Generation of Alkyl Radical through Direct Excitation of Boracene-Based Alkylborate

Journal: Journal of the American Chemical Society

Published: 2020-05-12

DOI: 10.1021/jacs.0c04456

Affiliations: 5

Authors: 6

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Research Highlight

Illuminating new corners of photochemistry

© MirageC/Getty

© MirageC/Getty

A metal-catalyst-free method for capturing energy from visible light to drive the formation of complex organic molecules has been developed.

Photoredox catalysis has recently emerged as a powerful method for forming new carbon–carbon bonds from carbon free-radical intermediates. It can give ready access to complex organic structures such as those used in pharmaceuticals. However, the metal catalysts used can complicate the reaction.

Now, a team co-led by scientists at Kanazawa University has developed a metal-free method for generating the same type of carbon free-radical intermediate.

They produced an easy-to-make boron-based radical precursor that released the desired carbon radical under visible light. The radical can go on to participate in a range of new bond-forming reactions, while the boron component can be recovered and reused.

Supported content

  1. Journal of the American Chemical Society 142, 9938–9943 (2020). doi: 10.1021/jacs.0c04456
Institutions Share
Kanazawa University (KU), Japan 0.50
RIKEN Center for Biosystems Dynamics Research (BDR), Japan 0.17
RIKEN Center for Emergent Matter Science (CEMS), Japan 0.17
Tokyo Medical and Dental University (TMDU), Japan 0.08
Japan Science and Technology Agency (JST), Japan 0.08