America (USA) 0.01
Department of Genetics and Genomic Sciences, ISMMS, United States of America (USA) 0.01
C. S. Kubik Laboratory for Neuropathology, MGH, United States of America (USA) 0.01
Alzheimer Disease Research Center (ADRC), Pitt, United States of America (USA) 0.01
Institute for Computational Biology (ICB), United States of America (USA) 0.01
Stanford Department of Pathology, United States of America (USA) 0.01
Department of Human Genetics, Pitt, United States of America (USA) 0.01
Department of Psychiatry, UT Southwestern Medical Center, United States of America (USA) 0.01
Department of Neurology and Neurosurgery, JHU, United States of America (USA) 0.01
Kaiser Permanente Washington Health Research Institute (KPWHRI), United States of America (USA) 0.01
Center for Translational and Computational Neuroimmunology, CU, United States of America (USA) 0.01
Department of Psychiatry, Penn, United States of America (USA) 0.01
Department of Psychiatry and Behavioral Sciences, VU, United States of America (USA) 0.01
Department of Psychiatry, ISMMS, United States of America (USA) 0.01
Mayo Clinic's Campus in Arizona, United States of America (USA) 0.01
Department of Pharmacology and Neuroscience, UNT, United States of America (USA) 0.01
Department of Pathology, NU, United States of America (USA) 0.01
National Alzheimer's Coordinating Center (NACC), United States of America (USA) 0.01
Department of Radiology and Imaging Sciences, IUPUI, United States of America (USA) 0
Schepens Eye Research Institute, MEEI, United States of America (USA) 0
Harvard Department of Ophthalmology, United States of America (USA) 0
University of Wisconsin-Madison (UW-Madison), United States of America (USA) 0
Madison VA Geriatrics Research Education and Clinical Center (GRECC), United States of America (USA) 0
Wisconsin Alzheimer's Disease Research Center (ADRC), UW-Madison, United States of America (USA) 0
Michigan Alzheimer's Disease Center (MADC), U-M, United States of America (USA) 0
Department of Neurology, U-M, United States of America (USA) 0
Department of Pathology, UC San Diego, United States of America (USA) 0
Department of Neurology, TTUHSC, United States of America (USA) 0
San Antonio Geriatric Research, Education and Clinical Center (GRECC), STVHCS, United States of America (USA) 0
UCLA Department of Pathology and Laboratory Medicine, United States of America (USA) 0
UK Department of Anatomy and Neurobiology, United States of America (USA) 0
USC Department of Psychiatry and Behavioral Sciences, United States of America (USA) 0
NYU Alzheimer's Disease Center, United States of America (USA) 0
UT Long School of Medicine, UT Health San Antonio, United States of America (USA) 0
Ken and Ruth Davee Department of Neurology, NU, United States of America (USA) 0
Department of Neurology, WUSTL, United States of America (USA) 0
Department of Pharmacology and Neuroscience, TTUHSC, United States of America (USA) 0
UK Department of Biostatistics, United States of America (USA) 0
Rush Department of Internal Medicine, United States of America (USA) 0
UK Department of Epidemiology, United States of America (USA) 0
Department of Neurology, UW, United States of America (USA) 0
Department of Genome Sciences, UW, United States of America (USA) 0
Partners HealthCare Center for Personalized Genetic Medicine (PCPGM), United States of America (USA) 0
Department of Psychiatry, WUSTL, United States of America (USA) 0
Hope Center Program on Protein Aggregation and Neurodegeneration (HPAN), WUSTL, United States of America (USA) 0
Alzheimer's Disease Research Center (ADRC), Emory University, United States of America (USA) 0
Department of Pathology and Laboratory Medicine, Emory University, United States of America (USA) 0
Rush Institute for Healthy Aging, United States of America (USA) 0
Indiana Alzheimer Disease Center, IUPUI, United States of America (USA) 0
Department of Psychology, Pitt, United States of America (USA) 0
Department of Neurology, Pitt, United States of America (USA) 0
Department of Psychiatry, MGH, United States of America (USA) 0
Department of Clinical Neurosciences, University of Cambridge, United Kingdom (UK) 0
Harvard Department of Epidemiology, United States of America (USA) 0
Cambridge Institute for Medical Research (CIMR), University of Cambridge, United Kingdom (UK) 0
Department of Psychiatry, Pitt, United States of America (USA) 0
Department of Epidemiology, CU, United States of America (USA) 0
New York Brain Bank (NYBB), CU, United States of America (USA) 0
Department of Pathology and Cell Biology, CU, United States of America (USA) 0
New York-Presbyterian Hospital, United States of America (USA) 0
Department of Epidemiology, BU, United States of America (USA) 0
Arizona State University (ASU), United States of America (USA) 0
The University of Arizona (Arizona), United States of America (USA) 0
Geriatric Research, Education and Clinical Center (GRECC), VAAAHS, United States of America (USA) 0

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