Journal: Current Biology
Affiliations: 5Go to article
Island species outfoxes genetic fate
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Housecat-sized Channel Island foxes are surprisingly healthy, given they have the lowest genetic variation in the animal kingdom, according to a study published in Current Biology.
The Channel Islands, off the coast of California are home to a ‘dwarf’ fox believed to have descended from the mainland grey fox. Having persisted for thousands of years at very small population sizes, they are a popular model for examining, in a natural environment, the effects of ‘deleterious mutations’ - genetic changes that increase susceptibility to diseases.
A team, including a researcher from Sichuan University, sequenced the complete set of DNA in foxes from six of the islands, including two foxes from San Nicolas and a mainland grey fox. Genomic variation is thought to be key to a species’ ability to withstand threats, yet the team found these foxes to be quite healthy - despite high levels of deleterious mutations and very low genetic variation. The San Nicolas Island foxes had effectively no genetic variation.
- Current Biology 2016; 26, 1183–1189. doi: 10.1016/j.cub.2016.02.062
|University of California, Los Angeles (UCLA), United States of America (USA)||0.71|
|Sichuan University (SCU), China||0.13|
|Princeton University, United States of America (USA)||0.13|
|UCLA Health, United States of America (USA)||0.04|